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The map label for this gene is czcC [H]

Identifier: 85373716

GI number: 85373716

Start: 920057

End: 921310

Strand: Reverse

Name: czcC [H]

Synonym: ELI_04445

Alternate gene names: 85373716

Gene position: 921310-920057 (Counterclockwise)

Preceding gene: 85373718

Following gene: 85373715

Centisome position: 30.18

GC content: 64.19

Gene sequence:

>1254_bases
ATGTTTGCCATTATTTGGCGAGGCGCCCTTTTTGCAGGGCTGAGCCTCGCAGTACTGCCCGGTGCGGTGCGTGCACAAGA
ACGCGCGGTGTTGACGCTCGACGAAGCTCTCGCGCGTGCGGGTGTGGACGAAAGCGCGCAGGTGCAATCAGACAATCCGC
GTTTGATCGGGCCGCAGGCCGAAACGGACGCGGCACGCGCGCTTATCGATCAGGCACGGCTTCGGCCAAATCCTGAGCTT
GCCTTTGAAGCGGAGAACATCGCAGGAAGCGGTGCCTTTTCAGGGCTGCAAGCAACCGAATATACGCTGTCTTTGAGTCA
GCGCCTCGAGCTAGGCGGCAAGCGGGGCGCACGCATTCGCTCGGCCGAGGCCGAGGCGCGCGTGGCAATGCTTTCTGGAG
AATTGTCGGTCGCTGAGCTGAGTCGCATGGTGCGCGAACGCTACATCGAGGCGGTCGCTTCAGCTGCGCGACTGGAACTT
GCCCGCGACGTAGTCGAACGCAATCGCGAACTCGCGCGTATAGCTGGCCTGCTTGTCGAAGTTGGCCGCGAGCCGCCGCT
GCGCTCGCTTCGTGCAGAAGCGGCCCTTGCTGAAGCCGAGGCGGAGTTTGAAGCCGCGCGAGCTTCAGAGATAGCGGCGC
GGAGCGCGTTGGTGGCGCTCTGGGGTGAAACGTCCCCTCCCCCGGACGTGCCATCGGCGTTTCCCGGGATCGAACCTCCT
GCGATGCTTCTTGCATCGCCTTCTGCTTTGCGTCTCCAAGTCGCGCGTGCCGAACGCGAGGCGGCGGACGCTGCGATCGA
CAGGGAGCGCTCTTTGGGTGTTCCCGATCCGGCCATCTCCGCCGGTGTCAGGCGGTTCGAGGAAAGCAGGGATCAGGCCT
TCCTAGTGGGCGTCTCGATTCCCCTTCCTTTCCGCAATCGCAATCAGGGTAACATCGCCGCTGCCGAGGCCCGCTTCCGC
GCGGCCTCCGCACGCGAGGCTGTCGCCCGCGCGGATTTCGAACTCGAAGTAACCCAGGCGCGCGGCCGCTTTCTCGCCGC
CGAGGCTCGTGTAGAGACTCTGTCCCAAACCTCCCTGCCTCAAGCGGAAGAAGCCTTGCGCCTCGTCCGGATTGGGTATC
GCAACGGCAGGTTCCCGCTGATCGAGGTTCTGGCTGCGGCCGAAGCCCGCGATGCAATCCGAGAAGCCTTGATCCAAGCC
CAGGAAGATCGCGGTCGCCTGGCGGCGCAGTTGATCTGGCTTGGCGCCCAATGA

Upstream 100 bases:

>100_bases
CAGCAAGCGATTTTGACGCCCCCTCCTCGAATCTGACGTCCAGTATTGCCGCCGCAATGTCGGCGCGCATTCGGCATGTC
AGTAGAGGAAAAATCAATTC

Downstream 100 bases:

>100_bases
GGAAAATACCCATGAACCGTAAGCGTTTGGCCGTACTGATCGGCCTGATCATTCTTGTTTTTGCGGCTGCTGTAATGCTG
TGGCCGGACAACGGCGCAGA

Product: metal ion efflux outer membrane factor protein family protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MFAIIWRGALFAGLSLAVLPGAVRAQERAVLTLDEALARAGVDESAQVQSDNPRLIGPQAETDAARALIDQARLRPNPEL
AFEAENIAGSGAFSGLQATEYTLSLSQRLELGGKRGARIRSAEAEARVAMLSGELSVAELSRMVRERYIEAVASAARLEL
ARDVVERNRELARIAGLLVEVGREPPLRSLRAEAALAEAEAEFEAARASEIAARSALVALWGETSPPPDVPSAFPGIEPP
AMLLASPSALRLQVARAEREAADAAIDRERSLGVPDPAISAGVRRFEESRDQAFLVGVSIPLPFRNRNQGNIAAAEARFR
AASAREAVARADFELEVTQARGRFLAAEARVETLSQTSLPQAEEALRLVRIGYRNGRFPLIEVLAAAEARDAIREALIQA
QEDRGRLAAQLIWLGAQ

Sequences:

>Translated_417_residues
MFAIIWRGALFAGLSLAVLPGAVRAQERAVLTLDEALARAGVDESAQVQSDNPRLIGPQAETDAARALIDQARLRPNPEL
AFEAENIAGSGAFSGLQATEYTLSLSQRLELGGKRGARIRSAEAEARVAMLSGELSVAELSRMVRERYIEAVASAARLEL
ARDVVERNRELARIAGLLVEVGREPPLRSLRAEAALAEAEAEFEAARASEIAARSALVALWGETSPPPDVPSAFPGIEPP
AMLLASPSALRLQVARAEREAADAAIDRERSLGVPDPAISAGVRRFEESRDQAFLVGVSIPLPFRNRNQGNIAAAEARFR
AASAREAVARADFELEVTQARGRFLAAEARVETLSQTSLPQAEEALRLVRIGYRNGRFPLIEVLAAAEARDAIREALIQA
QEDRGRLAAQLIWLGAQ
>Mature_417_residues
MFAIIWRGALFAGLSLAVLPGAVRAQERAVLTLDEALARAGVDESAQVQSDNPRLIGPQAETDAARALIDQARLRPNPEL
AFEAENIAGSGAFSGLQATEYTLSLSQRLELGGKRGARIRSAEAEARVAMLSGELSVAELSRMVRERYIEAVASAARLEL
ARDVVERNRELARIAGLLVEVGREPPLRSLRAEAALAEAEAEFEAARASEIAARSALVALWGETSPPPDVPSAFPGIEPP
AMLLASPSALRLQVARAEREAADAAIDRERSLGVPDPAISAGVRRFEESRDQAFLVGVSIPLPFRNRNQGNIAAAEARFR
AASAREAVARADFELEVTQARGRFLAAEARVETLSQTSLPQAEEALRLVRIGYRNGRFPLIEVLAAAEARDAIREALIQA
QEDRGRLAAQLIWLGAQ

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 44822; Mature: 44822

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAIIWRGALFAGLSLAVLPGAVRAQERAVLTLDEALARAGVDESAQVQSDNPRLIGPQA
CEEEEECHHHHHCCHHHHCCCHHHHHCCCEEHHHHHHHHCCCCCCCCCCCCCCEEECCCC
ETDAARALIDQARLRPNPELAFEAENIAGSGAFSGLQATEYTLSLSQRLELGGKRGARIR
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEE
SAEAEARVAMLSGELSVAELSRMVRERYIEAVASAARLELARDVVERNRELARIAGLLVE
CCHHHHEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGREPPLRSLRAEAALAEAEAEFEAARASEIAARSALVALWGETSPPPDVPSAFPGIEPP
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCC
AMLLASPSALRLQVARAEREAADAAIDRERSLGVPDPAISAGVRRFEESRDQAFLVGVSI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEE
PLPFRNRNQGNIAAAEARFRAASAREAVARADFELEVTQARGRFLAAEARVETLSQTSLP
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEEEHHCCCEEEHHHHHHHHHHCCCC
QAEEALRLVRIGYRNGRFPLIEVLAAAEARDAIREALIQAQEDRGRLAAQLIWLGAQ
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHEEECCC
>Mature Secondary Structure
MFAIIWRGALFAGLSLAVLPGAVRAQERAVLTLDEALARAGVDESAQVQSDNPRLIGPQA
CEEEEECHHHHHCCHHHHCCCHHHHHCCCEEHHHHHHHHCCCCCCCCCCCCCCEEECCCC
ETDAARALIDQARLRPNPELAFEAENIAGSGAFSGLQATEYTLSLSQRLELGGKRGARIR
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEE
SAEAEARVAMLSGELSVAELSRMVRERYIEAVASAARLELARDVVERNRELARIAGLLVE
CCHHHHEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGREPPLRSLRAEAALAEAEAEFEAARASEIAARSALVALWGETSPPPDVPSAFPGIEPP
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCC
AMLLASPSALRLQVARAEREAADAAIDRERSLGVPDPAISAGVRRFEESRDQAFLVGVSI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEE
PLPFRNRNQGNIAAAEARFRAASAREAVARADFELEVTQARGRFLAAEARVETLSQTSLP
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEEEHHCCCEEEHHHHHHHHHHCCCC
QAEEALRLVRIGYRNGRFPLIEVLAAAEARDAIREALIQAQEDRGRLAAQLIWLGAQ
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]