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The map label for this gene is tadA [H]

Identifier: 85857921

GI number: 85857921

Start: 78720

End: 79283

Strand: Direct

Name: tadA [H]

Synonym: SYN_00164

Alternate gene names: 85857921

Gene position: 78720-79283 (Clockwise)

Preceding gene: 85857919

Following gene: 85857922

Centisome position: 2.48

GC content: 55.32

Gene sequence:

>564_bases
GTGGATACGGAAAACGGTTCTGCAGAGTCAGACAGAAATCCGGGTTTCCCATCAGGGGCATCGGAAACGGAAAGAGACCA
TGATGAGCGATGGATGCGCCTTGCCCTCGAAGAAGCCCGCCTGGCGGCGTCAGAGGGAGAGGTTCCGATCGGGGCGGTGA
TTGTCCGGGAAAACGAGGTGATCGCCAGAAGCCACAATATGCCGGTTGACCGTCATGATCCCACGGCCCATGCGGAGATT
CTGGCCATCCGGGAAGCCGCGGAAAAAATGAAAAATTACCGCCTGACGGGAATGACCCTCTACGTGACGCTTGAACCGTG
CATCATGTGTGCGGGGGCGATTCTTCAGGCCCGCCTGAAAAGGCTGGTTTATGGAACCGGCGACCCAAAGGGCGGTGCGG
TGGATTCCCTTTACCGGTTGCTTCAGGACAGCAGACTGAATCATTTCGTGGAGGTTACAGGGGGCGTTCTGCAGGCATCC
TGCGCGGAAATTTTAAGTGGATTTTTCCGGGAAAAGAGGGTAACATCCCCTCTCTTAAAATCAGAAGGACAGGTAAAGTC
TTGA

Upstream 100 bases:

>100_bases
ACGGAATAAATGAGGATTTTGTTTGCCGGCATCGGTCGCTTCACCTTTCATTGGCCGGGAAGCATAGAATAAGAACTTTT
TAAAATCAACAGGTGGTTCA

Downstream 100 bases:

>100_bases
TTTTGCGGAGAGGTACCGAAGTGGTCGTAACGGGATCGACTCGAAATCGATTTGGGGGCCAAAAGCTCTCACGGGGGTTC
GAATCCCCCTCTCTCCGCCA

Product: tRNA-specific adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MDTENGSAESDRNPGFPSGASETERDHDERWMRLALEEARLAASEGEVPIGAVIVRENEVIARSHNMPVDRHDPTAHAEI
LAIREAAEKMKNYRLTGMTLYVTLEPCIMCAGAILQARLKRLVYGTGDPKGGAVDSLYRLLQDSRLNHFVEVTGGVLQAS
CAEILSGFFREKRVTSPLLKSEGQVKS

Sequences:

>Translated_187_residues
MDTENGSAESDRNPGFPSGASETERDHDERWMRLALEEARLAASEGEVPIGAVIVRENEVIARSHNMPVDRHDPTAHAEI
LAIREAAEKMKNYRLTGMTLYVTLEPCIMCAGAILQARLKRLVYGTGDPKGGAVDSLYRLLQDSRLNHFVEVTGGVLQAS
CAEILSGFFREKRVTSPLLKSEGQVKS
>Mature_187_residues
MDTENGSAESDRNPGFPSGASETERDHDERWMRLALEEARLAASEGEVPIGAVIVRENEVIARSHNMPVDRHDPTAHAEI
LAIREAAEKMKNYRLTGMTLYVTLEPCIMCAGAILQARLKRLVYGTGDPKGGAVDSLYRLLQDSRLNHFVEVTGGVLQAS
CAEILSGFFREKRVTSPLLKSEGQVKS

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=171, Percent_Identity=28.6549707602339, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI145693172, Length=153, Percent_Identity=53.5947712418301, Blast_Score=165, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17554608, Length=96, Percent_Identity=44.7916666666667, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17541138, Length=154, Percent_Identity=32.4675324675325, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17555996, Length=111, Percent_Identity=37.8378378378378, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6325319, Length=101, Percent_Identity=39.6039603960396, Blast_Score=72, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21355527, Length=155, Percent_Identity=31.6129032258064, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 20567; Mature: 20567

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00903 CYT_DCMP_DEAMINASES ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTENGSAESDRNPGFPSGASETERDHDERWMRLALEEARLAASEGEVPIGAVIVRENEV
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCE
IARSHNMPVDRHDPTAHAEILAIREAAEKMKNYRLTGMTLYVTLEPCIMCAGAILQARLK
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEECCEEEEEEHHHHHHHHHHHHHHHHH
RLVYGTGDPKGGAVDSLYRLLQDSRLNHFVEVTGGVLQASCAEILSGFFREKRVTSPLLK
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEGQVKS
CCCCCCC
>Mature Secondary Structure
MDTENGSAESDRNPGFPSGASETERDHDERWMRLALEEARLAASEGEVPIGAVIVRENEV
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCE
IARSHNMPVDRHDPTAHAEILAIREAAEKMKNYRLTGMTLYVTLEPCIMCAGAILQARLK
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEECCEEEEEEHHHHHHHHHHHHHHHHH
RLVYGTGDPKGGAVDSLYRLLQDSRLNHFVEVTGGVLQASCAEILSGFFREKRVTSPLLK
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEGQVKS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]