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The map label for this gene is glmU [H]

Identifier: 85858572

GI number: 85858572

Start: 730797

End: 731573

Strand: Direct

Name: glmU [H]

Synonym: SYN_02437

Alternate gene names: 85858572

Gene position: 730797-731573 (Clockwise)

Preceding gene: 85858570

Following gene: 85858573

Centisome position: 22.99

GC content: 46.07

Gene sequence:

>777_bases
ATGAATATTCCGATTCATAAGACTAATGATTATTCCCTGGGTGTGGTTATTCTTGCAGCAGGCAAGGGAACAAGGATGAG
ATCCGAGAAGGCCAAAGTACTGCATCATATCTGTGGTAATCCAATGCTTTTCTATACGATCAGGTTAGCCAGGAAAGTCC
TGGCGGAGAAAATTGTCGTTGTTGTCGGCCACCAGGCAGACGTAGTCAAGAAACATTTCAGTAATGGGGATTTGATCTTT
GCGGAACAGCGTGAACAACTTGGTACAGGGCATGCCGTCATGCAAACCCGGGAAGAATTTAAGAATTTTACAGGAAACAT
TCTGATTCTGTGTGGAGACGTTCCCCTTCTTTCCATAGAAACGGTCCGTCGTCTTATAAGCGGTCATGTGAGGGCAAATG
CCGCTGTTACAGTTCTTACCGCGCTGATGGATAATCCCGCCGGATATGGCCGTATTGTGAAAACGCCTGCGGGTGAAGTC
GTCAAAATTGTTGAGGAGCGGGACGCATCCGTCGAGGAGAAGAAAATTAAGGAAATCAATTCAGGAATCTATTGTGTTGA
TAGTCTATTTCTCTTCGATGCAATTGCTGAAATAAAGAATGACAATGCGCAGGGAGAATACTATCTGACCGACATCATAG
AAATCGCCTGTAAAAGAAGACGGCCCGTCAGGGCCGTTCTGGTGGATGATGCGGAAGAAATAATTGGCATTAATACTCCG
GAGCATCTTCAGCGGGCAGAAATGCGGATGTTTGAAGCATCCCGGCAGGGAGCATAA

Upstream 100 bases:

>100_bases
GGCATATCCTCAAATATATATGTGGATCAGCGATGGGCTAAATTGTCTTACATTGTCCCAGACAAAGTGATTGCATCTGA
AAAAAGCATGAAAGGATGTT

Downstream 100 bases:

>100_bases
TTTCCCTTGAGGCTCAGGGAAGGCATTCAAGCGGTAAAGCGGAGTGACGGCGCAGGCGGATACAAGACACGCTGCCGAGG
TTCCTCTTTTGAATTCAGCG

Product: UDP-N-acetylglucosamine pyrophosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MNIPIHKTNDYSLGVVILAAGKGTRMRSEKAKVLHHICGNPMLFYTIRLARKVLAEKIVVVVGHQADVVKKHFSNGDLIF
AEQREQLGTGHAVMQTREEFKNFTGNILILCGDVPLLSIETVRRLISGHVRANAAVTVLTALMDNPAGYGRIVKTPAGEV
VKIVEERDASVEEKKIKEINSGIYCVDSLFLFDAIAEIKNDNAQGEYYLTDIIEIACKRRRPVRAVLVDDAEEIIGINTP
EHLQRAEMRMFEASRQGA

Sequences:

>Translated_258_residues
MNIPIHKTNDYSLGVVILAAGKGTRMRSEKAKVLHHICGNPMLFYTIRLARKVLAEKIVVVVGHQADVVKKHFSNGDLIF
AEQREQLGTGHAVMQTREEFKNFTGNILILCGDVPLLSIETVRRLISGHVRANAAVTVLTALMDNPAGYGRIVKTPAGEV
VKIVEERDASVEEKKIKEINSGIYCVDSLFLFDAIAEIKNDNAQGEYYLTDIIEIACKRRRPVRAVLVDDAEEIIGINTP
EHLQRAEMRMFEASRQGA
>Mature_258_residues
MNIPIHKTNDYSLGVVILAAGKGTRMRSEKAKVLHHICGNPMLFYTIRLARKVLAEKIVVVVGHQADVVKKHFSNGDLIF
AEQREQLGTGHAVMQTREEFKNFTGNILILCGDVPLLSIETVRRLISGHVRANAAVTVLTALMDNPAGYGRIVKTPAGEV
VKIVEERDASVEEKKIKEINSGIYCVDSLFLFDAIAEIKNDNAQGEYYLTDIIEIACKRRRPVRAVLVDDAEEIIGINTP
EHLQRAEMRMFEASRQGA

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=244, Percent_Identity=40.5737704918033, Blast_Score=175, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 28691; Mature: 28691

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPIHKTNDYSLGVVILAAGKGTRMRSEKAKVLHHICGNPMLFYTIRLARKVLAEKIVV
CCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEE
VVGHQADVVKKHFSNGDLIFAEQREQLGTGHAVMQTREEFKNFTGNILILCGDVPLLSIE
EECCCHHHHHHHCCCCCEEEECCHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCEECHH
TVRRLISGHVRANAAVTVLTALMDNPAGYGRIVKTPAGEVVKIVEERDASVEEKKIKEIN
HHHHHHHCHHCCCHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHC
SGIYCVDSLFLFDAIAEIKNDNAQGEYYLTDIIEIACKRRRPVRAVLVDDAEEIIGINTP
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCH
EHLQRAEMRMFEASRQGA
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNIPIHKTNDYSLGVVILAAGKGTRMRSEKAKVLHHICGNPMLFYTIRLARKVLAEKIVV
CCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEE
VVGHQADVVKKHFSNGDLIFAEQREQLGTGHAVMQTREEFKNFTGNILILCGDVPLLSIE
EECCCHHHHHHHCCCCCEEEECCHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCEECHH
TVRRLISGHVRANAAVTVLTALMDNPAGYGRIVKTPAGEVVKIVEERDASVEEKKIKEIN
HHHHHHHCHHCCCHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHC
SGIYCVDSLFLFDAIAEIKNDNAQGEYYLTDIIEIACKRRRPVRAVLVDDAEEIIGINTP
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCH
EHLQRAEMRMFEASRQGA
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA