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The map label for this gene is pcd [H]

Identifier: 85375353

GI number: 85375353

Start: 2555577

End: 2556539

Strand: Direct

Name: pcd [H]

Synonym: ELI_12630

Alternate gene names: 85375353

Gene position: 2555577-2556539 (Clockwise)

Preceding gene: 85375352

Following gene: 85375354

Centisome position: 83.72

GC content: 65.73

Gene sequence:

>963_bases
ATGGGGCGTGAAAGGAATTCGGGCGTGGGCTGGCTGAGTTGGACGCTGATCGCGTTGGTCGCGCTGGCCCTTGTAGGTGC
AGGGCTATGGTGGTGGGCTCTCAGTGCGCAATCGGTCGCGACGCTCGATCGTGTCGATGCCCTCTTCACCGGCTCGAAGG
TCGAACAAAGCGCGCCGATCCCGTTCGGGACCGAGCTTGAGCAAGCGGTAGTGGTCGCCACACCCCTCGCGCCCTCGGCC
GAGCTTCGTCCGGTCGTGCTTTTCGTACATGGCGGCAGCTGGAACAGGGGCAGCGCGGTCGATTACGCTTTCGTCGCACG
CAATCTGGCGATCGAGGGCTATGTCGGCGTGAGCGCGGGCTACCGGCTGGTTCCGGGCGGCGAGTTTCCTGCCATGGTCG
AAGATGCCGCCAGGGCGCTGCGCTGGACGGTCGATCATATCGCCGATTATGGCGGCGACCCAGACCGGATATACCTGATG
GGTCATTCGGCCGGAGCCTATAACGTTGCGATGCTGGCGCTCGACGCGCAATGGCTGGAGCATGAGGACCTGCCGATGGA
TGCGATCAAGGGGGTCATCGGCTTGGCCGGCCCCTACGATTTCCTCCCGCTCGACAGCGACAGCACCAGCAACGCGTTCG
GCGGGGCGAGCGATCTCGCTGCGACCCAGCCGATCAATTTCGCCCGCAGCGATGCCCCGCCGATGCTGCTGCTCACCGGT
TATGCCGACACGACCGTGCGTCCGCGCAATTCCCGCGCGCTCGCGGCGGCGCTGACCCGGGAGGGGCAATCGACCGAGCC
CGTGCTGCTTCCCGGCCTGACCCACAGCGGTATCATCATGGCGCTGTCCCGCCCCTTCGAGGGCAATGGCGCGGTGAAGG
CGGCGATATTCGGATTTCTCGCGGCGAGGGAGCACGGCGATCGGGCAACACCTTCATCGCCTATTCAGGCCGCCGGAGGC
TAA

Upstream 100 bases:

>100_bases
GCGGCGGACTTTCTGAGCGCGGCGGGATTGTCGTATCAAGGCGAGACGGCCCAGATCGTCCGCGCGAAGGTCGCGGTCGG
GGACGATGCCTGAGCGGGTC

Downstream 100 bases:

>100_bases
TTGACCGCAATGCGCGCGCTCCTGTATCTCGTCGCCTGCCTGGCTGCGATCACGCTGTCGGTTCAACCGGCGACGGCACA
ATCCGTCCTGCGCGATGCGG

Product: carboxylesterase family protein

Products: alcohol; a carboxylate [C]

Alternate protein names: Phenylcarbamate hydrolase [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MGRERNSGVGWLSWTLIALVALALVGAGLWWWALSAQSVATLDRVDALFTGSKVEQSAPIPFGTELEQAVVVATPLAPSA
ELRPVVLFVHGGSWNRGSAVDYAFVARNLAIEGYVGVSAGYRLVPGGEFPAMVEDAARALRWTVDHIADYGGDPDRIYLM
GHSAGAYNVAMLALDAQWLEHEDLPMDAIKGVIGLAGPYDFLPLDSDSTSNAFGGASDLAATQPINFARSDAPPMLLLTG
YADTTVRPRNSRALAAALTREGQSTEPVLLPGLTHSGIIMALSRPFEGNGAVKAAIFGFLAAREHGDRATPSSPIQAAGG

Sequences:

>Translated_320_residues
MGRERNSGVGWLSWTLIALVALALVGAGLWWWALSAQSVATLDRVDALFTGSKVEQSAPIPFGTELEQAVVVATPLAPSA
ELRPVVLFVHGGSWNRGSAVDYAFVARNLAIEGYVGVSAGYRLVPGGEFPAMVEDAARALRWTVDHIADYGGDPDRIYLM
GHSAGAYNVAMLALDAQWLEHEDLPMDAIKGVIGLAGPYDFLPLDSDSTSNAFGGASDLAATQPINFARSDAPPMLLLTG
YADTTVRPRNSRALAAALTREGQSTEPVLLPGLTHSGIIMALSRPFEGNGAVKAAIFGFLAAREHGDRATPSSPIQAAGG
>Mature_319_residues
GRERNSGVGWLSWTLIALVALALVGAGLWWWALSAQSVATLDRVDALFTGSKVEQSAPIPFGTELEQAVVVATPLAPSAE
LRPVVLFVHGGSWNRGSAVDYAFVARNLAIEGYVGVSAGYRLVPGGEFPAMVEDAARALRWTVDHIADYGGDPDRIYLMG
HSAGAYNVAMLALDAQWLEHEDLPMDAIKGVIGLAGPYDFLPLDSDSTSNAFGGASDLAATQPINFARSDAPPMLLLTGY
ADTTVRPRNSRALAAALTREGQSTEPVLLPGLTHSGIIMALSRPFEGNGAVKAAIFGFLAAREHGDRATPSSPIQAAGG

Specific function: May degrade the phenylcarbamate herbicides phenmedipham and desmedipham cometabolically by hydrolyzing their central carbamate linkages. Conveys resistance to the herbicide phenmedipham [H]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-B carboxylesterase/lipase family [H]

Homologues:

Organism=Homo sapiens, GI192807282, Length=231, Percent_Identity=26.8398268398268, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI224465228, Length=145, Percent_Identity=32.4137931034483, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002018
- InterPro:   IPR019826
- InterPro:   IPR019819 [H]

Pfam domain/function: PF00135 COesterase [H]

EC number: 3.1.1.- [C]

Molecular weight: Translated: 33624; Mature: 33493

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRERNSGVGWLSWTLIALVALALVGAGLWWWALSAQSVATLDRVDALFTGSKVEQSAPI
CCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCC
PFGTELEQAVVVATPLAPSAELRPVVLFVHGGSWNRGSAVDYAFVARNLAIEGYVGVSAG
CCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHEEEEEEEECCCC
YRLVPGGEFPAMVEDAARALRWTVDHIADYGGDPDRIYLMGHSAGAYNVAMLALDAQWLE
CEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEEHHHHC
HEDLPMDAIKGVIGLAGPYDFLPLDSDSTSNAFGGASDLAATQPINFARSDAPPMLLLTG
CCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
YADTTVRPRNSRALAAALTREGQSTEPVLLPGLTHSGIIMALSRPFEGNGAVKAAIFGFL
CCCCCCCCCCCCHHHHHHHCCCCCCCCEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHH
AAREHGDRATPSSPIQAAGG
HHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GRERNSGVGWLSWTLIALVALALVGAGLWWWALSAQSVATLDRVDALFTGSKVEQSAPI
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCC
PFGTELEQAVVVATPLAPSAELRPVVLFVHGGSWNRGSAVDYAFVARNLAIEGYVGVSAG
CCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHEEEEEEEECCCC
YRLVPGGEFPAMVEDAARALRWTVDHIADYGGDPDRIYLMGHSAGAYNVAMLALDAQWLE
CEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEEHHHHC
HEDLPMDAIKGVIGLAGPYDFLPLDSDSTSNAFGGASDLAATQPINFARSDAPPMLLLTG
CCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
YADTTVRPRNSRALAAALTREGQSTEPVLLPGLTHSGIIMALSRPFEGNGAVKAAIFGFL
CCCCCCCCCCCCHHHHHHHCCCCCCCCEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHH
AAREHGDRATPSSPIQAAGG
HHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400211 [H]