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The map label for this gene is nahD [H]

Identifier: 85374482

GI number: 85374482

Start: 1700995

End: 1701606

Strand: Reverse

Name: nahD [H]

Synonym: ELI_08275

Alternate gene names: 85374482

Gene position: 1701606-1700995 (Counterclockwise)

Preceding gene: 85374485

Following gene: 85374477

Centisome position: 55.75

GC content: 62.25

Gene sequence:

>612_bases
ATGACCAAAACCGTCGAGTTCATCTTCGATTTCGTCAGCCCCAACGGCTATCTTGCATGGTATCCGCTGCGCGATCTCGT
CGCGCGGACCGGGGCGGAACTGGTGGTCACACCGGTATTCCTAGGCGGGATGCATAAGCTGACGGGCAACGCGCCGCCGA
TGATCCGCGACAAGGATGTGAAGGGCAAGGTCGAGTATTCCCTGCTCGAAATGCGTCGCTGGATCGACAGGCACGGCTTC
GACAAATACCGCCTGCACCCGCAATTCCCGTTCAACTCGGTCACTCTCCAGCGCATGCTGCTGGCGGTCGAGGGCGAGGA
ACGGGTCAGGCTGGTCGAGACGCTGCTGCCGATGCTGTGGGAAGAGGGCGTACCGGTTGACGATCCCGCCGCCATCGGCA
GGGGCCTCAGTGATGCCGGCTTCGACGCCGAAGAGCTCCTCGCCAAGACGCAGGATCCGGCGATCAAGCAGCAGCTGGTC
GACAATACACAGTCCGCCGTCGATCGCGGCGCCTTCGGCATCCCGACGTTCTACGTCGACACCGGCGGCGAAGACGAAAT
GTTCTTCGGCAAGGAACGGCTGGTGCAGATCGAGGAAATGCTGGCGGGCTGA

Upstream 100 bases:

>100_bases
ATGCGAACAGTTCTGTCATATATCTGCAACGTTGCGGGGGCGACAAGTTTCCGGCAAGCCGAAAGGGACTTTATAGCTCC
CTTTTCGAAAGGCGACCTGC

Downstream 100 bases:

>100_bases
GCCCTCCGGCCGCGCTCACCGGCTGGCGAGCGTGGGGCTGAAGCCCGAAGTCATCTCGCCCGGCGCAAGGTCGTGATGAG
CGGGACGGGTCACCGGCCTG

Product: hypothetical protein

Products: NA

Alternate protein names: HCCA isomerase [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MTKTVEFIFDFVSPNGYLAWYPLRDLVARTGAELVVTPVFLGGMHKLTGNAPPMIRDKDVKGKVEYSLLEMRRWIDRHGF
DKYRLHPQFPFNSVTLQRMLLAVEGEERVRLVETLLPMLWEEGVPVDDPAAIGRGLSDAGFDAEELLAKTQDPAIKQQLV
DNTQSAVDRGAFGIPTFYVDTGGEDEMFFGKERLVQIEEMLAG

Sequences:

>Translated_203_residues
MTKTVEFIFDFVSPNGYLAWYPLRDLVARTGAELVVTPVFLGGMHKLTGNAPPMIRDKDVKGKVEYSLLEMRRWIDRHGF
DKYRLHPQFPFNSVTLQRMLLAVEGEERVRLVETLLPMLWEEGVPVDDPAAIGRGLSDAGFDAEELLAKTQDPAIKQQLV
DNTQSAVDRGAFGIPTFYVDTGGEDEMFFGKERLVQIEEMLAG
>Mature_202_residues
TKTVEFIFDFVSPNGYLAWYPLRDLVARTGAELVVTPVFLGGMHKLTGNAPPMIRDKDVKGKVEYSLLEMRRWIDRHGFD
KYRLHPQFPFNSVTLQRMLLAVEGEERVRLVETLLPMLWEEGVPVDDPAAIGRGLSDAGFDAEELLAKTQDPAIKQQLVD
NTQSAVDRGAFGIPTFYVDTGGEDEMFFGKERLVQIEEMLAG

Specific function: Catalyzes the isomerization of 2-hydroxychromene-2- carboxylate (HCCA) to trans-O-hydroxybenzylidenepyruvate (THBPA). The reaction is reversible [H]

COG id: COG3917

COG function: function code Q; 2-hydroxychromene-2-carboxylate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7705704, Length=208, Percent_Identity=28.3653846153846, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI219842333, Length=205, Percent_Identity=28.2926829268293, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR014440
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA [H]

EC number: NA

Molecular weight: Translated: 22880; Mature: 22748

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTVEFIFDFVSPNGYLAWYPLRDLVARTGAELVVTPVFLGGMHKLTGNAPPMIRDKDV
CCCHHHHHHHHCCCCCEEEEECHHHHHHHCCCCEEEHHHHHCCHHHHCCCCCCCCCCCCC
KGKVEYSLLEMRRWIDRHGFDKYRLHPQFPFNSVTLQRMLLAVEGEERVRLVETLLPMLW
CCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EEGVPVDDPAAIGRGLSDAGFDAEELLAKTQDPAIKQQLVDNTQSAVDRGAFGIPTFYVD
HCCCCCCCHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEE
TGGEDEMFFGKERLVQIEEMLAG
CCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKTVEFIFDFVSPNGYLAWYPLRDLVARTGAELVVTPVFLGGMHKLTGNAPPMIRDKDV
CCHHHHHHHHCCCCCEEEEECHHHHHHHCCCCEEEHHHHHCCHHHHCCCCCCCCCCCCC
KGKVEYSLLEMRRWIDRHGFDKYRLHPQFPFNSVTLQRMLLAVEGEERVRLVETLLPMLW
CCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EEGVPVDDPAAIGRGLSDAGFDAEELLAKTQDPAIKQQLVDNTQSAVDRGAFGIPTFYVD
HCCCCCCCHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEE
TGGEDEMFFGKERLVQIEEMLAG
CCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002605; 1447127 [H]