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The map label for this gene is lolC [H]

Identifier: 85374229

GI number: 85374229

Start: 1453089

End: 1454336

Strand: Reverse

Name: lolC [H]

Synonym: ELI_07010

Alternate gene names: 85374229

Gene position: 1454336-1453089 (Counterclockwise)

Preceding gene: 85374233

Following gene: 85374228

Centisome position: 47.65

GC content: 62.1

Gene sequence:

>1248_bases
ATGCCTTTGCTGCTCAGCCCCTTCGAATGGACCATCGCCAAGCGTTACCTGCTACCCGGCAGGGGCGAGGCATTCATCGC
GCTCGTCGCCGGGATCAGCGTCGGCGTCGTGATGCTGTCGGTCGCCATGCTGGTGATCGTGATGAGCGTGATGAACGGCT
TCCGCGCCGAGCTGCTCGACAAGATCGTCGGCGTGAATGGCCATGCGATCGTACAGGCCTATGGCGGCCGTCTCGACAAT
TGGGAAAGCATTCTCGAGGAAGTGCGCGATACGCCCGGCGTCACCGAAGCCTCGCCGCTGATCGAACAGCCCCTGCTGGT
GACTTTCAACGGCCGGGTCGAGGCCGTCTTCGTGCGCGGCAACACGCAGGAGGATATCGCCGAACTGTCCGACAAGGTCG
TGCTCGGCAACCTGCAGCGACTGCAGCCCGAGGCGAGCGTCGTGGCGATAGGGGCGCGGCTGGCCGAGAACATCGGCGCG
CGGGTTGGCGATGTGGTGACGATCATCAATCCCGCAGGGCGCTCCACGCCCTTCGGCACAGTGCCGCGGCAGGTCGGCTA
CGAGGTCGCTGCCATCTTCGAGGTCGGGCTCTACGACTACGACCAGGCCTTCATGGTCATGCCGATCCCCGACGCGCAGA
CGCTGCTGCTGACCGGCGACACCATCGGCATGATCGAAGTGAAGACCGAAGATGCCGACAATGTGGCGGAAATCATGGCT
CCGGTAGAGGCAAAACTTTCCGGAATAGCCCAGGTTCGCACATGGCAGCAGATCAACAGCTCGATCTTCGAAGCCTTGCA
GGTCGAGCGGGTGGCGATGTTCTTCGCGCTCAGCTTCATGGTGCTGGTGGCGGCGTTCAATATCCTCTCGAGCCTCGTGA
TGCTGGTGCGCGCAAAAACTCGCGATATCGCCATCATGCGAACCATGGGCGCGACGCGAAAATCGCTGCTCAAGATTTTC
GTGACGACCGGTTTCACGGTCGGCGCGATCGGAACCTTTGCGGGGCTCCTGCTGGGAACGATTGTGCTCTATTTCCGCGA
ACCGATCGTCGATGTGATCGCGTTCGTGACGGGTCAGGAATTGTGGGACCCCGAAGTCCGCTTCCTCTCGACGCTTCCGG
CGAAGGCCGATCCGGTCGAGATCATCGGCATCGTGGTTCTCGCGCTGGTGCTGAGCTTCCTCGCGACGCTTTACCCCGCG
CTCAAGGCTTCGGGCACCGATCCGGTTCAGGTGCTGCGCTATGAGTAA

Upstream 100 bases:

>100_bases
GGGCGAAGAACCGCAATCCTTACCCGGTTATAACCTTCGCGGATTTCATTGCGCAGACAGGAAGGGATTTCTAAGGCGTG
GGCACAAGCAACCAATCGGA

Downstream 100 bases:

>100_bases
GGCTGTCGTCGAATTGCGCGGTGTGACCCGCAGCTTCGAGCAAGGCGGCACCCGGATCGACGTGCTGCGTGGTATCGACC
TGGCGGTGCAGCCGGGCGAG

Product: ABC-type transport system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MPLLLSPFEWTIAKRYLLPGRGEAFIALVAGISVGVVMLSVAMLVIVMSVMNGFRAELLDKIVGVNGHAIVQAYGGRLDN
WESILEEVRDTPGVTEASPLIEQPLLVTFNGRVEAVFVRGNTQEDIAELSDKVVLGNLQRLQPEASVVAIGARLAENIGA
RVGDVVTIINPAGRSTPFGTVPRQVGYEVAAIFEVGLYDYDQAFMVMPIPDAQTLLLTGDTIGMIEVKTEDADNVAEIMA
PVEAKLSGIAQVRTWQQINSSIFEALQVERVAMFFALSFMVLVAAFNILSSLVMLVRAKTRDIAIMRTMGATRKSLLKIF
VTTGFTVGAIGTFAGLLLGTIVLYFREPIVDVIAFVTGQELWDPEVRFLSTLPAKADPVEIIGIVVLALVLSFLATLYPA
LKASGTDPVQVLRYE

Sequences:

>Translated_415_residues
MPLLLSPFEWTIAKRYLLPGRGEAFIALVAGISVGVVMLSVAMLVIVMSVMNGFRAELLDKIVGVNGHAIVQAYGGRLDN
WESILEEVRDTPGVTEASPLIEQPLLVTFNGRVEAVFVRGNTQEDIAELSDKVVLGNLQRLQPEASVVAIGARLAENIGA
RVGDVVTIINPAGRSTPFGTVPRQVGYEVAAIFEVGLYDYDQAFMVMPIPDAQTLLLTGDTIGMIEVKTEDADNVAEIMA
PVEAKLSGIAQVRTWQQINSSIFEALQVERVAMFFALSFMVLVAAFNILSSLVMLVRAKTRDIAIMRTMGATRKSLLKIF
VTTGFTVGAIGTFAGLLLGTIVLYFREPIVDVIAFVTGQELWDPEVRFLSTLPAKADPVEIIGIVVLALVLSFLATLYPA
LKASGTDPVQVLRYE
>Mature_414_residues
PLLLSPFEWTIAKRYLLPGRGEAFIALVAGISVGVVMLSVAMLVIVMSVMNGFRAELLDKIVGVNGHAIVQAYGGRLDNW
ESILEEVRDTPGVTEASPLIEQPLLVTFNGRVEAVFVRGNTQEDIAELSDKVVLGNLQRLQPEASVVAIGARLAENIGAR
VGDVVTIINPAGRSTPFGTVPRQVGYEVAAIFEVGLYDYDQAFMVMPIPDAQTLLLTGDTIGMIEVKTEDADNVAEIMAP
VEAKLSGIAQVRTWQQINSSIFEALQVERVAMFFALSFMVLVAAFNILSSLVMLVRAKTRDIAIMRTMGATRKSLLKIFV
TTGFTVGAIGTFAGLLLGTIVLYFREPIVDVIAFVTGQELWDPEVRFLSTLPAKADPVEIIGIVVLALVLSFLATLYPAL
KASGTDPVQVLRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=409, Percent_Identity=29.5843520782396, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI1787360, Length=419, Percent_Identity=27.4463007159904, Blast_Score=125, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44914; Mature: 44783

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLLSPFEWTIAKRYLLPGRGEAFIALVAGISVGVVMLSVAMLVIVMSVMNGFRAELLD
CCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIVGVNGHAIVQAYGGRLDNWESILEEVRDTPGVTEASPLIEQPLLVTFNGRVEAVFVRG
HHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCEEEEECCCEEEEEEEC
NTQEDIAELSDKVVLGNLQRLQPEASVVAIGARLAENIGARVGDVVTIINPAGRSTPFGT
CCHHHHHHHHCHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
VPRQVGYEVAAIFEVGLYDYDQAFMVMPIPDAQTLLLTGDTIGMIEVKTEDADNVAEIMA
CCHHHCHHHHHHHHHCCEECCCCEEEEECCCCCEEEEECCCEEEEEEECCCCCHHHHHHH
PVEAKLSGIAQVRTWQQINSSIFEALQVERVAMFFALSFMVLVAAFNILSSLVMLVRAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RDIAIMRTMGATRKSLLKIFVTTGFTVGAIGTFAGLLLGTIVLYFREPIVDVIAFVTGQE
CCCHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LWDPEVRFLSTLPAKADPVEIIGIVVLALVLSFLATLYPALKASGTDPVQVLRYE
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
>Mature Secondary Structure 
PLLLSPFEWTIAKRYLLPGRGEAFIALVAGISVGVVMLSVAMLVIVMSVMNGFRAELLD
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIVGVNGHAIVQAYGGRLDNWESILEEVRDTPGVTEASPLIEQPLLVTFNGRVEAVFVRG
HHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCEEEEECCCEEEEEEEC
NTQEDIAELSDKVVLGNLQRLQPEASVVAIGARLAENIGARVGDVVTIINPAGRSTPFGT
CCHHHHHHHHCHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
VPRQVGYEVAAIFEVGLYDYDQAFMVMPIPDAQTLLLTGDTIGMIEVKTEDADNVAEIMA
CCHHHCHHHHHHHHHCCEECCCCEEEEECCCCCEEEEECCCEEEEEEECCCCCHHHHHHH
PVEAKLSGIAQVRTWQQINSSIFEALQVERVAMFFALSFMVLVAAFNILSSLVMLVRAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RDIAIMRTMGATRKSLLKIFVTTGFTVGAIGTFAGLLLGTIVLYFREPIVDVIAFVTGQE
CCCHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LWDPEVRFLSTLPAKADPVEIIGIVVLALVLSFLATLYPALKASGTDPVQVLRYE
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]