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The map label for this gene is yhdR [H]

Identifier: 85859408

GI number: 85859408

Start: 1614742

End: 1615929

Strand: Direct

Name: yhdR [H]

Synonym: SYN_02937

Alternate gene names: 85859408

Gene position: 1614742-1615929 (Clockwise)

Preceding gene: 85859407

Following gene: 85859412

Centisome position: 50.79

GC content: 50.93

Gene sequence:

>1188_bases
ATGCCTATTTCAAATAAAATTCATGGACTGATCACGCGATCCTCCTGGATCAGAAAAATGTTTGAGGAAGGTTTGATTTA
TAAGAAAAAATACGGTCCTGAGAATGTGTATGATTTCACGCTGGGCAATCCTAATGTTCCGCCTCCCTCGGAGTTCGGAG
ATGCCCTGCTGGAAGTTGCCGCCCAGTCCATTCCCGGCAAGCATGGTTACATGCCCAACGCGGGCTATCCTGAAACCCGG
GAAGCGATCGCCGCTTATCTGACTGCCAAATTTCACATACCCCTGACAGCTGATCACATTATCATGACCTGCGGCGCCGC
GGGAGCTTTGAATGTGACCATGAAGACGATTCTGGATCCAGGCGATGAAGTGATTATTCCAACCCCCTATTTTGTGGAGT
ACGAATTCTACGTGGACAACGCCGGAGGGATAAGCCGCCTTGTTCCAACAAAGGAGGATTTCAATCTCGACCTGGAGGCG
ATTCGTTCAGCCTTTACGGAGAAAACCAGGGCCGTTCTGATCAATTCGCCGAACAACCCGACCGGGAGAGTCTACGACGA
GGAAACCATCCGGGGACTTGCAGCCATCATCGAGGAAAAGGGCAGACTTTATAACAGAGCAGTTTACCTGGTTTCAGATG
AGCCATACAGTGACATCGTTTATGACGGGATCAAGGTTCCCTTTATTATGGAGTGCTGCAAGAACAGCATCATTGCTTTT
TCCTATTCCAAATGCCTTTCTGTACCGGGGGAGCGCATCGGATACCTTGCCTTGCATCCGGAACTTGCCGATCTGCAGGA
CGTCCTCAGCGGGATGATCTTCTGCAACCGGATTCTGGGATATATCAATGCCCCCGCCCTGATGCAGAGGGTGATATCCC
ATATTCAGGGGGTACATGTCAATGTGGAAGAGTACAAGAGGAAGCGTGATCTGCTCTGTGAAGGATTGAGCGCCTGTGGA
TATTCCTTTGCCAAACCGGAAGGAACCTTCTATCTCTTTGTGCGTTCACCCATAGCGGATGATGTGACTTATGTCCGGGC
GCTTCAACTGCGTCGCGTTCTCACCACGCCGGGAATCGGGTTCGGCGGGCCGGGCTACTTCAGAATCGCATACTGCGTCG
ATGACGCTGCAATCACAAACGCCATGCCCGGCTTTGCAGACACGTTGAAAGAATATCAGAATCGATGA

Upstream 100 bases:

>100_bases
TGACGACTTATCGGTGCTGTGTTAAGTACTCGGCAGCAGTGAAAATATTTTCCCGCAACTTGATCAATCGCCCCGGGGAA
GAGGCGGAAAGGGAGTCGGC

Downstream 100 bases:

>100_bases
GAAATCATTGTAACTGTGAAGATTCAGGCGTGATCCTTTCATCAGGCTGAATTCCCCATGGCATGGCAGGGTCAGTCATT
GAGATGACCGTCTCATGATG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MPISNKIHGLITRSSWIRKMFEEGLIYKKKYGPENVYDFTLGNPNVPPPSEFGDALLEVAAQSIPGKHGYMPNAGYPETR
EAIAAYLTAKFHIPLTADHIIMTCGAAGALNVTMKTILDPGDEVIIPTPYFVEYEFYVDNAGGISRLVPTKEDFNLDLEA
IRSAFTEKTRAVLINSPNNPTGRVYDEETIRGLAAIIEEKGRLYNRAVYLVSDEPYSDIVYDGIKVPFIMECCKNSIIAF
SYSKCLSVPGERIGYLALHPELADLQDVLSGMIFCNRILGYINAPALMQRVISHIQGVHVNVEEYKRKRDLLCEGLSACG
YSFAKPEGTFYLFVRSPIADDVTYVRALQLRRVLTTPGIGFGGPGYFRIAYCVDDAAITNAMPGFADTLKEYQNR

Sequences:

>Translated_395_residues
MPISNKIHGLITRSSWIRKMFEEGLIYKKKYGPENVYDFTLGNPNVPPPSEFGDALLEVAAQSIPGKHGYMPNAGYPETR
EAIAAYLTAKFHIPLTADHIIMTCGAAGALNVTMKTILDPGDEVIIPTPYFVEYEFYVDNAGGISRLVPTKEDFNLDLEA
IRSAFTEKTRAVLINSPNNPTGRVYDEETIRGLAAIIEEKGRLYNRAVYLVSDEPYSDIVYDGIKVPFIMECCKNSIIAF
SYSKCLSVPGERIGYLALHPELADLQDVLSGMIFCNRILGYINAPALMQRVISHIQGVHVNVEEYKRKRDLLCEGLSACG
YSFAKPEGTFYLFVRSPIADDVTYVRALQLRRVLTTPGIGFGGPGYFRIAYCVDDAAITNAMPGFADTLKEYQNR
>Mature_394_residues
PISNKIHGLITRSSWIRKMFEEGLIYKKKYGPENVYDFTLGNPNVPPPSEFGDALLEVAAQSIPGKHGYMPNAGYPETRE
AIAAYLTAKFHIPLTADHIIMTCGAAGALNVTMKTILDPGDEVIIPTPYFVEYEFYVDNAGGISRLVPTKEDFNLDLEAI
RSAFTEKTRAVLINSPNNPTGRVYDEETIRGLAAIIEEKGRLYNRAVYLVSDEPYSDIVYDGIKVPFIMECCKNSIIAFS
YSKCLSVPGERIGYLALHPELADLQDVLSGMIFCNRILGYINAPALMQRVISHIQGVHVNVEEYKRKRDLLCEGLSACGY
SFAKPEGTFYLFVRSPIADDVTYVRALQLRRVLTTPGIGFGGPGYFRIAYCVDDAAITNAMPGFADTLKEYQNR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=328, Percent_Identity=26.8292682926829, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4507369, Length=375, Percent_Identity=24.5333333333333, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI56713254, Length=328, Percent_Identity=26.8292682926829, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI95147551, Length=326, Percent_Identity=25.7668711656442, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI169881279, Length=326, Percent_Identity=25.7668711656442, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI1788722, Length=369, Percent_Identity=29.2682926829268, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1788627, Length=376, Percent_Identity=27.9255319148936, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786816, Length=323, Percent_Identity=25.3869969040248, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787710, Length=189, Percent_Identity=31.2169312169312, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=367, Percent_Identity=26.158038147139, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=345, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71994472, Length=227, Percent_Identity=23.7885462555066, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=227, Percent_Identity=23.7885462555066, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=379, Percent_Identity=23.7467018469657, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28573069, Length=345, Percent_Identity=28.9855072463768, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24646114, Length=345, Percent_Identity=28.9855072463768, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI28573067, Length=345, Percent_Identity=28.9855072463768, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI28573065, Length=345, Percent_Identity=28.9855072463768, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI18859735, Length=405, Percent_Identity=27.6543209876543, Blast_Score=98, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43920; Mature: 43789

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPISNKIHGLITRSSWIRKMFEEGLIYKKKYGPENVYDFTLGNPNVPPPSEFGDALLEVA
CCCCCCHHHEEEHHHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHH
AQSIPGKHGYMPNAGYPETREAIAAYLTAKFHIPLTADHIIMTCGAAGALNVTMKTILDP
HHHCCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCCCEEEECCCCCCHHEEHHHHCCC
GDEVIIPTPYFVEYEFYVDNAGGISRLVPTKEDFNLDLEAIRSAFTEKTRAVLINSPNNP
CCCEEECCCEEEEEEEEEECCCCCHHCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCC
TGRVYDEETIRGLAAIIEEKGRLYNRAVYLVSDEPYSDIVYDGIKVPFIMECCKNSIIAF
CCCEECHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHCCCCHHHHHHHHCCCEEEE
SYSKCLSVPGERIGYLALHPELADLQDVLSGMIFCNRILGYINAPALMQRVISHIQGVHV
EHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
NVEEYKRKRDLLCEGLSACGYSFAKPEGTFYLFVRSPIADDVTYVRALQLRRVLTTPGIG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
FGGPGYFRIAYCVDDAAITNAMPGFADTLKEYQNR
CCCCCCEEEEEEECCHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure 
PISNKIHGLITRSSWIRKMFEEGLIYKKKYGPENVYDFTLGNPNVPPPSEFGDALLEVA
CCCCCHHHEEEHHHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHH
AQSIPGKHGYMPNAGYPETREAIAAYLTAKFHIPLTADHIIMTCGAAGALNVTMKTILDP
HHHCCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCCCEEEECCCCCCHHEEHHHHCCC
GDEVIIPTPYFVEYEFYVDNAGGISRLVPTKEDFNLDLEAIRSAFTEKTRAVLINSPNNP
CCCEEECCCEEEEEEEEEECCCCCHHCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCC
TGRVYDEETIRGLAAIIEEKGRLYNRAVYLVSDEPYSDIVYDGIKVPFIMECCKNSIIAF
CCCEECHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHCCCCHHHHHHHHCCCEEEE
SYSKCLSVPGERIGYLALHPELADLQDVLSGMIFCNRILGYINAPALMQRVISHIQGVHV
EHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
NVEEYKRKRDLLCEGLSACGYSFAKPEGTFYLFVRSPIADDVTYVRALQLRRVLTTPGIG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
FGGPGYFRIAYCVDDAAITNAMPGFADTLKEYQNR
CCCCCCEEEEEEECCHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]