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The map label for this gene is erfK [H]

Identifier: 85859402

GI number: 85859402

Start: 1608206

End: 1609543

Strand: Direct

Name: erfK [H]

Synonym: SYN_02184

Alternate gene names: 85859402

Gene position: 1608206-1609543 (Clockwise)

Preceding gene: 85859401

Following gene: 85859403

Centisome position: 50.58

GC content: 47.46

Gene sequence:

>1338_bases
TTGGATCTTATTTGGCCCATGAACCGTAATTTTAAACCTGAAAACATATTCAAAAGACTTCGTCTTGTAACAGTTGCATT
TATCTTTATCTTAACTTCCCATGGATGCGCCGTACTGTACAACATTCCGGCTAAATCCCTGCCATCTTCAGGCGTTCCGG
ACGAAAGAATTGAACGAAATGATTTTTCCCTCACAAAAGACGCCGATGTCATCGGCCCGCTGATATACATGAGGCTTGAA
AAAGAGGATACACTTCCTGACATCGCAAGACACTTCAGTTTGGGAATCAATGAAATCAGTGCAGCGAATCCCGGTGTGGA
TATATGGGTACCTGAGGCTGGTGAACGGATCATGCTGCCACTGAGTTTTATCCTGCCGGATGCTCCCAGGAAAGGCATCG
TTATCAATCTGGCCGCCATGAGACTTTTTCAATTCAAAGGAGACGGCAAGTTCCTGACAGTGTCCACCTATCCGGTCGGG
ATCGGTTCTGAGGAACGACCGACACCTATGGGGCAAATGTATGTGCAGCGCAAAACAGCCCGTCCGACATGGCATGTGCC
TGCTTCAATTGCTGAAGATCATCGGAAAAAAGGAGATATTCTTCCCGCTAAAGTTCCTCCGGGGCCTGATAATCCCCTGG
GTGAATACGCACTGTATTTGAGTAATCCAAGTTATCTGATTCATGGAACGAATAAACCGGCCAGCATCGGTCTCAATGCA
ACCAATGGCTGCATAAGACTCTATCCGGAACACATAAAGAAACTGTATGAGAACACCCCGGTTAATACACGTGTATCCAT
CGTTAACCAGCCATATCTGGTCGGTCAGCGTAATGGTGTTGTTTACATGGAAGTCCATCCCTCATTGGAGAACTCTGCCG
CGGCTGAATTAAACAGGATATATGCAAAACTGAAAACTGCTGAAAGAAAATCGGCTCGGAAGATTGACTGGAAAAAGGTT
GGGGAAGTCCTGACCGAGGCACGGGGAATTCCTGTTCCCATATCTGGTCCCCCTCAGGAAAATGCCGACGGCGCTTTGAA
AACGATAGAAGTCGCCCATCCGGTAAAATTGTATGGCAGGCCGGAAATACCGGAGCTGAAGGTGGATTCGTGGTATGTCA
TGGCTGCTGACCAGAGCGATCGAACAAACGCGATGAGGATCGCTGCCATCATAAACCACCAGGGGCCGCAAATCCCGGCA
AGGATTTTATCAAAGGGCAAAAGCTATCGTGTCATTGCCGGTCCTTTCAATAACCTCACTGATGCGAGAGATGCAGTCAA
ACGTTTGAAAATCGATTTGGACATCAAAGGCATTTTAATTGAACCTGCGGGCAAGTGA

Upstream 100 bases:

>100_bases
CCGTTACGAATGAAGAGATAGAGGAAATTGCCCGTTTAGTGCGAAATGGTACAATTGTTCACATTTTGCCATAAAATGCC
TCAATACCATATCACAATAA

Downstream 100 bases:

>100_bases
TAGTTGATGACGTTTTTTCTGTTCATCGTTGCAATTTAAATAATACAGGAATACAATAACATGCAGGGGCGTGAGATAAT
TGTGGCAAAATTACATAGAA

Product: erfK/srfK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MDLIWPMNRNFKPENIFKRLRLVTVAFIFILTSHGCAVLYNIPAKSLPSSGVPDERIERNDFSLTKDADVIGPLIYMRLE
KEDTLPDIARHFSLGINEISAANPGVDIWVPEAGERIMLPLSFILPDAPRKGIVINLAAMRLFQFKGDGKFLTVSTYPVG
IGSEERPTPMGQMYVQRKTARPTWHVPASIAEDHRKKGDILPAKVPPGPDNPLGEYALYLSNPSYLIHGTNKPASIGLNA
TNGCIRLYPEHIKKLYENTPVNTRVSIVNQPYLVGQRNGVVYMEVHPSLENSAAAELNRIYAKLKTAERKSARKIDWKKV
GEVLTEARGIPVPISGPPQENADGALKTIEVAHPVKLYGRPEIPELKVDSWYVMAADQSDRTNAMRIAAIINHQGPQIPA
RILSKGKSYRVIAGPFNNLTDARDAVKRLKIDLDIKGILIEPAGK

Sequences:

>Translated_445_residues
MDLIWPMNRNFKPENIFKRLRLVTVAFIFILTSHGCAVLYNIPAKSLPSSGVPDERIERNDFSLTKDADVIGPLIYMRLE
KEDTLPDIARHFSLGINEISAANPGVDIWVPEAGERIMLPLSFILPDAPRKGIVINLAAMRLFQFKGDGKFLTVSTYPVG
IGSEERPTPMGQMYVQRKTARPTWHVPASIAEDHRKKGDILPAKVPPGPDNPLGEYALYLSNPSYLIHGTNKPASIGLNA
TNGCIRLYPEHIKKLYENTPVNTRVSIVNQPYLVGQRNGVVYMEVHPSLENSAAAELNRIYAKLKTAERKSARKIDWKKV
GEVLTEARGIPVPISGPPQENADGALKTIEVAHPVKLYGRPEIPELKVDSWYVMAADQSDRTNAMRIAAIINHQGPQIPA
RILSKGKSYRVIAGPFNNLTDARDAVKRLKIDLDIKGILIEPAGK
>Mature_445_residues
MDLIWPMNRNFKPENIFKRLRLVTVAFIFILTSHGCAVLYNIPAKSLPSSGVPDERIERNDFSLTKDADVIGPLIYMRLE
KEDTLPDIARHFSLGINEISAANPGVDIWVPEAGERIMLPLSFILPDAPRKGIVINLAAMRLFQFKGDGKFLTVSTYPVG
IGSEERPTPMGQMYVQRKTARPTWHVPASIAEDHRKKGDILPAKVPPGPDNPLGEYALYLSNPSYLIHGTNKPASIGLNA
TNGCIRLYPEHIKKLYENTPVNTRVSIVNQPYLVGQRNGVVYMEVHPSLENSAAAELNRIYAKLKTAERKSARKIDWKKV
GEVLTEARGIPVPISGPPQENADGALKTIEVAHPVKLYGRPEIPELKVDSWYVMAADQSDRTNAMRIAAIINHQGPQIPA
RILSKGKSYRVIAGPFNNLTDARDAVKRLKIDLDIKGILIEPAGK

Specific function: Responsible, at least in part, for anchoring of the major outer membrane lipoprotein (Lpp, also known as the Braun lipoprotein) to the peptidoglycan via a meso-diaminopimelyl-L-Lys- bond on the terminal residue of Lpp [H]

COG id: COG1376

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YkuD family [H]

Homologues:

Organism=Escherichia coli, GI1788299, Length=320, Percent_Identity=34.6875, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1787040, Length=210, Percent_Identity=42.8571428571429, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI1787356, Length=258, Percent_Identity=37.5968992248062, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1787968, Length=266, Percent_Identity=37.218045112782, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005490 [H]

Pfam domain/function: PF03734 YkuD [H]

EC number: NA

Molecular weight: Translated: 49363; Mature: 49363

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLIWPMNRNFKPENIFKRLRLVTVAFIFILTSHGCAVLYNIPAKSLPSSGVPDERIERN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHCCC
DFSLTKDADVIGPLIYMRLEKEDTLPDIARHFSLGINEISAANPGVDIWVPEAGERIMLP
CCCCCCCCHHHCCEEEEEECCCCCHHHHHHHHHCCCHHHCCCCCCCEEEECCCCCEEEEE
LSFILPDAPRKGIVINLAAMRLFQFKGDGKFLTVSTYPVGIGSEERPTPMGQMYVQRKTA
EHHHCCCCCCCCEEEEEEHEEEEEECCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCC
RPTWHVPASIAEDHRKKGDILPAKVPPGPDNPLGEYALYLSNPSYLIHGTNKPASIGLNA
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCEEECCC
TNGCIRLYPEHIKKLYENTPVNTRVSIVNQPYLVGQRNGVVYMEVHPSLENSAAAELNRI
CCCEEEECHHHHHHHHHCCCCCEEEEEECCCEEEECCCCEEEEEECCCCCCHHHHHHHHH
YAKLKTAERKSARKIDWKKVGEVLTEARGIPVPISGPPQENADGALKTIEVAHPVKLYGR
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCEEECCC
PEIPELKVDSWYVMAADQSDRTNAMRIAAIINHQGPQIPARILSKGKSYRVIAGPFNNLT
CCCCCEECCCEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCEEEEECCCCCCH
DARDAVKRLKIDLDIKGILIEPAGK
HHHHHHHHEEEEEEEEEEEECCCCC
>Mature Secondary Structure
MDLIWPMNRNFKPENIFKRLRLVTVAFIFILTSHGCAVLYNIPAKSLPSSGVPDERIERN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHCCC
DFSLTKDADVIGPLIYMRLEKEDTLPDIARHFSLGINEISAANPGVDIWVPEAGERIMLP
CCCCCCCCHHHCCEEEEEECCCCCHHHHHHHHHCCCHHHCCCCCCCEEEECCCCCEEEEE
LSFILPDAPRKGIVINLAAMRLFQFKGDGKFLTVSTYPVGIGSEERPTPMGQMYVQRKTA
EHHHCCCCCCCCEEEEEEHEEEEEECCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCC
RPTWHVPASIAEDHRKKGDILPAKVPPGPDNPLGEYALYLSNPSYLIHGTNKPASIGLNA
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCEEECCC
TNGCIRLYPEHIKKLYENTPVNTRVSIVNQPYLVGQRNGVVYMEVHPSLENSAAAELNRI
CCCEEEECHHHHHHHHHCCCCCEEEEEECCCEEEECCCCEEEEEECCCCCCHHHHHHHHH
YAKLKTAERKSARKIDWKKVGEVLTEARGIPVPISGPPQENADGALKTIEVAHPVKLYGR
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCEEECCC
PEIPELKVDSWYVMAADQSDRTNAMRIAAIINHQGPQIPARILSKGKSYRVIAGPFNNLT
CCCCCEECCCEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCEEEEECCCCCCH
DARDAVKRLKIDLDIKGILIEPAGK
HHHHHHHHEEEEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592411; 9097040; 9278503; 9298646 [H]