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The map label for this gene is scoA [H]

Identifier: 85375689

GI number: 85375689

Start: 2874469

End: 2875191

Strand: Reverse

Name: scoA [H]

Synonym: ELI_14310

Alternate gene names: 85375689

Gene position: 2875191-2874469 (Counterclockwise)

Preceding gene: 85375692

Following gene: 85375688

Centisome position: 94.19

GC content: 62.1

Gene sequence:

>723_bases
ATGCAGAAACTCTTTCCCGATGCCGCCGCAGCGCTGGACGGCCTGCTCAATGACGACATGCTCATCGCCAGCGGCGGCTT
CGGCCTGTGCGGGATTCCCGAGCGCCTGCTCGATGCGATCCGCGACAGCGGGGTCAAGAACCTCACCTTCGCCAGCAACA
ATGCCGGGATCGACAACGAAGGCATCGGCAAGCTGCTGCGCACCAAGCAGGTCAAGAAGATGATCAGCTCCTATGTCGGC
GAGAACAAGGAATTCGAACGGCAATTCCTTGCCGGCGAGCTGGAGGTGGAGTTCTGCCCGCAGGGCACGCTGGCGGAGCG
GATGCGTGCGGGAGGCGCAGGCATCCCCGGTTTCTATACCAAGACCGGCGTCGGCACGCAGGTTGCCGAGGGGAAGGAAG
TGAAGACGTTCGCCAACCTGGACGGTCACAACGAAGACTATATCCTCGAGCGCGGCATCTTCGCCGACCTCTCGATCGTC
AAGGCGTGGAAGGCTGACGAGACGGGCAACACAATATTCCGCAAGACCGCGCGCAATTTCAACGTGCCCGCCGCGACCTG
CGGAAAGGTGTGCGTGGTCGAAGTCGAAGAGATCGTGCCCGCAGGATCGCTCGACCCCGATTGCATCCACCTGCCCGGTG
TCTTCGTCCAGCGCATGATCGTGGGCGCGCCTTACGACAAGAAGATTGAATTCCGCACCGTGCGCGAGCGCGAGAACGCC
TGA

Upstream 100 bases:

>100_bases
GACAGGCGGATGACAGTGCTTCGCCATGGCGCTAAAGGAGCGCGCAAGCGATGCGCATTGCCGCGCGTCCAACTCAACCG
ATGCCTAGCAAGAGGTCTTC

Downstream 100 bases:

>100_bases
GGCATGATTTCCGCCGGTCGCTTCCTGCTGATCGCCCCCTTGCTGGCCATGAGCCTGCAAGGCTGCGTCGCGGCGGTCAT
CCCGCTGGCGGCCGCAGGCG

Product: 3-oxoadipate CoA-succinyl transferase, alpha subunit

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MQKLFPDAAAALDGLLNDDMLIASGGFGLCGIPERLLDAIRDSGVKNLTFASNNAGIDNEGIGKLLRTKQVKKMISSYVG
ENKEFERQFLAGELEVEFCPQGTLAERMRAGGAGIPGFYTKTGVGTQVAEGKEVKTFANLDGHNEDYILERGIFADLSIV
KAWKADETGNTIFRKTARNFNVPAATCGKVCVVEVEEIVPAGSLDPDCIHLPGVFVQRMIVGAPYDKKIEFRTVRERENA

Sequences:

>Translated_240_residues
MQKLFPDAAAALDGLLNDDMLIASGGFGLCGIPERLLDAIRDSGVKNLTFASNNAGIDNEGIGKLLRTKQVKKMISSYVG
ENKEFERQFLAGELEVEFCPQGTLAERMRAGGAGIPGFYTKTGVGTQVAEGKEVKTFANLDGHNEDYILERGIFADLSIV
KAWKADETGNTIFRKTARNFNVPAATCGKVCVVEVEEIVPAGSLDPDCIHLPGVFVQRMIVGAPYDKKIEFRTVRERENA
>Mature_240_residues
MQKLFPDAAAALDGLLNDDMLIASGGFGLCGIPERLLDAIRDSGVKNLTFASNNAGIDNEGIGKLLRTKQVKKMISSYVG
ENKEFERQFLAGELEVEFCPQGTLAERMRAGGAGIPGFYTKTGVGTQVAEGKEVKTFANLDGHNEDYILERGIFADLSIV
KAWKADETGNTIFRKTARNFNVPAATCGKVCVVEVEEIVPAGSLDPDCIHLPGVFVQRMIVGAPYDKKIEFRTVRERENA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=252, Percent_Identity=51.984126984127, Blast_Score=258, Evalue=3e-69,
Organism=Homo sapiens, GI11545841, Length=238, Percent_Identity=47.8991596638655, Blast_Score=212, Evalue=2e-55,
Organism=Escherichia coli, GI1788551, Length=208, Percent_Identity=42.7884615384615, Blast_Score=169, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17531517, Length=248, Percent_Identity=48.3870967741936, Blast_Score=238, Evalue=3e-63,
Organism=Drosophila melanogaster, GI21358325, Length=247, Percent_Identity=48.582995951417, Blast_Score=238, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24655794, Length=247, Percent_Identity=48.582995951417, Blast_Score=238, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 26076; Mature: 26076

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLFPDAAAALDGLLNDDMLIASGGFGLCGIPERLLDAIRDSGVKNLTFASNNAGIDNE
CCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCH
GIGKLLRTKQVKKMISSYVGENKEFERQFLAGELEVEFCPQGTLAERMRAGGAGIPGFYT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCCC
KTGVGTQVAEGKEVKTFANLDGHNEDYILERGIFADLSIVKAWKADETGNTIFRKTARNF
CCCCCCCCCCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHCCC
NVPAATCGKVCVVEVEEIVPAGSLDPDCIHLPGVFVQRMIVGAPYDKKIEFRTVRERENA
CCCHHCCCCEEEEEHHHHCCCCCCCCCCEECCHHHHHHHHHCCCCCCCCHHEEHHHCCCC
>Mature Secondary Structure
MQKLFPDAAAALDGLLNDDMLIASGGFGLCGIPERLLDAIRDSGVKNLTFASNNAGIDNE
CCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCH
GIGKLLRTKQVKKMISSYVGENKEFERQFLAGELEVEFCPQGTLAERMRAGGAGIPGFYT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCCC
KTGVGTQVAEGKEVKTFANLDGHNEDYILERGIFADLSIVKAWKADETGNTIFRKTARNF
CCCCCCCCCCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHCCC
NVPAATCGKVCVVEVEEIVPAGSLDPDCIHLPGVFVQRMIVGAPYDKKIEFRTVRERENA
CCCHHCCCCEEEEEHHHHCCCCCCCCCCEECCHHHHHHHHHCCCCCCCCHHEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]