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The map label for this gene is recG [H]

Identifier: 85373852

GI number: 85373852

Start: 1060371

End: 1062434

Strand: Direct

Name: recG [H]

Synonym: ELI_05125

Alternate gene names: 85373852

Gene position: 1060371-1062434 (Clockwise)

Preceding gene: 85373849

Following gene: 85373854

Centisome position: 34.74

GC content: 65.89

Gene sequence:

>2064_bases
ATGCGCCCCGATATCCTCAATGCCTTGTTTGCCGAGGTCGATACGCTCGATGGCGTGGGGCCGAAGCTCAAGAAGCCGCT
CGACAAGCTGGGGCTGACGCGGGTGCGCGATGTCGCTTATCACCTGCCCGACCGCTTCGTGACGCGGCGGGCAGTGCAGA
ATCTCGATGAGGCGGGCGAGGGCGAGCAGATCGTCATCCAGCTCACGCCGACCGAGCACCGGGGTCCGCGCAATCCGGGC
CGCGGGCCGCACCGTGTCTTCGCGCAAGACGCCATCGGCAATGTGTGCGCGCTGACCTATTTCGGGCGCGCCAGCTATTC
GGCGAAGAAGCTGTTGCCGGTAGGCGAGACGCGCTGGGTCGCCGGCAAGCTGGAACGGTATGGCGACATGCTCCAGATCG
TGCATCCCGACCATGTGCTGGAAGAAGGCGGCGAGAGCCTGCAGCGCCTGTGCGAGCCGGTCTATGCGCTGTCCGAGGGA
CTGACGCAGCCCAAGGTGGCGGGGCTGGTCTCGCAGGCGCTGACGAAGCTGCCCGAGCTTCCCGAATGGATCGAGCCGGG
GCAGTTCGAGAAAGAGCAGTGGCCGATCTGGTCTGATGCGCTCAAGCTGGCGCACAAATCCGAGAATGGTTCGGCGCGCG
ATCGGTTGGCCTATGACGAATTGCTGGCCAATAGCCTTGCGCTGATGCTGGTCCGGGCCGACAATCGCCAGCGCAAGGGC
CGGGCGCTGGTCGGTGACGGCTCGCGTATCGGTAAGCTGCAACTGCCGTTCCCGCTGACCGGCGCGCAGGAGCGCTCGAT
CCGCGAGATCACCGAGGACATGGGGCAGGAAGCGCCAATGCTGCGGCTCCTCCAGGGCGATGTCGGCGCGGGCAAGACGG
TCGTCGCGCTGGAGACGATGCTGGTGGCGGTCGAAGCGGGCGCGCAGGCGGCGCTGCTCGCCCCGACCGAAATCCTCGCG
CGCCAGCATTTCGAGACCCTGCGCGACATGGCGCGGCCAACCGGTACGGAAGTTGCGCTGCTGACCGGGCGCGACAAGGG
CAGGGCGCGTGAAAGCATCCTGATGGGCCTGCTCGACGGATCGATCGATATCGTCGTCGGCACCCACGCAATCTTCCAGG
ACGCGGTGCAATACCGTGACCTCGGCCTCGTAGTGATCGACGAGCAGCATCGCTTCGGCGTCGCCCAGCGGCTGCAACTG
GCGCGCAAGGGCAGACGCACACCGCACACGCTGGCGATGACTGCGACACCGATCCCAAGAACGCTAACACTCGCGCAATA
TGGCGAGATGGATGTCAGCCGCTTGGATGAGCTTCCGCCGGGTAGGCAGGCGATCGACACCCGTGTCGTCGGGCAGGATC
GCCTCGCCGAAGTCGTCGAAGGGGTGGGACGCCATATCGATAAAGGGCAGCAGGCCTATTGGGTCTGCCCGATGGTGCGC
GACAGCGAGACCGTGGATATTGCTGCCGCCGAGGCGCGCTATGCGGCGTTGAAAGAGCGGTTCGGCGACACTGTCGTACT
GGTCCACGGCCAGCTCGAGCCTGCCGCCAAGGACGCAGCTATGGAGCGGTTCGCCAGTGGCGAAGCCAAACTGCTGGTGG
CGACCACCGTGATCGAAGTCGGCGTCGACGTTCCTGCTGCAACCTTGATGGTCATCGAGCAGGCCGAGCGGTTCGGCCTG
GCGCAGTTGCACCAATTGCGCGGCCGCGTGGGACGGGGTTCGGAGAAGTCCGTCTGCCTATTGCTACGCGGCGAAGCGCT
CTCGGACACAGGCCGCAAGCGCCTGGCCCTCATGCGCGAAACGCAGGACGGCTTTCGCATCGCCGAGGAAGACCTCGAAC
TTCGCGGCGGCGGCGAATTGCTTGGCACGCGCCAATCGGGCGACACGCCATTTCGCGTGGCCGACCTTGAGCAAATTCAG
CGCTTACTCCCCGTCGCACACGCCGACGCGCGCCTCCTCATAGAACGCGACGGCGGCCTCAGCTCCGAGCGCGGTGAGGC
CGCGAGAGTGCTGCTTTACCTCTTCGAGCGGGACTACGGCGTACAGCTACTTCGCGGCGGCTAG

Upstream 100 bases:

>100_bases
TGTCATCCCAGGGCAAGCTGGGATCTGTCTCCACAGACACGACGGGATTGTGAGAGATCCGAGCTTTTGCTGGGATGACG
AGAGTGCTTAAAGAACCGCC

Downstream 100 bases:

>100_bases
CTTGGCCACGATGGCTTCAGCAGCCATCCAAACATCGTCCCACGTATATTCGAAATGCTCCTCGCCATCGTAATAGGGAT
CGGCGACCGCAGCACCTTCG

Product: DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 687

Protein sequence:

>687_residues
MRPDILNALFAEVDTLDGVGPKLKKPLDKLGLTRVRDVAYHLPDRFVTRRAVQNLDEAGEGEQIVIQLTPTEHRGPRNPG
RGPHRVFAQDAIGNVCALTYFGRASYSAKKLLPVGETRWVAGKLERYGDMLQIVHPDHVLEEGGESLQRLCEPVYALSEG
LTQPKVAGLVSQALTKLPELPEWIEPGQFEKEQWPIWSDALKLAHKSENGSARDRLAYDELLANSLALMLVRADNRQRKG
RALVGDGSRIGKLQLPFPLTGAQERSIREITEDMGQEAPMLRLLQGDVGAGKTVVALETMLVAVEAGAQAALLAPTEILA
RQHFETLRDMARPTGTEVALLTGRDKGRARESILMGLLDGSIDIVVGTHAIFQDAVQYRDLGLVVIDEQHRFGVAQRLQL
ARKGRRTPHTLAMTATPIPRTLTLAQYGEMDVSRLDELPPGRQAIDTRVVGQDRLAEVVEGVGRHIDKGQQAYWVCPMVR
DSETVDIAAAEARYAALKERFGDTVVLVHGQLEPAAKDAAMERFASGEAKLLVATTVIEVGVDVPAATLMVIEQAERFGL
AQLHQLRGRVGRGSEKSVCLLLRGEALSDTGRKRLALMRETQDGFRIAEEDLELRGGGELLGTRQSGDTPFRVADLEQIQ
RLLPVAHADARLLIERDGGLSSERGEAARVLLYLFERDYGVQLLRGG

Sequences:

>Translated_687_residues
MRPDILNALFAEVDTLDGVGPKLKKPLDKLGLTRVRDVAYHLPDRFVTRRAVQNLDEAGEGEQIVIQLTPTEHRGPRNPG
RGPHRVFAQDAIGNVCALTYFGRASYSAKKLLPVGETRWVAGKLERYGDMLQIVHPDHVLEEGGESLQRLCEPVYALSEG
LTQPKVAGLVSQALTKLPELPEWIEPGQFEKEQWPIWSDALKLAHKSENGSARDRLAYDELLANSLALMLVRADNRQRKG
RALVGDGSRIGKLQLPFPLTGAQERSIREITEDMGQEAPMLRLLQGDVGAGKTVVALETMLVAVEAGAQAALLAPTEILA
RQHFETLRDMARPTGTEVALLTGRDKGRARESILMGLLDGSIDIVVGTHAIFQDAVQYRDLGLVVIDEQHRFGVAQRLQL
ARKGRRTPHTLAMTATPIPRTLTLAQYGEMDVSRLDELPPGRQAIDTRVVGQDRLAEVVEGVGRHIDKGQQAYWVCPMVR
DSETVDIAAAEARYAALKERFGDTVVLVHGQLEPAAKDAAMERFASGEAKLLVATTVIEVGVDVPAATLMVIEQAERFGL
AQLHQLRGRVGRGSEKSVCLLLRGEALSDTGRKRLALMRETQDGFRIAEEDLELRGGGELLGTRQSGDTPFRVADLEQIQ
RLLPVAHADARLLIERDGGLSSERGEAARVLLYLFERDYGVQLLRGG
>Mature_687_residues
MRPDILNALFAEVDTLDGVGPKLKKPLDKLGLTRVRDVAYHLPDRFVTRRAVQNLDEAGEGEQIVIQLTPTEHRGPRNPG
RGPHRVFAQDAIGNVCALTYFGRASYSAKKLLPVGETRWVAGKLERYGDMLQIVHPDHVLEEGGESLQRLCEPVYALSEG
LTQPKVAGLVSQALTKLPELPEWIEPGQFEKEQWPIWSDALKLAHKSENGSARDRLAYDELLANSLALMLVRADNRQRKG
RALVGDGSRIGKLQLPFPLTGAQERSIREITEDMGQEAPMLRLLQGDVGAGKTVVALETMLVAVEAGAQAALLAPTEILA
RQHFETLRDMARPTGTEVALLTGRDKGRARESILMGLLDGSIDIVVGTHAIFQDAVQYRDLGLVVIDEQHRFGVAQRLQL
ARKGRRTPHTLAMTATPIPRTLTLAQYGEMDVSRLDELPPGRQAIDTRVVGQDRLAEVVEGVGRHIDKGQQAYWVCPMVR
DSETVDIAAAEARYAALKERFGDTVVLVHGQLEPAAKDAAMERFASGEAKLLVATTVIEVGVDVPAATLMVIEQAERFGL
AQLHQLRGRVGRGSEKSVCLLLRGEALSDTGRKRLALMRETQDGFRIAEEDLELRGGGELLGTRQSGDTPFRVADLEQIQ
RLLPVAHADARLLIERDGGLSSERGEAARVLLYLFERDYGVQLLRGG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=665, Percent_Identity=41.3533834586466, Blast_Score=433, Evalue=1e-122,
Organism=Escherichia coli, GI1787357, Length=378, Percent_Identity=38.0952380952381, Blast_Score=242, Evalue=5e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 75447; Mature: 75447

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPDILNALFAEVDTLDGVGPKLKKPLDKLGLTRVRDVAYHLPDRFVTRRAVQNLDEAGE
CCCHHHHHHHHHHHHCCCCCHHHHCCHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
GEQIVIQLTPTEHRGPRNPGRGPHRVFAQDAIGNVCALTYFGRASYSAKKLLPVGETRWV
CCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCHHCCCCCCCHHH
AGKLERYGDMLQIVHPDHVLEEGGESLQRLCEPVYALSEGLTQPKVAGLVSQALTKLPEL
HHHHHHHCCCEEEECCHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
PEWIEPGQFEKEQWPIWSDALKLAHKSENGSARDRLAYDELLANSLALMLVRADNRQRKG
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCC
RALVGDGSRIGKLQLPFPLTGAQERSIREITEDMGQEAPMLRLLQGDVGAGKTVVALETM
CEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHH
LVAVEAGAQAALLAPTEILARQHFETLRDMARPTGTEVALLTGRDKGRARESILMGLLDG
HHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCC
SIDIVVGTHAIFQDAVQYRDLGLVVIDEQHRFGVAQRLQLARKGRRTPHTLAMTATPIPR
CEEEEECCHHHHHHHHHHHCCCEEEECCCHHCCHHHHHHHHHHCCCCCCEEEEECCCCCC
TLTLAQYGEMDVSRLDELPPGRQAIDTRVVGQDRLAEVVEGVGRHIDKGQQAYWVCPMVR
EEEHHHHCCCCHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEECCCC
DSETVDIAAAEARYAALKERFGDTVVLVHGQLEPAAKDAAMERFASGEAKLLVATTVIEV
CCCCEEEEHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEEHHHH
GVDVPAATLMVIEQAERFGLAQLHQLRGRVGRGSEKSVCLLLRGEALSDTGRKRLALMRE
CCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHH
TQDGFRIAEEDLELRGGGELLGTRQSGDTPFRVADLEQIQRLLPVAHADARLLIERDGGL
CCCCCEEHHHHHCCCCCCCEEECCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEEECCCC
SSERGEAARVLLYLFERDYGVQLLRGG
CCCCCHHHHHHHHHHHCCCCCEEECCC
>Mature Secondary Structure
MRPDILNALFAEVDTLDGVGPKLKKPLDKLGLTRVRDVAYHLPDRFVTRRAVQNLDEAGE
CCCHHHHHHHHHHHHCCCCCHHHHCCHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
GEQIVIQLTPTEHRGPRNPGRGPHRVFAQDAIGNVCALTYFGRASYSAKKLLPVGETRWV
CCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCHHCCCCCCCHHH
AGKLERYGDMLQIVHPDHVLEEGGESLQRLCEPVYALSEGLTQPKVAGLVSQALTKLPEL
HHHHHHHCCCEEEECCHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
PEWIEPGQFEKEQWPIWSDALKLAHKSENGSARDRLAYDELLANSLALMLVRADNRQRKG
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCC
RALVGDGSRIGKLQLPFPLTGAQERSIREITEDMGQEAPMLRLLQGDVGAGKTVVALETM
CEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHH
LVAVEAGAQAALLAPTEILARQHFETLRDMARPTGTEVALLTGRDKGRARESILMGLLDG
HHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCC
SIDIVVGTHAIFQDAVQYRDLGLVVIDEQHRFGVAQRLQLARKGRRTPHTLAMTATPIPR
CEEEEECCHHHHHHHHHHHCCCEEEECCCHHCCHHHHHHHHHHCCCCCCEEEEECCCCCC
TLTLAQYGEMDVSRLDELPPGRQAIDTRVVGQDRLAEVVEGVGRHIDKGQQAYWVCPMVR
EEEHHHHCCCCHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEECCCC
DSETVDIAAAEARYAALKERFGDTVVLVHGQLEPAAKDAAMERFASGEAKLLVATTVIEV
CCCCEEEEHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEEHHHH
GVDVPAATLMVIEQAERFGLAQLHQLRGRVGRGSEKSVCLLLRGEALSDTGRKRLALMRE
CCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHH
TQDGFRIAEEDLELRGGGELLGTRQSGDTPFRVADLEQIQRLLPVAHADARLLIERDGGL
CCCCCEEHHHHHCCCCCCCEEECCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEEECCCC
SSERGEAARVLLYLFERDYGVQLLRGG
CCCCCHHHHHHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]