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The map label for this gene is hsdM [C]

Identifier: 85859881

GI number: 85859881

Start: 2113299

End: 2114846

Strand: Direct

Name: hsdM [C]

Synonym: SYN_00494

Alternate gene names: 85859881

Gene position: 2113299-2114846 (Clockwise)

Preceding gene: 85859880

Following gene: 85859882

Centisome position: 66.47

GC content: 48.58

Gene sequence:

>1548_bases
ATGGCCAATAATAACAACAAAACGGAAGCTTTCGAAAAAACCCTATTCAAAGCGGCAGACAAGCTACGCAAAAACATGGA
TGCGGCGGAATATAAGCATATAGTGCTGGGCCTCATCTTCCTCAAATACATTTCCGATTCATTCGAAGCCCTTTATGAAA
AAATAAAAGAAGGCAAAGGTGATTTTGAAGGAGCTGATCCAGAAGATCCCGATGAATACAGGGCGGAAAATGTCTTTTTT
GTTCCGCAAGCGGCCAGATGGTCATATCTTCACTCAAGGGCCAAGCTTCCTTCCATCGGCAAGGATGTCGACGATGCGAT
GGAAGCCATCGAGAAGGAAAACCAGACGCTCAAGGGAATCCTTCCCCAAGTCTATGCCCGTCCCAATTTGGATAAAGCCG
CTTTGGGCGGCCTGATCGACCTTGTCGGCAATATCGCCTTGGGCACTGAAGCCGCCAAAGCGAAAGACCTGCTCGGCAGG
GTTTATGAGTATTTCCTCGGCGAGTTCGCCAACGCCGAAGGGAAAAAGGGCGGACAGTTCTATACTCCCAAATCCATCGT
CCGTTTGATGGTCGAGATGATTGAACCGTTCAAGGGCCGGGTTTACGACCCCTGCTGCGGCAGCGGTGGCATGTTCATCA
TGAGCGAACGTTTCGTGGAAAACCACCAAGGAAAAGTCGATGACATTTCCATCTTCGGACAGGAAAGCAACCAAACGACA
TATCGCCTGTGCCGGATGAATCTGGCAATCCGAGGGATTGACGGCTCGCAAGTCAAATGGAACACTGAAGGTTCGTTTCT
TAATGATGTCCACAAAGACTTGAAGTCGGATTTTATCCTAGCCAATCCGCCTTTTAATGACAGCGACTGGTCCGGCCAAC
TCCTCCAAAGTGATCCCCGCTGGAAATACGGTGTCCCTCAGGCTGCCAACGCCAACTTCGCTTGGCTGCAGCACATGATT
TATCATCTGTCCCCCAAAGGGATCATGGCCTGCGTCCTGGCCAACGGTTCACTCTCCAGCCAAACCAATAATGAGGGAGA
AATCCGTAAATCCTTGGTTGAAAACGATTTGGTAGATTGCATCGTGGCTCTTCCGAAACAGCTTTTCTACAACACCGGGA
TTCCGGCTTGCCTTTGGTTCCTCTCCAGGAAACGTGCGGGTAATGGTGACAGGAAGAGAAGCAGCGAGATTCTTTTTATA
GATGCCAGCGAAGAAGGCTTCATGGAGGACCGCACCCATCGCGCCTTCAGTGACGATGATATCGCAAAAATAGCGGGAAC
TTATCATGAATGGCGGAAGCAGGGCGGGAAATATGAAGACGTTAGAGGATTCTGCAAGTCTGCTGATATAGAAGAAATAA
CCAAGCATAATTTCGTTTTGATGCCTGGGCGCTATGTCGGAATCAAAGATGAGGAGGATGACGGAATACCGTTTGAGGAC
AAGATGGCGGGATATCTCAGTGAGCTTTCAATACAGATGGCGGAAGAAAAGAGACTGGATGAAGAAATAAAAAAGCAGCT
CGGTAATATCGGGCTTAAATTGAAATAA

Upstream 100 bases:

>100_bases
TTAAGCCAAGGGCCATTCATTTGTTTTTTCGGCCATTTGTGATAGCCTGAAGGCAGATATATCAATTATGACATATTAAA
AAAGAAAGATTAGCATTCTT

Downstream 100 bases:

>100_bases
CCATGGAAATAAAAACTTCGGCAATACCAAGCGACTGGAAAATGATGACGTTAGGACAAGTAGGTGTTACCGTCACAGGC
AAAACCCCATCAAAAGATAA

Product: type I restriction-modification system methylation subunit

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MANNNNKTEAFEKTLFKAADKLRKNMDAAEYKHIVLGLIFLKYISDSFEALYEKIKEGKGDFEGADPEDPDEYRAENVFF
VPQAARWSYLHSRAKLPSIGKDVDDAMEAIEKENQTLKGILPQVYARPNLDKAALGGLIDLVGNIALGTEAAKAKDLLGR
VYEYFLGEFANAEGKKGGQFYTPKSIVRLMVEMIEPFKGRVYDPCCGSGGMFIMSERFVENHQGKVDDISIFGQESNQTT
YRLCRMNLAIRGIDGSQVKWNTEGSFLNDVHKDLKSDFILANPPFNDSDWSGQLLQSDPRWKYGVPQAANANFAWLQHMI
YHLSPKGIMACVLANGSLSSQTNNEGEIRKSLVENDLVDCIVALPKQLFYNTGIPACLWFLSRKRAGNGDRKRSSEILFI
DASEEGFMEDRTHRAFSDDDIAKIAGTYHEWRKQGGKYEDVRGFCKSADIEEITKHNFVLMPGRYVGIKDEEDDGIPFED
KMAGYLSELSIQMAEEKRLDEEIKKQLGNIGLKLK

Sequences:

>Translated_515_residues
MANNNNKTEAFEKTLFKAADKLRKNMDAAEYKHIVLGLIFLKYISDSFEALYEKIKEGKGDFEGADPEDPDEYRAENVFF
VPQAARWSYLHSRAKLPSIGKDVDDAMEAIEKENQTLKGILPQVYARPNLDKAALGGLIDLVGNIALGTEAAKAKDLLGR
VYEYFLGEFANAEGKKGGQFYTPKSIVRLMVEMIEPFKGRVYDPCCGSGGMFIMSERFVENHQGKVDDISIFGQESNQTT
YRLCRMNLAIRGIDGSQVKWNTEGSFLNDVHKDLKSDFILANPPFNDSDWSGQLLQSDPRWKYGVPQAANANFAWLQHMI
YHLSPKGIMACVLANGSLSSQTNNEGEIRKSLVENDLVDCIVALPKQLFYNTGIPACLWFLSRKRAGNGDRKRSSEILFI
DASEEGFMEDRTHRAFSDDDIAKIAGTYHEWRKQGGKYEDVRGFCKSADIEEITKHNFVLMPGRYVGIKDEEDDGIPFED
KMAGYLSELSIQMAEEKRLDEEIKKQLGNIGLKLK
>Mature_514_residues
ANNNNKTEAFEKTLFKAADKLRKNMDAAEYKHIVLGLIFLKYISDSFEALYEKIKEGKGDFEGADPEDPDEYRAENVFFV
PQAARWSYLHSRAKLPSIGKDVDDAMEAIEKENQTLKGILPQVYARPNLDKAALGGLIDLVGNIALGTEAAKAKDLLGRV
YEYFLGEFANAEGKKGGQFYTPKSIVRLMVEMIEPFKGRVYDPCCGSGGMFIMSERFVENHQGKVDDISIFGQESNQTTY
RLCRMNLAIRGIDGSQVKWNTEGSFLNDVHKDLKSDFILANPPFNDSDWSGQLLQSDPRWKYGVPQAANANFAWLQHMIY
HLSPKGIMACVLANGSLSSQTNNEGEIRKSLVENDLVDCIVALPKQLFYNTGIPACLWFLSRKRAGNGDRKRSSEILFID
ASEEGFMEDRTHRAFSDDDIAKIAGTYHEWRKQGGKYEDVRGFCKSADIEEITKHNFVLMPGRYVGIKDEEDDGIPFEDK
MAGYLSELSIQMAEEKRLDEEIKKQLGNIGLKLK

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=261, Percent_Identity=24.904214559387, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 58043; Mature: 57912

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANNNNKTEAFEKTLFKAADKLRKNMDAAEYKHIVLGLIFLKYISDSFEALYEKIKEGKG
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DFEGADPEDPDEYRAENVFFVPQAARWSYLHSRAKLPSIGKDVDDAMEAIEKENQTLKGI
CCCCCCCCCCHHHCCCCEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHH
LPQVYARPNLDKAALGGLIDLVGNIALGTEAAKAKDLLGRVYEYFLGEFANAEGKKGGQF
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
YTPKSIVRLMVEMIEPFKGRVYDPCCGSGGMFIMSERFVENHQGKVDDISIFGQESNQTT
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCEEEEECCCCCCHH
YRLCRMNLAIRGIDGSQVKWNTEGSFLNDVHKDLKSDFILANPPFNDSDWSGQLLQSDPR
HHHHHHHHEEECCCCCEEEECCCCHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHCCCCC
WKYGVPQAANANFAWLQHMIYHLSPKGIMACVLANGSLSSQTNNEGEIRKSLVENDLVDC
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
IVALPKQLFYNTGIPACLWFLSRKRAGNGDRKRSSEILFIDASEEGFMEDRTHRAFSDDD
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHCCCCCCH
IAKIAGTYHEWRKQGGKYEDVRGFCKSADIEEITKHNFVLMPGRYVGIKDEEDDGIPFED
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHCCEEECCCEEECCCCCCCCCCCCHH
KMAGYLSELSIQMAEEKRLDEEIKKQLGNIGLKLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ANNNNKTEAFEKTLFKAADKLRKNMDAAEYKHIVLGLIFLKYISDSFEALYEKIKEGKG
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DFEGADPEDPDEYRAENVFFVPQAARWSYLHSRAKLPSIGKDVDDAMEAIEKENQTLKGI
CCCCCCCCCCHHHCCCCEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHH
LPQVYARPNLDKAALGGLIDLVGNIALGTEAAKAKDLLGRVYEYFLGEFANAEGKKGGQF
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
YTPKSIVRLMVEMIEPFKGRVYDPCCGSGGMFIMSERFVENHQGKVDDISIFGQESNQTT
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCEEEEECCCCCCHH
YRLCRMNLAIRGIDGSQVKWNTEGSFLNDVHKDLKSDFILANPPFNDSDWSGQLLQSDPR
HHHHHHHHEEECCCCCEEEECCCCHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHCCCCC
WKYGVPQAANANFAWLQHMIYHLSPKGIMACVLANGSLSSQTNNEGEIRKSLVENDLVDC
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
IVALPKQLFYNTGIPACLWFLSRKRAGNGDRKRSSEILFIDASEEGFMEDRTHRAFSDDD
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHCCCCCCH
IAKIAGTYHEWRKQGGKYEDVRGFCKSADIEEITKHNFVLMPGRYVGIKDEEDDGIPFED
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHCCEEECCCEEECCCCCCCCCCCCHH
KMAGYLSELSIQMAEEKRLDEEIKKQLGNIGLKLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]