Click here to switch to the map view.

The map label for this gene is glpR [H]

Identifier: 85060304

GI number: 85060304

Start: 3995654

End: 3996412

Strand: Reverse

Name: glpR [H]

Synonym: SG2326

Alternate gene names: 85060304

Gene position: 3996412-3995654 (Counterclockwise)

Preceding gene: 85060305

Following gene: 85060302

Centisome position: 95.81

GC content: 57.31

Gene sequence:

>759_bases
GTGAAGCAAACGCAGCGGCATGATGCCATCATCGATCTGGTTCGCCAGCAGGGCTACGTCAGCACCGAGGAACTGGTAGA
TCACTTTGCCGTCAGTCCGCAGACGATACGGCGCGATCTCAACGATTTGGCCGAGCAGAACAAGATCCAGCGTCATCACG
GCGGTGCGGCGCTGCCGTCGAGTTCGGTTAACGCCGCCTATCATGACCGCAAAGTGATGTGGTCGGCGGAAAAGGCGCGC
ATTGCGGCGCGTGTCGCGAGCCAGATCCCCGACGGGGCAACGCTATTTATCGATATCGGCACTACGCCGGAGGCGGTGGC
GCATGCGCTGTTGGGTCATAAAAACCTGCGGGTAGTGACCAATAATCTCAACGTGGCGACGCTGCTTACCGCCAAGGAGG
ATTTCCGCCTGATCCTGGCCGGGGGGGAAGTGCGGACGCGCGACGGCGGTATTATCGGCGAGGCCACTCTCGATTTTATT
TCTCAATTCCGGCTTGATTACGGCATTCTCGGCATCAGCAGTATCGATTTGGACGGCTCACTGCTGGAGTTCGATTATCA
CGAAGTACGCACCAAACGGGCGATTATCGACAATTCCCGCTGTGTGATGCTGGTGACAGACCATTCCAAATTCGGCCGCA
GCGCCATGGTGAACCTCGGCAAAATGGATCTGGTGGACTATCTGTTTACCGACCAACTGCCACCCCCGGGCGTGATGACG
CTTATCGAACATTCCGATGTCAAACTGGAGCTGTGCTGA

Upstream 100 bases:

>100_bases
GGCGGGTCTGGTCACGGGCCTGCTAATGGCATTCTGGCAAACGCGGCGGGGTCAGAGTCACGGCTATCAGCGCTGATCGG
CCGGCAGCAGAGGAATCAAC

Downstream 100 bases:

>100_bases
GCGCAAAAGCGACAGCATAAAAATCCTCGCCGGCGCACTCTTTTTCAACGGCGTTGTCTATTCTTTGATCATCACGACGT
TAGCCAGACTCTTCCGCTAT

Product: DNA-binding transcriptional repressor GlpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKQTQRHDAIIDLVRQQGYVSTEELVDHFAVSPQTIRRDLNDLAEQNKIQRHHGGAALPSSSVNAAYHDRKVMWSAEKAR
IAARVASQIPDGATLFIDIGTTPEAVAHALLGHKNLRVVTNNLNVATLLTAKEDFRLILAGGEVRTRDGGIIGEATLDFI
SQFRLDYGILGISSIDLDGSLLEFDYHEVRTKRAIIDNSRCVMLVTDHSKFGRSAMVNLGKMDLVDYLFTDQLPPPGVMT
LIEHSDVKLELC

Sequences:

>Translated_252_residues
MKQTQRHDAIIDLVRQQGYVSTEELVDHFAVSPQTIRRDLNDLAEQNKIQRHHGGAALPSSSVNAAYHDRKVMWSAEKAR
IAARVASQIPDGATLFIDIGTTPEAVAHALLGHKNLRVVTNNLNVATLLTAKEDFRLILAGGEVRTRDGGIIGEATLDFI
SQFRLDYGILGISSIDLDGSLLEFDYHEVRTKRAIIDNSRCVMLVTDHSKFGRSAMVNLGKMDLVDYLFTDQLPPPGVMT
LIEHSDVKLELC
>Mature_252_residues
MKQTQRHDAIIDLVRQQGYVSTEELVDHFAVSPQTIRRDLNDLAEQNKIQRHHGGAALPSSSVNAAYHDRKVMWSAEKAR
IAARVASQIPDGATLFIDIGTTPEAVAHALLGHKNLRVVTNNLNVATLLTAKEDFRLILAGGEVRTRDGGIIGEATLDFI
SQFRLDYGILGISSIDLDGSLLEFDYHEVRTKRAIIDNSRCVMLVTDHSKFGRSAMVNLGKMDLVDYLFTDQLPPPGVMT
LIEHSDVKLELC

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=252, Percent_Identity=75.7936507936508, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI87082344, Length=246, Percent_Identity=42.6829268292683, Blast_Score=215, Evalue=2e-57,
Organism=Escherichia coli, GI1789519, Length=235, Percent_Identity=29.3617021276596, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1789059, Length=249, Percent_Identity=29.3172690763052, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI226510968, Length=246, Percent_Identity=30.4878048780488, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789170, Length=230, Percent_Identity=29.1304347826087, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788069, Length=251, Percent_Identity=25.8964143426295, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790635, Length=261, Percent_Identity=23.7547892720307, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790753, Length=253, Percent_Identity=24.1106719367589, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787540, Length=248, Percent_Identity=26.2096774193548, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787063, Length=255, Percent_Identity=25.8823529411765, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27899; Mature: 27899

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTQRHDAIIDLVRQQGYVSTEELVDHFAVSPQTIRRDLNDLAEQNKIQRHHGGAALPS
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SSVNAAYHDRKVMWSAEKARIAARVASQIPDGATLFIDIGTTPEAVAHALLGHKNLRVVT
CCCCCHHCCCEEEECHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEE
NNLNVATLLTAKEDFRLILAGGEVRTRDGGIIGEATLDFISQFRLDYGILGISSIDLDGS
CCCCEEEEEEECCCCEEEEECCEEEECCCCEEHHHHHHHHHHHHHHHCEEEEEEECCCCC
LLEFDYHEVRTKRAIIDNSRCVMLVTDHSKFGRSAMVNLGKMDLVDYLFTDQLPPPGVMT
EEECHHHHHHHHHHEECCCCEEEEEECCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCEE
LIEHSDVKLELC
EEECCCEEEEEC
>Mature Secondary Structure
MKQTQRHDAIIDLVRQQGYVSTEELVDHFAVSPQTIRRDLNDLAEQNKIQRHHGGAALPS
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SSVNAAYHDRKVMWSAEKARIAARVASQIPDGATLFIDIGTTPEAVAHALLGHKNLRVVT
CCCCCHHCCCEEEECHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEE
NNLNVATLLTAKEDFRLILAGGEVRTRDGGIIGEATLDFISQFRLDYGILGISSIDLDGS
CCCCEEEEEEECCCCEEEEECCEEEECCCCEEHHHHHHHHHHHHHHHCEEEEEEECCCCC
LLEFDYHEVRTKRAIIDNSRCVMLVTDHSKFGRSAMVNLGKMDLVDYLFTDQLPPPGVMT
EEECHHHHHHHHHHEECCCCEEEEEECCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCEE
LIEHSDVKLELC
EEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]