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The map label for this gene is zraS [C]

Identifier: 85858961

GI number: 85858961

Start: 1142901

End: 1144850

Strand: Direct

Name: zraS [C]

Synonym: SYN_00568

Alternate gene names: 85858961

Gene position: 1142901-1144850 (Clockwise)

Preceding gene: 85858959

Following gene: 85858962

Centisome position: 35.95

GC content: 53.59

Gene sequence:

>1950_bases
TTGGAAATCTTCGAACAATTTCCTCTTGGGGTGTATGTCCATTTTTTTCAACATAAAGTACGCATAAACCGGATGAACCT
TTTTTATTCTCTCCGCTGGAAGAGAATGCTCGGTTATACAGAAAGTGAAGTTGGAAACACCCCTGACGAGTGGGACAAAC
GTGTCCATCCCGAGGACAGGAAACGTTGCCAGGAAGTGCTGGAAGCGCATTTAAGCGGAAAAACGCCGGTTTATGAAAGT
GAATATCGCCTTCTATGCAAGAACGGCACTTATAAATGGATTATGGATCGCGGGACAGTCATTAATCGGACGGCAGACGG
GAAACCGCTACGCGTTATTGGAACGCATGCAGACATCACCAGGCGCAGACTGATGGAGGATGAATTGCGGGAATCGAGGC
AGAGGCTTGCCGACATCATCAACTTTCTTCCCGACGCAACCCTGGTCATCGACAGGGAAAGCCGGGTCATTTCCTGGAAT
CAGGCGATAGAAAAAATGACGGGGATCAGCGCGGAAGAAATGCTCGGCAAGGGCAACTACGAGTATGCCCTTCCTTTTTA
CGGGGAAAGAAGGCCGATTCTCATCGATCACGCTCTTCGTCCGGATATGCAGGCGAAAAAACAATACACGGCCTTTTACA
GAGCGGGAGAGATTCTTTTCGGGCAATCCTGTGTGTCCGCACTTCCTTCCGGCGAACTCCATCTCTCCGCATCGGCATCT
GTTCTGCGGGATTCCCGGGGAGAGATCATTGCCGCCATTGAATGCATCCGGGATAATACCGAACTGAAAAAACTGCAGGA
CCGTCTGAACCGCGCCGAAAAGATGGAAGGGCTGGGAAGGCTGGCCGGAGGCGTAGCGCATGATCTCAATAATGTCCTGG
GGGTCCTGGTGGGATATTCGGAACTGCTTGCGGAAACCGTTCCCGGTGACAGCCCCTTGAAAAGGTATGCGAAAAACATC
CTGCAATCCGGGATGAGGGGGGCGGCGATCGTTCAGGATCTTTTGACGCTGGCCAGGAGAGGGGTGGTCGTATCAGAAGT
GATCAATCTGAACCAGGTGATTGCCGATTCCATCAAAACGCCGGAATATGAAATGCTGAAATTCGATCATCCGGATGTGC
GGATTCGCACCCATCTGGCGGAGGGACTCCTGAATATCAAGGGTTCCCCCATCCATTTAAGCAAAACGGTGATGAATCTG
ATTGTCAACGCCGCGGAGGCTGTCTCCGGTTGCGGCGACGTGACAATACGGACGGAGAATCGTTACCTGGACATGCCTGT
CCGGGGGTACGGCTCGATCCAGGAGGGGGATTACGCCGTCCTGTCCATATCGGACACGGGCAGCGGCATTTCTGCGGACG
ATCTGGACAAGATATTTGAACCCTTCTACACCAAAAAAGTCATGGGGAAAAGCGGGACGGGGCTGGGGCTGGCCGTTGTC
TGGGGGACCGTTAAGGATCATAACGGCTACATCGACGTACATAGTGAAGAGGGAAAAGGGACGACCTTCGCAATTTATTT
TCCCGTGACCAGCGAGGGAAGAACGGAAGCGGGCAAGGTGATACCCCCTGAATCCTATGCCGGCGGGGGTGAGTCGATTC
TGGTGGTGGATGATATTCCCGAACAGAGGGAAATGGCGCTCAGCATGCTCAAAAGGCTCGGGTATCGGGTTGATGCGGTT
CCCGGCGGTGAAGCGGCGGTTGATTATCTCCGCTCCCAGGCGATGGATCTTGTGGTGCTGGACATGATCATGCCCCCAGG
TATGGATGGTCTGGAAACTTATGAGCGGATTCTGGAAATCAACCCGGCGCAGAAGGCGATCATCGTCAGCGGGTTTTCCC
GGACGGAACGGGTGGAAAAAGCGCAGAAACTCGGGGCCGGAGCTTACGTCCGGAAACCCTATATCCTGGAAAACCTCGGG
CTGGCGGTTCGGAAGGAACTCGACCGGTGA

Upstream 100 bases:

>100_bases
CGTGATACTTCTTCCTTCGTATCGCGTCCTAACATAATCGTAGCCGACGAGGCTGAATCCGTGGTAAAGAAAACTCGTGG
ACATGCTTCCCCTCCGTTAA

Downstream 100 bases:

>100_bases
AGATCAAATCAAAAGGAAAGTCATTAAGGTCATCTCTCAAAACTATGCCGGAAGTCATTTATCATGTATAATGACGCGGT
CAATGTATCCTGCTCATTGA

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 649; Mature: 649

Protein sequence:

>649_residues
MEIFEQFPLGVYVHFFQHKVRINRMNLFYSLRWKRMLGYTESEVGNTPDEWDKRVHPEDRKRCQEVLEAHLSGKTPVYES
EYRLLCKNGTYKWIMDRGTVINRTADGKPLRVIGTHADITRRRLMEDELRESRQRLADIINFLPDATLVIDRESRVISWN
QAIEKMTGISAEEMLGKGNYEYALPFYGERRPILIDHALRPDMQAKKQYTAFYRAGEILFGQSCVSALPSGELHLSASAS
VLRDSRGEIIAAIECIRDNTELKKLQDRLNRAEKMEGLGRLAGGVAHDLNNVLGVLVGYSELLAETVPGDSPLKRYAKNI
LQSGMRGAAIVQDLLTLARRGVVVSEVINLNQVIADSIKTPEYEMLKFDHPDVRIRTHLAEGLLNIKGSPIHLSKTVMNL
IVNAAEAVSGCGDVTIRTENRYLDMPVRGYGSIQEGDYAVLSISDTGSGISADDLDKIFEPFYTKKVMGKSGTGLGLAVV
WGTVKDHNGYIDVHSEEGKGTTFAIYFPVTSEGRTEAGKVIPPESYAGGGESILVVDDIPEQREMALSMLKRLGYRVDAV
PGGEAAVDYLRSQAMDLVVLDMIMPPGMDGLETYERILEINPAQKAIIVSGFSRTERVEKAQKLGAGAYVRKPYILENLG
LAVRKELDR

Sequences:

>Translated_649_residues
MEIFEQFPLGVYVHFFQHKVRINRMNLFYSLRWKRMLGYTESEVGNTPDEWDKRVHPEDRKRCQEVLEAHLSGKTPVYES
EYRLLCKNGTYKWIMDRGTVINRTADGKPLRVIGTHADITRRRLMEDELRESRQRLADIINFLPDATLVIDRESRVISWN
QAIEKMTGISAEEMLGKGNYEYALPFYGERRPILIDHALRPDMQAKKQYTAFYRAGEILFGQSCVSALPSGELHLSASAS
VLRDSRGEIIAAIECIRDNTELKKLQDRLNRAEKMEGLGRLAGGVAHDLNNVLGVLVGYSELLAETVPGDSPLKRYAKNI
LQSGMRGAAIVQDLLTLARRGVVVSEVINLNQVIADSIKTPEYEMLKFDHPDVRIRTHLAEGLLNIKGSPIHLSKTVMNL
IVNAAEAVSGCGDVTIRTENRYLDMPVRGYGSIQEGDYAVLSISDTGSGISADDLDKIFEPFYTKKVMGKSGTGLGLAVV
WGTVKDHNGYIDVHSEEGKGTTFAIYFPVTSEGRTEAGKVIPPESYAGGGESILVVDDIPEQREMALSMLKRLGYRVDAV
PGGEAAVDYLRSQAMDLVVLDMIMPPGMDGLETYERILEINPAQKAIIVSGFSRTERVEKAQKLGAGAYVRKPYILENLG
LAVRKELDR
>Mature_649_residues
MEIFEQFPLGVYVHFFQHKVRINRMNLFYSLRWKRMLGYTESEVGNTPDEWDKRVHPEDRKRCQEVLEAHLSGKTPVYES
EYRLLCKNGTYKWIMDRGTVINRTADGKPLRVIGTHADITRRRLMEDELRESRQRLADIINFLPDATLVIDRESRVISWN
QAIEKMTGISAEEMLGKGNYEYALPFYGERRPILIDHALRPDMQAKKQYTAFYRAGEILFGQSCVSALPSGELHLSASAS
VLRDSRGEIIAAIECIRDNTELKKLQDRLNRAEKMEGLGRLAGGVAHDLNNVLGVLVGYSELLAETVPGDSPLKRYAKNI
LQSGMRGAAIVQDLLTLARRGVVVSEVINLNQVIADSIKTPEYEMLKFDHPDVRIRTHLAEGLLNIKGSPIHLSKTVMNL
IVNAAEAVSGCGDVTIRTENRYLDMPVRGYGSIQEGDYAVLSISDTGSGISADDLDKIFEPFYTKKVMGKSGTGLGLAVV
WGTVKDHNGYIDVHSEEGKGTTFAIYFPVTSEGRTEAGKVIPPESYAGGGESILVVDDIPEQREMALSMLKRLGYRVDAV
PGGEAAVDYLRSQAMDLVVLDMIMPPGMDGLETYERILEINPAQKAIIVSGFSRTERVEKAQKLGAGAYVRKPYILENLG
LAVRKELDR

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=32.2448979591837, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788549, Length=398, Percent_Identity=28.391959798995, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI48994928, Length=408, Percent_Identity=28.921568627451, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788713, Length=566, Percent_Identity=23.8515901060071, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790300, Length=374, Percent_Identity=24.5989304812834, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1789808, Length=244, Percent_Identity=28.2786885245902, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786600, Length=245, Percent_Identity=24.4897959183673, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790861, Length=247, Percent_Identity=26.7206477732794, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790346, Length=241, Percent_Identity=24.4813278008299, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=115, Percent_Identity=35.6521739130435, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=319, Percent_Identity=24.7648902821317, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788381, Length=253, Percent_Identity=23.7154150197628, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI87081816, Length=250, Percent_Identity=24.4, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72460; Mature: 72460

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFEQFPLGVYVHFFQHKVRINRMNLFYSLRWKRMLGYTESEVGNTPDEWDKRVHPEDR
CCCHHHCCCHHHHHHHHHHHEEEEEEEEHHHHHHHHHCCCHHHCCCCCCHHHHCCCCHHH
KRCQEVLEAHLSGKTPVYESEYRLLCKNGTYKWIMDRGTVINRTADGKPLRVIGTHADIT
HHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEECCCEEEEECCCCCCEEEEECCHHHH
RRRLMEDELRESRQRLADIINFLPDATLVIDRESRVISWNQAIEKMTGISAEEMLGKGNY
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEHHHHHHHHHCCCHHHHHCCCCC
EYALPFYGERRPILIDHALRPDMQAKKQYTAFYRAGEILFGQSCVSALPSGELHLSASAS
EEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEECCHHHHHCCCCCEEEECCHH
VLRDSRGEIIAAIECIRDNTELKKLQDRLNRAEKMEGLGRLAGGVAHDLNNVLGVLVGYS
HHHCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLAETVPGDSPLKRYAKNILQSGMRGAAIVQDLLTLARRGVVVSEVINLNQVIADSIKT
HHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
PEYEMLKFDHPDVRIRTHLAEGLLNIKGSPIHLSKTVMNLIVNAAEAVSGCGDVTIRTEN
CCHHEEECCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCEEEEECC
RYLDMPVRGYGSIQEGDYAVLSISDTGSGISADDLDKIFEPFYTKKVMGKSGTGLGLAVV
EEEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
WGTVKDHNGYIDVHSEEGKGTTFAIYFPVTSEGRTEAGKVIPPESYAGGGESILVVDDIP
EEEEECCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCC
EQREMALSMLKRLGYRVDAVPGGEAAVDYLRSQAMDLVVLDMIMPPGMDGLETYERILEI
HHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
NPAQKAIIVSGFSRTERVEKAQKLGAGAYVRKPYILENLGLAVRKELDR
CCCCCEEEEECCHHHHHHHHHHHCCCCCEECCCHHHHHCCHHHHHHCCC
>Mature Secondary Structure
MEIFEQFPLGVYVHFFQHKVRINRMNLFYSLRWKRMLGYTESEVGNTPDEWDKRVHPEDR
CCCHHHCCCHHHHHHHHHHHEEEEEEEEHHHHHHHHHCCCHHHCCCCCCHHHHCCCCHHH
KRCQEVLEAHLSGKTPVYESEYRLLCKNGTYKWIMDRGTVINRTADGKPLRVIGTHADIT
HHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEECCCEEEEECCCCCCEEEEECCHHHH
RRRLMEDELRESRQRLADIINFLPDATLVIDRESRVISWNQAIEKMTGISAEEMLGKGNY
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEHHHHHHHHHCCCHHHHHCCCCC
EYALPFYGERRPILIDHALRPDMQAKKQYTAFYRAGEILFGQSCVSALPSGELHLSASAS
EEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEECCHHHHHCCCCCEEEECCHH
VLRDSRGEIIAAIECIRDNTELKKLQDRLNRAEKMEGLGRLAGGVAHDLNNVLGVLVGYS
HHHCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLAETVPGDSPLKRYAKNILQSGMRGAAIVQDLLTLARRGVVVSEVINLNQVIADSIKT
HHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
PEYEMLKFDHPDVRIRTHLAEGLLNIKGSPIHLSKTVMNLIVNAAEAVSGCGDVTIRTEN
CCHHEEECCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCEEEEECC
RYLDMPVRGYGSIQEGDYAVLSISDTGSGISADDLDKIFEPFYTKKVMGKSGTGLGLAVV
EEEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
WGTVKDHNGYIDVHSEEGKGTTFAIYFPVTSEGRTEAGKVIPPESYAGGGESILVVDDIP
EEEEECCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCC
EQREMALSMLKRLGYRVDAVPGGEAAVDYLRSQAMDLVVLDMIMPPGMDGLETYERILEI
HHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
NPAQKAIIVSGFSRTERVEKAQKLGAGAYVRKPYILENLGLAVRKELDR
CCCCCEEEEECCHHHHHHHHHHHCCCCCEECCCHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA