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The map label for this gene is bcd [H]

Identifier: 85372886

GI number: 85372886

Start: 80659

End: 81870

Strand: Direct

Name: bcd [H]

Synonym: ELI_00295

Alternate gene names: 85372886

Gene position: 80659-81870 (Clockwise)

Preceding gene: 85372885

Following gene: 85372887

Centisome position: 2.64

GC content: 61.72

Gene sequence:

>1212_bases
ATGGCGACCGCAGCCGACACCCGCCCGGAAGACGATCTCGATGCCTTCCGCGCCGAAGTGAAGGACTTCCTCAAGGCCAG
TTTCCCCGACAGCCTCAAGGGCAAGGGCAATGTCATGCGCACGGTCGAAGGGCCGGGCGAAGAAACGCCGGAAGAAAAGG
CCTGGCGCGAGGCCATGGGCGAGAAAGGCTGGGGCACTCCGACCTGGCCCAAAGAGTATAATGGCGGCGGCCTGACCAAG
AAGCAGGCCAAGGTGCTCGAGCAGGAAATGGCCATGGCCGGGGCCTGGAACCCGATCGGCGGCATGGGCGTGATGATGTT
CGGCCCGACGCTGCTCGAGTTCGGCAGCCACGAACAAAAGCTCGAACATATCCCGCCGATCACCCGCGGCGAAGTACGCT
GGTGCCAAGGCTATTCGGAGCCGAATGCCGGTTCGGATCTTGCCAGCTTGCAGACCAGCGCCGAGGACAAGGGCGATCAC
TATCTCGTCAATGGCCAGAAGACCTGGACCAGCGGCGGGCAGTGGGCGGACAAATGCTTCTGCCTTGTCCGCACCGACCG
CAGCGACAAGCACAAGGGCATTTCCTTCCTGCTGATCGACATGGACTCGCCCGGCGTCGACGTGAAGCCGATCACTATGA
TCAGCGGCATGAGCCCGTTTTGCGAGACCTTCTTCACCGATGTGAAGGTGCCGAAGGAAAACCTCGTCGGCGAAGAAGGG
CAGGGCTGGACCATCGGCAAGCGCCTGCTCCAGCACGAACGGACCAATATCTCCGGTGGTGGAGCGCTCGCGGCGCTCAA
TGCCCAGCCGCTTTCCAAGATTGCCGAGCATTATCTCGGCACCGACGAACAGGGCCGGCTCAATGACCCGGAAATGCGGG
CAAAGATCGCCGAATTCGAAATGGCGTGGAACACCTTCCTCCTCACCGCGCGCCGCGCGATGGAGGAAAGCAAGGCGCAG
GGCGGCGTTTCGGAGATCAGTTCGATCCTCAAGAATGTCGGCTCCAAGCTGGGCCAGCAGCGCGCCGAATTGCTGATCGA
GATCATGGGCTTCCGCGGCCTCGGCTGGGAAGGCGAAGGCTTTACGGATAAGGAACTGCAGCATGTCCGCGGCTGGCTCT
TCGGCAAGGCGACCACGATCTATGGCGGCTCGACCGAAATCCAGAACAACATCATCGCCAAGCGTATCCTTGGCATGCTG
GACCACCAGTAA

Upstream 100 bases:

>100_bases
ACGCCTTCCGCTACGTCAGCATGGACCACAGGCCCCCTGTTCTCGGCCCTTTGACTCGTGCATAGGTGGCAAAACAAGAC
TCATAAGCAGGAGAGAAGCG

Downstream 100 bases:

>100_bases
GCGCGGGCGCAGGGACAGGACGAAACATCATGGCAGTGCTGAACGAAGAACAGACCATGCTGCGCGACATGGCGCAGGAA
TGGACGAAGAACGAAAGCCC

Product: acyl-CoA dehydrogenase family protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MATAADTRPEDDLDAFRAEVKDFLKASFPDSLKGKGNVMRTVEGPGEETPEEKAWREAMGEKGWGTPTWPKEYNGGGLTK
KQAKVLEQEMAMAGAWNPIGGMGVMMFGPTLLEFGSHEQKLEHIPPITRGEVRWCQGYSEPNAGSDLASLQTSAEDKGDH
YLVNGQKTWTSGGQWADKCFCLVRTDRSDKHKGISFLLIDMDSPGVDVKPITMISGMSPFCETFFTDVKVPKENLVGEEG
QGWTIGKRLLQHERTNISGGGALAALNAQPLSKIAEHYLGTDEQGRLNDPEMRAKIAEFEMAWNTFLLTARRAMEESKAQ
GGVSEISSILKNVGSKLGQQRAELLIEIMGFRGLGWEGEGFTDKELQHVRGWLFGKATTIYGGSTEIQNNIIAKRILGML
DHQ

Sequences:

>Translated_403_residues
MATAADTRPEDDLDAFRAEVKDFLKASFPDSLKGKGNVMRTVEGPGEETPEEKAWREAMGEKGWGTPTWPKEYNGGGLTK
KQAKVLEQEMAMAGAWNPIGGMGVMMFGPTLLEFGSHEQKLEHIPPITRGEVRWCQGYSEPNAGSDLASLQTSAEDKGDH
YLVNGQKTWTSGGQWADKCFCLVRTDRSDKHKGISFLLIDMDSPGVDVKPITMISGMSPFCETFFTDVKVPKENLVGEEG
QGWTIGKRLLQHERTNISGGGALAALNAQPLSKIAEHYLGTDEQGRLNDPEMRAKIAEFEMAWNTFLLTARRAMEESKAQ
GGVSEISSILKNVGSKLGQQRAELLIEIMGFRGLGWEGEGFTDKELQHVRGWLFGKATTIYGGSTEIQNNIIAKRILGML
DHQ
>Mature_402_residues
ATAADTRPEDDLDAFRAEVKDFLKASFPDSLKGKGNVMRTVEGPGEETPEEKAWREAMGEKGWGTPTWPKEYNGGGLTKK
QAKVLEQEMAMAGAWNPIGGMGVMMFGPTLLEFGSHEQKLEHIPPITRGEVRWCQGYSEPNAGSDLASLQTSAEDKGDHY
LVNGQKTWTSGGQWADKCFCLVRTDRSDKHKGISFLLIDMDSPGVDVKPITMISGMSPFCETFFTDVKVPKENLVGEEGQ
GWTIGKRLLQHERTNISGGGALAALNAQPLSKIAEHYLGTDEQGRLNDPEMRAKIAEFEMAWNTFLLTARRAMEESKAQG
GVSEISSILKNVGSKLGQQRAELLIEIMGFRGLGWEGEGFTDKELQHVRGWLFGKATTIYGGSTEIQNNIIAKRILGMLD
HQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=355, Percent_Identity=28.7323943661972, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI4557231, Length=353, Percent_Identity=27.1954674220963, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI187960098, Length=353, Percent_Identity=27.1954674220963, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI226958414, Length=225, Percent_Identity=31.5555555555556, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI226958412, Length=211, Percent_Identity=31.7535545023697, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4501859, Length=357, Percent_Identity=27.1708683473389, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI7656849, Length=263, Percent_Identity=29.6577946768061, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4557235, Length=368, Percent_Identity=26.3586956521739, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI76496475, Length=368, Percent_Identity=26.3586956521739, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI21361497, Length=353, Percent_Identity=28.0453257790368, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI211971008, Length=301, Percent_Identity=27.2425249169435, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI48976061, Length=301, Percent_Identity=27.2425249169435, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI38505218, Length=145, Percent_Identity=33.1034482758621, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI4501857, Length=403, Percent_Identity=23.5732009925558, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI87081958, Length=386, Percent_Identity=22.020725388601, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786223, Length=174, Percent_Identity=26.4367816091954, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569725, Length=344, Percent_Identity=25.8720930232558, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17534899, Length=348, Percent_Identity=25.8620689655172, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=407, Percent_Identity=25.0614250614251, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538396, Length=209, Percent_Identity=30.1435406698565, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=334, Percent_Identity=27.5449101796407, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=214, Percent_Identity=30.3738317757009, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17508101, Length=338, Percent_Identity=27.5147928994083, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=213, Percent_Identity=31.4553990610329, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17533517, Length=275, Percent_Identity=28.7272727272727, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=192, Percent_Identity=28.6458333333333, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71985184, Length=222, Percent_Identity=31.5315315315315, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=222, Percent_Identity=31.5315315315315, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=193, Percent_Identity=27.979274611399, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=209, Percent_Identity=26.7942583732057, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21356377, Length=359, Percent_Identity=31.4763231197772, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646207, Length=369, Percent_Identity=29.2682926829268, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24666513, Length=293, Percent_Identity=26.962457337884, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355753, Length=155, Percent_Identity=36.1290322580645, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24660351, Length=298, Percent_Identity=27.5167785234899, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281363737, Length=225, Percent_Identity=27.5555555555556, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 44359; Mature: 44228

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAADTRPEDDLDAFRAEVKDFLKASFPDSLKGKGNVMRTVEGPGEETPEEKAWREAMG
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHC
EKGWGTPTWPKEYNGGGLTKKQAKVLEQEMAMAGAWNPIGGMGVMMFGPTLLEFGSHEQK
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHH
LEHIPPITRGEVRWCQGYSEPNAGSDLASLQTSAEDKGDHYLVNGQKTWTSGGQWADKCF
HHHCCCCCCCCHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCEECCCCCCHHHHEE
CLVRTDRSDKHKGISFLLIDMDSPGVDVKPITMISGMSPFCETFFTDVKVPKENLVGEEG
EEEECCCCCCCCCEEEEEEECCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCHHHCCCCCC
QGWTIGKRLLQHERTNISGGGALAALNAQPLSKIAEHYLGTDEQGRLNDPEMRAKIAEFE
CCHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
MAWNTFLLTARRAMEESKAQGGVSEISSILKNVGSKLGQQRAELLIEIMGFRGLGWEGEG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
FTDKELQHVRGWLFGKATTIYGGSTEIQNNIIAKRILGMLDHQ
CCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATAADTRPEDDLDAFRAEVKDFLKASFPDSLKGKGNVMRTVEGPGEETPEEKAWREAMG
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHC
EKGWGTPTWPKEYNGGGLTKKQAKVLEQEMAMAGAWNPIGGMGVMMFGPTLLEFGSHEQK
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHH
LEHIPPITRGEVRWCQGYSEPNAGSDLASLQTSAEDKGDHYLVNGQKTWTSGGQWADKCF
HHHCCCCCCCCHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCEECCCCCCHHHHEE
CLVRTDRSDKHKGISFLLIDMDSPGVDVKPITMISGMSPFCETFFTDVKVPKENLVGEEG
EEEECCCCCCCCCEEEEEEECCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCHHHCCCCCC
QGWTIGKRLLQHERTNISGGGALAALNAQPLSKIAEHYLGTDEQGRLNDPEMRAKIAEFE
CCHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
MAWNTFLLTARRAMEESKAQGGVSEISSILKNVGSKLGQQRAELLIEIMGFRGLGWEGEG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
FTDKELQHVRGWLFGKATTIYGGSTEIQNNIIAKRILGMLDHQ
CCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]