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The map label for this gene is arsB [H]

Identifier: 85860780

GI number: 85860780

Start: 2951524

End: 2952687

Strand: Direct

Name: arsB [H]

Synonym: SYN_00340

Alternate gene names: 85860780

Gene position: 2951524-2952687 (Clockwise)

Preceding gene: 85860779

Following gene: 85860781

Centisome position: 92.84

GC content: 51.89

Gene sequence:

>1164_bases
ATGAAGATGATTTTTGCTTCAATGTGGTGCGAGACGGTCATATGCTCAGGCAGAAGGAGGAGCGGAAAAAAAATGGCACA
AGCTGAAGAAAAACGACTTTCTTTTTTGGACCGGTTTTTAACCCTGTGGATTTTTCTGGCCATGTTCGTCGGCGTGATGG
GGGGATACCTCTATCCCGGAATCCGGGACGTCATCAACATCTTCCAGGTCGGCACAACCAATATCCCCATCGCCATCGGT
CTGATCCTGATGATGTATCCCCCCCTGGCCAAGGTCAAGTATGAAAAGCTGGGCCAGGTTTTCACTAACGGCAAGGTACT
GGCCCTTTCGCTTGTTCAGAACTGGATTATTGGTCCGATTCTGATGTTCCTGCTGGCGATCACCTTTCTTTCCGGCTATC
ATGAATACATGGTGGGCCTCATCCTTATCGGCCTCGCCCGCTGCATCGCCATGGTCATCGTCTGGAACGATCTGGCCGAA
GGCGACCGGGAATACTGCGCCGGCCTCGTCGCCTTCAACTCGATCTTTCAGGTCCTCTTCTTTTCCGTTTACGCTTATAT
CTTCATTACGATTCTTCCAACGTGGGTCGGGCTTAAAGGGGCCGTCGTCGACATCTCCATCGGGCAGATCGCCGAGAGCG
TATTCATTTATCTGGGCATTCCCTTCATCGCGGGGATCATTTCCCGTTTCGTCGGGCTGAAGACGAAGGGGATCCTCTGG
TATGAAGAGAAATTCATCCCGAGGATCAGTCCCATCACCCTGATCGCCCTGCTTTTTACCATCCTCGTCATGTTCTCCCT
GAAAGGGGAATATATCGTTGAACTGCCCATGGATGTCGTCCGCGTGGCCGTCCCTCTTTTCATTTACTTTGTGGTCATGT
TCTTCGTGTCTTTCTTTCTGTCCATGAAAGTCCGGGCTACGTACGAAGAGTCCACGACCCTGAGTTTTACCGCCGCCTCC
AATAATTTCGAACTCGCCATCGCCGTGGCCATCGCCGTCTTCGGAATCAATTCCGGAGAGGCCTTTGCCTGCGTCATTGG
CCCTTTGCTGGAGGTACCGGTCCTTATCTCTCTGGTGAACGTGGCCCTCTGGTTCAAGAAGAAATACTTCCCTCATACCA
AGGCGACTCCTACCGGGGTTTGCCATGTAACTTGTGAGAATTAG

Upstream 100 bases:

>100_bases
CAGACGGGAGGAAATCTCATGCCACAAGGAAGAGGTCTGCGAAGAATCAGGATACTGAACACATTTCCAAGCGGAAATAT
GATTTGACGCAGATTTCAGC

Downstream 100 bases:

>100_bases
TAATATATGAAAGGAGAAAGGGATTGAAAGAGCGTTATAAACTTTTAATTATTGCGCTGACCTTTCTGGGGGCCTACTTC
ATCCCCTGGACTCATCCCGT

Product: arsenic resistance protein acr3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKMIFASMWCETVICSGRRRSGKKMAQAEEKRLSFLDRFLTLWIFLAMFVGVMGGYLYPGIRDVINIFQVGTTNIPIAIG
LILMMYPPLAKVKYEKLGQVFTNGKVLALSLVQNWIIGPILMFLLAITFLSGYHEYMVGLILIGLARCIAMVIVWNDLAE
GDREYCAGLVAFNSIFQVLFFSVYAYIFITILPTWVGLKGAVVDISIGQIAESVFIYLGIPFIAGIISRFVGLKTKGILW
YEEKFIPRISPITLIALLFTILVMFSLKGEYIVELPMDVVRVAVPLFIYFVVMFFVSFFLSMKVRATYEESTTLSFTAAS
NNFELAIAVAIAVFGINSGEAFACVIGPLLEVPVLISLVNVALWFKKKYFPHTKATPTGVCHVTCEN

Sequences:

>Translated_387_residues
MKMIFASMWCETVICSGRRRSGKKMAQAEEKRLSFLDRFLTLWIFLAMFVGVMGGYLYPGIRDVINIFQVGTTNIPIAIG
LILMMYPPLAKVKYEKLGQVFTNGKVLALSLVQNWIIGPILMFLLAITFLSGYHEYMVGLILIGLARCIAMVIVWNDLAE
GDREYCAGLVAFNSIFQVLFFSVYAYIFITILPTWVGLKGAVVDISIGQIAESVFIYLGIPFIAGIISRFVGLKTKGILW
YEEKFIPRISPITLIALLFTILVMFSLKGEYIVELPMDVVRVAVPLFIYFVVMFFVSFFLSMKVRATYEESTTLSFTAAS
NNFELAIAVAIAVFGINSGEAFACVIGPLLEVPVLISLVNVALWFKKKYFPHTKATPTGVCHVTCEN
>Mature_387_residues
MKMIFASMWCETVICSGRRRSGKKMAQAEEKRLSFLDRFLTLWIFLAMFVGVMGGYLYPGIRDVINIFQVGTTNIPIAIG
LILMMYPPLAKVKYEKLGQVFTNGKVLALSLVQNWIIGPILMFLLAITFLSGYHEYMVGLILIGLARCIAMVIVWNDLAE
GDREYCAGLVAFNSIFQVLFFSVYAYIFITILPTWVGLKGAVVDISIGQIAESVFIYLGIPFIAGIISRFVGLKTKGILW
YEEKFIPRISPITLIALLFTILVMFSLKGEYIVELPMDVVRVAVPLFIYFVVMFFVSFFLSMKVRATYEESTTLSFTAAS
NNFELAIAVAIAVFGINSGEAFACVIGPLLEVPVLISLVNVALWFKKKYFPHTKATPTGVCHVTCEN

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=336, Percent_Identity=36.3095238095238, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 43248; Mature: 43248

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMIFASMWCETVICSGRRRSGKKMAQAEEKRLSFLDRFLTLWIFLAMFVGVMGGYLYPG
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IRDVINIFQVGTTNIPIAIGLILMMYPPLAKVKYEKLGQVFTNGKVLALSLVQNWIIGPI
HHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LMFLLAITFLSGYHEYMVGLILIGLARCIAMVIVWNDLAEGDREYCAGLVAFNSIFQVLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
FSVYAYIFITILPTWVGLKGAVVDISIGQIAESVFIYLGIPFIAGIISRFVGLKTKGILW
HHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
YEEKFIPRISPITLIALLFTILVMFSLKGEYIVELPMDVVRVAVPLFIYFVVMFFVSFFL
EHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
SMKVRATYEESTTLSFTAASNNFELAIAVAIAVFGINSGEAFACVIGPLLEVPVLISLVN
HHHHHEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VALWFKKKYFPHTKATPTGVCHVTCEN
HHHHHHHHCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure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HHHHHHHHCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]