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The map label for this gene is frr

Identifier: 85859433

GI number: 85859433

Start: 1638315

End: 1638872

Strand: Direct

Name: frr

Synonym: SYN_00919

Alternate gene names: 85859433

Gene position: 1638315-1638872 (Clockwise)

Preceding gene: 85859432

Following gene: 85859434

Centisome position: 51.53

GC content: 43.37

Gene sequence:

>558_bases
ATGAAGGACATGGTCTTTGACGAACTGAAGCAGAATATGGAAAAAGGATTGCAGGCTCTGGAAAAATCCTTTAACAAAGT
GCGTACGGGAAGAGCTTCAATATCATTGCTTGACGGAATTAAAGCGGATTATTACGGTACACCGACGCCTCTCAATCAGG
TCGCTACCCTTTCTGTTCCGGAAAGTCGGCAGATCCTGATTTCTCCGTGGGATACCAGTGCCCTGAACGCCATAGAAAAG
GCGATTCAGAAATCCGACCTGGGACTCGTTCCGAATAATGACGGCAAGGTTATACGGATTTCTATTCCGCCATTGACTGA
GGCCCGACGGAAGGAACTGGTCAAAGTCGTTAGGAAGATGGCGGAAGAATGCAAGGTTAAACTCAGAAACGCCCGAAGAG
ACGCCAACGAAGAATTCAAATCCATGAAAAAAAATAATGATATTTCCGAAGATCAGATGCATGATTATCAGGATCAGGTT
CAAAAAATGACAGACAGCTATATTGAAAAGTCAGAGGATATTCTCGTACAGAAAGAAAAAGAAATTATGGAGATATAG

Upstream 100 bases:

>100_bases
TAACCATCTGCCCATCCTGGTGTTCAATCTTCAGAAACCCGGCAATATTGTCAGATGTATTTCCGGAATACCCATAGGAA
CCCTTGTTGGAGATTAACAA

Downstream 100 bases:

>100_bases
CCGGTTTCCGGAATTGCATGTTTCTTTTATAATCAGGGAGGGGAGCCAAGAGGCTCCCCCTTTTGTTCAATAGGCGTTTT
TTTACAGCCTGATTTATATC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MKDMVFDELKQNMEKGLQALEKSFNKVRTGRASISLLDGIKADYYGTPTPLNQVATLSVPESRQILISPWDTSALNAIEK
AIQKSDLGLVPNNDGKVIRISIPPLTEARRKELVKVVRKMAEECKVKLRNARRDANEEFKSMKKNNDISEDQMHDYQDQV
QKMTDSYIEKSEDILVQKEKEIMEI

Sequences:

>Translated_185_residues
MKDMVFDELKQNMEKGLQALEKSFNKVRTGRASISLLDGIKADYYGTPTPLNQVATLSVPESRQILISPWDTSALNAIEK
AIQKSDLGLVPNNDGKVIRISIPPLTEARRKELVKVVRKMAEECKVKLRNARRDANEEFKSMKKNNDISEDQMHDYQDQV
QKMTDSYIEKSEDILVQKEKEIMEI
>Mature_185_residues
MKDMVFDELKQNMEKGLQALEKSFNKVRTGRASISLLDGIKADYYGTPTPLNQVATLSVPESRQILISPWDTSALNAIEK
AIQKSDLGLVPNNDGKVIRISIPPLTEARRKELVKVVRKMAEECKVKLRNARRDANEEFKSMKKNNDISEDQMHDYQDQV
QKMTDSYIEKSEDILVQKEKEIMEI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=182, Percent_Identity=30.2197802197802, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI1786368, Length=173, Percent_Identity=52.0231213872832, Blast_Score=179, Evalue=8e-47,
Organism=Drosophila melanogaster, GI24661488, Length=180, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_SYNAS (Q2LTQ4)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_461635.1
- ProteinModelPortal:   Q2LTQ4
- SMR:   Q2LTQ4
- STRING:   Q2LTQ4
- GeneID:   3883141
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_00919
- NMPDR:   fig|56780.10.peg.1577
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q2LTQ4
- BioCyc:   SACI56780:SYN_00919-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21186; Mature: 21186

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDMVFDELKQNMEKGLQALEKSFNKVRTGRASISLLDGIKADYYGTPTPLNQVATLSVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHEEECCCC
ESRQILISPWDTSALNAIEKAIQKSDLGLVPNNDGKVIRISIPPLTEARRKELVKVVRKM
CCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
AEECKVKLRNARRDANEEFKSMKKNNDISEDQMHDYQDQVQKMTDSYIEKSEDILVQKEK
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIMEI
HHHCC
>Mature Secondary Structure
MKDMVFDELKQNMEKGLQALEKSFNKVRTGRASISLLDGIKADYYGTPTPLNQVATLSVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHEEECCCC
ESRQILISPWDTSALNAIEKAIQKSDLGLVPNNDGKVIRISIPPLTEARRKELVKVVRKM
CCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
AEECKVKLRNARRDANEEFKSMKKNNDISEDQMHDYQDQVQKMTDSYIEKSEDILVQKEK
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIMEI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA