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The map label for this gene is wecB [H]

Identifier: 85060361

GI number: 85060361

Start: 4087664

End: 4088788

Strand: Reverse

Name: wecB [H]

Synonym: SG2383

Alternate gene names: 85060361

Gene position: 4088788-4087664 (Counterclockwise)

Preceding gene: 85060362

Following gene: 85060360

Centisome position: 98.03

GC content: 58.76

Gene sequence:

>1125_bases
GTGAAAGTGTTGATCGTCTTTGGCACACGGCCGGAAGCCATCAAGATGGCGCCGCTGGTTCTGGCTTTGGCCAATGATCT
GGCCTTTGAAACCCGCGTCTGCGTGACGGCCCAGCATCGTGAGATGCTGGATCAGGTATTGCGCCTGTTCGCGATCGTGC
CTGATTACGATCTGGATATCATGCGCCCGGCACAGGGCTTGAGTGAGATAACCAGCCGTATCCTGACCGGCATGCAGCCG
GTATTGGAAGATTTCCGCCCGGATGTCGTGCTGGTGCATGGCGATACCACCACGACCTTGGCCGCCAGCCTGGCGGCGTT
TTACCAGCATATTCCCGTGGGACATGTAGAAGCGGGCTTGCGCACCGGCGATCTGCTTTCCCCGTGGCCGGAAGAGGCGA
ATCGCAAATTGACCGGCCACCTGGCCCGCTGGCATTTTGCGCCCACCGAAAATGCGCGCGCCAATTTGCTGGCGGAGGGA
CTGCCGGCGGCACGAATTGCTGTGACCGGCAATACGGTTATCGATGCGCTGTTCTGGGTGCGTGATCGTGTCATGAGCGA
CGCGGCACTGCGCGCCAGTCTGGAGCGGCGTTACGCATTTCTCGATGGCGTGCAGAAGATGATTTTGGTTACCGGCCACC
GCCGAGAGAGTTTTGGTGACGGCTTCAAGCGCATTTGCGCCGCCTTGGCGCGCATTGCGCTCGATCATCCCGACGTGCAG
GTGGTCTACCCGGTGCACCTCAATCCTAACGTCAGCGAACCGGTTAACCGTATGCTTAGCGGTATCGCCAATATAAAATT
AATTGATCCGCAGGACTATTTGCCGTTCGTGTATTTAATGGATCGCGCCACGATTATTCTGACCGATTCCGGCGGGATCC
AGGAAGAGGCGCCTTCTCTGGGAAGGCCGGTTCTGGTGATGCGTGATGCCACCGAGCGACCGGAGGCGGTGGCGGCCGGC
ACCGTACGGCTGGTAGGGACGGACGAGCAGGCGATTCACCAGGCGGTATCGCAACTGCTGAATGATTCCCAGGCGTATCA
ACGGATGAGTCGGGCACATAACCCCTACGGCGACGGCCACGCCTGTGAGCGGATTATCACGGTATTAAAAAAAGATAGCA
GGTGA

Upstream 100 bases:

>100_bases
CGACAGGCATTAAACTGTCGGAATAGACCGCTGCCATTAGCCGCGCGGCCCACCGAATTCTAAGCCGTAGCCGGCTTTGC
TCAGAATGAAGGGAACTGTT

Downstream 100 bases:

>100_bases
ATCCATGAGTTTTGACACAATTTCCGTAATTGGACTGGGGTACATCGGTCTGCCCACCGCCGCGGCGTTTGCCTCGCGCC
GCAAGCGGGTAATAGGGGTA

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MKVLIVFGTRPEAIKMAPLVLALANDLAFETRVCVTAQHREMLDQVLRLFAIVPDYDLDIMRPAQGLSEITSRILTGMQP
VLEDFRPDVVLVHGDTTTTLAASLAAFYQHIPVGHVEAGLRTGDLLSPWPEEANRKLTGHLARWHFAPTENARANLLAEG
LPAARIAVTGNTVIDALFWVRDRVMSDAALRASLERRYAFLDGVQKMILVTGHRRESFGDGFKRICAALARIALDHPDVQ
VVYPVHLNPNVSEPVNRMLSGIANIKLIDPQDYLPFVYLMDRATIILTDSGGIQEEAPSLGRPVLVMRDATERPEAVAAG
TVRLVGTDEQAIHQAVSQLLNDSQAYQRMSRAHNPYGDGHACERIITVLKKDSR

Sequences:

>Translated_374_residues
MKVLIVFGTRPEAIKMAPLVLALANDLAFETRVCVTAQHREMLDQVLRLFAIVPDYDLDIMRPAQGLSEITSRILTGMQP
VLEDFRPDVVLVHGDTTTTLAASLAAFYQHIPVGHVEAGLRTGDLLSPWPEEANRKLTGHLARWHFAPTENARANLLAEG
LPAARIAVTGNTVIDALFWVRDRVMSDAALRASLERRYAFLDGVQKMILVTGHRRESFGDGFKRICAALARIALDHPDVQ
VVYPVHLNPNVSEPVNRMLSGIANIKLIDPQDYLPFVYLMDRATIILTDSGGIQEEAPSLGRPVLVMRDATERPEAVAAG
TVRLVGTDEQAIHQAVSQLLNDSQAYQRMSRAHNPYGDGHACERIITVLKKDSR
>Mature_374_residues
MKVLIVFGTRPEAIKMAPLVLALANDLAFETRVCVTAQHREMLDQVLRLFAIVPDYDLDIMRPAQGLSEITSRILTGMQP
VLEDFRPDVVLVHGDTTTTLAASLAAFYQHIPVGHVEAGLRTGDLLSPWPEEANRKLTGHLARWHFAPTENARANLLAEG
LPAARIAVTGNTVIDALFWVRDRVMSDAALRASLERRYAFLDGVQKMILVTGHRRESFGDGFKRICAALARIALDHPDVQ
VVYPVHLNPNVSEPVNRMLSGIANIKLIDPQDYLPFVYLMDRATIILTDSGGIQEEAPSLGRPVLVMRDATERPEAVAAG
TVRLVGTDEQAIHQAVSQLLNDSQAYQRMSRAHNPYGDGHACERIITVLKKDSR

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=372, Percent_Identity=73.1182795698925, Blast_Score=548, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41327; Mature: 41327

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLIVFGTRPEAIKMAPLVLALANDLAFETRVCVTAQHREMLDQVLRLFAIVPDYDLDI
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHCCCCCCCC
MRPAQGLSEITSRILTGMQPVLEDFRPDVVLVHGDTTTTLAASLAAFYQHIPVGHVEAGL
CCHHHHHHHHHHHHHHCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHCCC
RTGDLLSPWPEEANRKLTGHLARWHFAPTENARANLLAEGLPAARIAVTGNTVIDALFWV
CCCCCCCCCCHHHCCHHHHHHHHEECCCCCCCHHHHHHCCCCCEEEEEECHHHHHHHHHH
RDRVMSDAALRASLERRYAFLDGVQKMILVTGHRRESFGDGFKRICAALARIALDHPDVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHCCCCCEE
VVYPVHLNPNVSEPVNRMLSGIANIKLIDPQDYLPFVYLMDRATIILTDSGGIQEEAPSL
EEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEECCEEEEEECCCCCCCCCCCC
GRPVLVMRDATERPEAVAAGTVRLVGTDEQAIHQAVSQLLNDSQAYQRMSRAHNPYGDGH
CCCEEEEECCCCCCCCEECCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCH
ACERIITVLKKDSR
HHHHHHHHHHCCCC
>Mature Secondary Structure
MKVLIVFGTRPEAIKMAPLVLALANDLAFETRVCVTAQHREMLDQVLRLFAIVPDYDLDI
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHCCCCCCCC
MRPAQGLSEITSRILTGMQPVLEDFRPDVVLVHGDTTTTLAASLAAFYQHIPVGHVEAGL
CCHHHHHHHHHHHHHHCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHCCC
RTGDLLSPWPEEANRKLTGHLARWHFAPTENARANLLAEGLPAARIAVTGNTVIDALFWV
CCCCCCCCCCHHHCCHHHHHHHHEECCCCCCCHHHHHHCCCCCEEEEEECHHHHHHHHHH
RDRVMSDAALRASLERRYAFLDGVQKMILVTGHRRESFGDGFKRICAALARIALDHPDVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHCCCCCEE
VVYPVHLNPNVSEPVNRMLSGIANIKLIDPQDYLPFVYLMDRATIILTDSGGIQEEAPSL
EEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEECCEEEEEECCCCCCCCCCCC
GRPVLVMRDATERPEAVAAGTVRLVGTDEQAIHQAVSQLLNDSQAYQRMSRAHNPYGDGH
CCCEEEEECCCCCCCCEECCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCH
ACERIITVLKKDSR
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]