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The map label for this gene is yaeL [C]

Identifier: 85859437

GI number: 85859437

Start: 1641844

End: 1642944

Strand: Direct

Name: yaeL [C]

Synonym: SYN_00915

Alternate gene names: 85859437

Gene position: 1641844-1642944 (Clockwise)

Preceding gene: 85859436

Following gene: 85859438

Centisome position: 51.64

GC content: 48.96

Gene sequence:

>1101_bases
ATGATCGGACTCAGTATCATATCAGTTGTCATATTGCTGGGTGTTCTTATTTTTGTACATGAATTCGGGCATTTTATCGC
GGCGAAATATTCCGGAGTCGGGGTTCTGAAATTTTCCCTTGGTTTCGGTCCGAAGCTCATCAGTCGCAAGATTGGTGAGA
CCGAGTATCTTCTGTCACTCATTCCTCTTGGAGGGTATGTAAAACTTTTAGGCGAATCCCCGGATGACCTTCTCTCTCCT
GAACAGGAAAAACGGTCTTTCCTGAAACAGCCTGTCTGGAAGCGCATCATCATCGTGGCTGCGGGACCGGTCTTCAATTT
TCTCCTGGCCATCCTTATTTTTAACATAGTCTATATGACAGGGGTTCCGGTTCTTGCGCCGACTGTCGGCGGCATCGAAC
AGGGAAGTGCTGCCTGGAAGGCGGGCATCAAGGAAGGCGATTCCATTCTGACCGTAAACGGCAGAACCATATCCCAGTGG
GACGAACTTGCTGAGGAGATCGGCAGAAGTAAGGGTAAAGCAGTGAAGCTGCGGATCGGGAATGGTGAGCCCCCCAGGGA
AGTGACACTTGTCCCCCAGTTAATGAAAGGGACGAATATTTTCGGGGAAGAGGTGGAAAATTACCGGATAGGAATCAGTG
CGTCTTCAAAGATTCTGATCTCCAGGACGGGACCCTTGAATGCCTTCTGGATGAGCCTCAAACAGACATGGACAATCACA
AAGCTGACCATGGTCAGTATAGTAAAAATGATCGAAGGGGTGGTTTCACCTAAAAATCTTGGAGGGCCTATCCTGATTGC
TCAGATTGCCGGCGCTCAGGTCAAGGAAGGAATCACCCCCTTTGTCCTGTTCATGGCACTGCTCAGCATCAATCTGGCTG
TTCTGAACCTTCTGCCTATCCCGGTTCTTGATGGAGGACACCTCATGTTCTTCATTATTGAGCTGGTCATCGGGAGGGAA
ATCAGTATCCGCTGGAGGGAAGCGGCCCAGCAGGTGGGACTGGTTATTCTGGTCCTCCTTATGGCTTTTGCTTTTGCTAT
GGATATAAGTCGCTTGAACATCGGATTCATCGATGAATTTTTTAAAATGATCGGCAGGTAG

Upstream 100 bases:

>100_bases
TCAGTGCATGACCTCTCCAGAAATCGAAGATATTCTGGAAGCAGATGGGTGGGCACGCAAAGAAACTGAAAAACTTCTAA
AGAGCATGGGGCATTAAAAT

Downstream 100 bases:

>100_bases
AAAGACATGATGACGCTCGCGCTGGATACGTCCTCCAAAACTGTGGGAATTGCCCTTCTTGATGGAGAGGAAATTCTTGC
GGAGACCTTTTTTAACCTGA

Product: membrane metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MIGLSIISVVILLGVLIFVHEFGHFIAAKYSGVGVLKFSLGFGPKLISRKIGETEYLLSLIPLGGYVKLLGESPDDLLSP
EQEKRSFLKQPVWKRIIIVAAGPVFNFLLAILIFNIVYMTGVPVLAPTVGGIEQGSAAWKAGIKEGDSILTVNGRTISQW
DELAEEIGRSKGKAVKLRIGNGEPPREVTLVPQLMKGTNIFGEEVENYRIGISASSKILISRTGPLNAFWMSLKQTWTIT
KLTMVSIVKMIEGVVSPKNLGGPILIAQIAGAQVKEGITPFVLFMALLSINLAVLNLLPIPVLDGGHLMFFIIELVIGRE
ISIRWREAAQQVGLVILVLLMAFAFAMDISRLNIGFIDEFFKMIGR

Sequences:

>Translated_366_residues
MIGLSIISVVILLGVLIFVHEFGHFIAAKYSGVGVLKFSLGFGPKLISRKIGETEYLLSLIPLGGYVKLLGESPDDLLSP
EQEKRSFLKQPVWKRIIIVAAGPVFNFLLAILIFNIVYMTGVPVLAPTVGGIEQGSAAWKAGIKEGDSILTVNGRTISQW
DELAEEIGRSKGKAVKLRIGNGEPPREVTLVPQLMKGTNIFGEEVENYRIGISASSKILISRTGPLNAFWMSLKQTWTIT
KLTMVSIVKMIEGVVSPKNLGGPILIAQIAGAQVKEGITPFVLFMALLSINLAVLNLLPIPVLDGGHLMFFIIELVIGRE
ISIRWREAAQQVGLVILVLLMAFAFAMDISRLNIGFIDEFFKMIGR
>Mature_366_residues
MIGLSIISVVILLGVLIFVHEFGHFIAAKYSGVGVLKFSLGFGPKLISRKIGETEYLLSLIPLGGYVKLLGESPDDLLSP
EQEKRSFLKQPVWKRIIIVAAGPVFNFLLAILIFNIVYMTGVPVLAPTVGGIEQGSAAWKAGIKEGDSILTVNGRTISQW
DELAEEIGRSKGKAVKLRIGNGEPPREVTLVPQLMKGTNIFGEEVENYRIGISASSKILISRTGPLNAFWMSLKQTWTIT
KLTMVSIVKMIEGVVSPKNLGGPILIAQIAGAQVKEGITPFVLFMALLSINLAVLNLLPIPVLDGGHLMFFIIELVIGRE
ISIRWREAAQQVGLVILVLLMAFAFAMDISRLNIGFIDEFFKMIGR

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=232, Percent_Identity=36.6379310344828, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 39952; Mature: 39952

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGLSIISVVILLGVLIFVHEFGHFIAAKYSGVGVLKFSLGFGPKLISRKIGETEYLLSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCHHHHHHH
IPLGGYVKLLGESPDDLLSPEQEKRSFLKQPVWKRIIIVAAGPVFNFLLAILIFNIVYMT
HCCCCHHEEECCCCHHHCCCCHHHHHHHHCCHHHEEEEEECCHHHHHHHHHHHHHHHHHH
GVPVLAPTVGGIEQGSAAWKAGIKEGDSILTVNGRTISQWDELAEEIGRSKGKAVKLRIG
CCCHHHCCCCCCCCCCHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEC
NGEPPREVTLVPQLMKGTNIFGEEVENYRIGISASSKILISRTGPLNAFWMSLKQTWTIT
CCCCCCEEEHHHHHHCCCCCCHHHHCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHH
KLTMVSIVKMIEGVVSPKNLGGPILIAQIAGAQVKEGITPFVLFMALLSINLAVLNLLPI
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
PVLDGGHLMFFIIELVIGREISIRWREAAQQVGLVILVLLMAFAFAMDISRLNIGFIDEF
CEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FKMIGR
HHHHCC
>Mature Secondary Structure
MIGLSIISVVILLGVLIFVHEFGHFIAAKYSGVGVLKFSLGFGPKLISRKIGETEYLLSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCHHHHHHH
IPLGGYVKLLGESPDDLLSPEQEKRSFLKQPVWKRIIIVAAGPVFNFLLAILIFNIVYMT
HCCCCHHEEECCCCHHHCCCCHHHHHHHHCCHHHEEEEEECCHHHHHHHHHHHHHHHHHH
GVPVLAPTVGGIEQGSAAWKAGIKEGDSILTVNGRTISQWDELAEEIGRSKGKAVKLRIG
CCCHHHCCCCCCCCCCHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEC
NGEPPREVTLVPQLMKGTNIFGEEVENYRIGISASSKILISRTGPLNAFWMSLKQTWTIT
CCCCCCEEEHHHHHHCCCCCCHHHHCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHH
KLTMVSIVKMIEGVVSPKNLGGPILIAQIAGAQVKEGITPFVLFMALLSINLAVLNLLPI
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
PVLDGGHLMFFIIELVIGREISIRWREAAQQVGLVILVLLMAFAFAMDISRLNIGFIDEF
CEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FKMIGR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]