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The map label for this gene is arsC [H]

Identifier: 85372905

GI number: 85372905

Start: 104968

End: 105354

Strand: Direct

Name: arsC [H]

Synonym: ELI_00390

Alternate gene names: 85372905

Gene position: 104968-105354 (Clockwise)

Preceding gene: 85372903

Following gene: 85372907

Centisome position: 3.44

GC content: 59.17

Gene sequence:

>387_bases
TTGACCAATGCAATCGATCATAGCAAAGGCCTGACAATCCCCATGAAAGCGACCATCTGGCACAACCCGAAATGCGGCAC
CTCACGCAAGACCCTCGCGATCCTTGAGAACCTGTCGAAGGTCGAACTTACCGTGGTCGAGTATCTCAAGGAGCCACCGA
CGGCGGATAAGCTGCGTCAGCTTTACACGGACGCCGGAATTGTGCCGAACGAAGGGCTCCGCCTGCGCGGCACCGATGCG
GAGGAGCGCGGCCTGCCGGACGCCGATGCCGAAAGCGTGCTGGCGGCGATGGTGGCAGATCCGATCCTTATCAACCGCCC
GCTCGTAGAAACCGAGAAGGGCGTGCGTCTGTGCCGTCCTCAGGATACCGTACTTGAAATTCTTTAG

Upstream 100 bases:

>100_bases
TTGCGAACGATTCTCGATTGATGCAGGCCTGCTATTGAGAATAAGTCGCAATTGCAACCAGCAATCGGGCTTGGCGGAAA
AATTGTCGCTTGCTAGGGTT

Downstream 100 bases:

>100_bases
CCCCGATCGATCGTCAGGTAGTCGTCGCTTTGCAGCGAGCGATAGCCGAGCACGAAGACGGCGAGGCAGAAGCCGATGAT
GACGGCGAAGCCGAGCCAGT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MTNAIDHSKGLTIPMKATIWHNPKCGTSRKTLAILENLSKVELTVVEYLKEPPTADKLRQLYTDAGIVPNEGLRLRGTDA
EERGLPDADAESVLAAMVADPILINRPLVETEKGVRLCRPQDTVLEIL

Sequences:

>Translated_128_residues
MTNAIDHSKGLTIPMKATIWHNPKCGTSRKTLAILENLSKVELTVVEYLKEPPTADKLRQLYTDAGIVPNEGLRLRGTDA
EERGLPDADAESVLAAMVADPILINRPLVETEKGVRLCRPQDTVLEIL
>Mature_127_residues
TNAIDHSKGLTIPMKATIWHNPKCGTSRKTLAILENLSKVELTVVEYLKEPPTADKLRQLYTDAGIVPNEGLRLRGTDAE
ERGLPDADAESVLAAMVADPILINRPLVETEKGVRLCRPQDTVLEIL

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=113, Percent_Identity=47.787610619469, Blast_Score=94, Evalue=3e-21,
Organism=Escherichia coli, GI1788841, Length=116, Percent_Identity=37.0689655172414, Blast_Score=63, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 14084; Mature: 13953

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNAIDHSKGLTIPMKATIWHNPKCGTSRKTLAILENLSKVELTVVEYLKEPPTADKLRQ
CCCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHH
LYTDAGIVPNEGLRLRGTDAEERGLPDADAESVLAAMVADPILINRPLVETEKGVRLCRP
HHHHCCCCCCCCEEEECCCHHHCCCCCCCHHHHHHHHHHCCHHCCCCCCCCCCCCEEECC
QDTVLEIL
CHHHHHCC
>Mature Secondary Structure 
TNAIDHSKGLTIPMKATIWHNPKCGTSRKTLAILENLSKVELTVVEYLKEPPTADKLRQ
CCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHH
LYTDAGIVPNEGLRLRGTDAEERGLPDADAESVLAAMVADPILINRPLVETEKGVRLCRP
HHHHCCCCCCCCEEEECCCHHHCCCCCCCHHHHHHHHHHCCHHCCCCCCCCCCCCEEECC
QDTVLEIL
CHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006011 [H]