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The map label for this gene is ucpA [C]

Identifier: 85373290

GI number: 85373290

Start: 504173

End: 504955

Strand: Reverse

Name: ucpA [C]

Synonym: ELI_02315

Alternate gene names: 85373290

Gene position: 504955-504173 (Counterclockwise)

Preceding gene: 85373291

Following gene: 85373287

Centisome position: 16.54

GC content: 65.64

Gene sequence:

>783_bases
ATGGCGAAACTCGACGACAAGCTCTGTGTGGTGACCGGCGGTGCGCGCGGGATTGGCTTTGCGACCTGCAAGGCCTTTCT
CGCCGCAGGTGCGGACGTCATCCTCACCGATATCGACGAAGAGGCCGGACAGGCCGCTGCCAACGAACTCCGTTGCCGTT
TCCACAAGCTCGACGTCCAGCACGAGAGCGACTGGGAGGATCTGGCTGATGCGGCTCCCGCCATCGATGTCCTGTTCAAC
AATGCCGGTATCACCGGTTTCGAGGATAGCCCCGGCCCGCATGACCCGGAGAACGCTTCGCTGGCCGAATGGCGGCGGGT
CCATGCGGTCAATAGCGACGGGACCTTCCTTGGCTGCCGCTATGCGATCCGTGCCATGAAGGCGAAGGGCAGCGGCTCGA
TCATCAACATGTCCTCCCGCTCGGGCCTTGTCGGCATACCCGGCGCGGCGGCCTATGCGGCGAGCAAGGCGGCGATCCGC
AACCACACCAAGTCGGTCGCGCTTTATTGCGCGCAGCAAGGTTGGGCGATCCGTTGCAATTCGATCCACCCGGCCGCGAT
CCTGACCGAGATCTGGGAACCGATGCTGGGCGACGGGCCGGACCGCGAGGCCAAGATGGCGGCGCTGGTCGCAGACACGC
CGCTGAAGCGTTTCGGCACGGTCGAGGAAGTCGCGGCGCTCTGCGTCTATGTCGCCAGCGACGAGAGCGGCTACATGACC
GGTGCCGAGCTCACGCTCGACGGCGGGTTGCTGGCGGGCTCGGCAGCCTCACCCGGCTCCTGA

Upstream 100 bases:

>100_bases
GTCGACGAGGCCTGGATTGCCACAGCGCTTGCTTCGCTGATGGAGCGCATCGGCGGCTAGCGCGATTGCGCGCGGCCTTT
CGCTCCCATATGCGGGGGCG

Downstream 100 bases:

>100_bases
GCCGCTTTCCTCCATGATCATCGGAGCATCGCTGACGGGCGCGCCCCAATTCATCGTTTCGCTCACCCGCACTTCGCCTT
CGCTGCCGCGCAGGCTGAGC

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MAKLDDKLCVVTGGARGIGFATCKAFLAAGADVILTDIDEEAGQAAANELRCRFHKLDVQHESDWEDLADAAPAIDVLFN
NAGITGFEDSPGPHDPENASLAEWRRVHAVNSDGTFLGCRYAIRAMKAKGSGSIINMSSRSGLVGIPGAAAYAASKAAIR
NHTKSVALYCAQQGWAIRCNSIHPAAILTEIWEPMLGDGPDREAKMAALVADTPLKRFGTVEEVAALCVYVASDESGYMT
GAELTLDGGLLAGSAASPGS

Sequences:

>Translated_260_residues
MAKLDDKLCVVTGGARGIGFATCKAFLAAGADVILTDIDEEAGQAAANELRCRFHKLDVQHESDWEDLADAAPAIDVLFN
NAGITGFEDSPGPHDPENASLAEWRRVHAVNSDGTFLGCRYAIRAMKAKGSGSIINMSSRSGLVGIPGAAAYAASKAAIR
NHTKSVALYCAQQGWAIRCNSIHPAAILTEIWEPMLGDGPDREAKMAALVADTPLKRFGTVEEVAALCVYVASDESGYMT
GAELTLDGGLLAGSAASPGS
>Mature_259_residues
AKLDDKLCVVTGGARGIGFATCKAFLAAGADVILTDIDEEAGQAAANELRCRFHKLDVQHESDWEDLADAAPAIDVLFNN
AGITGFEDSPGPHDPENASLAEWRRVHAVNSDGTFLGCRYAIRAMKAKGSGSIINMSSRSGLVGIPGAAAYAASKAAIRN
HTKSVALYCAQQGWAIRCNSIHPAAILTEIWEPMLGDGPDREAKMAALVADTPLKRFGTVEEVAALCVYVASDESGYMTG
AELTLDGGLLAGSAASPGS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=36.6533864541833, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=33.7662337662338, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI15277342, Length=267, Percent_Identity=32.5842696629214, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=30.952380952381, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=28.8461538461538, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=30.5882352941176, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI31542939, Length=207, Percent_Identity=31.8840579710145, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI7705925, Length=259, Percent_Identity=27.7992277992278, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=25.4901960784314, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI83715985, Length=255, Percent_Identity=28.6274509803922, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=28.90625, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI224922801, Length=179, Percent_Identity=32.4022346368715, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI4504505, Length=201, Percent_Identity=30.8457711442786, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=33.8403041825095, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=31.8897637795276, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1790717, Length=264, Percent_Identity=31.4393939393939, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788459, Length=262, Percent_Identity=32.824427480916, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI2367175, Length=267, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=29.3436293436293, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=27.34375, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=27.6264591439689, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=30.6451612903226, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789208, Length=259, Percent_Identity=29.3436293436293, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=30.5220883534137, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=29.0322580645161, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789057, Length=267, Percent_Identity=25.4681647940075, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=35.6862745098039, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17560676, Length=260, Percent_Identity=27.3076923076923, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=32.1705426356589, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=29.6442687747036, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=26.5384615384615, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=28.8537549407115, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=27.3408239700375, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=275, Percent_Identity=27.6363636363636, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=264, Percent_Identity=28.4090909090909, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=27.9527559055118, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357041, Length=262, Percent_Identity=34.3511450381679, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28571526, Length=269, Percent_Identity=32.7137546468402, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=33.0739299610895, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=31.3492063492063, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=30.5882352941176, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=31.0483870967742, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355319, Length=261, Percent_Identity=27.2030651340996, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=30.1158301158301, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24644337, Length=180, Percent_Identity=32.2222222222222, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.51 [H]

Molecular weight: Translated: 27125; Mature: 26994

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLDDKLCVVTGGARGIGFATCKAFLAAGADVILTDIDEEAGQAAANELRCRFHKLDVQ
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHEECCC
HESDWEDLADAAPAIDVLFNNAGITGFEDSPGPHDPENASLAEWRRVHAVNSDGTFLGCR
CCCCHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHEEECCCCCEEHHH
YAIRAMKAKGSGSIINMSSRSGLVGIPGAAAYAASKAAIRNHTKSVALYCAQQGWAIRCN
HHHHHHHCCCCCCEEEECCCCCEEECCCHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEC
SIHPAAILTEIWEPMLGDGPDREAKMAALVADTPLKRFGTVEEVAALCVYVASDESGYMT
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCCHHHHHHHEEEEECCCCCCEE
GAELTLDGGLLAGSAASPGS
CCEEEECCCEEECCCCCCCC
>Mature Secondary Structure 
AKLDDKLCVVTGGARGIGFATCKAFLAAGADVILTDIDEEAGQAAANELRCRFHKLDVQ
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHEECCC
HESDWEDLADAAPAIDVLFNNAGITGFEDSPGPHDPENASLAEWRRVHAVNSDGTFLGCR
CCCCHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHEEECCCCCEEHHH
YAIRAMKAKGSGSIINMSSRSGLVGIPGAAAYAASKAAIRNHTKSVALYCAQQGWAIRCN
HHHHHHHCCCCCCEEEECCCCCEEECCCHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEC
SIHPAAILTEIWEPMLGDGPDREAKMAALVADTPLKRFGTVEEVAALCVYVASDESGYMT
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCCHHHHHHHEEEEECCCCCCEE
GAELTLDGGLLAGSAASPGS
CCEEEECCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8382516; 2026158; 8617258 [H]