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The map label for this gene is gpsA

Identifier: 85060162

GI number: 85060162

Start: 3800841

End: 3801857

Strand: Reverse

Name: gpsA

Synonym: SG2184

Alternate gene names: 85060162

Gene position: 3801857-3800841 (Counterclockwise)

Preceding gene: 85060163

Following gene: 85060161

Centisome position: 91.15

GC content: 62.14

Gene sequence:

>1017_bases
ATGCCCGGCGATGCTTCAATGATTGTTATCGGTGCCGGCTCGTACGGTACGGCCCTGGCTATCACCCTAGCGCGTAACGG
TCATGAGGTGTTGCTGTGGGGGCACGATCCGGCCCATATTCAGGCGTTGGAGGCGGTACGCTGCAATCAGGCTTTTTTGC
CCGATGTGCCGTTTCCGCCGACGCTGCGCCTGGAAGCATCGCTGCCGACGGCGCTGGCCGCCAGCCGCGATGTGCTGATT
GTGGTGCCAAGCCACGTATTCGGATCCGTGCTTACCGAGCTCAAACCGCATTTGCGCCAAGATGCCCGCATTGTCTGGGC
CACCAAGGGATTGGAGGCGGAAACCGGCCGGCTGTTGCAGGAGGTGGCGCGGGAGGTGCTGGGCGACCAGATACCGCTGG
CGGTCTTGTCGGGGCCTACGTTCGCGCGCGAGCTGGCGGCAGGGCTGCCTACCGCCATTGCGCTGGCGGCCACTGACGCC
ACGTTTAGTGCCGATTTACAGCGGCTGTTACACTGCGGTAAAAGTTTCCGGGTTTACAGTAATCCCGATCTTATCGGCGT
CCAGTTGGGTGGCGCGGTGAAGAACGTGATCGCCATCGGCGCCGGCATTTCTGACGGCATCGGTTTTGGCGCCAACGCGC
GCACCGCATTAATTACCCGCGGTCTGGCCGAAATGTCGCGCCTGGGCGCGGCGATGGGCGCAGAGCCCGGCACCTTTATG
GGCATGGCGGGATTGGGGGATCTGGTGCTTACCTGTACCGACAATCAGTCGCGTAATCGCCGCTTCGGCCTGCTGCTGGG
GCAGGGCGTCGGCTTCGAAGCGGTGCAGGAAACGATCGGACAGGTGGTGGAGGGTTACCGCAATACCAAGGAAGTATTAG
CGCTGGCCGGCCGCTATGGGGTGGAGATGCCCATCACCGAGCAGATCTATCAGGTGCTTTACCAAAACAAAAATGCTCAC
CAGGCGGCGCTGACGCTGCTTGGTCGTGCGCAGAAAGATGAAAGGGCCGGCGGCTGA

Upstream 100 bases:

>100_bases
AATTGAATCTGGCGCCGGTCAATTTTGACGCGCTGTTCATGAATTACCTGCAGCAGCAGGCCGACGGCGCAGGCAGCCAG
CCGGCTCAGGAAGCCTGATC

Downstream 100 bases:

>100_bases
GGCCGGTCACCCAGCAACAGAGCAAAAGGCGGGCGGTATGTCGACAGAAGAATTGGAACTTGTATGGAACAACATTAAAA
CTGAAGCGCGATTGCTGGCC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MPGDASMIVIGAGSYGTALAITLARNGHEVLLWGHDPAHIQALEAVRCNQAFLPDVPFPPTLRLEASLPTALAASRDVLI
VVPSHVFGSVLTELKPHLRQDARIVWATKGLEAETGRLLQEVAREVLGDQIPLAVLSGPTFARELAAGLPTAIALAATDA
TFSADLQRLLHCGKSFRVYSNPDLIGVQLGGAVKNVIAIGAGISDGIGFGANARTALITRGLAEMSRLGAAMGAEPGTFM
GMAGLGDLVLTCTDNQSRNRRFGLLLGQGVGFEAVQETIGQVVEGYRNTKEVLALAGRYGVEMPITEQIYQVLYQNKNAH
QAALTLLGRAQKDERAGG

Sequences:

>Translated_338_residues
MPGDASMIVIGAGSYGTALAITLARNGHEVLLWGHDPAHIQALEAVRCNQAFLPDVPFPPTLRLEASLPTALAASRDVLI
VVPSHVFGSVLTELKPHLRQDARIVWATKGLEAETGRLLQEVAREVLGDQIPLAVLSGPTFARELAAGLPTAIALAATDA
TFSADLQRLLHCGKSFRVYSNPDLIGVQLGGAVKNVIAIGAGISDGIGFGANARTALITRGLAEMSRLGAAMGAEPGTFM
GMAGLGDLVLTCTDNQSRNRRFGLLLGQGVGFEAVQETIGQVVEGYRNTKEVLALAGRYGVEMPITEQIYQVLYQNKNAH
QAALTLLGRAQKDERAGG
>Mature_337_residues
PGDASMIVIGAGSYGTALAITLARNGHEVLLWGHDPAHIQALEAVRCNQAFLPDVPFPPTLRLEASLPTALAASRDVLIV
VPSHVFGSVLTELKPHLRQDARIVWATKGLEAETGRLLQEVAREVLGDQIPLAVLSGPTFARELAAGLPTAIALAATDAT
FSADLQRLLHCGKSFRVYSNPDLIGVQLGGAVKNVIAIGAGISDGIGFGANARTALITRGLAEMSRLGAAMGAEPGTFMG
MAGLGDLVLTCTDNQSRNRRFGLLLGQGVGFEAVQETIGQVVEGYRNTKEVLALAGRYGVEMPITEQIYQVLYQNKNAHQ
AALTLLGRAQKDERAGG

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=337, Percent_Identity=27.893175074184, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI24307999, Length=334, Percent_Identity=24.5508982035928, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1790037, Length=333, Percent_Identity=81.981981981982, Blast_Score=563, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI17507425, Length=277, Percent_Identity=25.9927797833935, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32564399, Length=328, Percent_Identity=25.3048780487805, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193210136, Length=340, Percent_Identity=24.1176470588235, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32564403, Length=337, Percent_Identity=24.3323442136499, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193210134, Length=204, Percent_Identity=28.921568627451, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320181, Length=347, Percent_Identity=27.6657060518732, Blast_Score=96, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6324513, Length=342, Percent_Identity=25.1461988304094, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17136202, Length=339, Percent_Identity=26.8436578171091, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17136204, Length=339, Percent_Identity=26.8436578171091, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17136200, Length=339, Percent_Identity=26.8436578171091, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI22026922, Length=277, Percent_Identity=25.2707581227437, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281362270, Length=243, Percent_Identity=29.6296296296296, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45551945, Length=243, Percent_Identity=29.6296296296296, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24648969, Length=184, Percent_Identity=31.5217391304348, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_SODGM (Q2NQW6)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455864.1
- ProteinModelPortal:   Q2NQW6
- SMR:   Q2NQW6
- STRING:   Q2NQW6
- GeneID:   3866992
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG2184
- NMPDR:   fig|343509.6.peg.4811
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- PhylomeDB:   Q2NQW6
- ProtClustDB:   PRK00094
- BioCyc:   SGLO343509:SG2184-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 35591; Mature: 35460

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 194-194 BINDING 109-109 BINDING 109-109 BINDING 142-142 BINDING 258-258 BINDING 284-284

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGDASMIVIGAGSYGTALAITLARNGHEVLLWGHDPAHIQALEAVRCNQAFLPDVPFPP
CCCCCCEEEEECCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC
TLRLEASLPTALAASRDVLIVVPSHVFGSVLTELKPHLRQDARIVWATKGLEAETGRLLQ
CEEEECCCCHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHH
EVAREVLGDQIPLAVLSGPTFARELAAGLPTAIALAATDATFSADLQRLLHCGKSFRVYS
HHHHHHCCCCCCEEEECCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEC
NPDLIGVQLGGAVKNVIAIGAGISDGIGFGANARTALITRGLAEMSRLGAAMGAEPGTFM
CCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
GMAGLGDLVLTCTDNQSRNRRFGLLLGQGVGFEAVQETIGQVVEGYRNTKEVLALAGRYG
ECCCCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
VEMPITEQIYQVLYQNKNAHQAALTLLGRAQKDERAGG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PGDASMIVIGAGSYGTALAITLARNGHEVLLWGHDPAHIQALEAVRCNQAFLPDVPFPP
CCCCCEEEEECCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC
TLRLEASLPTALAASRDVLIVVPSHVFGSVLTELKPHLRQDARIVWATKGLEAETGRLLQ
CEEEECCCCHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHH
EVAREVLGDQIPLAVLSGPTFARELAAGLPTAIALAATDATFSADLQRLLHCGKSFRVYS
HHHHHHCCCCCCEEEECCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEC
NPDLIGVQLGGAVKNVIAIGAGISDGIGFGANARTALITRGLAEMSRLGAAMGAEPGTFM
CCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
GMAGLGDLVLTCTDNQSRNRRFGLLLGQGVGFEAVQETIGQVVEGYRNTKEVLALAGRYG
ECCCCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
VEMPITEQIYQVLYQNKNAHQAALTLLGRAQKDERAGG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA