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The map label for this gene is yngJ [H]

Identifier: 85372834

GI number: 85372834

Start: 13421

End: 15073

Strand: Direct

Name: yngJ [H]

Synonym: ELI_00035

Alternate gene names: 85372834

Gene position: 13421-15073 (Clockwise)

Preceding gene: 85372833

Following gene: 85372837

Centisome position: 0.44

GC content: 65.64

Gene sequence:

>1653_bases
ATGAGCGAATGGATCGACCTGGCGAGGCAGGCGTGCGCAGCCGCGCGCGATTTTGCCGAAGCTGCGCGGGTAGTTGCGGC
AGTAGCGGTCGCGCCTGAGGGCAGGCCCGATCCTGTCTTGGTCGAGCGCGAGCAACGGCTGGTGCATGGTTATGCCTGGA
TCGGCACCACCGTCGCCGCGCTCGAAGCCACCGCCGATTGGGCCAGCCGTGCCGAGGCAGCCGGGCGCTTTGTCGACGTC
GACGAATTGGTCCTGAAGATCGGGTTCGGAGAATATCTACACCAGCTCGCCAGCGGCGTGCCGATGAGCCAGAACGAGAT
CGTCCGTCCCGGCGAATTGGGGCTCGACCGGGCAGCGTCCACGCTTTGCGACAACACCGCCACCGCGCGCTTTATGACCG
AGGGAAACACGGCCGCCAACCGCACCAAGCTCGCAGTCCTGCTTGCCGAAGGTGCACGGCCCGACGAAGCTTTCGGCGAC
GAAACGCTCGACCTGATCCGCGAACAGTTCCGCGCCTTCACTGCCGACAAGATCACGCCTCACGCCCATCAATGGCACAT
GGACGATGCGTTGATCCCGATGGAGGTCGTGCAGGAAATGGCCGCACTGGGCGTCTTCGGCGTCTGTATCGCCGAGAAAC
ACGGCGGGCTGGGGCTCGGCAAGACGGCCATGTGCCTCGTGTCCGAAGAACTCTCGCGCGGCTGGATATGCGCCGGTTCG
CTCGGCACGCGCTCGGAAATCGCGGGCGAGCTGATCGGCGAGAATGGTACGGCGGAGCAGAAGGCGAAGTTCTTGCCACA
AATCGCGGATGGTTCGATCCTGCCCACGGCGGTCTTTACCGAGCCCGATACCGGCTCCGACCTCGCCTCGGTCCGCATGC
GCGGGGTGCGGCAGGCCGACGGGTCGTGGCAGGTGAGCGGTGCCAAGACCTGGATCACCCATGCCGCCCGTGCGGACCTG
ATGACGATGCTGGTGCGCACCGATCCGGGCACACCGGGCTATGGTGGCCTCTCCATGTTGCTGGCGGAGAAAACGCGCGG
CACTGATGCCGATCCGTTTCCCGATACAGGGATAGACGGCAGCGAGATCGAAGTGCTCGGCTATCGCGGGATGAAGGAAT
ATGCGCTCGGTTTCGATGGCTTCGCCGTCGCCGCCGACGGTCTGCTGGGCGGTGCCGAAGGGCAGGGCTTCAAGCAGCTT
ATGCGCACGTTCGAAGGCGCCCGCATCCAGACCGCCGCCCGCGCGATCGGGGTGGCGTGGAATGCTTTCGACCTGGGCCT
GCAATATGCGCTCGAACGCAAGCAGTTCGGCAAGCCGCTGCTCGCCTTCCCGCGCGTGGCGGACAAGCTGGCGCTGATGG
TCGCCGAACTCGTGCTGGCGCGAGAACTCACTTACTCGGCCGCCCGCCACAAGGACAAGGGCGATCGCTGCGATATCGAG
GCCGGTCAAGCCAAGCTGCTCGCCGCGCGCACCGCCTGGTCCAACGCCGACAACGCGCTGCAAATCCACGGCGGCAATGG
CTATGCGCTCGAATACCCGATCAGCCGCGTGCTGTGCGACGCGCGCATCCTCAACATCTTCGAAGGCGCGGGCGAAATCC
AGGCGCAGGTCATCGGTCGCGGGACGCTAAAGGCTCAACCCTCCGCCGCCTGA

Upstream 100 bases:

>100_bases
CGATGACCCGAGAGAGTGCTTGGGCTCGATACCGTCCGACGGCCCGCTTGACCCGGGGTCGGGCCGCACTAATGCCGGTG
GCAATGCGAAACGGCACGGC

Downstream 100 bases:

>100_bases
TCGGGCAGCAACACCACGGTCTCCGGCGTGTCGCTTCCGGTATGCGTCATGGTGAGCGACAGGCGGTCGCGGATGTCGAG
CTTGGCGCGGAGCGCGAGGA

Product: acyl-CoA dehydrogenase, putative

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MSEWIDLARQACAAARDFAEAARVVAAVAVAPEGRPDPVLVEREQRLVHGYAWIGTTVAALEATADWASRAEAAGRFVDV
DELVLKIGFGEYLHQLASGVPMSQNEIVRPGELGLDRAASTLCDNTATARFMTEGNTAANRTKLAVLLAEGARPDEAFGD
ETLDLIREQFRAFTADKITPHAHQWHMDDALIPMEVVQEMAALGVFGVCIAEKHGGLGLGKTAMCLVSEELSRGWICAGS
LGTRSEIAGELIGENGTAEQKAKFLPQIADGSILPTAVFTEPDTGSDLASVRMRGVRQADGSWQVSGAKTWITHAARADL
MTMLVRTDPGTPGYGGLSMLLAEKTRGTDADPFPDTGIDGSEIEVLGYRGMKEYALGFDGFAVAADGLLGGAEGQGFKQL
MRTFEGARIQTAARAIGVAWNAFDLGLQYALERKQFGKPLLAFPRVADKLALMVAELVLARELTYSAARHKDKGDRCDIE
AGQAKLLAARTAWSNADNALQIHGGNGYALEYPISRVLCDARILNIFEGAGEIQAQVIGRGTLKAQPSAA

Sequences:

>Translated_550_residues
MSEWIDLARQACAAARDFAEAARVVAAVAVAPEGRPDPVLVEREQRLVHGYAWIGTTVAALEATADWASRAEAAGRFVDV
DELVLKIGFGEYLHQLASGVPMSQNEIVRPGELGLDRAASTLCDNTATARFMTEGNTAANRTKLAVLLAEGARPDEAFGD
ETLDLIREQFRAFTADKITPHAHQWHMDDALIPMEVVQEMAALGVFGVCIAEKHGGLGLGKTAMCLVSEELSRGWICAGS
LGTRSEIAGELIGENGTAEQKAKFLPQIADGSILPTAVFTEPDTGSDLASVRMRGVRQADGSWQVSGAKTWITHAARADL
MTMLVRTDPGTPGYGGLSMLLAEKTRGTDADPFPDTGIDGSEIEVLGYRGMKEYALGFDGFAVAADGLLGGAEGQGFKQL
MRTFEGARIQTAARAIGVAWNAFDLGLQYALERKQFGKPLLAFPRVADKLALMVAELVLARELTYSAARHKDKGDRCDIE
AGQAKLLAARTAWSNADNALQIHGGNGYALEYPISRVLCDARILNIFEGAGEIQAQVIGRGTLKAQPSAA
>Mature_549_residues
SEWIDLARQACAAARDFAEAARVVAAVAVAPEGRPDPVLVEREQRLVHGYAWIGTTVAALEATADWASRAEAAGRFVDVD
ELVLKIGFGEYLHQLASGVPMSQNEIVRPGELGLDRAASTLCDNTATARFMTEGNTAANRTKLAVLLAEGARPDEAFGDE
TLDLIREQFRAFTADKITPHAHQWHMDDALIPMEVVQEMAALGVFGVCIAEKHGGLGLGKTAMCLVSEELSRGWICAGSL
GTRSEIAGELIGENGTAEQKAKFLPQIADGSILPTAVFTEPDTGSDLASVRMRGVRQADGSWQVSGAKTWITHAARADLM
TMLVRTDPGTPGYGGLSMLLAEKTRGTDADPFPDTGIDGSEIEVLGYRGMKEYALGFDGFAVAADGLLGGAEGQGFKQLM
RTFEGARIQTAARAIGVAWNAFDLGLQYALERKQFGKPLLAFPRVADKLALMVAELVLARELTYSAARHKDKGDRCDIEA
GQAKLLAARTAWSNADNALQIHGGNGYALEYPISRVLCDARILNIFEGAGEIQAQVIGRGTLKAQPSAA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=348, Percent_Identity=32.183908045977, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=32.6259946949602, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=32.6259946949602, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4557233, Length=393, Percent_Identity=33.587786259542, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI4501859, Length=391, Percent_Identity=30.1790281329923, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI7656849, Length=412, Percent_Identity=30.3398058252427, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI226958412, Length=382, Percent_Identity=27.7486910994764, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI4501857, Length=380, Percent_Identity=28.1578947368421, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI226958414, Length=348, Percent_Identity=29.3103448275862, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI4557235, Length=361, Percent_Identity=31.3019390581717, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI76496475, Length=361, Percent_Identity=31.3019390581717, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI4503943, Length=409, Percent_Identity=29.0953545232274, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI7669494, Length=397, Percent_Identity=28.7153652392947, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI48976061, Length=304, Percent_Identity=27.3026315789474, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI38505218, Length=340, Percent_Identity=25, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI211971008, Length=304, Percent_Identity=27.3026315789474, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1786223, Length=364, Percent_Identity=28.021978021978, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI87081958, Length=355, Percent_Identity=29.0140845070423, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI87082384, Length=267, Percent_Identity=26.2172284644195, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17534899, Length=387, Percent_Identity=34.8837209302326, Blast_Score=189, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17569725, Length=388, Percent_Identity=34.7938144329897, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=33.0708661417323, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17538396, Length=397, Percent_Identity=29.9748110831234, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71985184, Length=354, Percent_Identity=31.9209039548023, Blast_Score=161, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI17506239, Length=371, Percent_Identity=29.9191374663073, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17533517, Length=379, Percent_Identity=28.2321899736148, Blast_Score=148, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI17508101, Length=373, Percent_Identity=29.2225201072386, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17505929, Length=396, Percent_Identity=27.2727272727273, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17551932, Length=392, Percent_Identity=27.2959183673469, Blast_Score=122, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI71985192, Length=340, Percent_Identity=28.2352941176471, Blast_Score=115, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI71990804, Length=288, Percent_Identity=29.8611111111111, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=374, Percent_Identity=25.668449197861, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32563615, Length=241, Percent_Identity=29.045643153527, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982178, Length=321, Percent_Identity=25.8566978193146, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562446, Length=377, Percent_Identity=24.6684350132626, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24660351, Length=388, Percent_Identity=32.4742268041237, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI21355753, Length=398, Percent_Identity=31.9095477386935, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24646207, Length=385, Percent_Identity=30.3896103896104, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21356377, Length=391, Percent_Identity=30.690537084399, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI281363737, Length=345, Percent_Identity=30.7246376811594, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24666513, Length=409, Percent_Identity=28.6063569682152, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI19920834, Length=382, Percent_Identity=26.9633507853403, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 58673; Mature: 58542

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEWIDLARQACAAARDFAEAARVVAAVAVAPEGRPDPVLVEREQRLVHGYAWIGTTVAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
LEATADWASRAEAAGRFVDVDELVLKIGFGEYLHQLASGVPMSQNEIVRPGELGLDRAAS
HHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
TLCDNTATARFMTEGNTAANRTKLAVLLAEGARPDEAFGDETLDLIREQFRAFTADKITP
HHHCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHCCCCC
HAHQWHMDDALIPMEVVQEMAALGVFGVCIAEKHGGLGLGKTAMCLVSEELSRGWICAGS
CCCEECCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHCCCEEEECC
LGTRSEIAGELIGENGTAEQKAKFLPQIADGSILPTAVFTEPDTGSDLASVRMRGVRQAD
CCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCC
GSWQVSGAKTWITHAARADLMTMLVRTDPGTPGYGGLSMLLAEKTRGTDADPFPDTGIDG
CCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
SEIEVLGYRGMKEYALGFDGFAVAADGLLGGAEGQGFKQLMRTFEGARIQTAARAIGVAW
CCEEEEECCCCHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
NAFDLGLQYALERKQFGKPLLAFPRVADKLALMVAELVLARELTYSAARHKDKGDRCDIE
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AGQAKLLAARTAWSNADNALQIHGGNGYALEYPISRVLCDARILNIFEGAGEIQAQVIGR
CCCHHEEEEHHHCCCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEEC
GTLKAQPSAA
CCCCCCCCCC
>Mature Secondary Structure 
SEWIDLARQACAAARDFAEAARVVAAVAVAPEGRPDPVLVEREQRLVHGYAWIGTTVAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
LEATADWASRAEAAGRFVDVDELVLKIGFGEYLHQLASGVPMSQNEIVRPGELGLDRAAS
HHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
TLCDNTATARFMTEGNTAANRTKLAVLLAEGARPDEAFGDETLDLIREQFRAFTADKITP
HHHCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHCCCCC
HAHQWHMDDALIPMEVVQEMAALGVFGVCIAEKHGGLGLGKTAMCLVSEELSRGWICAGS
CCCEECCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHCCCEEEECC
LGTRSEIAGELIGENGTAEQKAKFLPQIADGSILPTAVFTEPDTGSDLASVRMRGVRQAD
CCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCC
GSWQVSGAKTWITHAARADLMTMLVRTDPGTPGYGGLSMLLAEKTRGTDADPFPDTGIDG
CCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
SEIEVLGYRGMKEYALGFDGFAVAADGLLGGAEGQGFKQLMRTFEGARIQTAARAIGVAW
CCEEEEECCCCHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
NAFDLGLQYALERKQFGKPLLAFPRVADKLALMVAELVLARELTYSAARHKDKGDRCDIE
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AGQAKLLAARTAWSNADNALQIHGGNGYALEYPISRVLCDARILNIFEGAGEIQAQVIGR
CCCHHEEEEHHHCCCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEEC
GTLKAQPSAA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]