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The map label for this gene is nadD

Identifier: 85375472

GI number: 85375472

Start: 2664073

End: 2664732

Strand: Direct

Name: nadD

Synonym: ELI_13225

Alternate gene names: 85375472

Gene position: 2664073-2664732 (Clockwise)

Preceding gene: 85375469

Following gene: 85375473

Centisome position: 87.28

GC content: 65.45

Gene sequence:

>660_bases
TTGAGCGCGACCATCCGCACAGGGCTTCTCGGCGGCAGCTTCAACCCTGCCCACGGCGGGCACCGGCGCATCTCGCTCTT
TGCGCTGCAGGCGCTACGCCTCGATGAAGTGTGGTGGCTCGTCTCGCCGGGTAATCCGCTCAAATCTGCGGACGGCATGG
CATCGCACGAAGCGCGCTATCGTTCAGCGCTTGAGCAGGCCCGCCGCGCCCCGATCCGTGTGACGGCGATCGAAGCCCAA
TTGGGTACGCGCTACACCGTCGACACCCTGCGCACGCTGCGGGGACGCTATCCACGCCGCGAGTTCGTGTGGCTGATGGG
GGCTGACAACCTGGCGACATTCCACAGATGGAAGGCCTGGCGCGACATTGCGAGGACGATGCCGATTGCAGTCGTCGCCA
GGCCGGGTTATGATAAGGATGCCATTGCAAGCCCCGCAATGGCGTGGCTGCGGGGGCATCGTACCTCAGCCGCCGAATTT
CGCAGCCGGGGCAGATGGAGCGCACCGACCCTGGTGACATTGCGTTTCGATCCGGATTCACGCTCGGCCACGGCCATCCG
CCGCGCCGACCCGGACTGGCCGAGCCGGTATCGTTCCGGATTGCTGTTCGACCAGGTCACGCATCGGTCCATTTTCGGGG
AGCGTGAGCCCCCTGCATGA

Upstream 100 bases:

>100_bases
ACTGTCGGGAATCTACAACAATCGTGCGGTTGGAAGATTCGCCGGAAGCGAATACAGCATTTCGCGTGCGAACCCTGACC
GTCTCGAAGTGTGTCGCAGA

Downstream 100 bases:

>100_bases
TCGATCCAGGCGCATACCCCGGCAAGACTCGCAAACGGCTCGGTCGCTTCCTACCTACGCATCATGACAGGAGTATCCAA
TTCGCCCATGACACCGGCGC

Product: nicotinic acid mononucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSATIRTGLLGGSFNPAHGGHRRISLFALQALRLDEVWWLVSPGNPLKSADGMASHEARYRSALEQARRAPIRVTAIEAQ
LGTRYTVDTLRTLRGRYPRREFVWLMGADNLATFHRWKAWRDIARTMPIAVVARPGYDKDAIASPAMAWLRGHRTSAAEF
RSRGRWSAPTLVTLRFDPDSRSATAIRRADPDWPSRYRSGLLFDQVTHRSIFGEREPPA

Sequences:

>Translated_219_residues
MSATIRTGLLGGSFNPAHGGHRRISLFALQALRLDEVWWLVSPGNPLKSADGMASHEARYRSALEQARRAPIRVTAIEAQ
LGTRYTVDTLRTLRGRYPRREFVWLMGADNLATFHRWKAWRDIARTMPIAVVARPGYDKDAIASPAMAWLRGHRTSAAEF
RSRGRWSAPTLVTLRFDPDSRSATAIRRADPDWPSRYRSGLLFDQVTHRSIFGEREPPA
>Mature_218_residues
SATIRTGLLGGSFNPAHGGHRRISLFALQALRLDEVWWLVSPGNPLKSADGMASHEARYRSALEQARRAPIRVTAIEAQL
GTRYTVDTLRTLRGRYPRREFVWLMGADNLATFHRWKAWRDIARTMPIAVVARPGYDKDAIASPAMAWLRGHRTSAAEFR
SRGRWSAPTLVTLRFDPDSRSATAIRRADPDWPSRYRSGLLFDQVTHRSIFGEREPPA

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_ERYLH (Q2N6F4)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_459534.1
- ProteinModelPortal:   Q2N6F4
- STRING:   Q2N6F4
- GeneID:   3869350
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_13225
- NMPDR:   fig|314225.3.peg.379
- eggNOG:   COG1057
- HOGENOM:   HBG739448
- OMA:   IAVIARP
- ProtClustDB:   PRK00071
- BioCyc:   ELIT314225:ELI_13225-MONOMER
- HAMAP:   MF_00244
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.18

Molecular weight: Translated: 24778; Mature: 24646

Theoretical pI: Translated: 11.89; Mature: 11.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATIRTGLLGGSFNPAHGGHRRISLFALQALRLDEVWWLVSPGNPLKSADGMASHEARY
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHH
RSALEQARRAPIRVTAIEAQLGTRYTVDTLRTLRGRYPRREFVWLMGADNLATFHRWKAW
HHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHH
RDIARTMPIAVVARPGYDKDAIASPAMAWLRGHRTSAAEFRSRGRWSAPTLVTLRFDPDS
HHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEEECCCC
RSATAIRRADPDWPSRYRSGLLFDQVTHRSIFGEREPPA
CCHHHHCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SATIRTGLLGGSFNPAHGGHRRISLFALQALRLDEVWWLVSPGNPLKSADGMASHEARY
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHH
RSALEQARRAPIRVTAIEAQLGTRYTVDTLRTLRGRYPRREFVWLMGADNLATFHRWKAW
HHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHH
RDIARTMPIAVVARPGYDKDAIASPAMAWLRGHRTSAAEFRSRGRWSAPTLVTLRFDPDS
HHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEEECCCC
RSATAIRRADPDWPSRYRSGLLFDQVTHRSIFGEREPPA
CCHHHHCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA