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The map label for this gene is yutK [H]

Identifier: 85375064

GI number: 85375064

Start: 2259401

End: 2260750

Strand: Reverse

Name: yutK [H]

Synonym: ELI_11185

Alternate gene names: 85375064

Gene position: 2260750-2259401 (Counterclockwise)

Preceding gene: 85375068

Following gene: 85375063

Centisome position: 74.06

GC content: 64.74

Gene sequence:

>1350_bases
ATGCCGCCCTTCGTCATGAGCCTGGCCGGGATCGCCGCGATCCTTGCCATCGCCTTCCTGCTGTCGACCGGAAAGAAGCG
GATCAAGCTGCGCGTCGTTGGCGCGGCATTCGCGCTGCAGGCGATCATGGCGTTGCTGGTCCTGCGCACGCCGTGGGGCG
TCACCGCGATCCAGTTCCTCTCCGACGGCGTCATCGCGCTGCTCGATTATTCCAAGATCGGGATCGAGGCAATTTTCGGT
CCGATGGGGGACAACCCCTTCACCAACACTTTCGTCATCGCAGCCCTGCCGGTGATCGTGTTCTTCGCCGCAATCGTGTC
GATCCTCTATCACTGGGGCATCATGCAGCGACTGGTGCGCTGGGTCGGCGGGGCGATCGGCTGGATTACCGGCATCAGCA
AGGTCGAGGCACTCGGCAGCGCGGCCAATATCTTCGTCGGCCAGTCCGAAAGCCCGCTGGTAGTGCGGCCCTATCTCGCA
GCGCTGACGCCGAGCCGCCTGTTCACCCTGATGAGCGTCGGCATGGCCGGCGTCGCCGGCACGATCCTCGCCGCCTATGC
CAGTTTTATCGGGGCCGAGGCGGTGCCTTTCCTGCTCGCAGCCGCCTTTATGTCGGCACCTGGCGGGATCCTTATGGCGA
AGATCATCATGCCGGACGATGACAGCGTGCTGGCACGCGACGCGGCCGAACTCTCCGGCGTCGATCCAGAAGGCGAAATC
GTGCTGCCCGCCGCGCGCATCAGCGCCGAAGGGCCCGCGGCCCTGACCGAGAGCGGCAAGCCGCATGAAGTGGAAGTCGC
GGAAACGTTCGAGGAAGGGCACAAACCCGCCAACGTCATCGAAGCCGCTGCGCAAGGCACGCAGACGGGCGTGAAGCTGG
CGGTCGCGGTCGGTGCGATGGTGATGGTCTTCGTGGCGCTGGTAGCGCTGGCCAACGGCATCCTTGGCGGGATCGGCAGT
TGGGTCGGCTATCCCGACGTCAGCTTCCAGCAGCTCATCGGCTATGTCTTCGCGCCGGTCATGTTCCTGATCGGCATCAC
CGACTGGAGCCAGGCGCAGGTTGCCGGCGGCCTGTTCGGCACCAAGATCGTGCTCAACGAATTCGTCGCCTTTATCGACC
TCGGCGCCATGACGGCGGGCGAGTTGACTGACCGTAGCCGCGCTATCGTCACCTTCGCCCTCTGCGGCTTTGCCAACTTC
AGCTCCATTGCGATCCAGATGGCGGTCACCGGCGGTCTTGCGCCGAACCAGAGGCCGGTTATCGCCAAGCTCGGTCTCAG
AGCGCTCGCCGCCGGCTCGCTGGCCAACCTGATGAGTGCCGCCTTGGCGGGCCTGTTCCTCCCTTACTAA

Upstream 100 bases:

>100_bases
CCTAGGGCGATAGCCGCCTCGACCGGACCGGACTCGTTTGACTGCGCGCTCCGGAGCGGCAAAGGGGGGCAGCGAGTCGT
TTGGTTACGAAAGAAACTGC

Downstream 100 bases:

>100_bases
GATAAGTGCCATGACCGACATTGCTTCCGTTTCACTCGACCAGCCGCTCGAAAGCATCGCCGGCGAGCTTGGCGCGTCTT
TCTCCGAATTCGGCTTTGCC

Product: nucleoside permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MPPFVMSLAGIAAILAIAFLLSTGKKRIKLRVVGAAFALQAIMALLVLRTPWGVTAIQFLSDGVIALLDYSKIGIEAIFG
PMGDNPFTNTFVIAALPVIVFFAAIVSILYHWGIMQRLVRWVGGAIGWITGISKVEALGSAANIFVGQSESPLVVRPYLA
ALTPSRLFTLMSVGMAGVAGTILAAYASFIGAEAVPFLLAAAFMSAPGGILMAKIIMPDDDSVLARDAAELSGVDPEGEI
VLPAARISAEGPAALTESGKPHEVEVAETFEEGHKPANVIEAAAQGTQTGVKLAVAVGAMVMVFVALVALANGILGGIGS
WVGYPDVSFQQLIGYVFAPVMFLIGITDWSQAQVAGGLFGTKIVLNEFVAFIDLGAMTAGELTDRSRAIVTFALCGFANF
SSIAIQMAVTGGLAPNQRPVIAKLGLRALAAGSLANLMSAALAGLFLPY

Sequences:

>Translated_449_residues
MPPFVMSLAGIAAILAIAFLLSTGKKRIKLRVVGAAFALQAIMALLVLRTPWGVTAIQFLSDGVIALLDYSKIGIEAIFG
PMGDNPFTNTFVIAALPVIVFFAAIVSILYHWGIMQRLVRWVGGAIGWITGISKVEALGSAANIFVGQSESPLVVRPYLA
ALTPSRLFTLMSVGMAGVAGTILAAYASFIGAEAVPFLLAAAFMSAPGGILMAKIIMPDDDSVLARDAAELSGVDPEGEI
VLPAARISAEGPAALTESGKPHEVEVAETFEEGHKPANVIEAAAQGTQTGVKLAVAVGAMVMVFVALVALANGILGGIGS
WVGYPDVSFQQLIGYVFAPVMFLIGITDWSQAQVAGGLFGTKIVLNEFVAFIDLGAMTAGELTDRSRAIVTFALCGFANF
SSIAIQMAVTGGLAPNQRPVIAKLGLRALAAGSLANLMSAALAGLFLPY
>Mature_448_residues
PPFVMSLAGIAAILAIAFLLSTGKKRIKLRVVGAAFALQAIMALLVLRTPWGVTAIQFLSDGVIALLDYSKIGIEAIFGP
MGDNPFTNTFVIAALPVIVFFAAIVSILYHWGIMQRLVRWVGGAIGWITGISKVEALGSAANIFVGQSESPLVVRPYLAA
LTPSRLFTLMSVGMAGVAGTILAAYASFIGAEAVPFLLAAAFMSAPGGILMAKIIMPDDDSVLARDAAELSGVDPEGEIV
LPAARISAEGPAALTESGKPHEVEVAETFEEGHKPANVIEAAAQGTQTGVKLAVAVGAMVMVFVALVALANGILGGIGSW
VGYPDVSFQQLIGYVFAPVMFLIGITDWSQAQVAGGLFGTKIVLNEFVAFIDLGAMTAGELTDRSRAIVTFALCGFANFS
SIAIQMAVTGGLAPNQRPVIAKLGLRALAAGSLANLMSAALAGLFLPY

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI42542381, Length=466, Percent_Identity=32.8326180257511, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI227116277, Length=466, Percent_Identity=31.1158798283262, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI11545853, Length=461, Percent_Identity=32.3210412147505, Blast_Score=209, Evalue=4e-54,
Organism=Escherichia coli, GI1788485, Length=450, Percent_Identity=39.3333333333333, Blast_Score=261, Evalue=7e-71,
Organism=Escherichia coli, GI1788488, Length=450, Percent_Identity=39.7777777777778, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI1788737, Length=444, Percent_Identity=27.027027027027, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17560276, Length=435, Percent_Identity=31.9540229885057, Blast_Score=215, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI71991794, Length=154, Percent_Identity=44.1558441558442, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25146537, Length=193, Percent_Identity=30.0518134715026, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI45552517, Length=449, Percent_Identity=31.1804008908686, Blast_Score=201, Evalue=6e-52,
Organism=Drosophila melanogaster, GI19921868, Length=449, Percent_Identity=31.1804008908686, Blast_Score=201, Evalue=6e-52,
Organism=Drosophila melanogaster, GI45552519, Length=449, Percent_Identity=31.1804008908686, Blast_Score=201, Evalue=6e-52,
Organism=Drosophila melanogaster, GI281360430, Length=442, Percent_Identity=30.7692307692308, Blast_Score=188, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 46483; Mature: 46352

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPFVMSLAGIAAILAIAFLLSTGKKRIKLRVVGAAFALQAIMALLVLRTPWGVTAIQFL
CCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SDGVIALLDYSKIGIEAIFGPMGDNPFTNTFVIAALPVIVFFAAIVSILYHWGIMQRLVR
HCCCEEEECHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVGGAIGWITGISKVEALGSAANIFVGQSESPLVVRPYLAALTPSRLFTLMSVGMAGVAG
HHCHHHHHHHHHHHHHHHCCHHEEEECCCCCCEEECHHHHHHCHHHHHHHHHHHHHHHHH
TILAAYASFIGAEAVPFLLAAAFMSAPGGILMAKIIMPDDDSVLARDAAELSGVDPEGEI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCE
VLPAARISAEGPAALTESGKPHEVEVAETFEEGHKPANVIEAAAQGTQTGVKLAVAVGAM
EEEHHHHCCCCCCHHCCCCCCCEEHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHH
VMVFVALVALANGILGGIGSWVGYPDVSFQQLIGYVFAPVMFLIGITDWSQAQVAGGLFG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHH
TKIVLNEFVAFIDLGAMTAGELTDRSRAIVTFALCGFANFSSIAIQMAVTGGLAPNQRPV
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHEEEEEEECCCCCCCCCH
IAKLGLRALAAGSLANLMSAALAGLFLPY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PPFVMSLAGIAAILAIAFLLSTGKKRIKLRVVGAAFALQAIMALLVLRTPWGVTAIQFL
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SDGVIALLDYSKIGIEAIFGPMGDNPFTNTFVIAALPVIVFFAAIVSILYHWGIMQRLVR
HCCCEEEECHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVGGAIGWITGISKVEALGSAANIFVGQSESPLVVRPYLAALTPSRLFTLMSVGMAGVAG
HHCHHHHHHHHHHHHHHHCCHHEEEECCCCCCEEECHHHHHHCHHHHHHHHHHHHHHHHH
TILAAYASFIGAEAVPFLLAAAFMSAPGGILMAKIIMPDDDSVLARDAAELSGVDPEGEI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCE
VLPAARISAEGPAALTESGKPHEVEVAETFEEGHKPANVIEAAAQGTQTGVKLAVAVGAM
EEEHHHHCCCCCCHHCCCCCCCEEHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHH
VMVFVALVALANGILGGIGSWVGYPDVSFQQLIGYVFAPVMFLIGITDWSQAQVAGGLFG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHH
TKIVLNEFVAFIDLGAMTAGELTDRSRAIVTFALCGFANFSSIAIQMAVTGGLAPNQRPV
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHEEEEEEECCCCCCCCCH
IAKLGLRALAAGSLANLMSAALAGLFLPY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]