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The map label for this gene is erg3 [H]

Identifier: 85375025

GI number: 85375025

Start: 2221235

End: 2222044

Strand: Reverse

Name: erg3 [H]

Synonym: ELI_10990

Alternate gene names: 85375025

Gene position: 2222044-2221235 (Counterclockwise)

Preceding gene: 85375027

Following gene: 85375022

Centisome position: 72.8

GC content: 64.44

Gene sequence:

>810_bases
ATGCAGGTTTTCGGCCTCGATGCCCCGCTGGCGGCTTTCGCGATCATCGCGGCGACCTTCGTGATTTTCGCGGCGATCGA
GTTCGCCGTGCCGTTCCGCGCGCTGACGCAGTCGAAACCGCGCCGATGGCTGACCAACCTGGCGCTGTTCGCAATCGACA
CACTGGCGCTGCGCCTGCTGGTGCCGGTGGTGCTGGTCGGCATGGCGGCGCTGGCCGAAACGCGCGGCTGGGGGCTTTTC
AATATGCTTGGCTGGCCGGCATGGCTCGAAGTGACGCTGGCGATCCTCGCGCTCGATCTCGCCCTCTACCTCCAGCATTG
GGCGACGCACCGCGTCCCGCTGTTGTGGCGCATGCACCGCGTGCACCATGTCGACCGCGATTTCGATATCACGACCGCCG
CGCGGTTCCATCCGTTCGAGATCCTACTGTCGATGCTCTACAAGCTGGCCATCGTCACGCTGTTGGGCGCCCCGGTACTG
GCGGTGTTCCTGTTCGAAGTGGTCTTCACCATGCTGACGATCTTCAACCATTCGAACACCCGCCTGCCGCAGCGGATCGA
ACCGGCCGTGCGCGCGCTGATCGTCACGCCCGACATGCACCGTGTGCATCATTCGGTGGTCGAGCGGGAGACCAACAGCA
ATTACGGGACGATGCTGTCGCTGTGGGACCGGCTCTTCGGCACCTATCGCGCCGAGCCGGAAGCGGGTCAGGAAGGCGTG
CGGATCGGCCTCGGCGAATATCAGGATGATCAGCCTGCAAGGCTGGGGTGGAGCCTGCTGCTGCCGTTTGTTTCGAACCG
GCGGAGCTAG

Upstream 100 bases:

>100_bases
GGCAGTATAGGGCGCGTGTGCGGCTGCGCAATGTGCGCTCCGGAAGGGGCCTTCCAAAGGCGGTCTTGAAGTGTGCGCCG
GTATCGCCGACTTAACAAAT

Downstream 100 bases:

>100_bases
CCGGCTTTGCCCTTCACCAGCTTGCGTTCGATCGCGGTCCAGAGCGACCTGTAGGCTGGTTGCGCCACACTGGTGGGCGC
GAATTCGCCGACCGGCTGTT

Product: sterol desaturase,-like protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MQVFGLDAPLAAFAIIAATFVIFAAIEFAVPFRALTQSKPRRWLTNLALFAIDTLALRLLVPVVLVGMAALAETRGWGLF
NMLGWPAWLEVTLAILALDLALYLQHWATHRVPLLWRMHRVHHVDRDFDITTAARFHPFEILLSMLYKLAIVTLLGAPVL
AVFLFEVVFTMLTIFNHSNTRLPQRIEPAVRALIVTPDMHRVHHSVVERETNSNYGTMLSLWDRLFGTYRAEPEAGQEGV
RIGLGEYQDDQPARLGWSLLLPFVSNRRS

Sequences:

>Translated_269_residues
MQVFGLDAPLAAFAIIAATFVIFAAIEFAVPFRALTQSKPRRWLTNLALFAIDTLALRLLVPVVLVGMAALAETRGWGLF
NMLGWPAWLEVTLAILALDLALYLQHWATHRVPLLWRMHRVHHVDRDFDITTAARFHPFEILLSMLYKLAIVTLLGAPVL
AVFLFEVVFTMLTIFNHSNTRLPQRIEPAVRALIVTPDMHRVHHSVVERETNSNYGTMLSLWDRLFGTYRAEPEAGQEGV
RIGLGEYQDDQPARLGWSLLLPFVSNRRS
>Mature_269_residues
MQVFGLDAPLAAFAIIAATFVIFAAIEFAVPFRALTQSKPRRWLTNLALFAIDTLALRLLVPVVLVGMAALAETRGWGLF
NMLGWPAWLEVTLAILALDLALYLQHWATHRVPLLWRMHRVHHVDRDFDITTAARFHPFEILLSMLYKLAIVTLLGAPVL
AVFLFEVVFTMLTIFNHSNTRLPQRIEPAVRALIVTPDMHRVHHSVVERETNSNYGTMLSLWDRLFGTYRAEPEAGQEGV
RIGLGEYQDDQPARLGWSLLLPFVSNRRS

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=142, Percent_Identity=30.9859154929577, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 30490; Mature: 30490

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVFGLDAPLAAFAIIAATFVIFAAIEFAVPFRALTQSKPRRWLTNLALFAIDTLALRLL
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VPVVLVGMAALAETRGWGLFNMLGWPAWLEVTLAILALDLALYLQHWATHRVPLLWRMHR
HHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VHHVDRDFDITTAARFHPFEILLSMLYKLAIVTLLGAPVLAVFLFEVVFTMLTIFNHSNT
HHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RLPQRIEPAVRALIVTPDMHRVHHSVVERETNSNYGTMLSLWDRLFGTYRAEPEAGQEGV
CCCHHHHHHHHHHEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
RIGLGEYQDDQPARLGWSLLLPFVSNRRS
EECCCCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQVFGLDAPLAAFAIIAATFVIFAAIEFAVPFRALTQSKPRRWLTNLALFAIDTLALRLL
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VPVVLVGMAALAETRGWGLFNMLGWPAWLEVTLAILALDLALYLQHWATHRVPLLWRMHR
HHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VHHVDRDFDITTAARFHPFEILLSMLYKLAIVTLLGAPVLAVFLFEVVFTMLTIFNHSNT
HHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RLPQRIEPAVRALIVTPDMHRVHHSVVERETNSNYGTMLSLWDRLFGTYRAEPEAGQEGV
CCCHHHHHHHHHHEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
RIGLGEYQDDQPARLGWSLLLPFVSNRRS
EECCCCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]