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The map label for this gene is ntrY [H]

Identifier: 85374081

GI number: 85374081

Start: 1303129

End: 1305348

Strand: Reverse

Name: ntrY [H]

Synonym: ELI_06270

Alternate gene names: 85374081

Gene position: 1305348-1303129 (Counterclockwise)

Preceding gene: 85374082

Following gene: 85374080

Centisome position: 42.76

GC content: 63.83

Gene sequence:

>2220_bases
ATGCAGGACGGGGACCAGACAGTTCAGCGCAGCCCGCGCTGGTGGCGACAATTCGTCGTCGCGTCGCGCCGCGCCAACCT
GTTCCGCTATCTCGAACTAGCCTGCCTGCTGGGCGTGATCGGCATGATCGCGCTGACCTATGCCACGTTCACCGGTGCTC
CGCCCGACGGGCAGTTGCTGCCGACCCAGCAGGTCACGAGCCTGCTGGTGGGTACGCTGGTGCCATCGATCGCATTGCTG
GTCCTTCTGGGCAGGCGGCTAGCATTGCGCCGCGCGGCGGGCAGTACCGCACGGTTGCACGTGCGACTGGTGGCGCTGTT
CTCGATCATCGCCGCCGTGCCGACGCTTATGGTGGCAGGCTTCGCGGCCTTCCTGTTCCAGTCGGGCGTGGATTTCTGGT
TCTCCGGCCAGTCGCGCGGGATGATGGATAACGTCAACAGTCTCGCCGAAGGCTATTTCGAGCAGAACCAGCTCGACGTC
GCGCAGCAAACGCAGGCGATGGCGAGCGACATGCTGTTCCTGCTCGAAGGGCGCGATGCAGAAGACCTGACGAGCGAGGA
GTTTCTGGAGGATTACACCTACCATATGCAGGCGCGCGAGCTGAACGAGTCCGCGATCATGCAGGTATTTTCCGACGGAC
GCATCAACACCGCGTTTGCGTACGGCCTGGTCGAAGGCAACGATCCTGCCGAAGCGACGGCAGATGCGCTGGAGATCTAT
CGCCGCGGTGAAACGCAGGCGGTGTTCGCCAATGGCCAGCGGATAGAAGCGGTATTCCCGATCGACCGGCAGGCGGGTGT
CTATCTCTACAACGCGCGGACGTCGGAATCGGCGGCGTTCAGCCAGTGGGAGCAGGCGAGCGACGTGGTCGCATCGTATC
AGCAACTGACGACGCGGGCGCGCGCGTTGCAATTGCGGTTCAACCTGGCGCTGTTCTTCGTTTCGCTGTCGCTGGTCGGG
CTGGCAGTGTGGTTTGCGCTGCGCTTCGCGGACCGTCAGGTCGAGCCGTTGACGGACCTTGTTGCCGCTGCACGCAAGGT
CGGCGCGGGGAATTTCGCGCTGCGTGTCGAAGGGCGTACCGGGGCGGACGAAATCGGCCTGCTCAATCGGGCCTTCAACC
GAATGACGGCTCAGCTCGAAAAGCAGACCGATGCACTCGTGTCTGCGAACCAGCAGCTCGGCGACCGGCGCGCCTTCATC
GAAACGGTGCTCGAATCCGTGACGGCGGGCGTCATCTCGACCGACGCCAGTGGCAAGGTCCTGCTGATGAACTCGTCGGC
GCAGAGCCTTTTGCTGGAGGACCCGGACACCGCCGTCCGCGGCGAGGCGCTGGAGGAATTTGCGCCTGAGATGGCCAAGC
TGGCGCAGGCCGGTGTCGAAAAGGGCATCATTAACGTGTCGAACGGTGCCGAGCTTTTGACGCTGGCCGTCAAGCTCGCG
CCCGCATCCGGCGGCCACGTGATCACGTTCGAGGACATCACCCGCCAGTTGCTCGATCAGCGTCAGGCGGCATGGTCCGA
CGTGGCGCGCCGCATTGCGCACGAAATCAAGAACCCGCTCACGCCGATCCAGCTTGCCACGGAGCGCTTGAAGCGTCGCT
ATCGCAAGCAGATCGAGGCCGATGGCGAATTGTTCGACGAACTCACATCCACCATTGTCCGGCAGGTCGGGGCCCTGCGG
ACCATGGTCGACGAATTTTCGTCCTTCGCGCGGTTGCCGAAACCGGTGTTCCGGCCCGAAGATGCGCTCGACCTGTTGCG
GCAATCCCTGTTTTTGCAGGAAGTCGGCCATCCCTCGATCGACTTCGCGCTCAACCAGCAGGTCGAAGGGCCGCTCGTAA
TCGAGTGCGATCGCCACCAGTTCGGACAGGCGCTGACCAATGTGCTCAAGAATGCCGCCGAAGCGGTAGATGCGCGGGCG
AAGATGGCCGATGTTGACTTTCGCGGCCGCATCGCCGTCACGATCTCGGCAGACGATGAAGGTATCGAAATCGCTGTCGA
GGACAACGGGGTCGGCCTGCCGCAGGACCGCGAGCGGATCGTCGAACCCTATATGACCACGCGCGAGCAGGGCACAGGGC
TCGGCCTGGCGATCGTCAACAAGATCGTCGAGGAGCATGGGGGCGACATGAGTTTCGCGGCCGCCGAAAACGGCGGGACC
TGCGTCACGCTGCGCTTCGCGCGCCGTCCCTCCGTGCCGGAAAGCGAGGCCGCCGAATGA

Upstream 100 bases:

>100_bases
TCGGTATCGTCGCCGAGACGTTCTCTCCACGGGGCTAGTTGCAGAAAAGCAACAAATTTCGCTTGCATATGGGCAACACC
GTCGTTGTAACTGCGCAACG

Downstream 100 bases:

>100_bases
TGCGCACATATCCCGAGCTTGAAAATGAGGAGACGCTGTAATGGCGCTCGATATCCTGGTCGTCGACGATGAACGCGATA
TTCGCGAACTGGTGTCCGGC

Product: two-component signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 739; Mature: 739

Protein sequence:

>739_residues
MQDGDQTVQRSPRWWRQFVVASRRANLFRYLELACLLGVIGMIALTYATFTGAPPDGQLLPTQQVTSLLVGTLVPSIALL
VLLGRRLALRRAAGSTARLHVRLVALFSIIAAVPTLMVAGFAAFLFQSGVDFWFSGQSRGMMDNVNSLAEGYFEQNQLDV
AQQTQAMASDMLFLLEGRDAEDLTSEEFLEDYTYHMQARELNESAIMQVFSDGRINTAFAYGLVEGNDPAEATADALEIY
RRGETQAVFANGQRIEAVFPIDRQAGVYLYNARTSESAAFSQWEQASDVVASYQQLTTRARALQLRFNLALFFVSLSLVG
LAVWFALRFADRQVEPLTDLVAAARKVGAGNFALRVEGRTGADEIGLLNRAFNRMTAQLEKQTDALVSANQQLGDRRAFI
ETVLESVTAGVISTDASGKVLLMNSSAQSLLLEDPDTAVRGEALEEFAPEMAKLAQAGVEKGIINVSNGAELLTLAVKLA
PASGGHVITFEDITRQLLDQRQAAWSDVARRIAHEIKNPLTPIQLATERLKRRYRKQIEADGELFDELTSTIVRQVGALR
TMVDEFSSFARLPKPVFRPEDALDLLRQSLFLQEVGHPSIDFALNQQVEGPLVIECDRHQFGQALTNVLKNAAEAVDARA
KMADVDFRGRIAVTISADDEGIEIAVEDNGVGLPQDRERIVEPYMTTREQGTGLGLAIVNKIVEEHGGDMSFAAAENGGT
CVTLRFARRPSVPESEAAE

Sequences:

>Translated_739_residues
MQDGDQTVQRSPRWWRQFVVASRRANLFRYLELACLLGVIGMIALTYATFTGAPPDGQLLPTQQVTSLLVGTLVPSIALL
VLLGRRLALRRAAGSTARLHVRLVALFSIIAAVPTLMVAGFAAFLFQSGVDFWFSGQSRGMMDNVNSLAEGYFEQNQLDV
AQQTQAMASDMLFLLEGRDAEDLTSEEFLEDYTYHMQARELNESAIMQVFSDGRINTAFAYGLVEGNDPAEATADALEIY
RRGETQAVFANGQRIEAVFPIDRQAGVYLYNARTSESAAFSQWEQASDVVASYQQLTTRARALQLRFNLALFFVSLSLVG
LAVWFALRFADRQVEPLTDLVAAARKVGAGNFALRVEGRTGADEIGLLNRAFNRMTAQLEKQTDALVSANQQLGDRRAFI
ETVLESVTAGVISTDASGKVLLMNSSAQSLLLEDPDTAVRGEALEEFAPEMAKLAQAGVEKGIINVSNGAELLTLAVKLA
PASGGHVITFEDITRQLLDQRQAAWSDVARRIAHEIKNPLTPIQLATERLKRRYRKQIEADGELFDELTSTIVRQVGALR
TMVDEFSSFARLPKPVFRPEDALDLLRQSLFLQEVGHPSIDFALNQQVEGPLVIECDRHQFGQALTNVLKNAAEAVDARA
KMADVDFRGRIAVTISADDEGIEIAVEDNGVGLPQDRERIVEPYMTTREQGTGLGLAIVNKIVEEHGGDMSFAAAENGGT
CVTLRFARRPSVPESEAAE
>Mature_739_residues
MQDGDQTVQRSPRWWRQFVVASRRANLFRYLELACLLGVIGMIALTYATFTGAPPDGQLLPTQQVTSLLVGTLVPSIALL
VLLGRRLALRRAAGSTARLHVRLVALFSIIAAVPTLMVAGFAAFLFQSGVDFWFSGQSRGMMDNVNSLAEGYFEQNQLDV
AQQTQAMASDMLFLLEGRDAEDLTSEEFLEDYTYHMQARELNESAIMQVFSDGRINTAFAYGLVEGNDPAEATADALEIY
RRGETQAVFANGQRIEAVFPIDRQAGVYLYNARTSESAAFSQWEQASDVVASYQQLTTRARALQLRFNLALFFVSLSLVG
LAVWFALRFADRQVEPLTDLVAAARKVGAGNFALRVEGRTGADEIGLLNRAFNRMTAQLEKQTDALVSANQQLGDRRAFI
ETVLESVTAGVISTDASGKVLLMNSSAQSLLLEDPDTAVRGEALEEFAPEMAKLAQAGVEKGIINVSNGAELLTLAVKLA
PASGGHVITFEDITRQLLDQRQAAWSDVARRIAHEIKNPLTPIQLATERLKRRYRKQIEADGELFDELTSTIVRQVGALR
TMVDEFSSFARLPKPVFRPEDALDLLRQSLFLQEVGHPSIDFALNQQVEGPLVIECDRHQFGQALTNVLKNAAEAVDARA
KMADVDFRGRIAVTISADDEGIEIAVEDNGVGLPQDRERIVEPYMTTREQGTGLGLAIVNKIVEEHGGDMSFAAAENGGT
CVTLRFARRPSVPESEAAE

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=366, Percent_Identity=25.1366120218579, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=30.8333333333333, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789808, Length=236, Percent_Identity=27.1186440677966, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81031; Mature: 81031

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDGDQTVQRSPRWWRQFVVASRRANLFRYLELACLLGVIGMIALTYATFTGAPPDGQLL
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PTQQVTSLLVGTLVPSIALLVLLGRRLALRRAAGSTARLHVRLVALFSIIAAVPTLMVAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FAAFLFQSGVDFWFSGQSRGMMDNVNSLAEGYFEQNQLDVAQQTQAMASDMLFLLEGRDA
HHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
EDLTSEEFLEDYTYHMQARELNESAIMQVFSDGRINTAFAYGLVEGNDPAEATADALEIY
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHH
RRGETQAVFANGQRIEAVFPIDRQAGVYLYNARTSESAAFSQWEQASDVVASYQQLTTRA
HCCCCEEEEECCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RALQLRFNLALFFVSLSLVGLAVWFALRFADRQVEPLTDLVAAARKVGAGNFALRVEGRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCC
GADEIGLLNRAFNRMTAQLEKQTDALVSANQQLGDRRAFIETVLESVTAGVISTDASGKV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEE
LLMNSSAQSLLLEDPDTAVRGEALEEFAPEMAKLAQAGVEKGIINVSNGAELLTLAVKLA
EEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHEEHEEEEEE
PASGGHVITFEDITRQLLDQRQAAWSDVARRIAHEIKNPLTPIQLATERLKRRYRKQIEA
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
DGELFDELTSTIVRQVGALRTMVDEFSSFARLPKPVFRPEDALDLLRQSLFLQEVGHPSI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
DFALNQQVEGPLVIECDRHQFGQALTNVLKNAAEAVDARAKMADVDFRGRIAVTISADDE
CHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCC
GIEIAVEDNGVGLPQDRERIVEPYMTTREQGTGLGLAIVNKIVEEHGGDMSFAAAENGGT
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCE
CVTLRFARRPSVPESEAAE
EEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MQDGDQTVQRSPRWWRQFVVASRRANLFRYLELACLLGVIGMIALTYATFTGAPPDGQLL
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PTQQVTSLLVGTLVPSIALLVLLGRRLALRRAAGSTARLHVRLVALFSIIAAVPTLMVAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FAAFLFQSGVDFWFSGQSRGMMDNVNSLAEGYFEQNQLDVAQQTQAMASDMLFLLEGRDA
HHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
EDLTSEEFLEDYTYHMQARELNESAIMQVFSDGRINTAFAYGLVEGNDPAEATADALEIY
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHH
RRGETQAVFANGQRIEAVFPIDRQAGVYLYNARTSESAAFSQWEQASDVVASYQQLTTRA
HCCCCEEEEECCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RALQLRFNLALFFVSLSLVGLAVWFALRFADRQVEPLTDLVAAARKVGAGNFALRVEGRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCC
GADEIGLLNRAFNRMTAQLEKQTDALVSANQQLGDRRAFIETVLESVTAGVISTDASGKV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEE
LLMNSSAQSLLLEDPDTAVRGEALEEFAPEMAKLAQAGVEKGIINVSNGAELLTLAVKLA
EEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHEEHEEEEEE
PASGGHVITFEDITRQLLDQRQAAWSDVARRIAHEIKNPLTPIQLATERLKRRYRKQIEA
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
DGELFDELTSTIVRQVGALRTMVDEFSSFARLPKPVFRPEDALDLLRQSLFLQEVGHPSI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
DFALNQQVEGPLVIECDRHQFGQALTNVLKNAAEAVDARAKMADVDFRGRIAVTISADDE
CHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCC
GIEIAVEDNGVGLPQDRERIVEPYMTTREQGTGLGLAIVNKIVEEHGGDMSFAAAENGGT
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCE
CVTLRFARRPSVPESEAAE
EEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]