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The map label for this gene is mmgC [H]

Identifier: 85372839

GI number: 85372839

Start: 21572

End: 22714

Strand: Direct

Name: mmgC [H]

Synonym: ELI_00060

Alternate gene names: 85372839

Gene position: 21572-22714 (Clockwise)

Preceding gene: 85372838

Following gene: 85372840

Centisome position: 0.71

GC content: 62.29

Gene sequence:

>1143_bases
ATGCTCGATACCTCCCAACGCTTCGCCTATAATGAAGACCACGAGATGTTCCGCGACACCGTGCGCAAGGTCTTCTCGCA
GCATCTCGAACCGCATCTCGACGAACACGAGGAAAAGGGCATCGTCCCGCGCGAGATCTGGAAAGCGGTCGGCGAAGCGG
GCCTGCTGTGCCCCACGGTCAAGGAAGAGAACGGCGGGCTGGGGCTCGATTTCGGCTTCAACTGCGTATTGTGCGAGGAA
CTGAGCTACATCGGCTCCTCCGCCGGTTTCACGCTGCAGAGCGATATCACCGCCAATTACATCGAGCGCCTCGGCAGCGA
CGAACAGCGCGCCAAATACCTGCCCGGCATGGTCAGCGGCGATGTCATCACCGCCATCGCTATGACTGAGCCGGGCGCGG
GCTCCGACTTGCAGGGCATCCGCACCACCGCGATCGAGGATGGCAACCACTTGGTCATCAACGGCTCCAAAACCTACATC
ACCAATGGCCAGAATGCCGACGTGGTGATCGTCGTTGCCAAGACCGACCCATCGCAGGGCGCGAAGGGCACCAGCCTCGT
GCTGGTCGATGCCGACACGCCGGGTTTCGAGCGCGGGCGCAACCTCGACAAGATCGGCCAGCATTCCGCCGACACGAGCG
AGCTGTTCTTCAACGATTGCCGCGTGCCCAAGACCAATATCCTAGGGCAAGAAGGCCGCGGCTTCATCCACCTGATGGAA
GAGCTGCCGCAGGAACGCTTGGGCATCGCGGTCGGCGCACAGGCCGCCGCCCAGCGCGCTTTCGACGAAGCGGTCAAATT
CACCAAGGACCGCAAGGCCTTTGGCCAGACCGTGTTCGAATTCCAGAACACCAAGTTCACGCTCGCCGACCTGAAGGCCG
AGCTACAGGTCGGCTGGGCGCATCTCGACTGGGCCATCAAGCGGCACCTTGCGGGCGAACTCACCACCGAGGAAGCCTCC
GCCGCCAAGCTGTGGCACACCGACCTGCAATGGAAAGCCGTCGACACCTCGCTCCAGCTCCACGGCGGCGCGGGCTATAT
GAACGAATACACGATCGCGCGGCTGTGGCGCGACGCCCGCGTGACGCGCATCTTCGGCGGAACGAACGAGATTATGAAAG
AAGTCATCTCGCGGGGGATTTGA

Upstream 100 bases:

>100_bases
TGCGATCCTCAGCTCGCTGGGGATCGAAGCCGACGAAGCCGCTGCCCTGCGCGACGCGGGCACTGTGGGCTGACGCACCG
AACAACCAAGGACCAATCCG

Downstream 100 bases:

>100_bases
GATCGGTCAGTACCATTCCGCATCATGTGCCCCGAACTTTACAAATTAGGGGATACACCCCGAAAAATACGAGGGCCGTG
CACTTAATTCGCCGAGCGCA

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MLDTSQRFAYNEDHEMFRDTVRKVFSQHLEPHLDEHEEKGIVPREIWKAVGEAGLLCPTVKEENGGLGLDFGFNCVLCEE
LSYIGSSAGFTLQSDITANYIERLGSDEQRAKYLPGMVSGDVITAIAMTEPGAGSDLQGIRTTAIEDGNHLVINGSKTYI
TNGQNADVVIVVAKTDPSQGAKGTSLVLVDADTPGFERGRNLDKIGQHSADTSELFFNDCRVPKTNILGQEGRGFIHLME
ELPQERLGIAVGAQAAAQRAFDEAVKFTKDRKAFGQTVFEFQNTKFTLADLKAELQVGWAHLDWAIKRHLAGELTTEEAS
AAKLWHTDLQWKAVDTSLQLHGGAGYMNEYTIARLWRDARVTRIFGGTNEIMKEVISRGI

Sequences:

>Translated_380_residues
MLDTSQRFAYNEDHEMFRDTVRKVFSQHLEPHLDEHEEKGIVPREIWKAVGEAGLLCPTVKEENGGLGLDFGFNCVLCEE
LSYIGSSAGFTLQSDITANYIERLGSDEQRAKYLPGMVSGDVITAIAMTEPGAGSDLQGIRTTAIEDGNHLVINGSKTYI
TNGQNADVVIVVAKTDPSQGAKGTSLVLVDADTPGFERGRNLDKIGQHSADTSELFFNDCRVPKTNILGQEGRGFIHLME
ELPQERLGIAVGAQAAAQRAFDEAVKFTKDRKAFGQTVFEFQNTKFTLADLKAELQVGWAHLDWAIKRHLAGELTTEEAS
AAKLWHTDLQWKAVDTSLQLHGGAGYMNEYTIARLWRDARVTRIFGGTNEIMKEVISRGI
>Mature_380_residues
MLDTSQRFAYNEDHEMFRDTVRKVFSQHLEPHLDEHEEKGIVPREIWKAVGEAGLLCPTVKEENGGLGLDFGFNCVLCEE
LSYIGSSAGFTLQSDITANYIERLGSDEQRAKYLPGMVSGDVITAIAMTEPGAGSDLQGIRTTAIEDGNHLVINGSKTYI
TNGQNADVVIVVAKTDPSQGAKGTSLVLVDADTPGFERGRNLDKIGQHSADTSELFFNDCRVPKTNILGQEGRGFIHLME
ELPQERLGIAVGAQAAAQRAFDEAVKFTKDRKAFGQTVFEFQNTKFTLADLKAELQVGWAHLDWAIKRHLAGELTTEEAS
AAKLWHTDLQWKAVDTSLQLHGGAGYMNEYTIARLWRDARVTRIFGGTNEIMKEVISRGI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=384, Percent_Identity=46.09375, Blast_Score=327, Evalue=1e-89,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=34.5744680851064, Blast_Score=234, Evalue=8e-62,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=35.1032448377581, Blast_Score=222, Evalue=4e-58,
Organism=Homo sapiens, GI187960098, Length=380, Percent_Identity=34.4736842105263, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI4557231, Length=380, Percent_Identity=34.4736842105263, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=36, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=29.4906166219839, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI7656849, Length=381, Percent_Identity=31.2335958005249, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI21361497, Length=371, Percent_Identity=32.6145552560647, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI76496475, Length=396, Percent_Identity=31.5656565656566, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4557235, Length=396, Percent_Identity=31.5656565656566, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4503943, Length=379, Percent_Identity=27.7044854881267, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI7669494, Length=353, Percent_Identity=28.328611898017, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI48976061, Length=293, Percent_Identity=29.6928327645051, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI211971008, Length=293, Percent_Identity=29.6928327645051, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI38505218, Length=305, Percent_Identity=27.5409836065574, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI87081958, Length=379, Percent_Identity=31.3984168865435, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI1786223, Length=374, Percent_Identity=27.807486631016, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI87082384, Length=288, Percent_Identity=26.7361111111111, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=377, Percent_Identity=34.7480106100796, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17551932, Length=380, Percent_Identity=33.6842105263158, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=32.5459317585302, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=34.8167539267016, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=33.8666666666667, Blast_Score=209, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17534899, Length=354, Percent_Identity=34.180790960452, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17533517, Length=362, Percent_Identity=32.8729281767956, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=30.7277628032345, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17506239, Length=373, Percent_Identity=31.3672922252011, Blast_Score=187, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI71990804, Length=276, Percent_Identity=34.0579710144928, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI71985184, Length=359, Percent_Identity=30.08356545961, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71982178, Length=276, Percent_Identity=31.8840579710145, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI32563615, Length=227, Percent_Identity=36.1233480176211, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71985192, Length=270, Percent_Identity=30.7407407407407, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17534353, Length=341, Percent_Identity=25.8064516129032, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=27.3858921161826, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17562446, Length=337, Percent_Identity=28.1899109792285, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI86563383, Length=268, Percent_Identity=27.2388059701493, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI86563381, Length=268, Percent_Identity=27.2388059701493, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=34.4736842105263, Blast_Score=214, Evalue=8e-56,
Organism=Drosophila melanogaster, GI21355753, Length=381, Percent_Identity=33.8582677165354, Blast_Score=211, Evalue=8e-55,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=32.5333333333333, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24666513, Length=371, Percent_Identity=31.266846361186, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=31.5508021390374, Blast_Score=187, Evalue=8e-48,
Organism=Drosophila melanogaster, GI281363737, Length=340, Percent_Identity=32.0588235294118, Blast_Score=164, Evalue=9e-41,
Organism=Drosophila melanogaster, GI19920834, Length=376, Percent_Identity=28.1914893617021, Blast_Score=118, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41906; Mature: 41906

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDTSQRFAYNEDHEMFRDTVRKVFSQHLEPHLDEHEEKGIVPREIWKAVGEAGLLCPTV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHCCCCCCCCCC
KEENGGLGLDFGFNCVLCEELSYIGSSAGFTLQSDITANYIERLGSDEQRAKYLPGMVSG
CCCCCCEEECCCCCEEEEHHHHHHCCCCCCEEECCCHHHHHHHHCCCHHHHHHCCCCCCC
DVITAIAMTEPGAGSDLQGIRTTAIEDGNHLVINGSKTYITNGQNADVVIVVAKTDPSQG
CEEEEEEEECCCCCCCCCCCEEEEEECCCEEEEECCEEEEECCCCCCEEEEEEECCCCCC
AKGTSLVLVDADTPGFERGRNLDKIGQHSADTSELFFNDCRVPKTNILGQEGRGFIHLME
CCCCEEEEEECCCCCHHHCCCHHHHCCCCCCHHHHHHHCCCCCHHCCCCCCCCHHHHHHH
ELPQERLGIAVGAQAAAQRAFDEAVKFTKDRKAFGQTVFEFQNTKFTLADLKAELQVGWA
HCCHHHHCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHEECHH
HLDWAIKRHLAGELTTEEASAAKLWHTDLQWKAVDTSLQLHGGAGYMNEYTIARLWRDAR
HHHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEECCEEEEECCCCCCHHHHHHHHHHHHH
VTRIFGGTNEIMKEVISRGI
EEEEECCHHHHHHHHHHCCC
>Mature Secondary Structure
MLDTSQRFAYNEDHEMFRDTVRKVFSQHLEPHLDEHEEKGIVPREIWKAVGEAGLLCPTV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHCCCCCCCCCC
KEENGGLGLDFGFNCVLCEELSYIGSSAGFTLQSDITANYIERLGSDEQRAKYLPGMVSG
CCCCCCEEECCCCCEEEEHHHHHHCCCCCCEEECCCHHHHHHHHCCCHHHHHHCCCCCCC
DVITAIAMTEPGAGSDLQGIRTTAIEDGNHLVINGSKTYITNGQNADVVIVVAKTDPSQG
CEEEEEEEECCCCCCCCCCCEEEEEECCCEEEEECCEEEEECCCCCCEEEEEEECCCCCC
AKGTSLVLVDADTPGFERGRNLDKIGQHSADTSELFFNDCRVPKTNILGQEGRGFIHLME
CCCCEEEEEECCCCCHHHCCCHHHHCCCCCCHHHHHHHCCCCCHHCCCCCCCCHHHHHHH
ELPQERLGIAVGAQAAAQRAFDEAVKFTKDRKAFGQTVFEFQNTKFTLADLKAELQVGWA
HCCHHHHCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHEECHH
HLDWAIKRHLAGELTTEEASAAKLWHTDLQWKAVDTSLQLHGGAGYMNEYTIARLWRDAR
HHHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEECCEEEEECCCCCCHHHHHHHHHHHHH
VTRIFGGTNEIMKEVISRGI
EEEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]