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The map label for this gene is yesM [H]

Identifier: 85375407

GI number: 85375407

Start: 2601163

End: 2602413

Strand: Reverse

Name: yesM [H]

Synonym: ELI_12900

Alternate gene names: 85375407

Gene position: 2602413-2601163 (Counterclockwise)

Preceding gene: 85375408

Following gene: 85375406

Centisome position: 85.26

GC content: 64.11

Gene sequence:

>1251_bases
ATGATTGCAAACGAAACTTCTTCGCATCCGTCCGCCGTGCGCCTTCCGCTGCGCTATGTCGTCGGTTCGATCGTCGGCCT
GTGGGCGGTCTATTTCCTGCTCATCACGGCCCGCGGCGCCCTGGTTGGCATGGAATTCGACGCCGACCTGCTGCTGCGCC
GCACCGCCGTCTGCCTGGTGGGCGTGGCCGTCACCTTCGTCATCTGGCTGGTGCTGCGGCTGTTCGATGCCAGCAAGACC
TGGCTCAAGATCGTGATCGCGCTGATCGTGGCCTTCCCCGGGGCGGTGATGATCGCGCAGTTCAACCAGCTGATGTTCGC
CGAAATCCAGGAGCGGATGTACAACAAATTCGCCGAAGAGCGCGGCGTGAGCCTGCGCCGCGACGAGGCGGGCAATCTGC
TGGTTGAAATTCCCCAGCCGCGCGACTGGAAAGTGACCCGCGACAAAGATGCCGCCGAAGACCGGGATGCGCCGGTCTAC
ACCTTCACGCTCGAAGAGGCGAAGGAGGGCTATGCCCGCTGGCTCCCGCTCGTCGATGCTTCGCTGAGCCGCTATTACCT
GCTGCTGACCTGGGCGGCGCTCTATCTCGCCATGCTGGCCGGGGCGCAGGCGCGCGCGGCCGAACGGCGCGGCGAGCGTT
TCCGCAGTGCGGCCAAGGCGGCCGAGCTCCGCAGCCTGCGCTACCAGGTCAATCCGCACTTTCTGTTCAACACGCTCAAT
TCGCTGTCCTCGCTGGTGATGACCGGCAAGGCCGAACGGGCCGAGGAAATGATCCAGGCGATGTCGCGTTTCTATCGCCA
CAGCCTCGCCGACGACACCACCGCAGACGTGCAACTGGCGGACGAGTTCGAACTGCAGCGGCATTATCTCGAGATCGAGC
AATTGCGCTTCCCCGAGCGGTTGAAGATCGACTTCATCCTGCCGCCGGCGCTGGAAAATTGCCGCGTGCCCGGCATGATC
CTGCAGCCGTTGGTGGAAAATGCCGTCAAATACGGCGTTGCGCCGGTCAATCGCCCGGTCACCATCACCGTCAGCGCGGA
CGAGGAATTCGACCGGCTGGTGATCCGCGTGGCCGACGATGGCCCGGGCGTTCCGAAAGGCACCAAGCCCGGCTTCGGCA
TCGGTCTGGCCAATGTGAAGGACCGCATCGAAGCGCGGTTCGGGCGCGATGCCACCATCACGGCAGGCCCGGTCGAAGAC
GGCTATGTCACCGAATTGCGTCTGCCGCTCGAGAGAAAGGCCGCATCATGA

Upstream 100 bases:

>100_bases
GGGCCGTCGAGCGCGCCATCTCGCTCGACCAGCGGCAGAATCGCGTCGACTACGGTGCTGGCCTCGACAGGCCGTTTGGG
CCTAGAGGCAGGCTGACAAT

Downstream 100 bases:

>100_bases
GCGATGACAAGGATGTATCGCTGCGCACGCTGATCGTCGATGACGAACCGCTCGCGGTCGAGCGCATGCAGGTGATCTGC
GCCAAGCTGCCCAAGCTCAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MIANETSSHPSAVRLPLRYVVGSIVGLWAVYFLLITARGALVGMEFDADLLLRRTAVCLVGVAVTFVIWLVLRLFDASKT
WLKIVIALIVAFPGAVMIAQFNQLMFAEIQERMYNKFAEERGVSLRRDEAGNLLVEIPQPRDWKVTRDKDAAEDRDAPVY
TFTLEEAKEGYARWLPLVDASLSRYYLLLTWAALYLAMLAGAQARAAERRGERFRSAAKAAELRSLRYQVNPHFLFNTLN
SLSSLVMTGKAERAEEMIQAMSRFYRHSLADDTTADVQLADEFELQRHYLEIEQLRFPERLKIDFILPPALENCRVPGMI
LQPLVENAVKYGVAPVNRPVTITVSADEEFDRLVIRVADDGPGVPKGTKPGFGIGLANVKDRIEARFGRDATITAGPVED
GYVTELRLPLERKAAS

Sequences:

>Translated_416_residues
MIANETSSHPSAVRLPLRYVVGSIVGLWAVYFLLITARGALVGMEFDADLLLRRTAVCLVGVAVTFVIWLVLRLFDASKT
WLKIVIALIVAFPGAVMIAQFNQLMFAEIQERMYNKFAEERGVSLRRDEAGNLLVEIPQPRDWKVTRDKDAAEDRDAPVY
TFTLEEAKEGYARWLPLVDASLSRYYLLLTWAALYLAMLAGAQARAAERRGERFRSAAKAAELRSLRYQVNPHFLFNTLN
SLSSLVMTGKAERAEEMIQAMSRFYRHSLADDTTADVQLADEFELQRHYLEIEQLRFPERLKIDFILPPALENCRVPGMI
LQPLVENAVKYGVAPVNRPVTITVSADEEFDRLVIRVADDGPGVPKGTKPGFGIGLANVKDRIEARFGRDATITAGPVED
GYVTELRLPLERKAAS
>Mature_416_residues
MIANETSSHPSAVRLPLRYVVGSIVGLWAVYFLLITARGALVGMEFDADLLLRRTAVCLVGVAVTFVIWLVLRLFDASKT
WLKIVIALIVAFPGAVMIAQFNQLMFAEIQERMYNKFAEERGVSLRRDEAGNLLVEIPQPRDWKVTRDKDAAEDRDAPVY
TFTLEEAKEGYARWLPLVDASLSRYYLLLTWAALYLAMLAGAQARAAERRGERFRSAAKAAELRSLRYQVNPHFLFNTLN
SLSSLVMTGKAERAEEMIQAMSRFYRHSLADDTTADVQLADEFELQRHYLEIEQLRFPERLKIDFILPPALENCRVPGMI
LQPLVENAVKYGVAPVNRPVTITVSADEEFDRLVIRVADDGPGVPKGTKPGFGIGLANVKDRIEARFGRDATITAGPVED
GYVTELRLPLERKAAS

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=215, Percent_Identity=34.8837209302326, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788723, Length=194, Percent_Identity=36.0824742268041, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46664; Mature: 46664

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIANETSSHPSAVRLPLRYVVGSIVGLWAVYFLLITARGALVGMEFDADLLLRRTAVCLV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHH
GVAVTFVIWLVLRLFDASKTWLKIVIALIVAFPGAVMIAQFNQLMFAEIQERMYNKFAEE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RGVSLRRDEAGNLLVEIPQPRDWKVTRDKDAAEDRDAPVYTFTLEEAKEGYARWLPLVDA
CCCCEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
SLSRYYLLLTWAALYLAMLAGAQARAAERRGERFRSAAKAAELRSLRYQVNPHFLFNTLN
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SLSSLVMTGKAERAEEMIQAMSRFYRHSLADDTTADVQLADEFELQRHYLEIEQLRFPER
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCC
LKIDFILPPALENCRVPGMILQPLVENAVKYGVAPVNRPVTITVSADEEFDRLVIRVADD
EEEEEECCCCHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCC
GPGVPKGTKPGFGIGLANVKDRIEARFGRDATITAGPVEDGYVTELRLPLERKAAS
CCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCHHHCCCC
>Mature Secondary Structure
MIANETSSHPSAVRLPLRYVVGSIVGLWAVYFLLITARGALVGMEFDADLLLRRTAVCLV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHH
GVAVTFVIWLVLRLFDASKTWLKIVIALIVAFPGAVMIAQFNQLMFAEIQERMYNKFAEE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RGVSLRRDEAGNLLVEIPQPRDWKVTRDKDAAEDRDAPVYTFTLEEAKEGYARWLPLVDA
CCCCEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
SLSRYYLLLTWAALYLAMLAGAQARAAERRGERFRSAAKAAELRSLRYQVNPHFLFNTLN
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SLSSLVMTGKAERAEEMIQAMSRFYRHSLADDTTADVQLADEFELQRHYLEIEQLRFPER
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCC
LKIDFILPPALENCRVPGMILQPLVENAVKYGVAPVNRPVTITVSADEEFDRLVIRVADD
EEEEEECCCCHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCC
GPGVPKGTKPGFGIGLANVKDRIEARFGRDATITAGPVEDGYVTELRLPLERKAAS
CCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]