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The map label for this gene is trxB [H]

Identifier: 85858088

GI number: 85858088

Start: 258641

End: 259615

Strand: Direct

Name: trxB [H]

Synonym: SYN_01439

Alternate gene names: 85858088

Gene position: 258641-259615 (Clockwise)

Preceding gene: 85858085

Following gene: 85858089

Centisome position: 8.14

GC content: 57.64

Gene sequence:

>975_bases
ATGGAAGGAAATGAAAGTTTGAAATTGGTTTACGACATCATTGTGGTCGGCGGCGGTCCTGCGGGGCTGACCGCGGGACT
TTATGCGGCGCGGGGCGGGTTGAAGGCTCTGTTGCTGGAAGGAGAGTCGAGCGTCAGTCAGATCACGGTGACGGATCTGG
TGGAAAATTATCCCGGATTTCCGGAAGGAATCAACGGTTATGATCTGGTGGAGCGTTTCAGGACCCAGGCGGGCCGGTTT
GGTCTGAAGATTCTGACTGAAGACATCCGGGCAATCGATGCCGGGGCGGCGGAACACTGGATCGTTTCGGGAAGGGACTC
TGCCTATGAGGCGTTGTCCGTCATTCTCGCGACCGGGGCCAACTGGCGTCACCTGGGGGTGCCGGGAGAGGCGGCATTTA
CCGGGAAGGGCGTATCCTACTGTGCCACCTGTGACGGTCCCTTTTACCGGGATAGAGAGGTCGTCGTAGTGGGCGGCGGA
GATACCGCGGTTCAGGAAGCCCTCTTTCTGACCCGATTCGCCCGGAAAGTCACTATCGTACACCGGCGCGACCGCTTGCG
GGCGACCCCCATTCTGCAGGAGCGGGCCTTTGCCCATGAACGGATCGATTTTGCCTGGGATTCCGTAGTCGAGGAGATTC
AGGGAGGGGAATTTGTGGAAGGCGTGAGGATCCGCAATCTGAAAAATCCCGAAAAATCAAGGATTATTCCAGCCGACGGG
GCCTTCATCTTTGTGGGATTGACGCCCAATACCGGCTTCGTCCGGGGGCTGGTAAATTGTGATGAAAACGGCTACATCCT
TGCCGATGCCGAAATGAAGACCTCGGTAAAGGGGATATTTGCCTGTGGGGATTGCATTTCCAAACTGCTGCGGCAGGTCG
TTACCGCCTGCGGCGATGCCGCCACGGCGGCCTTTTCGGCTCAACTCCATGTGGAAGCCCTGAAGGGAGAGGATTACGGA
GGAAGAAAGGCCTGA

Upstream 100 bases:

>100_bases
TTTATGCTTTACAATTTCAAGGGATATCGATTAAATAGCAGTCTGTCTCAGCCGTTATGCATGCTTTTGAGATCAGGATC
TTCTCCAGGGGCGCGATTAT

Downstream 100 bases:

>100_bases
ACATGGATGCGTTTTTCCTCTTCTGGCAGCACCTTCCGGAAACCCTCCGGCCGGAACTCTTTTCCATCGGCTCCTTCCAG
GTCCGCTATTACAGCCTGAT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MEGNESLKLVYDIIVVGGGPAGLTAGLYAARGGLKALLLEGESSVSQITVTDLVENYPGFPEGINGYDLVERFRTQAGRF
GLKILTEDIRAIDAGAAEHWIVSGRDSAYEALSVILATGANWRHLGVPGEAAFTGKGVSYCATCDGPFYRDREVVVVGGG
DTAVQEALFLTRFARKVTIVHRRDRLRATPILQERAFAHERIDFAWDSVVEEIQGGEFVEGVRIRNLKNPEKSRIIPADG
AFIFVGLTPNTGFVRGLVNCDENGYILADAEMKTSVKGIFACGDCISKLLRQVVTACGDAATAAFSAQLHVEALKGEDYG
GRKA

Sequences:

>Translated_324_residues
MEGNESLKLVYDIIVVGGGPAGLTAGLYAARGGLKALLLEGESSVSQITVTDLVENYPGFPEGINGYDLVERFRTQAGRF
GLKILTEDIRAIDAGAAEHWIVSGRDSAYEALSVILATGANWRHLGVPGEAAFTGKGVSYCATCDGPFYRDREVVVVGGG
DTAVQEALFLTRFARKVTIVHRRDRLRATPILQERAFAHERIDFAWDSVVEEIQGGEFVEGVRIRNLKNPEKSRIIPADG
AFIFVGLTPNTGFVRGLVNCDENGYILADAEMKTSVKGIFACGDCISKLLRQVVTACGDAATAAFSAQLHVEALKGEDYG
GRKA
>Mature_324_residues
MEGNESLKLVYDIIVVGGGPAGLTAGLYAARGGLKALLLEGESSVSQITVTDLVENYPGFPEGINGYDLVERFRTQAGRF
GLKILTEDIRAIDAGAAEHWIVSGRDSAYEALSVILATGANWRHLGVPGEAAFTGKGVSYCATCDGPFYRDREVVVVGGG
DTAVQEALFLTRFARKVTIVHRRDRLRATPILQERAFAHERIDFAWDSVVEEIQGGEFVEGVRIRNLKNPEKSRIIPADG
AFIFVGLTPNTGFVRGLVNCDENGYILADAEMKTSVKGIFACGDCISKLLRQVVTACGDAATAAFSAQLHVEALKGEDYG
GRKA

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=302, Percent_Identity=27.4834437086093, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI226437568, Length=302, Percent_Identity=27.4834437086093, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI65787454, Length=302, Percent_Identity=27.4834437086093, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787114, Length=311, Percent_Identity=38.2636655948553, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI87081763, Length=309, Percent_Identity=34.3042071197411, Blast_Score=162, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6320560, Length=315, Percent_Identity=37.4603174603175, Blast_Score=222, Evalue=6e-59,
Organism=Saccharomyces cerevisiae, GI6321898, Length=315, Percent_Identity=36.1904761904762, Blast_Score=204, Evalue=2e-53,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34818; Mature: 34818

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGNESLKLVYDIIVVGGGPAGLTAGLYAARGGLKALLLEGESSVSQITVTDLVENYPGF
CCCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEHHHHHHHCCCC
PEGINGYDLVERFRTQAGRFGLKILTEDIRAIDAGAAEHWIVSGRDSAYEALSVILATGA
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCC
NWRHLGVPGEAAFTGKGVSYCATCDGPFYRDREVVVVGGGDTAVQEALFLTRFARKVTIV
CEEEECCCCCCEECCCCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEE
HRRDRLRATPILQERAFAHERIDFAWDSVVEEIQGGEFVEGVRIRNLKNPEKSRIIPADG
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCEEECCCCCCHHCEEEECCC
AFIFVGLTPNTGFVRGLVNCDENGYILADAEMKTSVKGIFACGDCISKLLRQVVTACGDA
CEEEEEECCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ATAAFSAQLHVEALKGEDYGGRKA
HHHHEEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MEGNESLKLVYDIIVVGGGPAGLTAGLYAARGGLKALLLEGESSVSQITVTDLVENYPGF
CCCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEHHHHHHHCCCC
PEGINGYDLVERFRTQAGRFGLKILTEDIRAIDAGAAEHWIVSGRDSAYEALSVILATGA
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCC
NWRHLGVPGEAAFTGKGVSYCATCDGPFYRDREVVVVGGGDTAVQEALFLTRFARKVTIV
CEEEECCCCCCEECCCCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEE
HRRDRLRATPILQERAFAHERIDFAWDSVVEEIQGGEFVEGVRIRNLKNPEKSRIIPADG
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCEEECCCCCCHHCEEEECCC
AFIFVGLTPNTGFVRGLVNCDENGYILADAEMKTSVKGIFACGDCISKLLRQVVTACGDA
CEEEEEECCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ATAAFSAQLHVEALKGEDYGGRKA
HHHHEEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]