BacMap

Definition	Erythrobacter litoralis HTCC2594 chromosome, complete genome.
Accession	NC_007722
Length	3,052,398

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The map label for this gene is fabG [H]

Identifier: 85375290

GI number: 85375290

Start: 2487085

End: 2487822

Strand: Reverse

Name: fabG [H]

Synonym: ELI_12315

Alternate gene names: 85375290

Gene position: 2487822-2487085 (Counterclockwise)

Preceding gene: 85375291

Following gene: 85375288

Centisome position: 81.5

GC content: 62.87

Gene sequence:

>738_bases
ATGAGCGATCCACTAGACTTCACAGGCAAGCGCGTCCTCATCGTCGGCGGTTCGAGCGGGATCGGCAACGGCATGGCGCA
GGCGTTTCATGGACGAGGGGCAGAAGTACATGTCTGGGGCACACGACCCGGCGCAGCGGATTATGCCGACGAAGACGGCT
CGGACCTCACCGGCCTGCACTACACCCAGGTCGATGTGAGCGACCCGTCGCAGATCGAAAACGCGCCCGATTACGACAGT
CTCGATGTCCTTGTCTGCTGCCAGGGTGCTGTCGAATATCGCCGCGCCGAGTTCGAGCGCGAGGGTTGGGACCGGGTGCT
GGCGGTCAACCTCAGCTCGATCATGGACTGCGCGCGCAAATACCGCACCGCACTGGCCGAAGCGAAAGGCAGCCTCATTG
CAGTCAGCTCGACCGCCGCTTTCCACGCGACGGTCGGCAATCCCGCCTATGGCGCGAGCAAGGCGGGCGCGGTGGCACTG
GTGCGCAATCTTGCCGCTGCCTTTGCCGAAGAGGGCATTCGCGTGAACGGGATTGCGCCGGGTTTTGTCGCGACCAAGAT
GACCAAGGTCACGACCGATCACCCCAAGCGCCTCGAAGGCGCGCTCGCCAAGATCCCGCTCCATCGAATGGGTGAGCCAA
GTGAATTGGCAGGGGCGGCATTGTTTCTTGCCTCTCCCCTGTCCTCTTACATATTGGGCCAGACCATCGTCGTCGACGGC
GGGTTGACCTTGTCCTAG

Upstream 100 bases:

>100_bases
TCGACCGGGTCGAGACGGTAGAGCTGGCCGGTGAGCCCAAGCGCTCGACCTCGACTTTCGTCGGTGGGCTCAAGACCCTG
CCTCTGCGGATTACCCCGGC

Downstream 100 bases:

>100_bases
CCCAGCAACCGCTGTGCCATTGCTCGCACTTCAGCGCCCATGTCCTCGCGCTCCAGCGCCAGCGCCAGCGTCGCCTCGAC
GAAGCCGAGTTTGCTGCCGC

Product: oxidoreductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSDPLDFTGKRVLIVGGSSGIGNGMAQAFHGRGAEVHVWGTRPGAADYADEDGSDLTGLHYTQVDVSDPSQIENAPDYDS
LDVLVCCQGAVEYRRAEFEREGWDRVLAVNLSSIMDCARKYRTALAEAKGSLIAVSSTAAFHATVGNPAYGASKAGAVAL
VRNLAAAFAEEGIRVNGIAPGFVATKMTKVTTDHPKRLEGALAKIPLHRMGEPSELAGAALFLASPLSSYILGQTIVVDG
GLTLS

Sequences:

>Translated_245_residues
MSDPLDFTGKRVLIVGGSSGIGNGMAQAFHGRGAEVHVWGTRPGAADYADEDGSDLTGLHYTQVDVSDPSQIENAPDYDS
LDVLVCCQGAVEYRRAEFEREGWDRVLAVNLSSIMDCARKYRTALAEAKGSLIAVSSTAAFHATVGNPAYGASKAGAVAL
VRNLAAAFAEEGIRVNGIAPGFVATKMTKVTTDHPKRLEGALAKIPLHRMGEPSELAGAALFLASPLSSYILGQTIVVDG
GLTLS
>Mature_244_residues
SDPLDFTGKRVLIVGGSSGIGNGMAQAFHGRGAEVHVWGTRPGAADYADEDGSDLTGLHYTQVDVSDPSQIENAPDYDSL
DVLVCCQGAVEYRRAEFEREGWDRVLAVNLSSIMDCARKYRTALAEAKGSLIAVSSTAAFHATVGNPAYGASKAGAVALV
RNLAAAFAEEGIRVNGIAPGFVATKMTKVTTDHPKRLEGALAKIPLHRMGEPSELAGAALFLASPLSSYILGQTIVVDGG
LTLS

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=35.1020408163265, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=30.2788844621514, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=30.6122448979592, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=28.6821705426357, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=28.6852589641434, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=29.5833333333333, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=27.9527559055118, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=26.984126984127, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI66933014, Length=195, Percent_Identity=28.7179487179487, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=29.0196078431373, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=29.5918367346939, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=28.9473684210526, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=32.6612903225806, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=29.1338582677165, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=31.0756972111554, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790717, Length=257, Percent_Identity=29.5719844357977, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=31.7460317460317, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=31.640625, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=30.7692307692308, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI2367365, Length=238, Percent_Identity=29.8319327731092, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=31.1740890688259, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787545, Length=257, Percent_Identity=28.7937743190661, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=27.5303643724696, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789057, Length=161, Percent_Identity=29.1925465838509, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=26.9387755102041, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=31.6602316602317, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=30.7377049180328, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=31.2, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=29.7709923664122, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=30.9160305343511, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=30.1158301158301, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI72000259, Length=273, Percent_Identity=29.3040293040293, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=28.9473684210526, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=30.6818181818182, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=29.9270072992701, Blast_Score=90, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=31.4393939393939, Blast_Score=90, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=28.3400809716599, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=28.1853281853282, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=30.6818181818182, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=29.0566037735849, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=27.7777777777778, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=278, Percent_Identity=26.978417266187, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=29.8850574712644, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=31.5789473684211, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=29.6577946768061, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=30.5660377358491, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=29.6992481203008, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=250, Percent_Identity=30, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=30.9433962264151, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193207185, Length=147, Percent_Identity=32.6530612244898, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=28.7449392712551, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=246, Percent_Identity=25.609756097561, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=27.2357723577236, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=24.2063492063492, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=30.078125, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=31.6, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=32.258064516129, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI23397609, Length=245, Percent_Identity=29.7959183673469, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=32.1285140562249, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24643142, Length=242, Percent_Identity=28.9256198347107, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=29.5546558704453, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=29.0196078431373, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644337, Length=119, Percent_Identity=37.8151260504202, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=28.7449392712551, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25622; Mature: 25491

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPLDFTGKRVLIVGGSSGIGNGMAQAFHGRGAEVHVWGTRPGAADYADEDGSDLTGLH
CCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCEE
YTQVDVSDPSQIENAPDYDSLDVLVCCQGAVEYRRAEFEREGWDRVLAVNLSSIMDCARK
EEEEECCCCHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHH
YRTALAEAKGSLIAVSSTAAFHATVGNPAYGASKAGAVALVRNLAAAFAEEGIRVNGIAP
HHHHHHHCCCCEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCC
GFVATKMTKVTTDHPKRLEGALAKIPLHRMGEPSELAGAALFLASPLSSYILGQTIVVDG
CHHHHHHHHCCCCCCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEC
GLTLS
CEECC
>Mature Secondary Structure 
SDPLDFTGKRVLIVGGSSGIGNGMAQAFHGRGAEVHVWGTRPGAADYADEDGSDLTGLH
CCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCEE
YTQVDVSDPSQIENAPDYDSLDVLVCCQGAVEYRRAEFEREGWDRVLAVNLSSIMDCARK
EEEEECCCCHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHH
YRTALAEAKGSLIAVSSTAAFHATVGNPAYGASKAGAVALVRNLAAAFAEEGIRVNGIAP
HHHHHHHCCCCEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCC
GFVATKMTKVTTDHPKRLEGALAKIPLHRMGEPSELAGAALFLASPLSSYILGQTIVVDG
CHHHHHHHHCCCCCCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEC
GLTLS
CEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]