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The map label for this gene is prc [H]

Identifier: 85859592

GI number: 85859592

Start: 1825151

End: 1827247

Strand: Direct

Name: prc [H]

Synonym: SYN_02024

Alternate gene names: 85859592

Gene position: 1825151-1827247 (Clockwise)

Preceding gene: 85859591

Following gene: 85859596

Centisome position: 57.41

GC content: 51.26

Gene sequence:

>2097_bases
ATGAGCATGTGCGATAAAAGACCCAGAAACATATCCGAAAACAGTCCCTGGAACTGCCGGGATATCCGATTCGGAGACAA
GTTCCCATATTACTTTCGAAGTTTTATAGTCATTCTGCTGCTGATTCTGCTTTTGCCGTGCTGTTCAGTGTCAGACAATC
TCACCTGTCACAGACTGCCCATGGTGATGCAGAAGTTTCTGGACAACCACTACGCCATGAAGAATATGACCGGGGAGATC
AAGACCCGTGCCGTTGACCAGTTGATCAAAAATCTCGATCCCTCGAAAACGATGCTGTATGAATCAGATGTGAAAAGGCT
GAAGCCGATTCTTCAAAACTTGTTTTCAAGTATGAAAACGGGAAACTGCACCGCACTGCGGGGAGTTTACGATGTCCTCG
TTGCGCGGGCTCGGGAAAACGAGACCGTCGTCAAAGAAATTCTGGGACCGGGCTACAGACATGACGAGACTGTGGAACTG
AGCATCAACGTCGAAAAGCGCCCCTTTGTAAAGACTCTGGCGGAAAAGCATGAACTCCTTCGAAAACTCGTGCACTTCCA
GATTGAAAACGCCCTTCTGTCCGGCATGGACATGGAAGAGGCAAAGAAACAGCAGATTCACCACTATACACTCCAGACAA
GGCGTGTTGTCGAGCATGATCCCGAAGAGCTCATTACGAATGCCGCCAAAGCCTTCGCCTCAGCATTGGATCCTCATACG
AGCTACATGTCCCCTGAAGACTATGAGGACTTTCAGATCCAGATGCAGCTCTCCCTGGAGGGGATCGGGGCCGCTCTCAG
CAGTGACAACGGTTTTGCCGTCATCGAGGAGTTGGTGGCCGGAGGAAGTGCAGCTCGATCCGGCCTGTTGAAACCGAAAG
ATAAAATTATTGCCGTGGCCCAGGAGGGGGAAAAGCCCATCAGCGTTATAGACATGGACCTTCAGGATGTAACCAGGATG
ATTCGCGGCAGGAAGGGCACAAAGGTAACCTTAACGATTTTGAGACAGGCGGAGAGCACATACCGCTTCAACGCCACGAT
CACACGCGATAAGGTGGAACTCAAGGAACAGGAGGCCAAAATCGAATACGTTACCCGGTCAGCAGGTGCCAGGCAGTACC
GTTTCGGTGTGATTGATCTGCCTTCCTTCTACGGTGATGAGAAGGAGGAAAAATCCTGTTATGAAGATGTGAAAAAACTC
CTTATGGAGGCTAAGCGGCAGCGTGTCGATGGCATTGTACTGGATCTTTCACGCAATGGCGGCGGTCTGCTCACGGAGGC
GGTGCGTCTTACAGGCCTTTTTATCGGCAATGGCGGCATTGTGGCAACCAGGGACAGCCGAGGACAGGTTACCATTCTCG
CCAATGGGTCTGCTGCTTCGGAGGTACAGGATGATGAAAGAAAAGTGATTCTGTATCCCGCGGAAGACTCCCAGGAGCTA
TATACAGGACCTCTCGTCGTGTTGACAAGCAGGCTCAGCGCGTCAGCCAGCGAAATCGTCGCGGGAGCTCTCAAGGATTA
CCGTCGCGCGGTGATAGTCGGTTCGGACCATACCTTCGGCAAAGGATCTGTACAAGTCATGATATCCCTGCCCTGGAATC
TGGGCGGCATGACCATCACCAGAGATTTATACTTTCTGCCCGGCGGACGTTCCACACAAAAGACAGGCGTAGAAGCAAAC
GTCATGCTGCCCAACTGGTTCGTTCTTGAAGATATTGGTGAAACGGCATTGGATTACCCTCTTCCGGCCCAGGCAATTAC
GCCCTTTCTTGGTACGCCGGAAAATTTGATTCCACCCTGGAAACCTCTGAACCGCTCTCTTCTGGCTAATCTTGCGGAAC
GGTCTCAAGCCCGGATTGCCAAAGACGTCAAGTTCACGGAAATCATGATGAAAAACCGGGAGGCCGCCTCAAGGCATGGC
ATTATCCGTCTTGCCGACTTACGCAGGGAAATGACGGAAAATAGCGGTAAGAAGAAGGAATCGATCGCTGAGCGCAGGCA
GAAAGCAAGGGATCAGTTTTCTCCTTTTTTGGAGGAGAGCGTGAACGTTCTAACAGATATGATCACACTGAGGAGTCCGG
AACTGGACTTGAGTTGA

Upstream 100 bases:

>100_bases
TCCTCCTATTGTCACACTCATGAAAATTTTTTATTATTCATAACTTATATATCAAGCGGATGGAAATATATGACCAGACG
CCGCAGGATGAATATTAAAT

Downstream 100 bases:

>100_bases
CAGTTGTTGCTGTTGCTGCAATTTTCTTTATTCCCGCTGGCAATCGTTCCTGTATGCAGTAATAATCTTGCGCATGACTC
ATGGCCTTCAGAAAATCAAA

Product: carboxy-terminal processing protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 698; Mature: 697

Protein sequence:

>698_residues
MSMCDKRPRNISENSPWNCRDIRFGDKFPYYFRSFIVILLLILLLPCCSVSDNLTCHRLPMVMQKFLDNHYAMKNMTGEI
KTRAVDQLIKNLDPSKTMLYESDVKRLKPILQNLFSSMKTGNCTALRGVYDVLVARARENETVVKEILGPGYRHDETVEL
SINVEKRPFVKTLAEKHELLRKLVHFQIENALLSGMDMEEAKKQQIHHYTLQTRRVVEHDPEELITNAAKAFASALDPHT
SYMSPEDYEDFQIQMQLSLEGIGAALSSDNGFAVIEELVAGGSAARSGLLKPKDKIIAVAQEGEKPISVIDMDLQDVTRM
IRGRKGTKVTLTILRQAESTYRFNATITRDKVELKEQEAKIEYVTRSAGARQYRFGVIDLPSFYGDEKEEKSCYEDVKKL
LMEAKRQRVDGIVLDLSRNGGGLLTEAVRLTGLFIGNGGIVATRDSRGQVTILANGSAASEVQDDERKVILYPAEDSQEL
YTGPLVVLTSRLSASASEIVAGALKDYRRAVIVGSDHTFGKGSVQVMISLPWNLGGMTITRDLYFLPGGRSTQKTGVEAN
VMLPNWFVLEDIGETALDYPLPAQAITPFLGTPENLIPPWKPLNRSLLANLAERSQARIAKDVKFTEIMMKNREAASRHG
IIRLADLRREMTENSGKKKESIAERRQKARDQFSPFLEESVNVLTDMITLRSPELDLS

Sequences:

>Translated_698_residues
MSMCDKRPRNISENSPWNCRDIRFGDKFPYYFRSFIVILLLILLLPCCSVSDNLTCHRLPMVMQKFLDNHYAMKNMTGEI
KTRAVDQLIKNLDPSKTMLYESDVKRLKPILQNLFSSMKTGNCTALRGVYDVLVARARENETVVKEILGPGYRHDETVEL
SINVEKRPFVKTLAEKHELLRKLVHFQIENALLSGMDMEEAKKQQIHHYTLQTRRVVEHDPEELITNAAKAFASALDPHT
SYMSPEDYEDFQIQMQLSLEGIGAALSSDNGFAVIEELVAGGSAARSGLLKPKDKIIAVAQEGEKPISVIDMDLQDVTRM
IRGRKGTKVTLTILRQAESTYRFNATITRDKVELKEQEAKIEYVTRSAGARQYRFGVIDLPSFYGDEKEEKSCYEDVKKL
LMEAKRQRVDGIVLDLSRNGGGLLTEAVRLTGLFIGNGGIVATRDSRGQVTILANGSAASEVQDDERKVILYPAEDSQEL
YTGPLVVLTSRLSASASEIVAGALKDYRRAVIVGSDHTFGKGSVQVMISLPWNLGGMTITRDLYFLPGGRSTQKTGVEAN
VMLPNWFVLEDIGETALDYPLPAQAITPFLGTPENLIPPWKPLNRSLLANLAERSQARIAKDVKFTEIMMKNREAASRHG
IIRLADLRREMTENSGKKKESIAERRQKARDQFSPFLEESVNVLTDMITLRSPELDLS
>Mature_697_residues
SMCDKRPRNISENSPWNCRDIRFGDKFPYYFRSFIVILLLILLLPCCSVSDNLTCHRLPMVMQKFLDNHYAMKNMTGEIK
TRAVDQLIKNLDPSKTMLYESDVKRLKPILQNLFSSMKTGNCTALRGVYDVLVARARENETVVKEILGPGYRHDETVELS
INVEKRPFVKTLAEKHELLRKLVHFQIENALLSGMDMEEAKKQQIHHYTLQTRRVVEHDPEELITNAAKAFASALDPHTS
YMSPEDYEDFQIQMQLSLEGIGAALSSDNGFAVIEELVAGGSAARSGLLKPKDKIIAVAQEGEKPISVIDMDLQDVTRMI
RGRKGTKVTLTILRQAESTYRFNATITRDKVELKEQEAKIEYVTRSAGARQYRFGVIDLPSFYGDEKEEKSCYEDVKKLL
MEAKRQRVDGIVLDLSRNGGGLLTEAVRLTGLFIGNGGIVATRDSRGQVTILANGSAASEVQDDERKVILYPAEDSQELY
TGPLVVLTSRLSASASEIVAGALKDYRRAVIVGSDHTFGKGSVQVMISLPWNLGGMTITRDLYFLPGGRSTQKTGVEANV
MLPNWFVLEDIGETALDYPLPAQAITPFLGTPENLIPPWKPLNRSLLANLAERSQARIAKDVKFTEIMMKNREAASRHGI
IRLADLRREMTENSGKKKESIAERRQKARDQFSPFLEESVNVLTDMITLRSPELDLS

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=703, Percent_Identity=30.4409672830725, Blast_Score=281, Evalue=8e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 78371; Mature: 78240

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMCDKRPRNISENSPWNCRDIRFGDKFPYYFRSFIVILLLILLLPCCSVSDNLTCHRLP
CCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
MVMQKFLDNHYAMKNMTGEIKTRAVDQLIKNLDPSKTMLYESDVKRLKPILQNLFSSMKT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
GNCTALRGVYDVLVARARENETVVKEILGPGYRHDETVELSINVEKRPFVKTLAEKHELL
CCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
RKLVHFQIENALLSGMDMEEAKKQQIHHYTLQTRRVVEHDPEELITNAAKAFASALDPHT
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
SYMSPEDYEDFQIQMQLSLEGIGAALSSDNGFAVIEELVAGGSAARSGLLKPKDKIIAVA
CCCCCCCCCCEEEEEEEEECHHHHHHCCCCCHHHHHHHHCCCHHHHCCCCCCCCCEEEEE
QEGEKPISVIDMDLQDVTRMIRGRKGTKVTLTILRQAESTYRFNATITRDKVELKEQEAK
CCCCCCCEEEECCHHHHHHHHHCCCCCEEEEEEEHHCCCCEEEEEEEEHHHHHHHHHHHH
IEYVTRSAGARQYRFGVIDLPSFYGDEKEEKSCYEDVKKLLMEAKRQRVDGIVLDLSRNG
HHHHHHCCCCCEEEEEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
GGLLTEAVRLTGLFIGNGGIVATRDSRGQVTILANGSAASEVQDDERKVILYPAEDSQEL
CCHHHHHHHHEEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCH
YTGPLVVLTSRLSASASEIVAGALKDYRRAVIVGSDHTFGKGSVQVMISLPWNLGGMTIT
HCCCHHHHHHHHCCCHHHHHHHHHHHHCEEEEECCCCCCCCCCEEEEEECCCCCCCEEEE
RDLYFLPGGRSTQKTGVEANVMLPNWFVLEDIGETALDYPLPAQAITPFLGTPENLIPPW
EEEEECCCCCCCCCCCCEEEEECCCEEEHHHHCHHHCCCCCCHHHHCCCCCCCHHCCCCC
KPLNRSLLANLAERSQARIAKDVKFTEIMMKNREAASRHGIIRLADLRREMTENSGKKKE
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCCEEHHHHHHHHHHCCCCHHH
SIAERRQKARDQFSPFLEESVNVLTDMITLRSPELDLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SMCDKRPRNISENSPWNCRDIRFGDKFPYYFRSFIVILLLILLLPCCSVSDNLTCHRLP
CCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
MVMQKFLDNHYAMKNMTGEIKTRAVDQLIKNLDPSKTMLYESDVKRLKPILQNLFSSMKT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
GNCTALRGVYDVLVARARENETVVKEILGPGYRHDETVELSINVEKRPFVKTLAEKHELL
CCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
RKLVHFQIENALLSGMDMEEAKKQQIHHYTLQTRRVVEHDPEELITNAAKAFASALDPHT
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
SYMSPEDYEDFQIQMQLSLEGIGAALSSDNGFAVIEELVAGGSAARSGLLKPKDKIIAVA
CCCCCCCCCCEEEEEEEEECHHHHHHCCCCCHHHHHHHHCCCHHHHCCCCCCCCCEEEEE
QEGEKPISVIDMDLQDVTRMIRGRKGTKVTLTILRQAESTYRFNATITRDKVELKEQEAK
CCCCCCCEEEECCHHHHHHHHHCCCCCEEEEEEEHHCCCCEEEEEEEEHHHHHHHHHHHH
IEYVTRSAGARQYRFGVIDLPSFYGDEKEEKSCYEDVKKLLMEAKRQRVDGIVLDLSRNG
HHHHHHCCCCCEEEEEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
GGLLTEAVRLTGLFIGNGGIVATRDSRGQVTILANGSAASEVQDDERKVILYPAEDSQEL
CCHHHHHHHHEEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCH
YTGPLVVLTSRLSASASEIVAGALKDYRRAVIVGSDHTFGKGSVQVMISLPWNLGGMTIT
HCCCHHHHHHHHCCCHHHHHHHHHHHHCEEEEECCCCCCCCCCEEEEEECCCCCCCEEEE
RDLYFLPGGRSTQKTGVEANVMLPNWFVLEDIGETALDYPLPAQAITPFLGTPENLIPPW
EEEEECCCCCCCCCCCCEEEEECCCEEEHHHHCHHHCCCCCCHHHHCCCCCCCHHCCCCC
KPLNRSLLANLAERSQARIAKDVKFTEIMMKNREAASRHGIIRLADLRREMTENSGKKKE
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCCEEHHHHHHHHHHCCCCHHH
SIAERRQKARDQFSPFLEESVNVLTDMITLRSPELDLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]