Click here to switch to the map view.

The map label for this gene is yjgC [H]

Identifier: 85858923

GI number: 85858923

Start: 1102748

End: 1103806

Strand: Direct

Name: yjgC [H]

Synonym: SYN_02137

Alternate gene names: 85858923

Gene position: 1102748-1103806 (Clockwise)

Preceding gene: 85858922

Following gene: 85858924

Centisome position: 34.69

GC content: 57.41

Gene sequence:

>1059_bases
ATGCAACAGATCAAGCTCAGTATCGACGGGAAGGAGGTTACCGGGACAGCGGGCCAGACCATACTGGAAATTGCGCTTGC
CAGCGGCATTGACATTCCCACCCTGTGTTATCATCCCAAGATCAGCAAGACCGGTGCGTGCCGTCTCTGTCTGGTTCGGG
TCAACAACGGCATGCTGAAGACATCCTGCACCGAACCGGCTATGGAAGGCATGTCGATTATTACGGAAGATGAGGAAATC
CGGGGAATCCGCAAGGGAATCCTGGAACTGCTCCTCTCCGAAGGCGATCACAACTGCCTTTACTGCGACGCCAACGGCGC
CTGTGAACTGCAAACCCTGGTAAACCGCTACGGCATTGAGCCGGTGAGCAGCGATTTTCCCCGTAATGTTCGGGTCATCG
ATTACGAGTCCAGCGAAGGGCTGAAGCGGAACGAAAACCGCTGTGTCCTCTGTGGGCGGTGCGTCAAGGCCTGCGGCGAG
ATTCAGATGTCCAATGTCTGGCAGTTCACGGATCGGGGGAGCCATGCCCATCTGACCTCCGGGATGTTCCAGACCATCGG
CGATTCCAGTTGCGTGAAATGCGGGACCTGCGTGCAGCTTTGTCCCACCGGCGCCCTGACCTTTCAGACGGTGCTCGGCA
GGGGGCAGAACTGGGAGCTGGAAAAGGAATCAAGCATCTGCATTTACTGCGGCGTGGGTTGCAAGATCGATTTCTGCAAG
AACAAGGCCGGTCAGCTTGTCAAGGCCCTCGGCCATGACGACGGTCCCAACAACGGCCATCTCTGCGTCAAGGGACGGTT
CGGGTTCGATTTCGTCCAGAGCCCCAAGAGACTGTCCAAACCCCTCATCCGGAAGAACGGGCAGCTCGAGGAAGCGAGCT
GGGATGAAGCCCTGGACCTGGTTGCCTCCAGATTCAAGGAAATCAAGGAGAAAAGCGGGCCGGACGCCCTGGCGGCCCTT
TCTTCCGCTAAATGCACCAACGAAGATAATTACCTCATGCAGAAATTCATGCGCGCGGCGATCGGCACCAACAATGTGGA
TCACTGCGCCCGGCTCTGA

Upstream 100 bases:

>100_bases
GGAAAAATGAGGGATGTGTCCAATTGCAAACGGATAACCATCCGGTACACTTATAACAGGCGCTTAAAGGAAACGCCATA
ATTCACGAAGGAGTTACCTT

Downstream 100 bases:

>100_bases
CACAGCTCCACCGTCGCCGGTCTGGCGGCAGTGTTCGGCTCCGGAGCCATGACGAATTCCATTCGGGAAGTTCCCGTCAG
TGAAGGCTATCTCCTGATCG

Product: formate dehydrogenase iron-sulfur subunit

Products: CO2; NADH

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MQQIKLSIDGKEVTGTAGQTILEIALASGIDIPTLCYHPKISKTGACRLCLVRVNNGMLKTSCTEPAMEGMSIITEDEEI
RGIRKGILELLLSEGDHNCLYCDANGACELQTLVNRYGIEPVSSDFPRNVRVIDYESSEGLKRNENRCVLCGRCVKACGE
IQMSNVWQFTDRGSHAHLTSGMFQTIGDSSCVKCGTCVQLCPTGALTFQTVLGRGQNWELEKESSICIYCGVGCKIDFCK
NKAGQLVKALGHDDGPNNGHLCVKGRFGFDFVQSPKRLSKPLIRKNGQLEEASWDEALDLVASRFKEIKEKSGPDALAAL
SSAKCTNEDNYLMQKFMRAAIGTNNVDHCARL

Sequences:

>Translated_352_residues
MQQIKLSIDGKEVTGTAGQTILEIALASGIDIPTLCYHPKISKTGACRLCLVRVNNGMLKTSCTEPAMEGMSIITEDEEI
RGIRKGILELLLSEGDHNCLYCDANGACELQTLVNRYGIEPVSSDFPRNVRVIDYESSEGLKRNENRCVLCGRCVKACGE
IQMSNVWQFTDRGSHAHLTSGMFQTIGDSSCVKCGTCVQLCPTGALTFQTVLGRGQNWELEKESSICIYCGVGCKIDFCK
NKAGQLVKALGHDDGPNNGHLCVKGRFGFDFVQSPKRLSKPLIRKNGQLEEASWDEALDLVASRFKEIKEKSGPDALAAL
SSAKCTNEDNYLMQKFMRAAIGTNNVDHCARL
>Mature_352_residues
MQQIKLSIDGKEVTGTAGQTILEIALASGIDIPTLCYHPKISKTGACRLCLVRVNNGMLKTSCTEPAMEGMSIITEDEEI
RGIRKGILELLLSEGDHNCLYCDANGACELQTLVNRYGIEPVSSDFPRNVRVIDYESSEGLKRNENRCVLCGRCVKACGE
IQMSNVWQFTDRGSHAHLTSGMFQTIGDSSCVKCGTCVQLCPTGALTFQTVLGRGQNWELEKESSICIYCGVGCKIDFCK
NKAGQLVKALGHDDGPNNGHLCVKGRFGFDFVQSPKRLSKPLIRKNGQLEEASWDEALDLVASRFKEIKEKSGPDALAAL
SSAKCTNEDNYLMQKFMRAAIGTNNVDHCARL

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG3383

COG function: function code R; Uncharacterized anaerobic dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=313, Percent_Identity=29.3929712460064, Blast_Score=138, Evalue=8e-33,
Organism=Escherichia coli, GI145693161, Length=352, Percent_Identity=27.5568181818182, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI3868721, Length=140, Percent_Identity=47.8571428571429, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788534, Length=145, Percent_Identity=29.6551724137931, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI3868720, Length=147, Percent_Identity=34.6938775510204, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17565758, Length=311, Percent_Identity=29.5819935691318, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI32566231, Length=311, Percent_Identity=29.5819935691318, Blast_Score=144, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI193209088, Length=252, Percent_Identity=28.1746031746032, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24640559, Length=306, Percent_Identity=29.4117647058824, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24640557, Length=306, Percent_Identity=29.4117647058824, Blast_Score=126, Evalue=2e-29,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR019574 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: 1.2.1.2

Molecular weight: Translated: 38519; Mature: 38519

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
6.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQIKLSIDGKEVTGTAGQTILEIALASGIDIPTLCYHPKISKTGACRLCLVRVNNGMLK
CCEEEEEECCCEECCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEEEECCCEEE
TSCTEPAMEGMSIITEDEEIRGIRKGILELLLSEGDHNCLYCDANGACELQTLVNRYGIE
CCCCCHHHHCCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCC
PVSSDFPRNVRVIDYESSEGLKRNENRCVLCGRCVKACGEIQMSNVWQFTDRGSHAHLTS
CCCCCCCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHCCCCCCCEEEECCCCCCCHHHH
GMFQTIGDSSCVKCGTCVQLCPTGALTFQTVLGRGQNWELEKESSICIYCGVGCKIDFCK
HHHHHCCCCCHHECCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEHHH
NKAGQLVKALGHDDGPNNGHLCVKGRFGFDFVQSPKRLSKPLIRKNGQLEEASWDEALDL
CHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHH
VASRFKEIKEKSGPDALAALSSAKCTNEDNYLMQKFMRAAIGTNNVDHCARL
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure
MQQIKLSIDGKEVTGTAGQTILEIALASGIDIPTLCYHPKISKTGACRLCLVRVNNGMLK
CCEEEEEECCCEECCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEEEECCCEEE
TSCTEPAMEGMSIITEDEEIRGIRKGILELLLSEGDHNCLYCDANGACELQTLVNRYGIE
CCCCCHHHHCCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCC
PVSSDFPRNVRVIDYESSEGLKRNENRCVLCGRCVKACGEIQMSNVWQFTDRGSHAHLTS
CCCCCCCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHCCCCCCCEEEECCCCCCCHHHH
GMFQTIGDSSCVKCGTCVQLCPTGALTFQTVLGRGQNWELEKESSICIYCGVGCKIDFCK
HHHHHCCCCCHHECCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEHHH
NKAGQLVKALGHDDGPNNGHLCVKGRFGFDFVQSPKRLSKPLIRKNGQLEEASWDEALDL
CHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHH
VASRFKEIKEKSGPDALAALSSAKCTNEDNYLMQKFMRAAIGTNNVDHCARL
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]