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The map label for this gene is torS [H]

Identifier: 85373891

GI number: 85373891

Start: 1099355

End: 1101460

Strand: Direct

Name: torS [H]

Synonym: ELI_05320

Alternate gene names: 85373891

Gene position: 1099355-1101460 (Clockwise)

Preceding gene: 85373890

Following gene: 85373892

Centisome position: 36.02

GC content: 62.96

Gene sequence:

>2106_bases
ATGATGACGGGCTCCGGCTTGTGGGCATTTCTCGTCATGCTGGTGCACTTGCTGAGTGCGGCGGGTTGCATCGTGGCGGC
CGCCTGGGTGATCAAGCGCCCGCTTGCCAAACGGCCCGATCGCAAGCCTACGATCGCTGCTTTCGCCCTCACGACAATTT
GGGCGATCATCGCCGCCTCGCTCGGTGCGCAATCGGACCCGGCCGTGTTGGCGGAGACTGGTCGCAATCTCGCCTGGATC
CTCGTCTTGTACCGCTTGTTCGGTCACGACGGCCGCGACCGTGGCATGACCGGCATCAGGCCCGTTGCGCTCGCCCTGGC
GTTCGTATCCCTGATGCAGCCGGTTCTCCTCTTCGTCGCGGCAAATTGGGCGATCACCCCCGAATTGCAGGAGGCTACGG
CGCAAACTGCTGCCGCGCTCCATATGCTCGTGGCCATCGGCGCGCTTGTTTTGCTGCATAACCTCTATGCCGGCGCCGCT
CCCGATACGCGGGTTACGCTGCGATGGAGTGCGGCCGGTCTGACCGGGTTCTGGGCGGTCGAACTGAATTATTTCGTGTT
CGCATATCTGGTCGGTCAGGCGCCGCCGGAGTTCGCCGCCATCCGCGGACTGGTCGCGGGTTTGATGGCTATCCCGCTCG
CGCTAGGGGCATCGAACGGTCTTGCCGGGCGCAGGTTGCAGGCCAGCCATACAGTCGCATTCAGAACGCTGTCGCTGCTG
GTGATTGGCGCCTACCTCGGCTTGGTTGTGATCGCGGCCGAACTGGTTTCGCTGCTTGGCGGCGATCTGGGCCGTCTGGC
GCAGGTCGGTTTCCTGGTCGTGGCGGCGGCTGTCACGCTGCTCTGGTTGCCGTCCGAGCGCCTGCGCGCATGGGTTCGCG
TTACCGTGCTCAAGCACCTCTTCAAGCACCGCTATGACTATCGCGAAGAGTGGATGCGGTTTACCGAGACGATCGGCCGG
GCAAACGACCGGGATCTCCCGCTCTTCCAGCGTGCGGCCAAGGCGATGGCCGATATCATCCAGAGCCCGGGCGCAGTGTT
GTTCCTGCCGGACGACGACGGTCGCATGATCGAACAGTCACGCTGGAACTGGACCGGAGCGGACCAGAGCCTTGCAGCGC
TCTCGCCGGATTTCGTCACGCGCCTCGCGCGCGAAGAATTCATTGTCGAAATTGGTCATCAGCGTCCGAGCGGCGATCCC
CGTTACCCGCAGGTCCCGGCCGAGCTTGAAGCAGACCCCAAGGCTTGGGTCATCATTCCCTTGCTGCATTTCGACCGCAA
CGTCGGCGTGGTCCTGCTCGAACGGCCGAATGTGCCCCGGTCGCTCGACTGGGAAGACTTTGACCTGCTCAAGATCGCGG
CGCGGCAACTGGCGAGTTACCTTGCCGAGCACGAAAGCCAGAACGCGCTGATGGAAGCCGCACAGTTCGACGATTTCAAT
CGCCGCATGGCGTTTGTGATGCACGACATCAAGAACCTGGCGAGCCAGCTGCAATTGCTGAGCAAGAATGCCGAAAAGCA
CTCTGAAAACCCCGACTTCCGAAAGGACATGCTCGTAACCTTATCGAGCAGCGCAGGAAAATTGAACCAGTTGCTTGCGC
GGCTCGGTCGCTATGGCACGGGGCAGCCGGTCGTCCCCAGGCCCGTCGATCTGAGCGCCCTTGCGCGCGGCGTGGTGCGT
CGCTTCGAGGCCGACCATCCGGTTGCGCTCACCCGCGCCGATGCATGCAGCGTGCTCGCGGATATGGAGTGCCTCGAGCA
GGCTGTTGTCCACCTGGTGCAAAACGCGATCGATGCGAGCGATCCGGGCATGCCGGTTTCGGTCGATGTTTCGAGCGATG
GCCTCCACGGCAAGATCGAAATTGTCGACAGTGGTTGCGGCATGGATCCGGAGTTCGTCCGCCACCGCCTCTTCAAGCCG
TTCGTTTCTTCGAAAGAGGGCGGCTTCGGGATCGGCGCACTTGAGGCGCGCGAACTGGTCCGGGCCATGCAGGGCCGTCT
CGATGTCCAGTCGCGCCCCGGTATCGGCTCGCGCTTCTCCATCACTTTGCCGCTTGCCGAAGCGGCGAGGTTCCTCTCCT
CCAATAATGACCAAGAGGCTGCCTGA

Upstream 100 bases:

>100_bases
TCGAATACGATCTCTACTACGCGAAGAATTACACGCCGTTCCTGGATCTGCTGATTCTGCTTCAGACGCTCAGGGTGATC
CTGTGGCCGGACGGTGCGCG

Downstream 100 bases:

>100_bases
TGGCCCAGAACCGACCCAAACTGCTCGTGATTGAGGACGATCCCGGCCTGCAGGCCCAGCTCAAATGGGCTTACGAGGAC
TTCGAGGTCGTCATTGCCGG

Product: sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MMTGSGLWAFLVMLVHLLSAAGCIVAAAWVIKRPLAKRPDRKPTIAAFALTTIWAIIAASLGAQSDPAVLAETGRNLAWI
LVLYRLFGHDGRDRGMTGIRPVALALAFVSLMQPVLLFVAANWAITPELQEATAQTAAALHMLVAIGALVLLHNLYAGAA
PDTRVTLRWSAAGLTGFWAVELNYFVFAYLVGQAPPEFAAIRGLVAGLMAIPLALGASNGLAGRRLQASHTVAFRTLSLL
VIGAYLGLVVIAAELVSLLGGDLGRLAQVGFLVVAAAVTLLWLPSERLRAWVRVTVLKHLFKHRYDYREEWMRFTETIGR
ANDRDLPLFQRAAKAMADIIQSPGAVLFLPDDDGRMIEQSRWNWTGADQSLAALSPDFVTRLAREEFIVEIGHQRPSGDP
RYPQVPAELEADPKAWVIIPLLHFDRNVGVVLLERPNVPRSLDWEDFDLLKIAARQLASYLAEHESQNALMEAAQFDDFN
RRMAFVMHDIKNLASQLQLLSKNAEKHSENPDFRKDMLVTLSSSAGKLNQLLARLGRYGTGQPVVPRPVDLSALARGVVR
RFEADHPVALTRADACSVLADMECLEQAVVHLVQNAIDASDPGMPVSVDVSSDGLHGKIEIVDSGCGMDPEFVRHRLFKP
FVSSKEGGFGIGALEARELVRAMQGRLDVQSRPGIGSRFSITLPLAEAARFLSSNNDQEAA

Sequences:

>Translated_701_residues
MMTGSGLWAFLVMLVHLLSAAGCIVAAAWVIKRPLAKRPDRKPTIAAFALTTIWAIIAASLGAQSDPAVLAETGRNLAWI
LVLYRLFGHDGRDRGMTGIRPVALALAFVSLMQPVLLFVAANWAITPELQEATAQTAAALHMLVAIGALVLLHNLYAGAA
PDTRVTLRWSAAGLTGFWAVELNYFVFAYLVGQAPPEFAAIRGLVAGLMAIPLALGASNGLAGRRLQASHTVAFRTLSLL
VIGAYLGLVVIAAELVSLLGGDLGRLAQVGFLVVAAAVTLLWLPSERLRAWVRVTVLKHLFKHRYDYREEWMRFTETIGR
ANDRDLPLFQRAAKAMADIIQSPGAVLFLPDDDGRMIEQSRWNWTGADQSLAALSPDFVTRLAREEFIVEIGHQRPSGDP
RYPQVPAELEADPKAWVIIPLLHFDRNVGVVLLERPNVPRSLDWEDFDLLKIAARQLASYLAEHESQNALMEAAQFDDFN
RRMAFVMHDIKNLASQLQLLSKNAEKHSENPDFRKDMLVTLSSSAGKLNQLLARLGRYGTGQPVVPRPVDLSALARGVVR
RFEADHPVALTRADACSVLADMECLEQAVVHLVQNAIDASDPGMPVSVDVSSDGLHGKIEIVDSGCGMDPEFVRHRLFKP
FVSSKEGGFGIGALEARELVRAMQGRLDVQSRPGIGSRFSITLPLAEAARFLSSNNDQEAA
>Mature_701_residues
MMTGSGLWAFLVMLVHLLSAAGCIVAAAWVIKRPLAKRPDRKPTIAAFALTTIWAIIAASLGAQSDPAVLAETGRNLAWI
LVLYRLFGHDGRDRGMTGIRPVALALAFVSLMQPVLLFVAANWAITPELQEATAQTAAALHMLVAIGALVLLHNLYAGAA
PDTRVTLRWSAAGLTGFWAVELNYFVFAYLVGQAPPEFAAIRGLVAGLMAIPLALGASNGLAGRRLQASHTVAFRTLSLL
VIGAYLGLVVIAAELVSLLGGDLGRLAQVGFLVVAAAVTLLWLPSERLRAWVRVTVLKHLFKHRYDYREEWMRFTETIGR
ANDRDLPLFQRAAKAMADIIQSPGAVLFLPDDDGRMIEQSRWNWTGADQSLAALSPDFVTRLAREEFIVEIGHQRPSGDP
RYPQVPAELEADPKAWVIIPLLHFDRNVGVVLLERPNVPRSLDWEDFDLLKIAARQLASYLAEHESQNALMEAAQFDDFN
RRMAFVMHDIKNLASQLQLLSKNAEKHSENPDFRKDMLVTLSSSAGKLNQLLARLGRYGTGQPVVPRPVDLSALARGVVR
RFEADHPVALTRADACSVLADMECLEQAVVHLVQNAIDASDPGMPVSVDVSSDGLHGKIEIVDSGCGMDPEFVRHRLFKP
FVSSKEGGFGIGALEARELVRAMQGRLDVQSRPGIGSRFSITLPLAEAARFLSSNNDQEAA

Specific function: Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Detects the presence of TMAO in the medium and, in response, activates torR via a four-step phosphorelay. When TMAO is removed,

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=154, Percent_Identity=34.4155844155844, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788549, Length=234, Percent_Identity=24.3589743589744, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788713, Length=159, Percent_Identity=31.4465408805031, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014302
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76469; Mature: 76469

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTGSGLWAFLVMLVHLLSAAGCIVAAAWVIKRPLAKRPDRKPTIAAFALTTIWAIIAAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LGAQSDPAVLAETGRNLAWILVLYRLFGHDGRDRGMTGIRPVALALAFVSLMQPVLLFVA
CCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ANWAITPELQEATAQTAAALHMLVAIGALVLLHNLYAGAAPDTRVTLRWSAAGLTGFWAV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEHH
ELNYFVFAYLVGQAPPEFAAIRGLVAGLMAIPLALGASNGLAGRRLQASHTVAFRTLSLL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHH
VIGAYLGLVVIAAELVSLLGGDLGRLAQVGFLVVAAAVTLLWLPSERLRAWVRVTVLKHL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FKHRYDYREEWMRFTETIGRANDRDLPLFQRAAKAMADIIQSPGAVLFLPDDDGRMIEQS
HHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHC
RWNWTGADQSLAALSPDFVTRLAREEFIVEIGHQRPSGDPRYPQVPAELEADPKAWVIIP
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
LLHFDRNVGVVLLERPNVPRSLDWEDFDLLKIAARQLASYLAEHESQNALMEAAQFDDFN
EEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHH
RRMAFVMHDIKNLASQLQLLSKNAEKHSENPDFRKDMLVTLSSSAGKLNQLLARLGRYGT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEECCCCCHHHHHHHHHCCCCC
GQPVVPRPVDLSALARGVVRRFEADHPVALTRADACSVLADMECLEQAVVHLVQNAIDAS
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPGMPVSVDVSSDGLHGKIEIVDSGCGMDPEFVRHRLFKPFVSSKEGGFGIGALEARELV
CCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
RAMQGRLDVQSRPGIGSRFSITLPLAEAARFLSSNNDQEAA
HHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMTGSGLWAFLVMLVHLLSAAGCIVAAAWVIKRPLAKRPDRKPTIAAFALTTIWAIIAAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LGAQSDPAVLAETGRNLAWILVLYRLFGHDGRDRGMTGIRPVALALAFVSLMQPVLLFVA
CCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ANWAITPELQEATAQTAAALHMLVAIGALVLLHNLYAGAAPDTRVTLRWSAAGLTGFWAV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEHH
ELNYFVFAYLVGQAPPEFAAIRGLVAGLMAIPLALGASNGLAGRRLQASHTVAFRTLSLL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHH
VIGAYLGLVVIAAELVSLLGGDLGRLAQVGFLVVAAAVTLLWLPSERLRAWVRVTVLKHL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FKHRYDYREEWMRFTETIGRANDRDLPLFQRAAKAMADIIQSPGAVLFLPDDDGRMIEQS
HHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHC
RWNWTGADQSLAALSPDFVTRLAREEFIVEIGHQRPSGDPRYPQVPAELEADPKAWVIIP
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
LLHFDRNVGVVLLERPNVPRSLDWEDFDLLKIAARQLASYLAEHESQNALMEAAQFDDFN
EEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHH
RRMAFVMHDIKNLASQLQLLSKNAEKHSENPDFRKDMLVTLSSSAGKLNQLLARLGRYGT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEECCCCCHHHHHHHHHCCCCC
GQPVVPRPVDLSALARGVVRRFEADHPVALTRADACSVLADMECLEQAVVHLVQNAIDAS
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPGMPVSVDVSSDGLHGKIEIVDSGCGMDPEFVRHRLFKPFVSSKEGGFGIGALEARELV
CCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
RAMQGRLDVQSRPGIGSRFSITLPLAEAARFLSSNNDQEAA
HHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]