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The map label for this gene is ahpC [C]

Identifier: 85373707

GI number: 85373707

Start: 906816

End: 907472

Strand: Reverse

Name: ahpC [C]

Synonym: ELI_04400

Alternate gene names: 85373707

Gene position: 907472-906816 (Counterclockwise)

Preceding gene: 85373708

Following gene: 85373704

Centisome position: 29.73

GC content: 55.4

Gene sequence:

>657_bases
ATGACCCTCTCCATTGGCTCGACAGCTCCCGATTTCACAGCGGAAACGACCCAAGGCACCATCACCTTCCATGATTGGAT
GGGCGACAATTGGGCTATCCTGTTTTCTCATCCAAAGGCATTTACCCCGGTTTGTACGACCGAGCTGGGTTACATGGCCG
GTCTCGGCGAGGAATTTGCCAAACGCGACACCAAGATTCTCGGCCTGTCGGTCGACAGCAGCCAAGACAATCGCGACTGG
CTACCCGATATCGAGGCGGTCAGCGGCAATAAAGTCGATTACCCGGTGGTCGGCGACAGCGACCTGAAGGTGGCCAAACT
CTACAATATGTTGCCCGCCGAGGAGACTGGCAGTGCGGAGCAAAGAACCGCAGCCGACAATGCTACCGTTCGCGCCGTCT
ATATCGTTGGCCCGGACAAAAAAATCCGTGCGATGCTACTCTATCCGATGAGCAGCGGACGCAATTTCGAAGAAGTGCTC
CGATTGCTCGATTCAGTCCAGCTCACCGAAAGTAAAGGCGTGGCAACCCCGGTCAATTGGCAGAGTGGGGATGACGTCAT
CATTCCACCGTCTGTTTCCGATAAAGAAGCGAAAGCGCGCTTCCCGCAAGGTTTCACAACGCTGCGCCCCTATCTGCGCA
CGGTTAAAATCGACTGA

Upstream 100 bases:

>100_bases
ACGCAATCGATTGCGCCGACATTCGACGTGCCGCAGGCCACACACCCGCCAAAATATGAGGACGGCGGACACCTCCCCCA
GAATAAATAGGAGTTTTGAC

Downstream 100 bases:

>100_bases
CCAGCGCAAGCGGATGTGGTGTATTTGGGCTCGAACTCAACAGGGGAACCCGCATGAAGCTAGACAAAAGCAGTCACGCA
ACTGCGGCTTCTGCCGCATT

Product: peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTLSIGSTAPDFTAETTQGTITFHDWMGDNWAILFSHPKAFTPVCTTELGYMAGLGEEFAKRDTKILGLSVDSSQDNRDW
LPDIEAVSGNKVDYPVVGDSDLKVAKLYNMLPAEETGSAEQRTAADNATVRAVYIVGPDKKIRAMLLYPMSSGRNFEEVL
RLLDSVQLTESKGVATPVNWQSGDDVIIPPSVSDKEAKARFPQGFTTLRPYLRTVKID

Sequences:

>Translated_218_residues
MTLSIGSTAPDFTAETTQGTITFHDWMGDNWAILFSHPKAFTPVCTTELGYMAGLGEEFAKRDTKILGLSVDSSQDNRDW
LPDIEAVSGNKVDYPVVGDSDLKVAKLYNMLPAEETGSAEQRTAADNATVRAVYIVGPDKKIRAMLLYPMSSGRNFEEVL
RLLDSVQLTESKGVATPVNWQSGDDVIIPPSVSDKEAKARFPQGFTTLRPYLRTVKID
>Mature_217_residues
TLSIGSTAPDFTAETTQGTITFHDWMGDNWAILFSHPKAFTPVCTTELGYMAGLGEEFAKRDTKILGLSVDSSQDNRDWL
PDIEAVSGNKVDYPVVGDSDLKVAKLYNMLPAEETGSAEQRTAADNATVRAVYIVGPDKKIRAMLLYPMSSGRNFEEVLR
LLDSVQLTESKGVATPVNWQSGDDVIIPPSVSDKEAKARFPQGFTTLRPYLRTVKID

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=220, Percent_Identity=46.8181818181818, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI4505591, Length=198, Percent_Identity=28.2828282828283, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI32455266, Length=198, Percent_Identity=28.2828282828283, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI32455264, Length=198, Percent_Identity=28.2828282828283, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI32189392, Length=198, Percent_Identity=28.2828282828283, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI5453549, Length=166, Percent_Identity=27.710843373494, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI5802974, Length=177, Percent_Identity=25.9887005649718, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI32483377, Length=177, Percent_Identity=25.9887005649718, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786822, Length=160, Percent_Identity=26.875, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25153706, Length=235, Percent_Identity=39.1489361702128, Blast_Score=169, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI32565831, Length=190, Percent_Identity=27.8947368421053, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193204376, Length=190, Percent_Identity=27.8947368421053, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17554494, Length=204, Percent_Identity=24.0196078431373, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319407, Length=215, Percent_Identity=49.3023255813954, Blast_Score=217, Evalue=9e-58,
Organism=Saccharomyces cerevisiae, GI6323613, Length=168, Percent_Identity=29.1666666666667, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6320661, Length=178, Percent_Identity=28.6516853932584, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24652436, Length=208, Percent_Identity=46.6346153846154, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24652434, Length=208, Percent_Identity=46.1538461538462, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI17975518, Length=208, Percent_Identity=46.1538461538462, Blast_Score=191, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24581278, Length=217, Percent_Identity=43.3179723502304, Blast_Score=191, Evalue=3e-49,
Organism=Drosophila melanogaster, GI17157991, Length=177, Percent_Identity=29.3785310734463, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641739, Length=177, Percent_Identity=29.3785310734463, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357347, Length=186, Percent_Identity=30.6451612903226, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17738015, Length=206, Percent_Identity=27.1844660194175, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24656348, Length=171, Percent_Identity=28.0701754385965, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17864676, Length=171, Percent_Identity=28.0701754385965, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23938; Mature: 23807

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSIGSTAPDFTAETTQGTITFHDWMGDNWAILFSHPKAFTPVCTTELGYMAGLGEEFA
CEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHH
KRDTKILGLSVDSSQDNRDWLPDIEAVSGNKVDYPVVGDSDLKVAKLYNMLPAEETGSAE
HCCCEEEEEEECCCCCCCCCCCCCEECCCCCCCCCEECCCCCHHHHHHHCCCCCCCCCCH
QRTAADNATVRAVYIVGPDKKIRAMLLYPMSSGRNFEEVLRLLDSVQLTESKGVATPVNW
HHHCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHEECCCCCCCCCCCC
QSGDDVIIPPSVSDKEAKARFPQGFTTLRPYLRTVKID
CCCCCEEECCCCCCCHHHHCCCCCHHHHHHHHEEEECC
>Mature Secondary Structure 
TLSIGSTAPDFTAETTQGTITFHDWMGDNWAILFSHPKAFTPVCTTELGYMAGLGEEFA
EEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHH
KRDTKILGLSVDSSQDNRDWLPDIEAVSGNKVDYPVVGDSDLKVAKLYNMLPAEETGSAE
HCCCEEEEEEECCCCCCCCCCCCCEECCCCCCCCCEECCCCCHHHHHHHCCCCCCCCCCH
QRTAADNATVRAVYIVGPDKKIRAMLLYPMSSGRNFEEVLRLLDSVQLTESKGVATPVNW
HHHCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHEECCCCCCCCCCCC
QSGDDVIIPPSVSDKEAKARFPQGFTTLRPYLRTVKID
CCCCCEEECCCCCCCHHHHCCCCCHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]