Click here to switch to the map view.

The map label for this gene is ycbL [H]

Identifier: 85374555

GI number: 85374555

Start: 1764186

End: 1764851

Strand: Reverse

Name: ycbL [H]

Synonym: ELI_08640

Alternate gene names: 85374555

Gene position: 1764851-1764186 (Counterclockwise)

Preceding gene: 85374557

Following gene: 85374553

Centisome position: 57.82

GC content: 61.71

Gene sequence:

>666_bases
ATGACCAACACGAAGACTTCTCCGATGAAAGCCGGGATCATTCCCGTCACGCCGCTGCAGCAGAATTGCTCGCTGATCTG
GTGCACAGCGACCAACAAGGGCGCGCTGATCGATCCCGGCGGCGATCTCGACAAGCTCAAGGCCGGGGTGAAAAAGACCG
GGGTCGAGCTGGAAAAGATTCTCATCACCCACGGTCATATCGACCATTGCGGCGAGGCCGGCGTGCTGGCGAAAGAGCTG
GGGCTACCGATCGAAGGTCCTCACGAGGCCGACCGCTTCTGGATCAGCCGCCTGGACGAAGACGGCAAGAAGTACGGGAT
TGCGGGCGAAGTGTTCGAGCCCGATCGCTGGCTCGACGATGGCGATACGGTCACTGTCGGCGAACTCGAACTCGACGTCA
TCCATTGCCCCGGTCACACGCCGGGCCATGTCGTATTCTACCACGCGCCTAGCAAATTCGCCGTCGTGGGCGACGTGCTG
TTCCAAGGCAGCATCGGGCGCACCGATTTCCCGATGGGCAACCACCAGGACCTGATCGATGCCATCACCCAGAAGCTGTG
GCCGCTGGGGAACGACGTGACCTTTATTCCCGGCCACGGCCCCACCAGCACCTTCGGGCAGGAGCGCAAGACCAACGCTT
TCGTCAGCGATTACGCGCTGGGCTGA

Upstream 100 bases:

>100_bases
CCAATATGAACGACGCCTATCTTGCCGGTTGCTTTCGGCAGGGCGAGTATCCGCTGCGGCGAGCCTTGCAATGCCGGGCC
CTGCCCGCCACATCTGCCCC

Downstream 100 bases:

>100_bases
GGCTCGCTAGAGTACCCCGGCGGCGACCAGCGCAGCGACGACACCAAGGCCGAGCAATGTCAGCAACGTAACGATCGTGC
CGATCACGCGGCCGATCTGC

Product: glyoxalase II family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTNTKTSPMKAGIIPVTPLQQNCSLIWCTATNKGALIDPGGDLDKLKAGVKKTGVELEKILITHGHIDHCGEAGVLAKEL
GLPIEGPHEADRFWISRLDEDGKKYGIAGEVFEPDRWLDDGDTVTVGELELDVIHCPGHTPGHVVFYHAPSKFAVVGDVL
FQGSIGRTDFPMGNHQDLIDAITQKLWPLGNDVTFIPGHGPTSTFGQERKTNAFVSDYALG

Sequences:

>Translated_221_residues
MTNTKTSPMKAGIIPVTPLQQNCSLIWCTATNKGALIDPGGDLDKLKAGVKKTGVELEKILITHGHIDHCGEAGVLAKEL
GLPIEGPHEADRFWISRLDEDGKKYGIAGEVFEPDRWLDDGDTVTVGELELDVIHCPGHTPGHVVFYHAPSKFAVVGDVL
FQGSIGRTDFPMGNHQDLIDAITQKLWPLGNDVTFIPGHGPTSTFGQERKTNAFVSDYALG
>Mature_220_residues
TNTKTSPMKAGIIPVTPLQQNCSLIWCTATNKGALIDPGGDLDKLKAGVKKTGVELEKILITHGHIDHCGEAGVLAKELG
LPIEGPHEADRFWISRLDEDGKKYGIAGEVFEPDRWLDDGDTVTVGELELDVIHCPGHTPGHVVFYHAPSKFAVVGDVLF
QGSIGRTDFPMGNHQDLIDAITQKLWPLGNDVTFIPGHGPTSTFGQERKTNAFVSDYALG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=187, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787158, Length=210, Percent_Identity=51.9047619047619, Blast_Score=237, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI17538952, Length=177, Percent_Identity=28.2485875706215, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23891; Mature: 23760

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTKTSPMKAGIIPVTPLQQNCSLIWCTATNKGALIDPGGDLDKLKAGVKKTGVELEKI
CCCCCCCCCCCCCEECCCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHHHHCCCEEEEE
LITHGHIDHCGEAGVLAKELGLPIEGPHEADRFWISRLDEDGKKYGIAGEVFEPDRWLDD
EEECCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCC
GDTVTVGELELDVIHCPGHTPGHVVFYHAPSKFAVVGDVLFQGSIGRTDFPMGNHQDLID
CCEEEEEEEEEEEEECCCCCCCEEEEEECCCCEEEEEHHHCCCCCCCCCCCCCCHHHHHH
AITQKLWPLGNDVTFIPGHGPTSTFGQERKTNAFVSDYALG
HHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure 
TNTKTSPMKAGIIPVTPLQQNCSLIWCTATNKGALIDPGGDLDKLKAGVKKTGVELEKI
CCCCCCCCCCCCEECCCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHHHHCCCEEEEE
LITHGHIDHCGEAGVLAKELGLPIEGPHEADRFWISRLDEDGKKYGIAGEVFEPDRWLDD
EEECCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCC
GDTVTVGELELDVIHCPGHTPGHVVFYHAPSKFAVVGDVLFQGSIGRTDFPMGNHQDLID
CCEEEEEEEEEEEEECCCCCCCEEEEEECCCCEEEEEHHHCCCCCCCCCCCCCCHHHHHH
AITQKLWPLGNDVTFIPGHGPTSTFGQERKTNAFVSDYALG
HHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]