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The map label for this gene is kdsC [H]

Identifier: 85859054

GI number: 85859054

Start: 1228069

End: 1228620

Strand: Direct

Name: kdsC [H]

Synonym: SYN_00949

Alternate gene names: 85859054

Gene position: 1228069-1228620 (Clockwise)

Preceding gene: 85859053

Following gene: 85859055

Centisome position: 38.63

GC content: 51.99

Gene sequence:

>552_bases
ATGAGGGTGGTGAATGTGATCAAGGATGAAGCGGTAAAAAGCAGGATCAGGAAGATCCGTCTTCTGATGCTGGACGTGGA
TGGCGTTCTGACAGACGGGCGCATCATCATCGATGATGCGGGACTGGAAAGCAAATTTTTTGATGTCAGGGATGGCCATG
GCCTCAAACTGATCATGCGTTGCGGTCTTGATGTCGTTCTGTTGACCGGCCGCTCTTCGGCCGTGGTAACCCATCGCGCC
AGGGATCTGGGAATCCGGGAAGTTTTTCAGGGGATATTAAACAAATTGGAATTCTTTCAGCAGTTTATTGAGAAAAGGGA
AATTCGTCCGGAGGAGGTCGCCTATGTCGGGGATGACATGGTGGATATTCCCATTCTCAAGAGAGTCGGTTTTTCCGCTG
CCGTGAAGGATGCCGTCGAAGAAGTCAGGGAAATCGTGGATCATGTCACGGAAAGACCGGGCGGACGAGGCGCCGTTCGG
GAGCTATGCGAACTGATCCTCAAGGTTCAGGGGAGATGGGACGAGGTTACGCGGAAATACGAATTAGGCTGA

Upstream 100 bases:

>100_bases
CTGAGCTCCTGAGCACGGTGAAATCCATCGACCGGCTGGTAAAAAACAGGGCGGACGGCATTTTTTAACGATATCGGCTT
ATGCCGGCAGCTTCGCTCAA

Downstream 100 bases:

>100_bases
ATTCATTAATAGAATTCGATTCATGTTTGGTCTTTACTTGTCCTGAAACGGGTGATATACAACAGCAAAAACAGGAAAAG
GTTGAAAAGACTTATAACAA

Product: 3-deoxy-manno-octulosonate-8-phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MRVVNVIKDEAVKSRIRKIRLLMLDVDGVLTDGRIIIDDAGLESKFFDVRDGHGLKLIMRCGLDVVLLTGRSSAVVTHRA
RDLGIREVFQGILNKLEFFQQFIEKREIRPEEVAYVGDDMVDIPILKRVGFSAAVKDAVEEVREIVDHVTERPGGRGAVR
ELCELILKVQGRWDEVTRKYELG

Sequences:

>Translated_183_residues
MRVVNVIKDEAVKSRIRKIRLLMLDVDGVLTDGRIIIDDAGLESKFFDVRDGHGLKLIMRCGLDVVLLTGRSSAVVTHRA
RDLGIREVFQGILNKLEFFQQFIEKREIRPEEVAYVGDDMVDIPILKRVGFSAAVKDAVEEVREIVDHVTERPGGRGAVR
ELCELILKVQGRWDEVTRKYELG
>Mature_183_residues
MRVVNVIKDEAVKSRIRKIRLLMLDVDGVLTDGRIIIDDAGLESKFFDVRDGHGLKLIMRCGLDVVLLTGRSSAVVTHRA
RDLGIREVFQGILNKLEFFQQFIEKREIRPEEVAYVGDDMVDIPILKRVGFSAAVKDAVEEVREIVDHVTERPGGRGAVR
ELCELILKVQGRWDEVTRKYELG

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=156, Percent_Identity=32.6923076923077, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI2367202, Length=165, Percent_Identity=47.2727272727273, Blast_Score=154, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 20784; Mature: 20784

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVNVIKDEAVKSRIRKIRLLMLDVDGVLTDGRIIIDDAGLESKFFDVRDGHGLKLIMR
CCHHHHHHHHHHHHHHHHHHHHEEECCCEEECCEEEEECCCCCCCCCCCCCCCCHHHHHH
CGLDVVLLTGRSSAVVTHRARDLGIREVFQGILNKLEFFQQFIEKREIRPEEVAYVGDDM
CCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCC
VDIPILKRVGFSAAVKDAVEEVREIVDHVTERPGGRGAVRELCELILKVQGRWDEVTRKY
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
ELG
CCC
>Mature Secondary Structure
MRVVNVIKDEAVKSRIRKIRLLMLDVDGVLTDGRIIIDDAGLESKFFDVRDGHGLKLIMR
CCHHHHHHHHHHHHHHHHHHHHEEECCCEEECCEEEEECCCCCCCCCCCCCCCCHHHHHH
CGLDVVLLTGRSSAVVTHRARDLGIREVFQGILNKLEFFQQFIEKREIRPEEVAYVGDDM
CCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCC
VDIPILKRVGFSAAVKDAVEEVREIVDHVTERPGGRGAVRELCELILKVQGRWDEVTRKY
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
ELG
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]