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The map label for this gene is zupT [H]

Identifier: 85858917

GI number: 85858917

Start: 1096801

End: 1097706

Strand: Direct

Name: zupT [H]

Synonym: SYN_02130

Alternate gene names: 85858917

Gene position: 1096801-1097706 (Clockwise)

Preceding gene: 85858916

Following gene: 85858918

Centisome position: 34.5

GC content: 55.63

Gene sequence:

>906_bases
ATGCAGGAAGTATGGATCGCCTTTGGACTGACCGTGTTTGCGGGTATGGCCACCGGCATCGGGAGTGTGATCGCCTTTAC
TGCGAAGAGGACCGACTACCGTTTTCTTTCGATTGCTACCGGCTTTTCCGCGGGTGTCATGCTTTACGTCTCTTTCGTTG
AAATCTTTGCGAAGGGACTGGACGCTCTGACCGCCGCGTATGGTGATTACTGGGGACACTGGGCGAATGCCGCCGCGTTT
TTCTGCGGGGTGTTCCTGATTGGTCTGATCGACAGCCTGATCCCGGCGGAGGAGAATCCTCACGAGACGCACTCCGAAGA
GGAAACGGCGCCCCTTCATGATCCGACTGCCCCGATTTCCGATTGCCATGCAATCGCGGGTGAGGACAGGGCCAATTCAT
CGTCAAATTTGCAAGATAATCGCATCCGGCACCAGAAACTCATGAGGATGGGGCTGTTTACGGCGCTGGCAATTACAATC
CACAATTTTCCAGAAGGCTTTGCGACGTTTCTTGCCGCCCTTCATGATCCTGCCGTCGGCCTGGCCATCGCCGCAGCCCT
TGCACTGCACAACATCCCTGAAGGAATAAGCGTTTCTGTACCGATATTTTACGCTACCGGAAACCGGAAGAAGGCATTTG
TGTATTCGTCGCTCAGCGGTCTGGCCGAGCCTGTTGGCGCCGGGATCGCCTATCTTGCGATTCGTTTTTTTCTTGGCGAT
AACGTTGGAGGAATCCCTTCCCAAATCATGGGATTGCTCTTTGGTGGCGTGGCCGGCATCATGGTTTACATCAGCCTTGA
CGAGCTGCTGCCGACAAGCCGGGCTTATGGCAAGGGGCACGACAGCCTGATCGGCCTCGTGGCCGGGATGCTTGTGATGG
CCCTGAGCCTGTTGCTGATGAAGTGA

Upstream 100 bases:

>100_bases
CTCCGGTGGAGTTCCCATCGCAAAGACTGAAGCAGATTATCCTGTCTGTCCCGTGCATGTCGCCGCTTGTTTCAACCATT
AATCCACATGGAGATGCCGT

Downstream 100 bases:

>100_bases
TGGTAATGCGGGCGGCCAAATGCTTTTTCAGAAATGCGGTAAATTGCGGCAAAATCCGCTTGACAGGCCGGATCGCCCTC
CGTATCCTCAACGTGCGCAT

Product: zinc transporter ZupT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MQEVWIAFGLTVFAGMATGIGSVIAFTAKRTDYRFLSIATGFSAGVMLYVSFVEIFAKGLDALTAAYGDYWGHWANAAAF
FCGVFLIGLIDSLIPAEENPHETHSEEETAPLHDPTAPISDCHAIAGEDRANSSSNLQDNRIRHQKLMRMGLFTALAITI
HNFPEGFATFLAALHDPAVGLAIAAALALHNIPEGISVSVPIFYATGNRKKAFVYSSLSGLAEPVGAGIAYLAIRFFLGD
NVGGIPSQIMGLLFGGVAGIMVYISLDELLPTSRAYGKGHDSLIGLVAGMLVMALSLLLMK

Sequences:

>Translated_301_residues
MQEVWIAFGLTVFAGMATGIGSVIAFTAKRTDYRFLSIATGFSAGVMLYVSFVEIFAKGLDALTAAYGDYWGHWANAAAF
FCGVFLIGLIDSLIPAEENPHETHSEEETAPLHDPTAPISDCHAIAGEDRANSSSNLQDNRIRHQKLMRMGLFTALAITI
HNFPEGFATFLAALHDPAVGLAIAAALALHNIPEGISVSVPIFYATGNRKKAFVYSSLSGLAEPVGAGIAYLAIRFFLGD
NVGGIPSQIMGLLFGGVAGIMVYISLDELLPTSRAYGKGHDSLIGLVAGMLVMALSLLLMK
>Mature_301_residues
MQEVWIAFGLTVFAGMATGIGSVIAFTAKRTDYRFLSIATGFSAGVMLYVSFVEIFAKGLDALTAAYGDYWGHWANAAAF
FCGVFLIGLIDSLIPAEENPHETHSEEETAPLHDPTAPISDCHAIAGEDRANSSSNLQDNRIRHQKLMRMGLFTALAITI
HNFPEGFATFLAALHDPAVGLAIAAALALHNIPEGISVSVPIFYATGNRKKAFVYSSLSGLAEPVGAGIAYLAIRFFLGD
NVGGIPSQIMGLLFGGVAGIMVYISLDELLPTSRAYGKGHDSLIGLVAGMLVMALSLLLMK

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI229577422, Length=332, Percent_Identity=26.2048192771084, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI229577418, Length=325, Percent_Identity=25.8461538461538, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1789419, Length=297, Percent_Identity=30.976430976431, Blast_Score=120, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17507805, Length=304, Percent_Identity=26.6447368421053, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24652846, Length=325, Percent_Identity=24.3076923076923, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 31958; Mature: 31958

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEVWIAFGLTVFAGMATGIGSVIAFTAKRTDYRFLSIATGFSAGVMLYVSFVEIFAKGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
DALTAAYGDYWGHWANAAAFFCGVFLIGLIDSLIPAEENPHETHSEEETAPLHDPTAPIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
DCHAIAGEDRANSSSNLQDNRIRHQKLMRMGLFTALAITIHNFPEGFATFLAALHDPAVG
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHH
LAIAAALALHNIPEGISVSVPIFYATGNRKKAFVYSSLSGLAEPVGAGIAYLAIRFFLGD
HHHHHHHHHHCCCCCCEEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NVGGIPSQIMGLLFGGVAGIMVYISLDELLPTSRAYGKGHDSLIGLVAGMLVMALSLLLM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHC
K
C
>Mature Secondary Structure
MQEVWIAFGLTVFAGMATGIGSVIAFTAKRTDYRFLSIATGFSAGVMLYVSFVEIFAKGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
DALTAAYGDYWGHWANAAAFFCGVFLIGLIDSLIPAEENPHETHSEEETAPLHDPTAPIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
DCHAIAGEDRANSSSNLQDNRIRHQKLMRMGLFTALAITIHNFPEGFATFLAALHDPAVG
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHH
LAIAAALALHNIPEGISVSVPIFYATGNRKKAFVYSSLSGLAEPVGAGIAYLAIRFFLGD
HHHHHHHHHHCCCCCCEEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NVGGIPSQIMGLLFGGVAGIMVYISLDELLPTSRAYGKGHDSLIGLVAGMLVMALSLLLM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA