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The map label for this gene is tauD [H]

Identifier: 85374579

GI number: 85374579

Start: 1785111

End: 1785923

Strand: Reverse

Name: tauD [H]

Synonym: ELI_08760

Alternate gene names: 85374579

Gene position: 1785923-1785111 (Counterclockwise)

Preceding gene: 85374587

Following gene: 85374576

Centisome position: 58.51

GC content: 62.36

Gene sequence:

>813_bases
ATGGCGCCGAAATGCGGCGTCGAAGTTTCCGGCGTCCAGCTCGCCAGCTGCACCGATGCGGAAATGGAAGATATCAAGCA
GTCGATCTACGAACACGGCGTTGCCGTTTTTCGCGACCAGGAATTTTCGCAAGAGGACCATATTCGTTTCGGCAAGCGCT
GGGGCGGGATCGACATCAACAATTACTTCCCGCTCGACGACGATTACGGCGAGATCGCGATCGTCAAGAAAGAGGCGGAT
GAATCGACCAATATCGGCGGGGCGTGGCACACCGACCATTCCTACGACCAGATCCCGGCCATGGGCTCGGTGCTGGTGGC
GCGCGACCTTCCGCCGAGCGGGGGCGATACCGAATGGGCGCATATGGGCGCAGCCTATGATGCGCTGCCCGATGACCTGA
AAGCCGAGATCGAGGGGCTGGAGGCGTTCCACACCGCCGACCATGTCTACAAGACCGACGGCCTCTATGCGCAGACCGAC
ATGGGCAAGAACCTGCGCGGGCAGGATCTGAAGACCGGTGCCGTGCACCCGGTGGTGATCCGCCACCCGCATACGGGCCG
CAAGCTGCTCTATGTAAACAGCGCCTTCACCATCAACATCGTCGGCAAGACGCGCGAGGAAAGCCTGCCGCTGCTCGAAA
AGCTCTACGCCGCCGCGCTGACGGGCGACAACCAGTGCCGCCTGCAATGGAAGCCGGGCACGGTGGCGATCTGGGACAAC
CGCACGACCTGGCACAATGCGATCAACGACTACGCCGGCCACCGCCGCGAGATGCATCGGATAACGTTGTCGGGCGAGGC
GCTGGCGGCCTAA

Upstream 100 bases:

>100_bases
GCGAGGAAATCGCGAGCGCGGATGCGCTTGCGCAAAACAATAACTCCCCGCATAATTGCGCCAGCGGATTGGAGAGGACC
AAACCATGCAAACCACACCG

Downstream 100 bases:

>100_bases
AACGGCAATTCTCGCGATGGCCTGGAGGGGGAGTCTCACCCCAAAGTTCTTGCGGCCCAGATAATCGGCGACAGGGCGAG
GACAGCGAAGCCCGCAGCGA

Product: alpha-ketoglutarate-dependent taurine dioxygenase

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MAPKCGVEVSGVQLASCTDAEMEDIKQSIYEHGVAVFRDQEFSQEDHIRFGKRWGGIDINNYFPLDDDYGEIAIVKKEAD
ESTNIGGAWHTDHSYDQIPAMGSVLVARDLPPSGGDTEWAHMGAAYDALPDDLKAEIEGLEAFHTADHVYKTDGLYAQTD
MGKNLRGQDLKTGAVHPVVIRHPHTGRKLLYVNSAFTINIVGKTREESLPLLEKLYAAALTGDNQCRLQWKPGTVAIWDN
RTTWHNAINDYAGHRREMHRITLSGEALAA

Sequences:

>Translated_270_residues
MAPKCGVEVSGVQLASCTDAEMEDIKQSIYEHGVAVFRDQEFSQEDHIRFGKRWGGIDINNYFPLDDDYGEIAIVKKEAD
ESTNIGGAWHTDHSYDQIPAMGSVLVARDLPPSGGDTEWAHMGAAYDALPDDLKAEIEGLEAFHTADHVYKTDGLYAQTD
MGKNLRGQDLKTGAVHPVVIRHPHTGRKLLYVNSAFTINIVGKTREESLPLLEKLYAAALTGDNQCRLQWKPGTVAIWDN
RTTWHNAINDYAGHRREMHRITLSGEALAA
>Mature_269_residues
APKCGVEVSGVQLASCTDAEMEDIKQSIYEHGVAVFRDQEFSQEDHIRFGKRWGGIDINNYFPLDDDYGEIAIVKKEADE
STNIGGAWHTDHSYDQIPAMGSVLVARDLPPSGGDTEWAHMGAAYDALPDDLKAEIEGLEAFHTADHVYKTDGLYAQTDM
GKNLRGQDLKTGAVHPVVIRHPHTGRKLLYVNSAFTINIVGKTREESLPLLEKLYAAALTGDNQCRLQWKPGTVAIWDNR
TTWHNAINDYAGHRREMHRITLSGEALAA

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=268, Percent_Identity=32.4626865671642, Blast_Score=153, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6322971, Length=279, Percent_Identity=31.8996415770609, Blast_Score=129, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 29959; Mature: 29827

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPKCGVEVSGVQLASCTDAEMEDIKQSIYEHGVAVFRDQEFSQEDHIRFGKRWGGIDIN
CCCCCCCEECCEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHCCCEECCEECC
NYFPLDDDYGEIAIVKKEADESTNIGGAWHTDHSYDQIPAMGSVLVARDLPPSGGDTEWA
CEECCCCCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCEEEEECCCCCCCCCCHH
HMGAAYDALPDDLKAEIEGLEAFHTADHVYKTDGLYAQTDMGKNLRGQDLKTGAVHPVVI
HCCCHHHCCCHHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCCCCCCCCCCCCCEEEE
RHPHTGRKLLYVNSAFTINIVGKTREESLPLLEKLYAAALTGDNQCRLQWKPGTVAIWDN
ECCCCCCEEEEEECEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCEEEEECC
RTTWHNAINDYAGHRREMHRITLSGEALAA
CCHHHHHHHHHHHHHHEEEEEEECCHHHCC
>Mature Secondary Structure 
APKCGVEVSGVQLASCTDAEMEDIKQSIYEHGVAVFRDQEFSQEDHIRFGKRWGGIDIN
CCCCCCEECCEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHCCCEECCEECC
NYFPLDDDYGEIAIVKKEADESTNIGGAWHTDHSYDQIPAMGSVLVARDLPPSGGDTEWA
CEECCCCCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCEEEEECCCCCCCCCCHH
HMGAAYDALPDDLKAEIEGLEAFHTADHVYKTDGLYAQTDMGKNLRGQDLKTGAVHPVVI
HCCCHHHCCCHHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCCCCCCCCCCCCCEEEE
RHPHTGRKLLYVNSAFTINIVGKTREESLPLLEKLYAAALTGDNQCRLQWKPGTVAIWDN
ECCCCCCEEEEEECEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCEEEEECC
RTTWHNAINDYAGHRREMHRITLSGEALAA
CCHHHHHHHHHHHHHHEEEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]