Click here to switch to the map view.

The map label for this gene is cnrH [H]

Identifier: 85373748

GI number: 85373748

Start: 952478

End: 953035

Strand: Direct

Name: cnrH [H]

Synonym: ELI_04605

Alternate gene names: 85373748

Gene position: 952478-953035 (Clockwise)

Preceding gene: 85373747

Following gene: 85373749

Centisome position: 31.2

GC content: 62.9

Gene sequence:

>558_bases
GTGGATGACACTTCGAATGAAGCTCTGATCGGGCGGGCGATAGCCGGTGACAAGCGGGCGTTCACAGCTCTCGTCGAGAG
CGAGATCGCCCGGTTGATTGCGCTTGCCACGCGCATGCTGGGTTCACCATCGCGGGCCGAAGATGTCGTTCAGGACGGTC
TCGCGTCGGTCTGGCTGACTCGTCATCGCCTCGATCCGAGCAAGCCCATCGGTCCCTATTTGACGACAATCGTTCTCAAC
CGGTGCCGCGACAGGCTCCGCCGCAGGAAAGTTATTGGCTTCCTTGGTTTGCCGGATGGGCGGGAAGCCGACGCCGTTGC
CGACGATGCTCCTAATCCCGAAAATGTTGCCGGAGCCCGCGAACAGCTGCGGCTGGTCCAGGCCGAAATCGGGCGCTTGC
CGGTGCGCCTACAAGAGGCGCTCGTGCTGGTCACTGTCGAGGGGTACAGCCAGGCCGAGGCTGCCGAGCTGCTCGGCACC
ACCGAGAAAGCCGTCGAGACGCGCATCTATCGTGCGCGCAACCGGCTGAAGGAGCGGTTCGAAAAGTTTGAGGGGTAG

Upstream 100 bases:

>100_bases
CATGCGGGAAATTCTCGATCCCGATCAGCAGCTCCAGTTCGACCGGAAAGTGTCCGCGGCCCTCACGCGCGATCCGCGTG
ACTGACCAGCCTTGGCAGCG

Downstream 100 bases:

>100_bases
GGCAGGTGGCCGCGTATGTGACGGTATACGCATTTTCAGGAGCCCCCTATGCCTGCCCTCAATCGCCGAAAATTCCTTGG
AACAAGTGCTAGCGGGCTGG

Product: RNA polymerase ECF-type sigma factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MDDTSNEALIGRAIAGDKRAFTALVESEIARLIALATRMLGSPSRAEDVVQDGLASVWLTRHRLDPSKPIGPYLTTIVLN
RCRDRLRRRKVIGFLGLPDGREADAVADDAPNPENVAGAREQLRLVQAEIGRLPVRLQEALVLVTVEGYSQAEAAELLGT
TEKAVETRIYRARNRLKERFEKFEG

Sequences:

>Translated_185_residues
MDDTSNEALIGRAIAGDKRAFTALVESEIARLIALATRMLGSPSRAEDVVQDGLASVWLTRHRLDPSKPIGPYLTTIVLN
RCRDRLRRRKVIGFLGLPDGREADAVADDAPNPENVAGAREQLRLVQAEIGRLPVRLQEALVLVTVEGYSQAEAAELLGT
TEKAVETRIYRARNRLKERFEKFEG
>Mature_185_residues
MDDTSNEALIGRAIAGDKRAFTALVESEIARLIALATRMLGSPSRAEDVVQDGLASVWLTRHRLDPSKPIGPYLTTIVLN
RCRDRLRRRKVIGFLGLPDGREADAVADDAPNPENVAGAREQLRLVQAEIGRLPVRLQEALVLVTVEGYSQAEAAELLGT
TEKAVETRIYRARNRLKERFEKFEG

Specific function: CnrH alone is able to activate CNR expression, while both CnrY and CrnX are needed for nickel induction of cnrH (PubMed:10671463). Binds DNA in a RNA polymerase-dependent fashion (PubMed:10671464). CnrH may be controlled by a CnrYX transmembrane anti-sigm

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20489; Mature: 20489

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDTSNEALIGRAIAGDKRAFTALVESEIARLIALATRMLGSPSRAEDVVQDGLASVWLT
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
RHRLDPSKPIGPYLTTIVLNRCRDRLRRRKVIGFLGLPDGREADAVADDAPNPENVAGAR
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
EQLRLVQAEIGRLPVRLQEALVLVTVEGYSQAEAAELLGTTEKAVETRIYRARNRLKERF
HHHHHHHHHHCCCCHHHHHEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
EKFEG
HHHCC
>Mature Secondary Structure
MDDTSNEALIGRAIAGDKRAFTALVESEIARLIALATRMLGSPSRAEDVVQDGLASVWLT
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
RHRLDPSKPIGPYLTTIVLNRCRDRLRRRKVIGFLGLPDGREADAVADDAPNPENVAGAR
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
EQLRLVQAEIGRLPVRLQEALVLVTVEGYSQAEAAELLGTTEKAVETRIYRARNRLKERF
HHHHHHHHHHCCCCHHHHHEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
EKFEG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8380802; 8052622; 10671463; 10671464 [H]