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The map label for this gene is oxyR [H]

Identifier: 85060136

GI number: 85060136

Start: 3759401

End: 3760318

Strand: Reverse

Name: oxyR [H]

Synonym: SG2158

Alternate gene names: 85060136

Gene position: 3760318-3759401 (Counterclockwise)

Preceding gene: 85060137

Following gene: 85060134

Centisome position: 90.15

GC content: 58.06

Gene sequence:

>918_bases
ATGAACATTCGCGATCTAGAATATTTGGTGGCTCTGGCCGAGCATCGTCATTTTCGACGCGCCGCCGACTCCTGCCACGT
CAGTCAGCCCACTCTCAGCGGACAGGTGCGCAAGCTGGAAGATGAATTGGGCGTGATGCTGTTGGAACGAACTAGCCGTA
AAGTGCTGTTCACCCAAGCCGGCCTGCTGCTGGTGGATCAGGCGCGTACGGTGCTGCGGGAAGTAAAAGTTCTGCGCGAG
ATGGCCAGCCAGCAGGGAGAATCCATGTCGGGGCCGCTGCATATCGGCCTTATCCCTACCGTGGGGCCGTATCTGCTGTC
GCATATTGTTCCGATGCTGCACCAGGCCTTTCCCAAGCTGGAAATGTATTTACATGAGTCCCAAACCAGCCAATTGCTAC
AGCAGCTCGACAGCGGCAGACTGGACTGCGTCATTTTGGCGCTGGTAAAAGAGTCGGAAGCGTTTATTGAAGTGCCTTTG
TTTGACGAAACGATGCAGTTGGCGATTTATGCCGATCATCCCTGGGCGGATCGCGATCGGGTGCCGATGTCCGATCTGGC
CGGCGAGCGGCTACTCATGCTTGAGGATGGTCACTGTTTGCGCGATCAGGCGATGGGCTTTTGCTTCCAGGCCGGTGCCG
ACGAGGACACCCATTTCCGCGCCACCAGCCTGGAAACCCTGCGCAATATGGTGGCGGCGGGCAGCGGCATTACCCTGCTG
CCTTCCCTGGCGGTACCGCGGGAGCGCAAGCGGGATGGTGTTTGCTATCTCCCCTGTTACAGACCGGAACCGAAACGTAC
CATTGCGCTGGTGTATCGCCCCGGTTCACCGCTGCGTGCCCGCTATGAGCAACTGGCGGACTGTATCCGCAGTCATATGC
AAGCCTACATGGGCACCGGCTTAAAACAGGCGGTTTAA

Upstream 100 bases:

>100_bases
TCTGTAGCGGTAATTATTATTGATTTTAGTTATTGATAGGGTTAATCGTTGATTGCTATTCTATCTATCGACGCGGACTA
TCGCGTCGATGGAGGAATTC

Downstream 100 bases:

>100_bases
GCCGTTAAGCGCCGCCACCCGGTAGGCTTCCGCCATGGTGGGATAATTGAAGGTCGTATTGACGAAATATTCGATGGTAT
TACCTTCCCCCTTCTGCTCC

Product: DNA-binding transcriptional regulator OxyR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQVRKLEDELGVMLLERTSRKVLFTQAGLLLVDQARTVLREVKVLRE
MASQQGESMSGPLHIGLIPTVGPYLLSHIVPMLHQAFPKLEMYLHESQTSQLLQQLDSGRLDCVILALVKESEAFIEVPL
FDETMQLAIYADHPWADRDRVPMSDLAGERLLMLEDGHCLRDQAMGFCFQAGADEDTHFRATSLETLRNMVAAGSGITLL
PSLAVPRERKRDGVCYLPCYRPEPKRTIALVYRPGSPLRARYEQLADCIRSHMQAYMGTGLKQAV

Sequences:

>Translated_305_residues
MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQVRKLEDELGVMLLERTSRKVLFTQAGLLLVDQARTVLREVKVLRE
MASQQGESMSGPLHIGLIPTVGPYLLSHIVPMLHQAFPKLEMYLHESQTSQLLQQLDSGRLDCVILALVKESEAFIEVPL
FDETMQLAIYADHPWADRDRVPMSDLAGERLLMLEDGHCLRDQAMGFCFQAGADEDTHFRATSLETLRNMVAAGSGITLL
PSLAVPRERKRDGVCYLPCYRPEPKRTIALVYRPGSPLRARYEQLADCIRSHMQAYMGTGLKQAV
>Mature_305_residues
MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQVRKLEDELGVMLLERTSRKVLFTQAGLLLVDQARTVLREVKVLRE
MASQQGESMSGPLHIGLIPTVGPYLLSHIVPMLHQAFPKLEMYLHESQTSQLLQQLDSGRLDCVILALVKESEAFIEVPL
FDETMQLAIYADHPWADRDRVPMSDLAGERLLMLEDGHCLRDQAMGFCFQAGADEDTHFRATSLETLRNMVAAGSGITLL
PSLAVPRERKRDGVCYLPCYRPEPKRTIALVYRPGSPLRARYEQLADCIRSHMQAYMGTGLKQAV

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=305, Percent_Identity=87.2131147540984, Blast_Score=550, Evalue=1e-158,
Organism=Escherichia coli, GI157672245, Length=273, Percent_Identity=29.3040293040293, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787530, Length=251, Percent_Identity=25.4980079681275, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787879, Length=248, Percent_Identity=29.8387096774194, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI145693105, Length=291, Percent_Identity=26.1168384879725, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1788887, Length=251, Percent_Identity=30.2788844621514, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788748, Length=302, Percent_Identity=26.4900662251656, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790208, Length=250, Percent_Identity=29.2, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788297, Length=256, Percent_Identity=29.296875, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI2367136, Length=243, Percent_Identity=26.3374485596708, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790262, Length=245, Percent_Identity=27.7551020408163, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI145693193, Length=309, Percent_Identity=28.1553398058252, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789506, Length=225, Percent_Identity=23.5555555555556, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=26.8965517241379, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI48994962, Length=265, Percent_Identity=27.1698113207547, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788626, Length=296, Percent_Identity=25.6756756756757, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786401, Length=312, Percent_Identity=23.3974358974359, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788296, Length=243, Percent_Identity=23.8683127572016, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787128, Length=148, Percent_Identity=26.3513513513513, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34351; Mature: 34351

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQVRKLEDELGVMLLERTSRKVLFTQA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECC
GLLLVDQARTVLREVKVLREMASQQGESMSGPLHIGLIPTVGPYLLSHIVPMLHQAFPKL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
EMYLHESQTSQLLQQLDSGRLDCVILALVKESEAFIEVPLFDETMQLAIYADHPWADRDR
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCCCCEEEEEEECCCCCCCCC
VPMSDLAGERLLMLEDGHCLRDQAMGFCFQAGADEDTHFRATSLETLRNMVAAGSGITLL
CCHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEC
PSLAVPRERKRDGVCYLPCYRPEPKRTIALVYRPGSPLRARYEQLADCIRSHMQAYMGTG
CCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
LKQAV
HHHCC
>Mature Secondary Structure
MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQVRKLEDELGVMLLERTSRKVLFTQA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECC
GLLLVDQARTVLREVKVLREMASQQGESMSGPLHIGLIPTVGPYLLSHIVPMLHQAFPKL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
EMYLHESQTSQLLQQLDSGRLDCVILALVKESEAFIEVPLFDETMQLAIYADHPWADRDR
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCCCCEEEEEEECCCCCCCCC
VPMSDLAGERLLMLEDGHCLRDQAMGFCFQAGADEDTHFRATSLETLRNMVAAGSGITLL
CCHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEC
PSLAVPRERKRDGVCYLPCYRPEPKRTIALVYRPGSPLRARYEQLADCIRSHMQAYMGTG
CCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
LKQAV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA