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The map label for this gene is aroB

Identifier: 85060286

GI number: 85060286

Start: 3966804

End: 3967889

Strand: Reverse

Name: aroB

Synonym: SG2308

Alternate gene names: 85060286

Gene position: 3967889-3966804 (Counterclockwise)

Preceding gene: 85060287

Following gene: 85060285

Centisome position: 95.13

GC content: 59.3

Gene sequence:

>1086_bases
ATGGAGAGGATTACCGTTACATTAGGGGAGCGCAGCTACCCGATTACCATTGCCGCCGGATTATTCAATGATCCGGCGTC
TTTCTGGCCGTTAACGCGCGGCGATAGCGCCATGCTGGTGACGAACGACCGCCTCGCTCCCCTGTATCTGGAATCCCTGT
GCGAGCGGCTGACCCAGGCCGGCGTCAAGGTCGATCGGGTCGTATTGCCTGACGGTGAACAGAATAAATCGTTGACCGTG
CTGGATCAGGTTTTCACCGCGCTGCTGGCTAAATCCCATGGTCGCGATACTACCCTTATCGCGCTCGGTGGCGGCGTCAT
CGGCGATCTGGCCGGTTTCGCCGCCGCCAGTTATCAACGCGGTGTGCGTTTTATCCAGGCACCTACCACGCTACTCTCAC
AGGTTGACTCCTCAGTTGGCGGCAAAACCGCCGTCAATCATTCTCTCGGCAAGAACATGATCGGCGCCTTCTATCAACCT
GCGTCAGTGGTCATTGACTTGGACTGTCTCAACACGCTTCCGCGGCGGGAACTCTCCTCGGGCCTGGCGGAAGTTATCAA
GTACGGTATTATTCTTGATGCGGCTTTTTTTGCCTGGCTTGAAGACAATCTCGAAGCGCTGTTGGCGCTAGAGCCGCAAG
CGCTGGCCTATTGCATCCGTCGCTGCTGCGAGCTGAAAGCCGACGTAGTGGCTGCCGATGAACGCGAGCAGGGCCAGCGT
GCTCTGCTGAATCTTGGCCACACCTACGGCCATGCCATCGAAACCCACATGGGTTATGGCAACTGGCTGCATGGCGAAGC
CGTGGCCGCCGGCATGATGATGGCGGTGCGCGCCGCGCGTCGGCTCGGTCAATTCAGCGATGCTGATGCTGAACGGGTGA
GTGCGCTGCTGCAGCGCGCCGGCCTGACGATGAGCGGTCCGGCGGAAATGGCGCCGGAAGATTACCTGCCGCATATGATG
CGTGATAAAAAAGTCATCGCCGGCCGGCTGCGTCTGGTCCTGCCGGTGACGCTGGGCAATGCGGAAGTGCGTACCGGCGT
GGCTGATGATATGGTGGTGGCGTCTATTAAGGATTGCCAGGCCTGA

Upstream 100 bases:

>100_bases
GATGAACAAAGCGCCAAGGTTGTTGCTAACCAAATTATCAATATGCTGGAAAGCAGCTAATCTAAATTAACGAGATGCCG
AAAAGGTCACTGAGCGTCCC

Downstream 100 bases:

>100_bases
GCCGGCCGGCCGCGCGCCAGGGCGCGTCGGTGAAGCCCGGTTTAATGTGATAAACCCTTCCCGCGCTCCGGCGCTGGAAA
AACCCCTCTCATGTCGGAGA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MERITVTLGERSYPITIAAGLFNDPASFWPLTRGDSAMLVTNDRLAPLYLESLCERLTQAGVKVDRVVLPDGEQNKSLTV
LDQVFTALLAKSHGRDTTLIALGGGVIGDLAGFAAASYQRGVRFIQAPTTLLSQVDSSVGGKTAVNHSLGKNMIGAFYQP
ASVVIDLDCLNTLPRRELSSGLAEVIKYGIILDAAFFAWLEDNLEALLALEPQALAYCIRRCCELKADVVAADEREQGQR
ALLNLGHTYGHAIETHMGYGNWLHGEAVAAGMMMAVRAARRLGQFSDADAERVSALLQRAGLTMSGPAEMAPEDYLPHMM
RDKKVIAGRLRLVLPVTLGNAEVRTGVADDMVVASIKDCQA

Sequences:

>Translated_361_residues
MERITVTLGERSYPITIAAGLFNDPASFWPLTRGDSAMLVTNDRLAPLYLESLCERLTQAGVKVDRVVLPDGEQNKSLTV
LDQVFTALLAKSHGRDTTLIALGGGVIGDLAGFAAASYQRGVRFIQAPTTLLSQVDSSVGGKTAVNHSLGKNMIGAFYQP
ASVVIDLDCLNTLPRRELSSGLAEVIKYGIILDAAFFAWLEDNLEALLALEPQALAYCIRRCCELKADVVAADEREQGQR
ALLNLGHTYGHAIETHMGYGNWLHGEAVAAGMMMAVRAARRLGQFSDADAERVSALLQRAGLTMSGPAEMAPEDYLPHMM
RDKKVIAGRLRLVLPVTLGNAEVRTGVADDMVVASIKDCQA
>Mature_361_residues
MERITVTLGERSYPITIAAGLFNDPASFWPLTRGDSAMLVTNDRLAPLYLESLCERLTQAGVKVDRVVLPDGEQNKSLTV
LDQVFTALLAKSHGRDTTLIALGGGVIGDLAGFAAASYQRGVRFIQAPTTLLSQVDSSVGGKTAVNHSLGKNMIGAFYQP
ASVVIDLDCLNTLPRRELSSGLAEVIKYGIILDAAFFAWLEDNLEALLALEPQALAYCIRRCCELKADVVAADEREQGQR
ALLNLGHTYGHAIETHMGYGNWLHGEAVAAGMMMAVRAARRLGQFSDADAERVSALLQRAGLTMSGPAEMAPEDYLPHMM
RDKKVIAGRLRLVLPVTLGNAEVRTGVADDMVVASIKDCQA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=361, Percent_Identity=74.792243767313, Blast_Score=551, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6320332, Length=373, Percent_Identity=35.3887399463807, Blast_Score=182, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_SODGM (Q2NQJ2)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455988.1
- ProteinModelPortal:   Q2NQJ2
- SMR:   Q2NQJ2
- STRING:   Q2NQJ2
- GeneID:   3866314
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG2308
- NMPDR:   fig|343509.6.peg.5017
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- PhylomeDB:   Q2NQJ2
- ProtClustDB:   PRK00002
- BioCyc:   SGLO343509:SG2308-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 38884; Mature: 38884

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERITVTLGERSYPITIAAGLFNDPASFWPLTRGDSAMLVTNDRLAPLYLESLCERLTQA
CCEEEEEECCCCCCEEEEECCCCCCHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHC
GVKVDRVVLPDGEQNKSLTVLDQVFTALLAKSHGRDTTLIALGGGVIGDLAGFAAASYQR
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHH
GVRFIQAPTTLLSQVDSSVGGKTAVNHSLGKNMIGAFYQPASVVIDLDCLNTLPRRELSS
CCEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCHHHHHH
GLAEVIKYGIILDAAFFAWLEDNLEALLALEPQALAYCIRRCCELKADVVAADEREQGQR
HHHHHHHHHHHHHHHHHHHHHHCHHHHEEECHHHHHHHHHHHHHHHHHHEECCCHHHHHH
ALLNLGHTYGHAIETHMGYGNWLHGEAVAAGMMMAVRAARRLGQFSDADAERVSALLQRA
HHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
GLTMSGPAEMAPEDYLPHMMRDKKVIAGRLRLVLPVTLGNAEVRTGVADDMVVASIKDCQ
CCCCCCCHHCCCHHHHHHHHHCCHHHHCEEEEEEEEEECCCHHHCCCCHHHHHHHHHHCC
A
C
>Mature Secondary Structure
MERITVTLGERSYPITIAAGLFNDPASFWPLTRGDSAMLVTNDRLAPLYLESLCERLTQA
CCEEEEEECCCCCCEEEEECCCCCCHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHC
GVKVDRVVLPDGEQNKSLTVLDQVFTALLAKSHGRDTTLIALGGGVIGDLAGFAAASYQR
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHH
GVRFIQAPTTLLSQVDSSVGGKTAVNHSLGKNMIGAFYQPASVVIDLDCLNTLPRRELSS
CCEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCHHHHHH
GLAEVIKYGIILDAAFFAWLEDNLEALLALEPQALAYCIRRCCELKADVVAADEREQGQR
HHHHHHHHHHHHHHHHHHHHHHCHHHHEEECHHHHHHHHHHHHHHHHHHEECCCHHHHHH
ALLNLGHTYGHAIETHMGYGNWLHGEAVAAGMMMAVRAARRLGQFSDADAERVSALLQRA
HHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
GLTMSGPAEMAPEDYLPHMMRDKKVIAGRLRLVLPVTLGNAEVRTGVADDMVVASIKDCQ
CCCCCCCHHCCCHHHHHHHHHCCHHHHCEEEEEEEEEECCCHHHCCCCHHHHHHHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA