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The map label for this gene is frc [H]

Identifier: 85375312

GI number: 85375312

Start: 2513294

End: 2514475

Strand: Direct

Name: frc [H]

Synonym: ELI_12425

Alternate gene names: 85375312

Gene position: 2513294-2514475 (Clockwise)

Preceding gene: 85375311

Following gene: 85375314

Centisome position: 82.34

GC content: 63.28

Gene sequence:

>1182_bases
ATGATCGCACCCGGTGACGGCAAGCCCATGCTCGAAGGCGTGACGGTCATCGACCTCACCAGCATGGTGTTCGGCCCCTA
TTGCACGCAGATCCTCGCCGATTTCGGGGCCGAGGTGATCAAGGTCGAGAGCCCGGGCGGCGATACGCAGCGGCACACCA
GCAAATACGCCGTCAATCGCGGGATGAGCGCGACGCATATCGCGCTCAACCGCGGCAAGAAATCGATCATCCTCGACCTG
AAGCAGGAGGCAGACGCCGAGGTGCTGCGCGGCCTGCTCGCCGAGGCAGACGTCATGGTGCACAACATTCGCGGCGCTTC
GATCGAGCGGCTCGGCTTCGGCTACGACGCGGTGCGCGAAATCGCGCCGGAGATAATCTACGCGCATTGCGTCGGCTATG
GCTCGGGTGGGCGCTATGCCGGGTTGCAGGCCTTCGACGATACGATTCAGGCGGCGACGGGCACAGTCACACTGCTGAGC
GAAGTCGACGGCGATCCGACCCCGCGCTTTCTGCCCTCGCTGGTCGCCGACAAGGTCTCCGGCCTGCACGGTGCGTACGC
GATCATGGCAGCATTGATCCATCGCCTCCGTACCGGACGCGGGCAGGCGATCGAAATTCCGATGTTCGAGCTGTTTGCCG
GTTTCATGATGAAAGAGCACATGGGCGGCCTCACTTTCGATCCGCCCAAGGGACCGCCCGGCTTCACGCGCCAGCTCGAT
CCGCTGCAAAAGCCCTTCGCCGCCAAGGACGGACATGTCGCCATCGCGCCAGCGCATCTGGAGGGTTTCCGCGACCTTGT
CGCCTTGCTTGGGGACGAGGAATTCGCCGCCGAAGAGCGCTTTGCCGACCGGCGCGGACTGTTCTTCAACCAGGCCGAAT
TGCAGCGGCGGGCCGCCGAATTAAGTCCGAACTTCACGGTTGCCGAACTTGAGGACATCTGCCGTTCCAACAGCCTCCCC
GCGATGAAGGTCAGCCACTTCACCGAAATCATCGACGATCCGCACCTGGTTGAGACAGGCTTCATCCAGCGCACGACCCA
TCCCAGCGAAGGCGGTGTGGTCGAAATGCGCGAGCCGAGCAGCTTCTCCGACTGGGAGCACGAACTCGGCCTGCACGCCC
CGCTTCTTGACGAAAATGGCGAAGAATTGCGCGAGCGCGCAGCGAAAAACCGCAGGCGCTAG

Upstream 100 bases:

>100_bases
CAGGGGCGCAAACTGGTCGAAGCGCGGCTGGAGGCGAGCCCCGAACAGCTCGCCGATATCGAGACACCGCTCAAGGAACT
GCTGTGAGGAGGGCGCCCTT

Downstream 100 bases:

>100_bases
ACTAGCCGCGCTTTCGCCCATTGTGCCGCTTCGGCGACGACGGGATCGGGATCGGCCAGCAGGGCATCGACCGGTTCGCG
CAAAGCCGCGTCGCCGCTGT

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MIAPGDGKPMLEGVTVIDLTSMVFGPYCTQILADFGAEVIKVESPGGDTQRHTSKYAVNRGMSATHIALNRGKKSIILDL
KQEADAEVLRGLLAEADVMVHNIRGASIERLGFGYDAVREIAPEIIYAHCVGYGSGGRYAGLQAFDDTIQAATGTVTLLS
EVDGDPTPRFLPSLVADKVSGLHGAYAIMAALIHRLRTGRGQAIEIPMFELFAGFMMKEHMGGLTFDPPKGPPGFTRQLD
PLQKPFAAKDGHVAIAPAHLEGFRDLVALLGDEEFAAEERFADRRGLFFNQAELQRRAAELSPNFTVAELEDICRSNSLP
AMKVSHFTEIIDDPHLVETGFIQRTTHPSEGGVVEMREPSSFSDWEHELGLHAPLLDENGEELRERAAKNRRR

Sequences:

>Translated_393_residues
MIAPGDGKPMLEGVTVIDLTSMVFGPYCTQILADFGAEVIKVESPGGDTQRHTSKYAVNRGMSATHIALNRGKKSIILDL
KQEADAEVLRGLLAEADVMVHNIRGASIERLGFGYDAVREIAPEIIYAHCVGYGSGGRYAGLQAFDDTIQAATGTVTLLS
EVDGDPTPRFLPSLVADKVSGLHGAYAIMAALIHRLRTGRGQAIEIPMFELFAGFMMKEHMGGLTFDPPKGPPGFTRQLD
PLQKPFAAKDGHVAIAPAHLEGFRDLVALLGDEEFAAEERFADRRGLFFNQAELQRRAAELSPNFTVAELEDICRSNSLP
AMKVSHFTEIIDDPHLVETGFIQRTTHPSEGGVVEMREPSSFSDWEHELGLHAPLLDENGEELRERAAKNRRR
>Mature_393_residues
MIAPGDGKPMLEGVTVIDLTSMVFGPYCTQILADFGAEVIKVESPGGDTQRHTSKYAVNRGMSATHIALNRGKKSIILDL
KQEADAEVLRGLLAEADVMVHNIRGASIERLGFGYDAVREIAPEIIYAHCVGYGSGGRYAGLQAFDDTIQAATGTVTLLS
EVDGDPTPRFLPSLVADKVSGLHGAYAIMAALIHRLRTGRGQAIEIPMFELFAGFMMKEHMGGLTFDPPKGPPGFTRQLD
PLQKPFAAKDGHVAIAPAHLEGFRDLVALLGDEEFAAEERFADRRGLFFNQAELQRRAAELSPNFTVAELEDICRSNSLP
AMKVSHFTEIIDDPHLVETGFIQRTTHPSEGGVVEMREPSSFSDWEHELGLHAPLLDENGEELRERAAKNRRR

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=374, Percent_Identity=26.2032085561497, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI300863124, Length=336, Percent_Identity=27.3809523809524, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI266456254, Length=341, Percent_Identity=29.6187683284457, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI42794625, Length=341, Percent_Identity=29.6187683284457, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI266458393, Length=226, Percent_Identity=34.5132743362832, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI266458397, Length=226, Percent_Identity=34.5132743362832, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI300863126, Length=346, Percent_Identity=24.5664739884393, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI42822893, Length=144, Percent_Identity=36.8055555555556, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI266458395, Length=144, Percent_Identity=36.8055555555556, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI87082093, Length=290, Percent_Identity=33.448275862069, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1788717, Length=397, Percent_Identity=26.9521410579345, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786222, Length=345, Percent_Identity=25.2173913043478, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115535051, Length=341, Percent_Identity=23.4604105571848, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI32564160, Length=295, Percent_Identity=24.406779661017, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648431, Length=375, Percent_Identity=29.6, Blast_Score=168, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24585488, Length=201, Percent_Identity=28.3582089552239, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 42958; Mature: 42958

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAPGDGKPMLEGVTVIDLTSMVFGPYCTQILADFGAEVIKVESPGGDTQRHTSKYAVNR
CCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHC
GMSATHIALNRGKKSIILDLKQEADAEVLRGLLAEADVMVHNIRGASIERLGFGYDAVRE
CCCHHHHHHHCCCCEEEEECHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHH
IAPEIIYAHCVGYGSGGRYAGLQAFDDTIQAATGTVTLLSEVDGDPTPRFLPSLVADKVS
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHH
GLHGAYAIMAALIHRLRTGRGQAIEIPMFELFAGFMMKEHMGGLTFDPPKGPPGFTRQLD
CCHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PLQKPFAAKDGHVAIAPAHLEGFRDLVALLGDEEFAAEERFADRRGLFFNQAELQRRAAE
HHHCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEECHHHHHHHHHH
LSPNFTVAELEDICRSNSLPAMKVSHFTEIIDDPHLVETGFIQRTTHPSEGGVVEMREPS
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEECCCCEEECCCCCCCCEEEECCCC
SFSDWEHELGLHAPLLDENGEELRERAAKNRRR
CCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MIAPGDGKPMLEGVTVIDLTSMVFGPYCTQILADFGAEVIKVESPGGDTQRHTSKYAVNR
CCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHC
GMSATHIALNRGKKSIILDLKQEADAEVLRGLLAEADVMVHNIRGASIERLGFGYDAVRE
CCCHHHHHHHCCCCEEEEECHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHH
IAPEIIYAHCVGYGSGGRYAGLQAFDDTIQAATGTVTLLSEVDGDPTPRFLPSLVADKVS
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHH
GLHGAYAIMAALIHRLRTGRGQAIEIPMFELFAGFMMKEHMGGLTFDPPKGPPGFTRQLD
CCHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PLQKPFAAKDGHVAIAPAHLEGFRDLVALLGDEEFAAEERFADRRGLFFNQAELQRRAAE
HHHCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEECHHHHHHHHHH
LSPNFTVAELEDICRSNSLPAMKVSHFTEIIDDPHLVETGFIQRTTHPSEGGVVEMREPS
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEECCCCEEECCCCCCCCEEEECCCC
SFSDWEHELGLHAPLLDENGEELRERAAKNRRR
CCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]