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The map label for this gene is hipA [C]

Identifier: 85858769

GI number: 85858769

Start: 959970

End: 961250

Strand: Direct

Name: hipA [C]

Synonym: SYN_02732

Alternate gene names: 85858769

Gene position: 959970-961250 (Clockwise)

Preceding gene: 85858768

Following gene: 85858770

Centisome position: 30.19

GC content: 52.85

Gene sequence:

>1281_bases
ATGTTTACATCGAATCAAGGAGCTGGCCGAATGAATAAAGAGGTCGGCATGGATAATCCTGGTCTGGATGTCTATCTCCG
GGATCAAAAAATCGGACGGCTCTGGCTGGATGATAAAAGACGCTTTGTGTTTCAATATGACAGCGAATGGACACATCAGA
AGGGTGCCGTTCCCTTGTCGCTGCACCTCCCTTTGAGAGAGGAGATATACCCTGATGATCTTGCCCGCCCTTTTTTTTCC
AATCTCCTGCCGGAGGCTGAAGTCAAACGGGCTATTGCCCAACGCCTGAGAATTTCTGAAAGTAATGACTTTGCCCTGTT
GAACAGTATCGGCGGGGAGTGCGCGGGGGCGGTATCCGTACTGCCCGCGGGCGTCGCTCCCGCCATGAAACCGGGCTATC
GGGAACTCAGCGAGGAAGAACTGCACCGGATTATCATCGAGCTTCCCCGAAGGCCGCTGCTTGCCGGTGTAGAAGGAATG
AGACTTTCGCTGGCCGGGGCGCAGAACAAGTTGCCTGTTTACATGGAAGACCACCGCATCTTCATCGCCACGGGAAATGC
ACCGAGCAGCCATATCCTGAAACCGCCGATCAGGGATCTGGAGGATACGGTGGGGAATGAAGCATTCTGCATGATACTCG
CGCAGAGACTGGGGTTGCAGGTTCCGGTGGTTACGATCCGCCGGGGTCTTGATCGGATTTTCATCATTGCGCGTTATGAC
CGCAGCCGAGACACGGATGGCCACATCGTGCGTCTGCACCAGGAAGACTTCTGCCAGGCCCTGGGGTTTCTCCCCGAACA
GAAATACGAAAATGAAGGCGGCCCGTCTTTAAAACAGTGTTTTACCCTGCTGCAGGAAAAAAGCATTCGTCCCGCCGCCG
ATCGCATGGCCCTTTTGCGATGGACGATCTTTAATTTACTGATCGGCAATGACGACGCTCATGCTAAGAATCTGGCCATG
ATTTTTACGGACCGGGGGCCGCGACTCGCGCCTTTTTACGATCTGATCTGCACTCAGGTCTATCCGGATTTGACGGAAAA
ACAAGCCATGAGGATAGGCGGTGAGAACCGGCCGTCCTGGATTCTGCAGAAACACTGGGACAGATTCAGCGAATCAACCG
CGATCAAGCCAAATCTTGTTTTGAAGACGTTAAAAGAAATGTCTGCCGCCATTGCCCTAGCGGCGCAAACACTATCGAGC
GAGTTCATAAAAAAATACGGAACGTGCACGATTATTGAGGAGATACTGGCTGTCATTGAGAAAAGGGCAGAGTCCGTCTG
A

Upstream 100 bases:

>100_bases
TTATGCGGTGTCGGGTACAGATTCATGTCCGATCTGGAAAACGGCAAAGCGACGGCGCAGGTTGGGAAGGTTCTGCAGGT
TCTGACGGCGCTGGGGCTCG

Downstream 100 bases:

>100_bases
AAAGATCACTTTGCATGCACGCACCGAAGCGATTTTTTGTCATCCTTGACCTTAAGCGTCACCTGATTGATCATATTCCC
GTATACAATCAGTATGACGA

Product: protein HipA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MFTSNQGAGRMNKEVGMDNPGLDVYLRDQKIGRLWLDDKRRFVFQYDSEWTHQKGAVPLSLHLPLREEIYPDDLARPFFS
NLLPEAEVKRAIAQRLRISESNDFALLNSIGGECAGAVSVLPAGVAPAMKPGYRELSEEELHRIIIELPRRPLLAGVEGM
RLSLAGAQNKLPVYMEDHRIFIATGNAPSSHILKPPIRDLEDTVGNEAFCMILAQRLGLQVPVVTIRRGLDRIFIIARYD
RSRDTDGHIVRLHQEDFCQALGFLPEQKYENEGGPSLKQCFTLLQEKSIRPAADRMALLRWTIFNLLIGNDDAHAKNLAM
IFTDRGPRLAPFYDLICTQVYPDLTEKQAMRIGGENRPSWILQKHWDRFSESTAIKPNLVLKTLKEMSAAIALAAQTLSS
EFIKKYGTCTIIEEILAVIEKRAESV

Sequences:

>Translated_426_residues
MFTSNQGAGRMNKEVGMDNPGLDVYLRDQKIGRLWLDDKRRFVFQYDSEWTHQKGAVPLSLHLPLREEIYPDDLARPFFS
NLLPEAEVKRAIAQRLRISESNDFALLNSIGGECAGAVSVLPAGVAPAMKPGYRELSEEELHRIIIELPRRPLLAGVEGM
RLSLAGAQNKLPVYMEDHRIFIATGNAPSSHILKPPIRDLEDTVGNEAFCMILAQRLGLQVPVVTIRRGLDRIFIIARYD
RSRDTDGHIVRLHQEDFCQALGFLPEQKYENEGGPSLKQCFTLLQEKSIRPAADRMALLRWTIFNLLIGNDDAHAKNLAM
IFTDRGPRLAPFYDLICTQVYPDLTEKQAMRIGGENRPSWILQKHWDRFSESTAIKPNLVLKTLKEMSAAIALAAQTLSS
EFIKKYGTCTIIEEILAVIEKRAESV
>Mature_426_residues
MFTSNQGAGRMNKEVGMDNPGLDVYLRDQKIGRLWLDDKRRFVFQYDSEWTHQKGAVPLSLHLPLREEIYPDDLARPFFS
NLLPEAEVKRAIAQRLRISESNDFALLNSIGGECAGAVSVLPAGVAPAMKPGYRELSEEELHRIIIELPRRPLLAGVEGM
RLSLAGAQNKLPVYMEDHRIFIATGNAPSSHILKPPIRDLEDTVGNEAFCMILAQRLGLQVPVVTIRRGLDRIFIIARYD
RSRDTDGHIVRLHQEDFCQALGFLPEQKYENEGGPSLKQCFTLLQEKSIRPAADRMALLRWTIFNLLIGNDDAHAKNLAM
IFTDRGPRLAPFYDLICTQVYPDLTEKQAMRIGGENRPSWILQKHWDRFSESTAIKPNLVLKTLKEMSAAIALAAQTLSS
EFIKKYGTCTIIEEILAVIEKRAESV

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4dM [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=337, Percent_Identity=32.9376854599407, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 48105; Mature: 48105

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTSNQGAGRMNKEVGMDNPGLDVYLRDQKIGRLWLDDKRRFVFQYDSEWTHQKGAVPLS
CCCCCCCCCCCCHHCCCCCCCCEEEECCCCCCCEEECCCCEEEEEECCCCCCCCCCEEEE
LHLPLREEIYPDDLARPFFSNLLPEAEVKRAIAQRLRISESNDFALLNSIGGECAGAVSV
EECCHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEHHHCCCHHHHHHHH
LPAGVAPAMKPGYRELSEEELHRIIIELPRRPLLAGVEGMRLSLAGAQNKLPVYMEDHRI
HCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCHHHHCCCCCEEEECCCCCCCCEEEECCEE
FIATGNAPSSHILKPPIRDLEDTVGNEAFCMILAQRLGLQVPVVTIRRGLDRIFIIARYD
EEEECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEEEEC
RSRDTDGHIVRLHQEDFCQALGFLPEQKYENEGGPSLKQCFTLLQEKSIRPAADRMALLR
CCCCCCCCEEEECHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
WTIFNLLIGNDDAHAKNLAMIFTDRGPRLAPFYDLICTQVYPDLTEKQAMRIGGENRPSW
HHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCH
ILQKHWDRFSESTAIKPNLVLKTLKEMSAAIALAAQTLSSEFIKKYGTCTIIEEILAVIE
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KRAESV
HHHCCC
>Mature Secondary Structure
MFTSNQGAGRMNKEVGMDNPGLDVYLRDQKIGRLWLDDKRRFVFQYDSEWTHQKGAVPLS
CCCCCCCCCCCCHHCCCCCCCCEEEECCCCCCCEEECCCCEEEEEECCCCCCCCCCEEEE
LHLPLREEIYPDDLARPFFSNLLPEAEVKRAIAQRLRISESNDFALLNSIGGECAGAVSV
EECCHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEHHHCCCHHHHHHHH
LPAGVAPAMKPGYRELSEEELHRIIIELPRRPLLAGVEGMRLSLAGAQNKLPVYMEDHRI
HCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCHHHHCCCCCEEEECCCCCCCCEEEECCEE
FIATGNAPSSHILKPPIRDLEDTVGNEAFCMILAQRLGLQVPVVTIRRGLDRIFIIARYD
EEEECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEEEEC
RSRDTDGHIVRLHQEDFCQALGFLPEQKYENEGGPSLKQCFTLLQEKSIRPAADRMALLR
CCCCCCCCEEEECHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
WTIFNLLIGNDDAHAKNLAMIFTDRGPRLAPFYDLICTQVYPDLTEKQAMRIGGENRPSW
HHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCH
ILQKHWDRFSESTAIKPNLVLKTLKEMSAAIALAAQTLSSEFIKKYGTCTIIEEILAVIE
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KRAESV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]