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The map label for this gene is qseB [H]

Identifier: 85373556

GI number: 85373556

Start: 752823

End: 753500

Strand: Direct

Name: qseB [H]

Synonym: ELI_03645

Alternate gene names: 85373556

Gene position: 752823-753500 (Clockwise)

Preceding gene: 85373555

Following gene: 85373557

Centisome position: 24.66

GC content: 61.36

Gene sequence:

>678_bases
ATGCGCATCCTGATTGTCGAGGACGAACCGACGCTGGGCCAGCAGCTCAAGAGTACGCTGGAGCAGAACGGTTATGCCGT
GGACTTGTCGACCGATGGCGAGGACGGCCACTTTCTCGGTAGCACCGAAGATTACGATGCCGTGATTCTCGACCTTGGCC
TGCCGGAGATCGACGGGCTGACCGTACTCGGCATGTGGCGCAAGGAAGGCCGCGACTTTCCGGTCCTGGTGCTAACGGCG
CGCGACAGCTGGTCGGACAAGGTGGCAGGTCTCGACGCGGGGGCCGACGATTATCTCGCCAAACCGTTCCAGACCGAGGA
ATTGATCGCGCGGCTACGCGCTTTGATCCGCCGCGCTTCGGGCAACACGTCCAGCGAGCTGACCGCCGGCGATGTCCGGC
TGGACACCCGTTCGGGCCGCGTTTCGCTAAAGGGCGAGCCGGTCAAGCTGACGGCGCAAGAATACAAGCTGCTGAGCTAT
CTGATGCACCACAAGGGCAAGGTGGTCAGCCGTACCGAACTGATCGAGCATATCTACGATCAGGATTTCGACCGCGATTC
CAATACGATCGAGGTTTTTGTAACGCGCATCCGCAAGAAATTGGGCGCAGAAGTGATTACGACGATCCGTGGACTCGGCT
ACAGCCTCGACGACCCGGCCGACGCGCCGCGGGCCTGA

Upstream 100 bases:

>100_bases
CTGGCAAAATTCTCCGGCGGACGCGCTGACCGCTTCCCATTGACGCGATCCCACCAAACGCGCCAATAGGCGAGCGAACT
CAACGGGGACCCGAATTTCT

Downstream 100 bases:

>100_bases
CGACGCGTCCGATGCCGCACTCGAAGAGGGCGCGGTGACTGGCGCGCCGGATACGGGCGACGCCGCGCATCCGCTGACGC
CAGAGGAGCAGGCGGAGGCT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRILIVEDEPTLGQQLKSTLEQNGYAVDLSTDGEDGHFLGSTEDYDAVILDLGLPEIDGLTVLGMWRKEGRDFPVLVLTA
RDSWSDKVAGLDAGADDYLAKPFQTEELIARLRALIRRASGNTSSELTAGDVRLDTRSGRVSLKGEPVKLTAQEYKLLSY
LMHHKGKVVSRTELIEHIYDQDFDRDSNTIEVFVTRIRKKLGAEVITTIRGLGYSLDDPADAPRA

Sequences:

>Translated_225_residues
MRILIVEDEPTLGQQLKSTLEQNGYAVDLSTDGEDGHFLGSTEDYDAVILDLGLPEIDGLTVLGMWRKEGRDFPVLVLTA
RDSWSDKVAGLDAGADDYLAKPFQTEELIARLRALIRRASGNTSSELTAGDVRLDTRSGRVSLKGEPVKLTAQEYKLLSY
LMHHKGKVVSRTELIEHIYDQDFDRDSNTIEVFVTRIRKKLGAEVITTIRGLGYSLDDPADAPRA
>Mature_225_residues
MRILIVEDEPTLGQQLKSTLEQNGYAVDLSTDGEDGHFLGSTEDYDAVILDLGLPEIDGLTVLGMWRKEGRDFPVLVLTA
RDSWSDKVAGLDAGADDYLAKPFQTEELIARLRALIRRASGNTSSELTAGDVRLDTRSGRVSLKGEPVKLTAQEYKLLSY
LMHHKGKVVSRTELIEHIYDQDFDRDSNTIEVFVTRIRKKLGAEVITTIRGLGYSLDDPADAPRA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=45.4128440366972, Blast_Score=188, Evalue=2e-49,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=43.1192660550459, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=39.7321428571429, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1790552, Length=216, Percent_Identity=45.8333333333333, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=39.5454545454545, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=35.1351351351351, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=35.6521739130435, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786911, Length=202, Percent_Identity=38.6138613861386, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=34.3891402714932, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=34.9344978165939, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=30.6666666666667, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=31.8385650224215, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=33.6283185840708, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=26.8398268398268, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=32.7102803738318, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24964; Mature: 24964

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIVEDEPTLGQQLKSTLEQNGYAVDLSTDGEDGHFLGSTEDYDAVILDLGLPEIDGL
CEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCCCEECCCCCCCEEEEECCCCCCCCE
TVLGMWRKEGRDFPVLVLTARDSWSDKVAGLDAGADDYLAKPFQTEELIARLRALIRRAS
EEEEEHHHCCCCCCEEEEEECCCCCCHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHC
GNTSSELTAGDVRLDTRSGRVSLKGEPVKLTAQEYKLLSYLMHHKGKVVSRTELIEHIYD
CCCCCCEEECCEEEECCCCEEEECCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
QDFDRDSNTIEVFVTRIRKKLGAEVITTIRGLGYSLDDPADAPRA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRILIVEDEPTLGQQLKSTLEQNGYAVDLSTDGEDGHFLGSTEDYDAVILDLGLPEIDGL
CEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCCCEECCCCCCCEEEEECCCCCCCCE
TVLGMWRKEGRDFPVLVLTARDSWSDKVAGLDAGADDYLAKPFQTEELIARLRALIRRAS
EEEEEHHHCCCCCCEEEEEECCCCCCHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHC
GNTSSELTAGDVRLDTRSGRVSLKGEPVKLTAQEYKLLSYLMHHKGKVVSRTELIEHIYD
CCCCCCEEECCEEEECCCCEEEECCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
QDFDRDSNTIEVFVTRIRKKLGAEVITTIRGLGYSLDDPADAPRA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]