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The map label for this gene is yrbE [H]

Identifier: 85373570

GI number: 85373570

Start: 769346

End: 770431

Strand: Direct

Name: yrbE [H]

Synonym: ELI_03715

Alternate gene names: 85373570

Gene position: 769346-770431 (Clockwise)

Preceding gene: 85373566

Following gene: 85373571

Centisome position: 25.2

GC content: 63.35

Gene sequence:

>1086_bases
GTGAGCACGCACAAGACCTATGCGATTATCGGCTGCGGCATGATGGGCCGCGAGCATATGCGTAATATCGCGCTGGTCGA
TGATGCGGAGCTGGTGGCGATTGCCGATCCCGATGCCGGATCGCGCGACCTGGCGGCCAAACAGGCGGCAGAGCTGGGCC
AATCGCCGGTTATCCTCGCCACGACCGACGAGCTGTTCGCGGCCACTTCGCCCGATGCGGTCATCGTCGCGTCGCCCAAT
TTCACGCATTTCGACGTGGTGCAGCCGATCATGGAGCGGGGCTGCGCGATCCTGCTGGAAAAGCCCATGTGTACGACCGT
GGAGGATGCGCGCGCATTGGAGCGGCTGGTGGAGCAATACGAACCGCTGTTCTGGGTCGGGCTGGAATATCGCTACATGC
CGCCGGTGACACGCTTCATCGAGCGGGTGCAGGCGGGCGAGGCGGGCCCGGTCAAGATGCTGACCATTCGCGAGCATCGC
TTTCCCTTCCTTCCCAAGGTCGGCGACTGGAACCGGTTCAACTGCAACACGGGCGGGACGCTGGTCGAGAAGTGCTGCCA
TTTTTTCGACCTGATGCGGCATATACTGCAGGACGAGCCGGTGCGGATCTTCGCCAGCGGCGCGCAGGATGTGAACCATC
TCGACGAGAGCTATGCGGGCGAGACGCCCGACATCATCGACAACGCCTATGTGCTGGTCGATTTCGCGGGCGGCGCGCGG
GCGGTGCTCGATCTGTGTATGTTCGCGGAAGGCTCCCAAGAACAGGAAGACATCTATGTCGCCGGACCTGTCGGCAAGCT
CGAAGTGCAATTGCCCGGCGGCAAGGTGATCTGGTCCCCGCGTGACCGAAGCGGGCCCTTCGTTGAGCAGGTCGATGTCA
CGCCCGAAGCGTTGGCGGCGGGCGACCATCACGGTGCGACCTATTACCAACTGCTCAAATTCCATGCCGCTTTGGCGGGG
AGCACCGCGCCCCGGATCACCGCAACCGACGGTGTGCGCTCGGTAGAGATGGGGGCAGCGGCACAGCAAAGCATCGCGAC
GGGCCAGCCTGTCGCACTCGATTTCTCGAAGGGAGCAGCAGCGTGA

Upstream 100 bases:

>100_bases
TTCATCGCGGGCACCCTCTCCAGTTCGCTCGCGATGGCAGCAAGCGCAGAGGCTCGCAAGAGCGCTTGTCTTTTCGCCGT
GCCACCCCCACAGGCGGGGC

Downstream 100 bases:

>100_bases
TCGAGACGATACCGCAAGTGGGGTTCGGCCTCTGGAAAGTGCCGGGCGAAGATTGCGAAAGGGTCGTGCTCGAGGCTATC
CGCGCGGGCTATCGCCATTT

Product: myo-inositol-2-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSTHKTYAIIGCGMMGREHMRNIALVDDAELVAIADPDAGSRDLAAKQAAELGQSPVILATTDELFAATSPDAVIVASPN
FTHFDVVQPIMERGCAILLEKPMCTTVEDARALERLVEQYEPLFWVGLEYRYMPPVTRFIERVQAGEAGPVKMLTIREHR
FPFLPKVGDWNRFNCNTGGTLVEKCCHFFDLMRHILQDEPVRIFASGAQDVNHLDESYAGETPDIIDNAYVLVDFAGGAR
AVLDLCMFAEGSQEQEDIYVAGPVGKLEVQLPGGKVIWSPRDRSGPFVEQVDVTPEALAAGDHHGATYYQLLKFHAALAG
STAPRITATDGVRSVEMGAAAQQSIATGQPVALDFSKGAAA

Sequences:

>Translated_361_residues
MSTHKTYAIIGCGMMGREHMRNIALVDDAELVAIADPDAGSRDLAAKQAAELGQSPVILATTDELFAATSPDAVIVASPN
FTHFDVVQPIMERGCAILLEKPMCTTVEDARALERLVEQYEPLFWVGLEYRYMPPVTRFIERVQAGEAGPVKMLTIREHR
FPFLPKVGDWNRFNCNTGGTLVEKCCHFFDLMRHILQDEPVRIFASGAQDVNHLDESYAGETPDIIDNAYVLVDFAGGAR
AVLDLCMFAEGSQEQEDIYVAGPVGKLEVQLPGGKVIWSPRDRSGPFVEQVDVTPEALAAGDHHGATYYQLLKFHAALAG
STAPRITATDGVRSVEMGAAAQQSIATGQPVALDFSKGAAA
>Mature_360_residues
STHKTYAIIGCGMMGREHMRNIALVDDAELVAIADPDAGSRDLAAKQAAELGQSPVILATTDELFAATSPDAVIVASPNF
THFDVVQPIMERGCAILLEKPMCTTVEDARALERLVEQYEPLFWVGLEYRYMPPVTRFIERVQAGEAGPVKMLTIREHRF
PFLPKVGDWNRFNCNTGGTLVEKCCHFFDLMRHILQDEPVRIFASGAQDVNHLDESYAGETPDIIDNAYVLVDFAGGARA
VLDLCMFAEGSQEQEDIYVAGPVGKLEVQLPGGKVIWSPRDRSGPFVEQVDVTPEALAAGDHHGATYYQLLKFHAALAGS
TAPRITATDGVRSVEMGAAAQQSIATGQPVALDFSKGAAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=190, Percent_Identity=27.3684210526316, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082405, Length=239, Percent_Identity=21.7573221757322, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39180; Mature: 39049

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHKTYAIIGCGMMGREHMRNIALVDDAELVAIADPDAGSRDLAAKQAAELGQSPVILA
CCCCCEEEEEECCHHCHHHHCCEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEE
TTDELFAATSPDAVIVASPNFTHFDVVQPIMERGCAILLEKPMCTTVEDARALERLVEQY
ECHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHC
EPLFWVGLEYRYMPPVTRFIERVQAGEAGPVKMLTIREHRFPFLPKVGDWNRFNCNTGGT
CCEEEEEEEEEECCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCEECCCCCH
LVEKCCHFFDLMRHILQDEPVRIFASGAQDVNHLDESYAGETPDIIDNAYVLVDFAGGAR
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCHHCCCEEEEEECCCHH
AVLDLCMFAEGSQEQEDIYVAGPVGKLEVQLPGGKVIWSPRDRSGPFVEQVDVTPEALAA
HHHHHHHHCCCCCCCCCEEEECCCCEEEEEECCCEEEECCCCCCCCCEEEECCCHHHHHC
GDHHGATYYQLLKFHAALAGSTAPRITATDGVRSVEMGAAAQQSIATGQPVALDFSKGAA
CCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHCHHHHHHHCCCCCEEEECCCCCC
A
C
>Mature Secondary Structure 
STHKTYAIIGCGMMGREHMRNIALVDDAELVAIADPDAGSRDLAAKQAAELGQSPVILA
CCCCEEEEEECCHHCHHHHCCEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEE
TTDELFAATSPDAVIVASPNFTHFDVVQPIMERGCAILLEKPMCTTVEDARALERLVEQY
ECHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHC
EPLFWVGLEYRYMPPVTRFIERVQAGEAGPVKMLTIREHRFPFLPKVGDWNRFNCNTGGT
CCEEEEEEEEEECCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCEECCCCCH
LVEKCCHFFDLMRHILQDEPVRIFASGAQDVNHLDESYAGETPDIIDNAYVLVDFAGGAR
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCHHCCCEEEEEECCCHH
AVLDLCMFAEGSQEQEDIYVAGPVGKLEVQLPGGKVIWSPRDRSGPFVEQVDVTPEALAA
HHHHHHHHCCCCCCCCCEEEECCCCEEEEEECCCEEEECCCCCCCCCEEEECCCHHHHHC
GDHHGATYYQLLKFHAALAGSTAPRITATDGVRSVEMGAAAQQSIATGQPVALDFSKGAA
CCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHCHHHHHHHCCCCCEEEECCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]