Click here to switch to the map view.

The map label for this gene is 85373799

Identifier: 85373799

GI number: 85373799

Start: 1001895

End: 1002935

Strand: Reverse

Name: 85373799

Synonym: ELI_04860

Alternate gene names: NA

Gene position: 1002935-1001895 (Counterclockwise)

Preceding gene: 85373800

Following gene: 85373796

Centisome position: 32.86

GC content: 62.34

Gene sequence:

>1041_bases
ATGGCCGTGGGACTAGCCGAACATGACAAGGAAGCCTGGGGCAGGCTGCCTTTTTCGCTGACAATCGCAGACATTTCGCA
AGACGACGAGCCGCTCATCTATGTGAACCGCGCGTTCGAGCAGATGACCGGCTATTCGCGATCTTCCGTGGTCGGTCGCA
ACTGCCGCTTCCTGCAAGGCGAAAAGACTGATCCGGGTGCGGTCGAGCGTCTCGCTAAAGCGATCAGGAATTGCGAAGAG
GTCGAAGAGACGATCTACAACTATCGCGCCGATGGCGAAGGCTTCTGGAACCATCTCCTGATGGGGCCTCTCGAAGACCA
GGACGAGAAATGCCGCTATTTCGTCGGCATCCAGGTTGACATGGGCCAAAGCGAGAGCCCCGACCGCGCGACCGAGCTGG
ATCGGCAGCTCGCGGAGGTCCAGCACCGGGTGAAGAACCACCTGGCAATGATCGTGAGCATGATCCGCATCCAGTCCAGC
CAGGCGGGCGGTGTCGGTTCGCAATTCGACAGCCTCTCGCGCCGGGTGGAAGCGTTGCAATTGCTCTACCAGGAAATGGA
CATCGCGGGCGCGGCGAAGGCGACCGACAAGATCATCCCTCTCGGCGCCTATCTCGGGCGCATCGCATCCGCCATCAACC
ACATCGACGGTCGCGGGGCGATCAAGGTCAATGTCCAGGCCGACACGGTCGATGTGCCGGTCGAGACCGCCGGCAGGATC
GGCCTGCTGGTGTCGGAAGTCCTCACCAACGCGCTGCAACACGCCTTCAGCGACCGTGCGAGCGGAGTCGTCCAGCTCCG
TTCGTCGGTCATGTCCGGCGAGCAGCTCCGCGTCACGGTGGAGGACGACGGCCGGGGAATTCCCGAGGATTGCGACTGGC
CCAACGAAGGCAATCTCGGTTCGCGCATCGTCCGGCAGCTCGTGCAGGGACTGGGCGCCGAACTCAACGTCACCCGCGGG
GGCACCGGGACCATCGTCAACATCGACATCCCGCTGTCGCAACAAAAGACCCTGATCGCCGACGAGCGGACCAAAGATTA
G

Upstream 100 bases:

>100_bases
TGGCACTCGAATTTGCGAACCGGCCCCGATTTTGATAACAATCCAAATGCCTTGCGGTTGATAGTTGCGGTGGGCGCATC
TCCGGCAAGACGATTTGGGG

Downstream 100 bases:

>100_bases
GTCGCGCCTTTGCCGAAGGGTTTGTCGAGCCGGACGATTTTCCGGTCGAGGATGGCCGCGAAGCCGACCCAAGGCAAAAC
AGGGAACGAGTTACTCAAAC

Product: sensory box histidine kinase

Products: NA

Alternate protein names: EL346-LOV-histidine kinase; EL346-LOV-HK

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MAVGLAEHDKEAWGRLPFSLTIADISQDDEPLIYVNRAFEQMTGYSRSSVVGRNCRFLQGEKTDPGAVERLAKAIRNCEE
VEETIYNYRADGEGFWNHLLMGPLEDQDEKCRYFVGIQVDMGQSESPDRATELDRQLAEVQHRVKNHLAMIVSMIRIQSS
QAGGVGSQFDSLSRRVEALQLLYQEMDIAGAAKATDKIIPLGAYLGRIASAINHIDGRGAIKVNVQADTVDVPVETAGRI
GLLVSEVLTNALQHAFSDRASGVVQLRSSVMSGEQLRVTVEDDGRGIPEDCDWPNEGNLGSRIVRQLVQGLGAELNVTRG
GTGTIVNIDIPLSQQKTLIADERTKD

Sequences:

>Translated_346_residues
MAVGLAEHDKEAWGRLPFSLTIADISQDDEPLIYVNRAFEQMTGYSRSSVVGRNCRFLQGEKTDPGAVERLAKAIRNCEE
VEETIYNYRADGEGFWNHLLMGPLEDQDEKCRYFVGIQVDMGQSESPDRATELDRQLAEVQHRVKNHLAMIVSMIRIQSS
QAGGVGSQFDSLSRRVEALQLLYQEMDIAGAAKATDKIIPLGAYLGRIASAINHIDGRGAIKVNVQADTVDVPVETAGRI
GLLVSEVLTNALQHAFSDRASGVVQLRSSVMSGEQLRVTVEDDGRGIPEDCDWPNEGNLGSRIVRQLVQGLGAELNVTRG
GTGTIVNIDIPLSQQKTLIADERTKD
>Mature_345_residues
AVGLAEHDKEAWGRLPFSLTIADISQDDEPLIYVNRAFEQMTGYSRSSVVGRNCRFLQGEKTDPGAVERLAKAIRNCEEV
EETIYNYRADGEGFWNHLLMGPLEDQDEKCRYFVGIQVDMGQSESPDRATELDRQLAEVQHRVKNHLAMIVSMIRIQSSQ
AGGVGSQFDSLSRRVEALQLLYQEMDIAGAAKATDKIIPLGAYLGRIASAINHIDGRGAIKVNVQADTVDVPVETAGRIG
LLVSEVLTNALQHAFSDRASGVVQLRSSVMSGEQLRVTVEDDGRGIPEDCDWPNEGNLGSRIVRQLVQGLGAELNVTRGG
TGTIVNIDIPLSQQKTLIADERTKD

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LVHK2_ERYLH (Q2NB77)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_457861.1
- STRING:   Q2NB77
- GeneID:   3869050
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_04860
- NMPDR:   fig|314225.3.peg.2100
- eggNOG:   COG3920
- HOGENOM:   HBG465978
- OMA:   MISAMLT
- ProtClustDB:   CLSK944463
- BioCyc:   ELIT314225:ELI_04860-MONOMER
- GO:   GO:0009405
- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR011495
- InterPro:   IPR005467
- Gene3D:   G3DSA:3.30.565.10
- PRINTS:   PR00344
- SMART:   SM00387
- SMART:   SM00086
- SMART:   SM00091
- TIGRFAMs:   TIGR00229

Pfam domain/function: PF02518 HATPase_c; PF07568 HisKA_2; PF00989 PAS; SSF55874 ATP_bd_ATPase

EC number: =2.7.13.3

Molecular weight: Translated: 37948; Mature: 37817

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50109 HIS_KIN; PS50113 PAC; PS50112 PAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVGLAEHDKEAWGRLPFSLTIADISQDDEPLIYVNRAFEQMTGYSRSSVVGRNCRFLQG
CCCCCCCCCHHHHCCCCEEEEEEECCCCCCCEEEHHHHHHHHHCCCHHHHCCCCCEEECC
EKTDPGAVERLAKAIRNCEEVEETIYNYRADGEGFWNHLLMGPLEDQDEKCRYFVGIQVD
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEEEE
MGQSESPDRATELDRQLAEVQHRVKNHLAMIVSMIRIQSSQAGGVGSQFDSLSRRVEALQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LLYQEMDIAGAAKATDKIIPLGAYLGRIASAINHIDGRGAIKVNVQADTVDVPVETAGRI
HHHHHHHHCCCCHHHCCEEEHHHHHHHHHHHHHCCCCCCEEEEEEEECEEECCHHCCCHH
GLLVSEVLTNALQHAFSDRASGVVQLRSSVMSGEQLRVTVEDDGRGIPEDCDWPNEGNLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCHH
SRIVRQLVQGLGAELNVTRGGTGTIVNIDIPLSQQKTLIADERTKD
HHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCEECCCCCCC
>Mature Secondary Structure 
AVGLAEHDKEAWGRLPFSLTIADISQDDEPLIYVNRAFEQMTGYSRSSVVGRNCRFLQG
CCCCCCCCHHHHCCCCEEEEEEECCCCCCCEEEHHHHHHHHHCCCHHHHCCCCCEEECC
EKTDPGAVERLAKAIRNCEEVEETIYNYRADGEGFWNHLLMGPLEDQDEKCRYFVGIQVD
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEEEE
MGQSESPDRATELDRQLAEVQHRVKNHLAMIVSMIRIQSSQAGGVGSQFDSLSRRVEALQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LLYQEMDIAGAAKATDKIIPLGAYLGRIASAINHIDGRGAIKVNVQADTVDVPVETAGRI
HHHHHHHHCCCCHHHCCEEEHHHHHHHHHHHHHCCCCCCEEEEEEEECEEECCHHCCCHH
GLLVSEVLTNALQHAFSDRASGVVQLRSSVMSGEQLRVTVEDDGRGIPEDCDWPNEGNLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCHH
SRIVRQLVQGLGAELNVTRGGTGTIVNIDIPLSQQKTLIADERTKD
HHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA