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The map label for this gene is surE

Identifier: 85372948

GI number: 85372948

Start: 153695

End: 154453

Strand: Reverse

Name: surE

Synonym: ELI_00605

Alternate gene names: 85372948

Gene position: 154453-153695 (Counterclockwise)

Preceding gene: 85372949

Following gene: 85372947

Centisome position: 5.06

GC content: 62.19

Gene sequence:

>759_bases
ATGCGCATCCTCCTCACCAATGACGACGGCATCCACGCCCCCGGCTTCGAAGTGCTGGAGGACATCGCGCGCGAATTGTC
GGACGAAATCTGGGTTTGTGCTCCAGCAGAAGAACAATCCGGCGCTGGCCACTCGCTGACGCTGCACCACCCGGTGCGGC
TGCGGCAGCTCGGCGAGCGGCGTTATTCGGTCACCGGGACACCCACCGACAGCGTGATGCTGGCGCTGCGCACCGTGCTG
GAAGACAAGCAGCCCGATTTGATCCTCTCCGGCGTCAATCGCGGCGCCAATCTCGGCGACGACATCACCTATTCGGGCAC
TGCCTCGGCAGCGATGGAGGGCGCACTGGGCGGGATCAAGTCGATCGCGCTGAGCCAGGTCTACAAGCGCGATGCCGAGC
ATGAATTGTTCGATGCCGCGCGCACGTACGGCGCCGACGTGATCAGGAAATTGATCGACGCGCCATTTGGCGATCGCACG
CTCATCAACATCAATTTCCCGCCGCTCCCCGCCGATAAAGTGCGCGGAATTCGCGCTGTACGGCAAGGTTTCCACGATTA
TTCGCGTGGTTCGGTGGTCAAGGGGCGTGACCCGCGCGGCCTGGAGTATTACTGGTTCGGTCTCTACGCGATCGAACATA
CGCTCGATCACGGGACCGACCTGGAAGCCATCGACGAGGGATTTGTGTCCGTGACGCCCCTGCAGCTCGACCTCACCCAA
CACTCCCTGCTGTCCGTTATCGGCGAGAGGTTCGAGTGA

Upstream 100 bases:

>100_bases
TGTCGAAGCCCTGTCCTTCCCTTGAGAGCAACGTACGTAAGAAAGAGCAGCCCTTCGACAGGCTCAGGGCGAACGGAATA
GAGAGAGCAGGTCCAAAATC

Downstream 100 bases:

>100_bases
TGCGCCGCGCGGCTCTCCTCCTTCTCGCCGCGCCGCTGCTGCTGGCAGCGAACAATCCCAGGACGGCGACCGAATATGAG
GTCCAGACGGGCGATACGCT

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MRILLTNDDGIHAPGFEVLEDIARELSDEIWVCAPAEEQSGAGHSLTLHHPVRLRQLGERRYSVTGTPTDSVMLALRTVL
EDKQPDLILSGVNRGANLGDDITYSGTASAAMEGALGGIKSIALSQVYKRDAEHELFDAARTYGADVIRKLIDAPFGDRT
LININFPPLPADKVRGIRAVRQGFHDYSRGSVVKGRDPRGLEYYWFGLYAIEHTLDHGTDLEAIDEGFVSVTPLQLDLTQ
HSLLSVIGERFE

Sequences:

>Translated_252_residues
MRILLTNDDGIHAPGFEVLEDIARELSDEIWVCAPAEEQSGAGHSLTLHHPVRLRQLGERRYSVTGTPTDSVMLALRTVL
EDKQPDLILSGVNRGANLGDDITYSGTASAAMEGALGGIKSIALSQVYKRDAEHELFDAARTYGADVIRKLIDAPFGDRT
LININFPPLPADKVRGIRAVRQGFHDYSRGSVVKGRDPRGLEYYWFGLYAIEHTLDHGTDLEAIDEGFVSVTPLQLDLTQ
HSLLSVIGERFE
>Mature_252_residues
MRILLTNDDGIHAPGFEVLEDIARELSDEIWVCAPAEEQSGAGHSLTLHHPVRLRQLGERRYSVTGTPTDSVMLALRTVL
EDKQPDLILSGVNRGANLGDDITYSGTASAAMEGALGGIKSIALSQVYKRDAEHELFDAARTYGADVIRKLIDAPFGDRT
LININFPPLPADKVRGIRAVRQGFHDYSRGSVVKGRDPRGLEYYWFGLYAIEHTLDHGTDLEAIDEGFVSVTPLQLDLTQ
HSLLSVIGERFE

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=250, Percent_Identity=41.2, Blast_Score=182, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_ERYLH (Q2NDM8)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_457010.1
- ProteinModelPortal:   Q2NDM8
- SMR:   Q2NDM8
- STRING:   Q2NDM8
- GeneID:   3870998
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_00605
- NMPDR:   fig|314225.3.peg.2971
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- PhylomeDB:   Q2NDM8
- ProtClustDB:   PRK00346
- BioCyc:   ELIT314225:ELI_00605-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 27751; Mature: 27751

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLTNDDGIHAPGFEVLEDIARELSDEIWVCAPAEEQSGAGHSLTLHHPVRLRQLGER
CEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCHHHHHHHHH
RYSVTGTPTDSVMLALRTVLEDKQPDLILSGVNRGANLGDDITYSGTASAAMEGALGGIK
CEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEECCCHHHHHHHHHHHHH
SIALSQVYKRDAEHELFDAARTYGADVIRKLIDAPFGDRTLININFPPLPADKVRGIRAV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHH
RQGFHDYSRGSVVKGRDPRGLEYYWFGLYAIEHTLDHGTDLEAIDEGFVSVTPLQLDLTQ
HHHHHHHCCCCEECCCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHCCCEEECEEEEEHHH
HSLLSVIGERFE
HHHHHHHHHHCC
>Mature Secondary Structure
MRILLTNDDGIHAPGFEVLEDIARELSDEIWVCAPAEEQSGAGHSLTLHHPVRLRQLGER
CEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCHHHHHHHHH
RYSVTGTPTDSVMLALRTVLEDKQPDLILSGVNRGANLGDDITYSGTASAAMEGALGGIK
CEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEECCCHHHHHHHHHHHHH
SIALSQVYKRDAEHELFDAARTYGADVIRKLIDAPFGDRTLININFPPLPADKVRGIRAV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHH
RQGFHDYSRGSVVKGRDPRGLEYYWFGLYAIEHTLDHGTDLEAIDEGFVSVTPLQLDLTQ
HHHHHHHCCCCEECCCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHCCCEEECEEEEEHHH
HSLLSVIGERFE
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA