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The map label for this gene is murA [H]

Identifier: 85375288

GI number: 85375288

Start: 2484804

End: 2486147

Strand: Reverse

Name: murA [H]

Synonym: ELI_12305

Alternate gene names: 85375288

Gene position: 2486147-2484804 (Counterclockwise)

Preceding gene: 85375290

Following gene: 85375284

Centisome position: 81.45

GC content: 64.51

Gene sequence:

>1344_bases
ATGACTGTGCCGGTGACTGCGCCGGTTGCCAGCGCGGGCGAATGGGCTAAACGCCTTGGCATGGACAAACTCGTAATTCG
TGGCGGCAATCGCCTTTCCGGCACAATCCCGATTTCGGGTGCCAAGAACTCCGCGTTGACGCTCATTCCCTGTGCGCTGT
TGACCGACGAACCGCTCACCTTGCGCAACCTGCCGCGCCTGGCTGATATCGACGGCTTCCAGCATCTGATGAACCAGTTC
GGCGTGATGACCGCAGTGCAGGGCAAGCGCCCGGAGGATTTCGGCCGCGTCATGACCATGGAAGCGACGCGGATCACCTC
CAGCGTCGCCCCCTATGATCTCGTCCGCAAGATGCGCGCCTCGATCCTGGTGCTCGGCCCGATGCTCGCGCGGATGGGGG
AGGCGACCGTGTCGCTGCCCGGCGGCTGCGCGATCGGCAACCGGCCGATCGACCTGCATCTCAAGGCGCTCGAAGCGCTG
GGGGCTGAGATCGAAATGGCGCAAGGCTACGTGAAGGCAGTTGCGCCAGACGGCGGATTGCCCGGCGGGAAGTTCGATTT
TCCCGTCGTTTCGGTCGGCGCGACCGAGAATGCGGTGATGGCGGCGGTCCTCGCCAAGGGGACCAGCCACCTGTTCAACG
CCGCGCGCGAGCCGGAAATCGTCGACCTGTGCAAATTGCTGGCCGCGATGGGCGCGGAGATCGAGGGAATCGGCTCCTCC
GATCTCGTCATTCACGGCGTCAAGCGGCTGCACGGTGCGACCTATCGCGTCATGGGCGACCGGATCGAGGCGGGATCCTA
TGCTTGCGCCGCGGCAATCACCGGCGGCGACGTAATGCTGGAAGGTGCGAATGCGGAGGAGATGCAGGCGACCATCCACG
CCTTGCGCAATATCGGCGTGACCGTGGAAGAGACCAAGAGCGGCGTGCACATCATCGCGGACGGCCCGCTCAAGGCCACC
AATCTCACGACGGCGCCCTATCCCGGCCTCGCCACCGACATGCAGGCGCAGCTGATGAGCCTGCTGTGCAAGGCCGAGGG
CACCAGCGTGCTGAAGGAAACGATCTTCGAGAACCGCTTCATGCACGTACCCGAACTCAACCGGATGGGCGCGGATATCG
AAACCGAAGGGCGCACGGCGATCGTCAAGGGTGTCGAGACGCTGACCGGTGCCGAAGTCATGGCGACCGACCTGCGCGCG
TCGATGAGCCTGATTATTGCCGGGCTGGCCGCAGAGGGCGAGACGCAGGTCCGCCGCATCTATCACCTGGATCGGGGCTA
CGAACGGCTGGAAGAGAAACTGCAACTGGTCGGCGCCGACATCGAACGGGTGGGCGACGACTAG

Upstream 100 bases:

>100_bases
ACGGGGAAAACGGCTTTTCTAATGGGTTTATGGGCGGTCATGGCTCTGGCGATAAGGCGTCTGGTCGCGCCGTCAACTGT
CGCAGCGATGTTGCCGTACT

Downstream 100 bases:

>100_bases
ATTGAATTAAGATTGCGCCCCATCGAAATGCGGCGCTCTGGCTCCGATCCCGCCCCGTCGGCAAGACGGCAGTACCGCCA
CTGAATAGAGCCAGCCGCGA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTVPVTAPVASAGEWAKRLGMDKLVIRGGNRLSGTIPISGAKNSALTLIPCALLTDEPLTLRNLPRLADIDGFQHLMNQF
GVMTAVQGKRPEDFGRVMTMEATRITSSVAPYDLVRKMRASILVLGPMLARMGEATVSLPGGCAIGNRPIDLHLKALEAL
GAEIEMAQGYVKAVAPDGGLPGGKFDFPVVSVGATENAVMAAVLAKGTSHLFNAAREPEIVDLCKLLAAMGAEIEGIGSS
DLVIHGVKRLHGATYRVMGDRIEAGSYACAAAITGGDVMLEGANAEEMQATIHALRNIGVTVEETKSGVHIIADGPLKAT
NLTTAPYPGLATDMQAQLMSLLCKAEGTSVLKETIFENRFMHVPELNRMGADIETEGRTAIVKGVETLTGAEVMATDLRA
SMSLIIAGLAAEGETQVRRIYHLDRGYERLEEKLQLVGADIERVGDD

Sequences:

>Translated_447_residues
MTVPVTAPVASAGEWAKRLGMDKLVIRGGNRLSGTIPISGAKNSALTLIPCALLTDEPLTLRNLPRLADIDGFQHLMNQF
GVMTAVQGKRPEDFGRVMTMEATRITSSVAPYDLVRKMRASILVLGPMLARMGEATVSLPGGCAIGNRPIDLHLKALEAL
GAEIEMAQGYVKAVAPDGGLPGGKFDFPVVSVGATENAVMAAVLAKGTSHLFNAAREPEIVDLCKLLAAMGAEIEGIGSS
DLVIHGVKRLHGATYRVMGDRIEAGSYACAAAITGGDVMLEGANAEEMQATIHALRNIGVTVEETKSGVHIIADGPLKAT
NLTTAPYPGLATDMQAQLMSLLCKAEGTSVLKETIFENRFMHVPELNRMGADIETEGRTAIVKGVETLTGAEVMATDLRA
SMSLIIAGLAAEGETQVRRIYHLDRGYERLEEKLQLVGADIERVGDD
>Mature_446_residues
TVPVTAPVASAGEWAKRLGMDKLVIRGGNRLSGTIPISGAKNSALTLIPCALLTDEPLTLRNLPRLADIDGFQHLMNQFG
VMTAVQGKRPEDFGRVMTMEATRITSSVAPYDLVRKMRASILVLGPMLARMGEATVSLPGGCAIGNRPIDLHLKALEALG
AEIEMAQGYVKAVAPDGGLPGGKFDFPVVSVGATENAVMAAVLAKGTSHLFNAAREPEIVDLCKLLAAMGAEIEGIGSSD
LVIHGVKRLHGATYRVMGDRIEAGSYACAAAITGGDVMLEGANAEEMQATIHALRNIGVTVEETKSGVHIIADGPLKATN
LTTAPYPGLATDMQAQLMSLLCKAEGTSVLKETIFENRFMHVPELNRMGADIETEGRTAIVKGVETLTGAEVMATDLRAS
MSLIIAGLAAEGETQVRRIYHLDRGYERLEEKLQLVGADIERVGDD

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=425, Percent_Identity=49.8823529411765, Blast_Score=400, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 47321; Mature: 47190

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPVTAPVASAGEWAKRLGMDKLVIRGGNRLSGTIPISGAKNSALTLIPCALLTDEPLT
CCCCCCCCCCCHHHHHHHCCCCEEEEECCCEEEEEEEECCCCCCCEEEEEEEHHCCCCCH
LRNLPRLADIDGFQHLMNQFGVMTAVQGKRPEDFGRVMTMEATRITSSVAPYDLVRKMRA
HHCCCCCCCCHHHHHHHHHHCCEEEECCCCCHHHCCEEEEEHHHHHHCCCHHHHHHHHHH
SILVLGPMLARMGEATVSLPGGCAIGNRPIDLHLKALEALGAEIEMAQGYVKAVAPDGGL
HHHHHHHHHHHCCCCEEECCCCCEECCCCHHHHHHHHHHCCCHHHHHCCHHEEECCCCCC
PGGKFDFPVVSVGATENAVMAAVLAKGTSHLFNAAREPEIVDLCKLLAAMGAEIEGIGSS
CCCCCCCCEEEECCCCHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHCCCCEECCCCC
DLVIHGVKRLHGATYRVMGDRIEAGSYACAAAITGGDVMLEGANAEEMQATIHALRNIGV
CHHHHHHHHHCCCEEEEECCEECCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCC
TVEETKSGVHIIADGPLKATNLTTAPYPGLATDMQAQLMSLLCKAEGTSVLKETIFENRF
EEEECCCCEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
MHVPELNRMGADIETEGRTAIVKGVETLTGAEVMATDLRASMSLIIAGLAAEGETQVRRI
CCCCCHHHCCCCCCCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
YHLDRGYERLEEKLQLVGADIERVGDD
HHHHHHHHHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure 
TVPVTAPVASAGEWAKRLGMDKLVIRGGNRLSGTIPISGAKNSALTLIPCALLTDEPLT
CCCCCCCCCCHHHHHHHCCCCEEEEECCCEEEEEEEECCCCCCCEEEEEEEHHCCCCCH
LRNLPRLADIDGFQHLMNQFGVMTAVQGKRPEDFGRVMTMEATRITSSVAPYDLVRKMRA
HHCCCCCCCCHHHHHHHHHHCCEEEECCCCCHHHCCEEEEEHHHHHHCCCHHHHHHHHHH
SILVLGPMLARMGEATVSLPGGCAIGNRPIDLHLKALEALGAEIEMAQGYVKAVAPDGGL
HHHHHHHHHHHCCCCEEECCCCCEECCCCHHHHHHHHHHCCCHHHHHCCHHEEECCCCCC
PGGKFDFPVVSVGATENAVMAAVLAKGTSHLFNAAREPEIVDLCKLLAAMGAEIEGIGSS
CCCCCCCCEEEECCCCHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHCCCCEECCCCC
DLVIHGVKRLHGATYRVMGDRIEAGSYACAAAITGGDVMLEGANAEEMQATIHALRNIGV
CHHHHHHHHHCCCEEEEECCEECCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCC
TVEETKSGVHIIADGPLKATNLTTAPYPGLATDMQAQLMSLLCKAEGTSVLKETIFENRF
EEEECCCCEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
MHVPELNRMGADIETEGRTAIVKGVETLTGAEVMATDLRASMSLIIAGLAAEGETQVRRI
CCCCCHHHCCCCCCCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
YHLDRGYERLEEKLQLVGADIERVGDD
HHHHHHHHHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA