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The map label for this gene is kfoC [H]

Identifier: 85860115

GI number: 85860115

Start: 2323137

End: 2323928

Strand: Direct

Name: kfoC [H]

Synonym: SYN_00822

Alternate gene names: 85860115

Gene position: 2323137-2323928 (Clockwise)

Preceding gene: 85860114

Following gene: 85860116

Centisome position: 73.07

GC content: 43.18

Gene sequence:

>792_bases
ATGCTAAGCATCATAACCCCAGTGTTCAACGGGATACGCTTCATCGAGTTCTGTATTGCGAATGTCATTGAACAGAGGTG
TCCTGACTTGGAACACCTCATCATCGATGGCGGCTCCACCGACGGGACCGTTGAAATCATCAAATCCCACGCGGGACGCC
ACAATCACATCAGATGGCTGTCAGAGAAGGACGAGGGACAGTCCGACGCCATGAACAAGGGCATTCAAATGGCCAAAGGC
GATATCGTGGGGTTCCTTAATGTGGACGATTATTACTCTCCGAGGGCTTTACTCGAGGCGGTTAATTTTATGAAACCCCT
CCCCGAACCTTCACTGTTGGTTGGAAACTGTAACGTTTGGGACAATAACGGCAAACTTTGGTTCATCAGCAGACCAGCCA
AAATTGGTCTCAATAATTTATTGCTTGGGAGGTTCATGGAAGCATTTCCCATGAACCCTTCTGCATATTTTTTCCACAAA
TCTTTACATGACCGAATTGGCCAATATGAGATAGATGAACATTATGGGATGGATGTGCATTTTATCTTTAAGGCAGTACA
GCAGGCCTCTGTCACCTATGTGGATAGAACTTGGGGTAACTATAGATATCTTGAGGGAACTAAAACTTACAAGGATGACA
AGAGTGGTGGCAATGCAGCTAGAGTAAAAGGAATTACTGAATACTATAGGAGAAAGCAAAAGACATATTATCAAATATAT
CTGACCATTCTCGATACTTATTTAAAAACCACAAAATTTTTTAACAACCTTCTGATCCCACGAAAGCAATAG

Upstream 100 bases:

>100_bases
TATGCGGGAAGCATTTATGAAATACTCTCGTCCATAATGAAGGGCAGTAAAAAATGACGGAATCGTTGAGAGCTAAAAAG
GTTTTTCGAAAAGGGGCAGT

Downstream 100 bases:

>100_bases
ATGGGCTATTCCTCTTTCATATCGATTATAATCCCAACCTACAACCGGGCACAGATGCTGCCGTTGACTCTGGACAGTTT
TCTTGCCCAAGATTACCCGA

Product: cell wall biogenesis glycosyltransferase

Products: NA

Alternate protein names: CS; Chondroitin polymerase; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase; UDP-GalNAc transferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase; UDP-GlcUA transferase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MLSIITPVFNGIRFIEFCIANVIEQRCPDLEHLIIDGGSTDGTVEIIKSHAGRHNHIRWLSEKDEGQSDAMNKGIQMAKG
DIVGFLNVDDYYSPRALLEAVNFMKPLPEPSLLVGNCNVWDNNGKLWFISRPAKIGLNNLLLGRFMEAFPMNPSAYFFHK
SLHDRIGQYEIDEHYGMDVHFIFKAVQQASVTYVDRTWGNYRYLEGTKTYKDDKSGGNAARVKGITEYYRRKQKTYYQIY
LTILDTYLKTTKFFNNLLIPRKQ

Sequences:

>Translated_263_residues
MLSIITPVFNGIRFIEFCIANVIEQRCPDLEHLIIDGGSTDGTVEIIKSHAGRHNHIRWLSEKDEGQSDAMNKGIQMAKG
DIVGFLNVDDYYSPRALLEAVNFMKPLPEPSLLVGNCNVWDNNGKLWFISRPAKIGLNNLLLGRFMEAFPMNPSAYFFHK
SLHDRIGQYEIDEHYGMDVHFIFKAVQQASVTYVDRTWGNYRYLEGTKTYKDDKSGGNAARVKGITEYYRRKQKTYYQIY
LTILDTYLKTTKFFNNLLIPRKQ
>Mature_263_residues
MLSIITPVFNGIRFIEFCIANVIEQRCPDLEHLIIDGGSTDGTVEIIKSHAGRHNHIRWLSEKDEGQSDAMNKGIQMAKG
DIVGFLNVDDYYSPRALLEAVNFMKPLPEPSLLVGNCNVWDNNGKLWFISRPAKIGLNNLLLGRFMEAFPMNPSAYFFHK
SLHDRIGQYEIDEHYGMDVHFIFKAVQQASVTYVDRTWGNYRYLEGTKTYKDDKSGGNAARVKGITEYYRRKQKTYYQIY
LTILDTYLKTTKFFNNLLIPRKQ

Specific function: Catalyzes the polymerization of chondroitin, a polysaccharide composed of a repeating disaccharide of N- acetylgalactosamine (GalNAc) and glucuronic acid (GlcUA) units. Each unit has the composition in beta-(1->4)-GlcUA-beta-(1->3)- GalNAc [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. CS/HAS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790044, Length=118, Percent_Identity=37.2881355932203, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788368, Length=110, Percent_Identity=39.0909090909091, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.4.1.175; =2.4.1.226 [H]

Molecular weight: Translated: 30366; Mature: 30366

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIITPVFNGIRFIEFCIANVIEQRCPDLEHLIIDGGSTDGTVEIIKSHAGRHNHIRWL
CCEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCCCCCCEEEC
SEKDEGQSDAMNKGIQMAKGDIVGFLNVDDYYSPRALLEAVNFMKPLPEPSLLVGNCNVW
CCCCCCHHHHHHHCCEEECCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECCEEE
DNNGKLWFISRPAKIGLNNLLLGRFMEAFPMNPSAYFFHKSLHDRIGQYEIDEHYGMDVH
ECCCEEEEEECCHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEHHHCCCHHH
FIFKAVQQASVTYVDRTWGNYRYLEGTKTYKDDKSGGNAARVKGITEYYRRKQKTYYQIY
HHHHHHHHHCEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LTILDTYLKTTKFFNNLLIPRKQ
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLSIITPVFNGIRFIEFCIANVIEQRCPDLEHLIIDGGSTDGTVEIIKSHAGRHNHIRWL
CCEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCCCCCCEEEC
SEKDEGQSDAMNKGIQMAKGDIVGFLNVDDYYSPRALLEAVNFMKPLPEPSLLVGNCNVW
CCCCCCHHHHHHHCCEEECCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECCEEE
DNNGKLWFISRPAKIGLNNLLLGRFMEAFPMNPSAYFFHKSLHDRIGQYEIDEHYGMDVH
ECCCEEEEEECCHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEHHHCCCHHH
FIFKAVQQASVTYVDRTWGNYRYLEGTKTYKDDKSGGNAARVKGITEYYRRKQKTYYQIY
HHHHHHHHHCEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LTILDTYLKTTKFFNNLLIPRKQ
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11943778 [H]