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The map label for this gene is xerC

Identifier: 85060322

GI number: 85060322

Start: 4022608

End: 4023519

Strand: Reverse

Name: xerC

Synonym: SG2344

Alternate gene names: 85060322

Gene position: 4023519-4022608 (Counterclockwise)

Preceding gene: 85060323

Following gene: 85060321

Centisome position: 96.46

GC content: 60.64

Gene sequence:

>912_bases
ATGACCGGCACAGGCTCTCCGCTGCAGCTGCAGGTAGACGCTTTCCTGCATTATCTGCGTGTGGAGCTGCAACTGAGCGC
CAAAACGCGGGAAAGCTATCAGCGGCAGCTGTATACCGTTATCGTCCTGATCGATGAAATGGGGCTGACGGAATGGAGAC
AGCTGGAGGTGAGCCAGGTGCGTGCGCTGGCCGCGCGCAGCAAGCGCCAGGGGCTACAGTCCGCCAGTTTGGCGCTGCGG
CTCTCTGCGCTACGCAGCTTTCTCGACTGGCTGGTGAGCACCGACGCGCTGGGCGCAAACCCGGCACGCGGCGTTTCCGC
GCCACGCCACGGACGGCATTTGCCAAAAAACATGGATGTGGATGAAGTTGACCACCTGCTGGATATCGATACCCGCGACC
CGCTGGCCCTGCGCGACCGCGCGATGCTTGAAGTGATGTACGGCGCGGGCCTGCGTTTGGCGGAGCTGGTCGGCCTGAAT
TGCGCGGATGTGGATCTCGGCGGCGGCGAAGTGCGGGTGGTGGGTAAAGGCAACAAAGAGCGTAAATTGCCCATCGGCGC
CACCGCCGTCACCTGGCTGACGCGCTGGTTAACGCTACGTGACCGTTACGCGCCCAAGGATGATGCGGTGTTTATCGCCA
ACAGCGGACGTCGCATTTCCGCGCGCAACGTACAAAAACGTTTCGCCGAATGGGGTGTGAAGCAAGGGGTAAACAGCCAT
ATCCATCCCCATAAGCTGCGCCACTCCTTCGCCACCCATATGCTGGAGTCAAGCGGCAACTTGCGCGCGGTACAGGAGCT
GCTTGGCCACGCCAACCTCAGTACCACCCAGATTTACACTCACCTCGATTTTCAGCATTTGGCATCGGTGTATGATGCCG
CGCACCCACGAGCCAAACGGGAAAAAACCTGA

Upstream 100 bases:

>100_bases
GCCGCGACAGCCAGCATTTCCAGGACGGGATGGGCACGGTGTTATTACAGCAGTTGGCCACGCTGTTACCGGGGCTGCTG
GAACGTTGGGTCAGCCGGGC

Downstream 100 bases:

>100_bases
TGCATTTCTATCGTCCTTTGCGACCGCTGCGCGCGTTAACCTTTGATCTCGATGATACCCTGTACGATAACCGGCCGGTG
ATTGCCCGCACCGAATATGA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MTGTGSPLQLQVDAFLHYLRVELQLSAKTRESYQRQLYTVIVLIDEMGLTEWRQLEVSQVRALAARSKRQGLQSASLALR
LSALRSFLDWLVSTDALGANPARGVSAPRHGRHLPKNMDVDEVDHLLDIDTRDPLALRDRAMLEVMYGAGLRLAELVGLN
CADVDLGGGEVRVVGKGNKERKLPIGATAVTWLTRWLTLRDRYAPKDDAVFIANSGRRISARNVQKRFAEWGVKQGVNSH
IHPHKLRHSFATHMLESSGNLRAVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKREKT

Sequences:

>Translated_303_residues
MTGTGSPLQLQVDAFLHYLRVELQLSAKTRESYQRQLYTVIVLIDEMGLTEWRQLEVSQVRALAARSKRQGLQSASLALR
LSALRSFLDWLVSTDALGANPARGVSAPRHGRHLPKNMDVDEVDHLLDIDTRDPLALRDRAMLEVMYGAGLRLAELVGLN
CADVDLGGGEVRVVGKGNKERKLPIGATAVTWLTRWLTLRDRYAPKDDAVFIANSGRRISARNVQKRFAEWGVKQGVNSH
IHPHKLRHSFATHMLESSGNLRAVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKREKT
>Mature_302_residues
TGTGSPLQLQVDAFLHYLRVELQLSAKTRESYQRQLYTVIVLIDEMGLTEWRQLEVSQVRALAARSKRQGLQSASLALRL
SALRSFLDWLVSTDALGANPARGVSAPRHGRHLPKNMDVDEVDHLLDIDTRDPLALRDRAMLEVMYGAGLRLAELVGLNC
ADVDLGGGEVRVVGKGNKERKLPIGATAVTWLTRWLTLRDRYAPKDDAVFIANSGRRISARNVQKRFAEWGVKQGVNSHI
HPHKLRHSFATHMLESSGNLRAVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKREKT

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerD binding sites by a short central region, forming

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=297, Percent_Identity=69.023569023569, Blast_Score=421, Evalue=1e-119,
Organism=Escherichia coli, GI1789261, Length=296, Percent_Identity=37.5, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1790768, Length=181, Percent_Identity=27.0718232044199, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790767, Length=182, Percent_Identity=26.3736263736264, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33901; Mature: 33770

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGTGSPLQLQVDAFLHYLRVELQLSAKTRESYQRQLYTVIVLIDEMGLTEWRQLEVSQV
CCCCCCCEEEEHHHHHHHHHHHEEECHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHH
RALAARSKRQGLQSASLALRLSALRSFLDWLVSTDALGANPARGVSAPRHGRHLPKNMDV
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCH
DEVDHLLDIDTRDPLALRDRAMLEVMYGAGLRLAELVGLNCADVDLGGGEVRVVGKGNKE
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEECCCCEEEEEECCCCC
RKLPIGATAVTWLTRWLTLRDRYAPKDDAVFIANSGRRISARNVQKRFAEWGVKQGVNSH
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHCCCCC
IHPHKLRHSFATHMLESSGNLRAVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKR
CCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHEEECCCHHHHHHHHHHCCCCCCC
EKT
CCC
>Mature Secondary Structure 
TGTGSPLQLQVDAFLHYLRVELQLSAKTRESYQRQLYTVIVLIDEMGLTEWRQLEVSQV
CCCCCCEEEEHHHHHHHHHHHEEECHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHH
RALAARSKRQGLQSASLALRLSALRSFLDWLVSTDALGANPARGVSAPRHGRHLPKNMDV
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCH
DEVDHLLDIDTRDPLALRDRAMLEVMYGAGLRLAELVGLNCADVDLGGGEVRVVGKGNKE
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEECCCCEEEEEECCCCC
RKLPIGATAVTWLTRWLTLRDRYAPKDDAVFIANSGRRISARNVQKRFAEWGVKQGVNSH
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHCCCCC
IHPHKLRHSFATHMLESSGNLRAVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKR
CCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHEEECCCHHHHHHHHHHCCCCCCC
EKT
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9555916 [H]